Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hcrtr2 (hypocretin (orexin) receptor 2) Mus musculus
Analyze
Symbol: Hcrtr2
Name: hypocretin (orexin) receptor 2
Description: Exhibits orexin receptor activity. Involved in phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Used to study narcolepsy. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human HCRTR2 (hypocretin receptor 2); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; milnacipran; N-methyl-4-phenylpyridinium.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypocretin receptor type 2; mOX2aR; mOX2bR; mOXR2; orexin receptor type 2; orexin receptor type-2a; ox-2-R; ox2-R; OX2aR; OX2bR; OX2R; OXR2
Orthologs:
Homo sapiens (human) : HCRTR2 (hypocretin receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hcrtr2 (hypocretin receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hcrtr2 (hypocretin receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HCRTR2 (hypocretin receptor 2)
Canis lupus familiaris (dog) : HCRTR2 (hypocretin receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hcrtr2 (hypocretin receptor 2)
Sus scrofa (pig) : HCRTR2 (hypocretin receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38976,225,880 - 76,323,623 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37976,073,687 - 76,171,385 (-)NCBIGRCm37mm9NCBIm37
MGSCv36976,011,789 - 76,109,487 (-)NCBImm8
Celera973,390,040 - 73,487,756 (-)NCBICelera
Cytogenetic Map9 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hcrtr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553616
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.