Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF187 mRNA | CTD | PMID:22206623 | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RNF187 mRNA | CTD | PMID:33387578 | 2,4-dinitrotoluene | affects expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of RNF187 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of RNF187 mRNA | CTD | PMID:21346803 | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of RNF187 exon | CTD | PMID:33297965 | all-trans-retinoic acid | decreases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RNF187 mRNA | CTD | PMID:33167477 | antirheumatic drug | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of RNF187 mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | RNF187 (Homo sapiens) | 6480464 | Arsenic affects the methylation of RNF187 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RNF187 (Homo sapiens) | 6480464 | Arsenic affects the methylation of RNF187 gene | CTD | PMID:25304211 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of RNF187 mRNA | CTD | PMID:19770486 | bisphenol A | decreases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of RNF187 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RNF187 mRNA | CTD | PMID:33221593 | C60 fullerene | increases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | fullerene C60 results in increased expression of RNF187 mRNA | CTD | PMID:19167457 | cadmium atom | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Cadmium results in increased expression of RNF187 mRNA | CTD | PMID:24376830 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of RNF187 mRNA | CTD | PMID:37019170 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of RNF187 mRNA | CTD | PMID:27462272 | coumestrol | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RNF187 mRNA | CTD | PMID:19167446 | cyclosporin A | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RNF187 mRNA | CTD | PMID:20106945 and PMID:27989131 | dexamethasone | decreases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of RNF187 mRNA | CTD | PMID:25047013 | Enterolactone | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RNF187 mRNA | CTD | PMID:19167446 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of RNF187 mRNA | CTD | PMID:30319688 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of RNF187 mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF187 mRNA | CTD | PMID:22206623 | hydralazine | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RNF187 mRNA | CTD | PMID:17183730 | lead(0) | affects expression | ISO | RNF187 (Homo sapiens) | 6480464 | Lead affects the expression of RNF187 mRNA | CTD | PMID:28903495 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of RNF187 mRNA | CTD | PMID:34813904 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | decreases expression | ISO | RNF187 (Homo sapiens) | 6480464 | N more ... | CTD | PMID:12756304 | N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide | decreases stability | ISO | RNF187 (Homo sapiens) | 6480464 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased stability of RNF187 protein | CTD | PMID:25851810 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ro 31-8220 results in decreased stability of RNF187 protein] | CTD | PMID:25851810 | nefazodone | increases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of RNF187 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of RNF187 mRNA | CTD | PMID:24136188 | oxaliplatin | decreases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | oxaliplatin results in decreased expression of RNF187 mRNA | CTD | PMID:25729387 | oxaliplatin | multiple interactions | ISO | Rnf187 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RNF187 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of RNF187 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of RNF187 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of RNF187 mRNA | CTD | PMID:29067470 | PCB138 | decreases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | perfluorononanoic acid | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of RNF187 mRNA | CTD | PMID:32588087 | perfluorooctanoic acid | decreases expression | ISO | RNF187 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of RNF187 mRNA | CTD | PMID:25868421 | phorbol 13-acetate 12-myristate | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein | CTD | PMID:25851810 | phorbol 13-acetate 12-myristate | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] | CTD | PMID:25851810 | Ro 31-8220 | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ro 31-8220 results in decreased stability of RNF187 protein] | CTD | PMID:25851810 | Ro 31-8220 | decreases stability | ISO | RNF187 (Homo sapiens) | 6480464 | Ro 31-8220 results in decreased stability of RNF187 protein | CTD | PMID:25851810 | silicon dioxide | decreases methylation | ISO | RNF187 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased methylation of RNF187 promoter | CTD | PMID:34973136 | sunitinib | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RNF187 mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of RNF187 mRNA | CTD | PMID:16239168 | topotecan | multiple interactions | ISO | Rnf187 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RNF187 mRNA | CTD | PMID:25729387 | trichloroethene | decreases expression | ISO | Rnf187 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of RNF187 mRNA | CTD | PMID:33387578 | valproic acid | multiple interactions | ISO | RNF187 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RNF187 mRNA | CTD | PMID:17183730 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of RNF187 mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | RNF187 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RNF187 mRNA | CTD | PMID:23179753 | valproic acid | increases methylation | ISO | RNF187 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of RNF187 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RNF187 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RNF187 mRNA | CTD | PMID:25979313 | |