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Gene: Ift140 (intraflagellar transport 140) Mus musculus
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Symbol: Ift140
Name: intraflagellar transport 140
Description: Involved in several processes, including cilium organization; embryonic organ development; and nervous system development. Localizes to the cytoskeleton; intraciliary transport particle A; and photoreceptor cell cilium. Used to study asphyxiating thoracic dystrophy 1 and short-rib thoracic dysplasia 9 with or without polydactyly. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Is expressed in diaphragm; lung; metanephros; and retina. Orthologous to human IFT140 (intraflagellar transport 140); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; cadmium sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI661311; intraflagellar transport 140 homolog; intraflagellar transport protein 140 homolog; MGC170632; mKIAA0590; T-complex expressed gene 5; Tce5; WD and tetratricopeptide repeats 2; WD and tetratricopeptide repeats protein 2; Wdtc2
Orthologs:
Homo sapiens (human) : IFT140 (intraflagellar transport 140)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ift140 (intraflagellar transport 140)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ift140 (intraflagellar transport 140)
Pan paniscus (bonobo/pygmy chimpanzee) : IFT140 (intraflagellar transport 140)
Canis lupus familiaris (dog) : IFT140 (intraflagellar transport 140)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ift140 (intraflagellar transport 140)
Sus scrofa (pig) : IFT140 (intraflagellar transport 140)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381725,016,083 - 25,099,499 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371725,153,031 - 25,236,444 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,744,323 - 24,827,086 (+)NCBImm8
Celera1725,543,013 - 25,624,378 (+)NCBICelera
Cytogenetic Map17 A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ift140
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553664
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.