Ift140 (intraflagellar transport 140) - Rat Genome Database

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Gene: Ift140 (intraflagellar transport 140) Mus musculus
Analyze
Symbol: Ift140
Name: intraflagellar transport 140
RGD ID: 1553664
MGI Page MGI
Description: Acts upstream of or within several processes, including cilium organization; embryonic organ development; and nervous system development. Located in cytoskeleton and photoreceptor cell cilium. Part of intraciliary transport particle A. Is expressed in several structures, including diaphragm; lung; metanephros; retina; and secondary heart field. Used to study asphyxiating thoracic dystrophy 1 and short-rib thoracic dysplasia 9 with or without polydactyly. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Orthologous to human IFT140 (intraflagellar transport 140).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI661311; intraflagellar transport 140 homolog; intraflagellar transport protein 140 homolog; MGC170632; mKIAA0590; T-complex expressed gene 5; Tce5; WD and tetratricopeptide repeats 2; WD and tetratricopeptide repeats protein 2; Wdtc2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,235,056 - 25,318,473 (+)NCBIGRCm39mm39
GRCm39 Ensembl1725,235,059 - 25,318,469 (+)Ensembl
GRCm381725,016,083 - 25,099,499 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,016,085 - 25,099,495 (+)EnsemblGRCm38mm10GRCm38
MGSCv371725,153,031 - 25,236,444 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,744,323 - 24,827,086 (+)NCBImm8
Celera1725,543,013 - 25,624,378 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aortic arch morphology  (IEA)
abnormal atrioventricular valve morphology  (IAGP)
abnormal costovertebral joint morphology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal exoccipital bone morphology  (IAGP)
abnormal heart looping  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal hindlimb bud morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal kidney collecting duct morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal kidney physiology  (IAGP)
abnormal limb bud morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal manchette morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal mouth morphology  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal outer dense fiber morphology  (IAGP)
abnormal primary cilium morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal sperm axoneme morphology  (IAGP)
abnormal sperm end piece morphology  (IAGP)
abnormal sperm fibrous sheath morphology  (IAGP)
abnormal sperm flagellum morphology  (IAGP)
abnormal sperm head morphology  (IAGP)
abnormal sperm mitochondrial sheath morphology  (IAGP)
abnormal sperm nucleus morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermiation  (IAGP)
abnormal spermiogenesis  (IAGP)
abnormal tricuspid valve morphology  (IAGP)
absent alisphenoid bone  (IAGP)
absent facial bone  (IAGP)
absent neurocranium  (IAGP)
absent palatine bone  (IAGP)
absent spleen  (IEA)
absent tympanic ring  (IAGP)
anophthalmia  (IAGP)
asthenozoospermia  (IAGP)
atrioventricular septal defect  (IEA)
cervical vertebral fusion  (IAGP)
cleft palate  (IEA)
curly tail  (IAGP)
decreased kidney epithelial cell primary cilium length  (IAGP)
decreased sperm progressive motility  (IAGP)
dilated kidney collecting duct  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
exencephaly  (IAGP)
exostosis  (IAGP)
facial bone hypoplasia  (IAGP)
fusion of atlas and occipital bones  (IAGP)
heart hemorrhage  (IAGP)
hydrops fetalis  (IAGP)
immotile sperm  (IAGP)
impaired fertilization  (IAGP)
increased kidney apoptosis  (IAGP)
increased kidney cell proliferation  (IAGP)
kidney cortex cyst  (IAGP)
kidney cyst  (IAGP)
kidney failure  (IAGP)
kidney medulla cyst  (IAGP)
kinked sperm flagellum  (IAGP)
left pulmonary isomerism  (IEA)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
male infertility  (IAGP)
maxilla hypoplasia  (IAGP)
oligodactyly  (IAGP)
oligozoospermia  (IAGP)
omphalocele  (IAGP)
palatal shelf hypoplasia  (IAGP)
persistent truncus arteriosis  (IEA)
polydactyly  (IAGP)
premaxilla hypoplasia  (IAGP)
prenatal growth retardation  (IAGP)
renal fibrosis  (IAGP)
rib bifurcation  (IAGP)
right aortic arch  (IEA)
short sperm flagellum  (IAGP)
spina bifida  (IAGP)
teratozoospermia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Aug 31;10(4):167-80.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10899141   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11752298   PMID:12466851   PMID:12477932   PMID:15182712   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:18799693   PMID:19253336   PMID:20368623   PMID:20889716   PMID:21209331   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22282595   PMID:23418020   PMID:23469164   PMID:23955340  
PMID:24009529   PMID:24619649   PMID:25294941   PMID:25807483   PMID:27340223   PMID:27806291   PMID:29078390   PMID:29195058   PMID:29236364   PMID:29487109   PMID:29539633   PMID:31238004  
PMID:32317081   PMID:33095947   PMID:33682229   PMID:35196065  


