Gene: Ift140 (intraflagellar transport 140) Mus musculus
Analyze
Symbol:
Ift140
Name:
intraflagellar transport 140
Description:
Involved in several processes, including cilium organization; embryonic organ development; and nervous system development. Localizes to the cytoskeleton; intraciliary transport particle A; and photoreceptor cell cilium. Used to study asphyxiating thoracic dystrophy 1 and short-rib thoracic dysplasia 9 with or without polydactyly. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Is expressed in diaphragm; lung; metanephros; and retina. Orthologous to human IFT140 (intraflagellar transport 140); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; cadmium sulfate.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
AI661311; intraflagellar transport 140 homolog; intraflagellar transport protein 140 homolog; MGC170632; mKIAA0590; T-complex expressed gene 5; Tce5; WD and tetratricopeptide repeats 2; WD and tetratricopeptide repeats protein 2; Wdtc2
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
IFT140 (intraflagellar transport 140) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):
Ift140 (intraflagellar transport 140) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Ift140 (intraflagellar transport 140) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
IFT140 (intraflagellar transport 140) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
IFT140 (intraflagellar transport 140) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ift140 (intraflagellar transport 140) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
IFT140 (intraflagellar transport 140) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
IFT140 (intraflagellar transport 140)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Rattus norvegicus (Norway rat):
Ift140 (intraflagellar transport 140)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
ift140 (intraflagellar transport 140 homolog (Chlamydomonas))
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam, ZFIN)
Caenorhabditis elegans (roundworm):
che-11
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Drosophila melanogaster (fruit fly):
rempA
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 17 25,016,083 - 25,099,499 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 17 25,153,031 - 25,236,444 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 17 24,744,323 - 24,827,086 (+) NCBI mm8 Celera 17 25,543,013 - 25,624,378 (+) NCBI Celera Cytogenetic Map 17 A3.3 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
asphyxiating thoracic dystrophy ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Jeune thoracic dystrophy ClinVar PMID:29068549 asphyxiating thoracic dystrophy ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 more ... asphyxiating thoracic dystrophy ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:23418020 more ... asphyxiating thoracic dystrophy ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 , PMID:29068549 retinitis pigmentosa ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa ClinVar PMID:26497376 retinitis pigmentosa ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa ClinVar PMID:28041643 Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: RETINITIS PIGMENTOSA 80 ClinVar PMID:26216056 Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Retinitis pigmentosa 80 ClinVar Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: RETINITIS PIGMENTOSA 80 ClinVar PMID:22503633 more ... Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: RETINITIS PIGMENTOSA 80 ClinVar PMID:22503633 more ... Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Retinal ciliopathy due to mutation in the retinitis pigmentosa-1 gene ClinVar PMID:22503633 more ... Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Retinal ciliopathy due to mutation in the retinitis pigmentosa-1 gene ClinVar PMID:29688594 Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: RETINITIS PIGMENTOSA 80 ClinVar PMID:26216056 , PMID:26968735 Retinitis Pigmentosa 80 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: RETINITIS PIGMENTOSA 80 ClinVar PMID:26968735 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by OMIM:266920 ClinVar PMID:23418020 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 more ... short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 more ... short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:26216056 , PMID:28492532 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:28288023 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 , PMID:29068549 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:23418020 , PMID:25741868 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:22503633 more ... short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:29688594 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Short-rib thoracic dysplasia without polydactyly ClinVar PMID:23418020 , PMID:29688594 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:23418020 more ... short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia ClinVar PMID:28492532 short-rib thoracic dysplasia 9 with or without polydactyly ISO RGD:1605413 8554872 ClinVar Annotator: match by OMIM:266920 ClinVar tuberous sclerosis 2 ISO RGD:1605413 8554872 ClinVar Annotator: match by term: Tuberous sclerosis 2 ClinVar PMID:28492532 , PMID:29932062
Imported Annotations - CTD
Gene-Chemical Interaction Annotations
