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Gene: Plcd1 (phospholipase C, delta 1) Mus musculus
Symbol: Plcd1
Name: phospholipase C, delta 1
Description: Exhibits phospholipase C activity and phospholipid binding activity. Involved in angiogenesis; labyrinthine layer blood vessel development; and regulation of cell population proliferation. Localizes to the cytosol. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 3. Is expressed in several structures, including alimentary system; appendicular skeleton; craniocervical region; genitourinary system; and limb. Orthologous to human PLCD1 (phospholipase C delta 1); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1; AW212592; C79986; phosphoinositide phospholipase C-delta-1; phospholipase C delta 1 Lf; phospholipase C delta-1; phospholipase C-delta-1; PLC-delta 1; PLC-delta-1
Homo sapiens (human) : PLCD1 (phospholipase C delta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcd1 (phospholipase C, delta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcd1 (phospholipase C delta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCD1 (phospholipase C delta 1)
Canis lupus familiaris (dog) : PLCD1 (phospholipase C delta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcd1 (phospholipase C delta 1)
Sus scrofa (pig) : PLCD1 (phospholipase C delta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389119,071,527 - 119,093,502 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379118,980,645 - 119,002,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv369118,920,225 - 118,942,194 (-)NCBImm8
Celera9119,539,423 - 119,561,387 (-)NCBICelera
Cytogenetic Map9 F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Plcd1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553559
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.