Genomics

Comparative Map Data
Ift140
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,235,056 - 25,318,473 (+)NCBIGRCm39mm39
GRCm39 Ensembl1725,235,059 - 25,318,469 (+)Ensembl
GRCm381725,016,083 - 25,099,499 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,016,085 - 25,099,495 (+)EnsemblGRCm38mm10GRCm38
MGSCv371725,153,031 - 25,236,444 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,744,323 - 24,827,086 (+)NCBImm8
Celera1725,543,013 - 25,624,378 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
IFT140
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,510,427 - 1,612,072 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl161,510,427 - 1,612,072 (-)EnsemblGRCh38hg38GRCh38
GRCh37161,560,428 - 1,662,073 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,500,431 - 1,597,299 (-)NCBINCBI36hg18NCBI36
Celera161,772,703 - 1,874,383 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef161,486,013 - 1,587,550 (-)NCBIHuRef
CHM1_1161,560,388 - 1,662,050 (-)NCBICHM1_1
T2T-CHM13v2.0161,525,455 - 1,627,919 (-)NCBI
Ift140
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21014,032,665 - 14,121,682 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1014,032,648 - 14,120,433 (+)Ensembl
Rnor_6.01014,373,668 - 14,461,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,373,679 - 14,461,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,189,328 - 14,276,940 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,258,556 - 14,348,468 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1013,711,169 - 13,793,096 (+)NCBICelera
Cytogenetic Map10q12NCBI
Ift140
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,630,501 - 15,718,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,625,429 - 15,719,006 (+)NCBIChiLan1.0ChiLan1.0
IFT140
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1161,566,309 - 1,662,833 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,566,824 - 1,658,884 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v016130,150 - 232,369 (-)NCBIMhudiblu_PPA_v0panPan3
IFT140
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,262,887 - 39,308,912 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,295,045 - 39,308,758 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,497,349 - 40,577,227 (+)NCBI
ROS_Cfam_1.0639,574,931 - 39,655,255 (+)NCBI
ROS_Cfam_1.0 Ensembl639,577,733 - 39,655,241 (+)Ensembl
UMICH_Zoey_3.1639,252,090 - 39,332,397 (+)NCBI
UNSW_CanFamBas_1.0639,224,274 - 39,304,564 (+)NCBI
UU_Cfam_GSD_1.0639,702,970 - 39,783,289 (+)NCBI
Ift140
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,290,046 - 104,364,999 (-)NCBI
SpeTri2.0NW_0049366942,344,448 - 2,419,396 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFT140
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,309,651 - 40,372,136 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,309,298 - 40,372,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,776,363 - 41,835,312 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IFT140
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,419,432 - 1,523,342 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl51,415,664 - 1,521,843 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606829,562,562 - 29,667,409 (+)NCBIVero_WHO_p1.0
Ift140
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913621,203 - 711,493 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624913616,283 - 712,040 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AI661311  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381725,099,329 - 25,099,458UniSTSGRCm38
MGSCv371725,236,274 - 25,236,403UniSTSGRCm37
Celera1725,624,210 - 25,624,339UniSTS
Cytogenetic Map17A3.3UniSTS
Whitehead/MRC_RH17314.54UniSTS
D17Jcs42  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381725,083,301 - 25,083,485UniSTSGRCm38
MGSCv371725,220,246 - 25,220,430UniSTSGRCm37
Celera1725,608,204 - 25,608,398UniSTS
Cytogenetic Map17A3.3UniSTS
cM Map17 UniSTS
D17Jcs41  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381725,022,791 - 25,022,989UniSTSGRCm38
MGSCv371725,159,736 - 25,159,934UniSTSGRCm37
Celera1725,549,735 - 25,549,952UniSTS
Cytogenetic Map17A3.3UniSTS
cM Map17 UniSTS
D13S289  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38338,885,178 - 38,886,530UniSTSGRCm38
MGSCv37338,784,100 - 38,785,452UniSTSGRCm37
Celera1725,564,159 - 25,565,676UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map3BUniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171683545533819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
12910769Rtmq1_mrenal tumor modifier QTL 1 (mouse)172290003625721472Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1197
Count of miRNA genes:581
Interacting mature miRNAs:716
Transcripts:ENSMUST00000024983, ENSMUST00000137386, ENSMUST00000139300, ENSMUST00000140692, ENSMUST00000142000, ENSMUST00000151776, ENSMUST00000153895, ENSMUST00000156945
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_134126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC130711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF220294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI464700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY491413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB736323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC139005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ941835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY206021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX221628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX222234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ266093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV059529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000024983   ⟹   ENSMUSP00000024983
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,235,365 - 25,318,461 (+)Ensembl
GRCm38.p6 Ensembl1725,016,391 - 25,099,487 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137386   ⟹   ENSMUSP00000116163
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,235,065 - 25,311,775 (+)Ensembl
GRCm38.p6 Ensembl1725,016,091 - 25,092,801 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139300
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,309,645 - 25,312,118 (+)Ensembl
GRCm38.p6 Ensembl1725,090,671 - 25,093,144 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140692
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,264,491 - 25,306,965 (+)Ensembl
GRCm38.p6 Ensembl1725,045,517 - 25,087,991 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142000   ⟹   ENSMUSP00000156399
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,235,059 - 25,315,661 (+)Ensembl
GRCm38.p6 Ensembl1725,016,085 - 25,096,687 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151776
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,235,373 - 25,237,876 (+)Ensembl
GRCm38.p6 Ensembl1725,016,399 - 25,018,902 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153895
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,264,540 - 25,318,469 (+)Ensembl
GRCm38.p6 Ensembl1725,045,566 - 25,099,495 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156945
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,244,850 - 25,255,978 (+)Ensembl
GRCm38.p6 Ensembl1725,025,876 - 25,037,004 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232788
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1725,250,809 - 25,253,256 (+)Ensembl
GRCm38.p6 Ensembl1725,031,835 - 25,034,282 (+)Ensembl
RefSeq Acc Id: NM_134126   ⟹   NP_598887
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,060 - 25,318,473 (+)NCBI
GRCm381725,016,086 - 25,099,499 (+)NCBI
MGSCv371725,153,031 - 25,236,444 (+)RGD
Celera1725,543,013 - 25,624,378 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523402   ⟹   XP_006523465
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,141 - 25,318,461 (+)NCBI
GRCm381725,016,167 - 25,099,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006523403   ⟹   XP_006523466
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,056 - 25,318,461 (+)NCBI
GRCm381725,016,083 - 25,099,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006523404   ⟹   XP_006523467
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,102 - 25,318,461 (+)NCBI
GRCm381725,016,128 - 25,099,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006523406   ⟹   XP_006523469
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,125 - 25,299,238 (+)NCBI
GRCm381725,016,149 - 25,080,264 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006523407   ⟹   XP_006523470
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,125 - 25,285,502 (+)NCBI
GRCm381725,016,149 - 25,060,402 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006523408   ⟹   XP_006523471
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391725,235,125 - 25,299,047 (+)NCBI
GRCm381725,016,150 - 25,080,073 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_598887   ⟸   NM_134126
- UniProtKB: E9PY46 (UniProtKB/TrEMBL),   Q3TQ94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523466   ⟸   XM_006523403
- Peptide Label: isoform X1
- UniProtKB: E9PY46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523469   ⟸   XM_006523406
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006523471   ⟸   XM_006523408
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006523470   ⟸   XM_006523407
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006523467   ⟸   XM_006523404
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006523465   ⟸   XM_006523402
- Peptide Label: isoform X1
- UniProtKB: E9PY46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000116163   ⟸   ENSMUST00000137386
RefSeq Acc Id: ENSMUSP00000024983   ⟸   ENSMUST00000024983
RefSeq Acc Id: ENSMUSP00000156399   ⟸   ENSMUST00000142000

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PY46-F1-model_v2 AlphaFold E9PY46 1-1464 view protein structure

Promoters
RGD ID:13675108
Promoter ID:EPDNEW_M21703
Type:initiation region
Name:Ift140_1
Description:Mus musculus intraflagellar transport 140 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21704  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381725,016,113 - 25,016,173EPDNEW
RGD ID:13675110
Promoter ID:EPDNEW_M21704
Type:initiation region
Name:Ift140_2
Description:Mus musculus intraflagellar transport 140 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21703  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381725,016,558 - 25,016,618EPDNEW
RGD ID:6828366
Promoter ID:MM_KWN:22573
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_020608,   NM_134126,   OTTMUST00000061295,   OTTMUST00000061298,   UC008AZL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361725,152,111 - 25,153,467 (-)MPROMDB
RGD ID:6828356
Promoter ID:MM_KWN:22575
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:OTTMUST00000061300,   UC008AZO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361725,181,471 - 25,181,971 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2146906 AgrOrtholog
Ensembl Genes ENSMUSG00000024169 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000024983 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000116163 ENTREZGENE
  ENSMUSP00000116163.2 UniProtKB/TrEMBL
  ENSMUSP00000156399.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000024983 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000137386 ENTREZGENE
  ENSMUST00000137386.8 UniProtKB/TrEMBL
  ENSMUST00000142000.9 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:106633 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2146906 ENTREZGENE
NCBI Gene 106633 ENTREZGENE
PhenoGen Ift140 PhenoGen
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2W3F6_MOUSE UniProtKB/TrEMBL
  E9PY46 ENTREZGENE
  E9Q682_MOUSE UniProtKB/TrEMBL
  IF140_MOUSE UniProtKB/Swiss-Prot
  Q3TA81_MOUSE UniProtKB/TrEMBL
  Q3TQ94 ENTREZGENE, UniProtKB/TrEMBL
  Q6ZQ91_MOUSE UniProtKB/TrEMBL
  Q91VU5_MOUSE UniProtKB/TrEMBL
  Q9JIK6_MOUSE UniProtKB/TrEMBL
UniProt Secondary B2RSU5 UniProtKB/Swiss-Prot
  Q2XQY6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-04 Ift140  intraflagellar transport 140  Tce5  T-complex expressed gene 5  Data Merged 737654 PROVISIONAL
2012-07-10 Ift140  intraflagellar transport 140  Ift140  intraflagellar transport 140 homolog (Chlamydomonas)  Symbol and/or name change 5135510 APPROVED