Prrx1 (paired related homeobox 1) - Rat Genome Database

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Gene: Prrx1 (paired related homeobox 1) Mus musculus
Analyze
Symbol: Prrx1
Name: paired related homeobox 1
RGD ID: 1553420
MGI Page MGI
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic morphogenesis; neuronal stem cell population maintenance; and regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in several structures, including brain; cardiovascular system; embryo mesenchyme; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A230024N07Rik; AA755424; AI385634; AI843499; homeobox protein K-2; homeobox protein mHox; K-2; mHo; mHox; paired mesoderm homeobox 1; paired mesoderm homeobox protein 1; paired-related homeobox protein 1; Pmx; Pmx1; Pr; PRX-1; Prx1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,072,688 - 163,142,714 (-)NCBIGRCm39mm39
GRCm39 Ensembl1163,072,688 - 163,141,279 (-)Ensembl
GRCm381163,245,119 - 163,315,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1163,245,119 - 163,313,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv371165,175,250 - 165,243,781 (-)NCBIGRCm37mm9NCBIm37
MGSCv361165,081,794 - 165,150,325 (-)NCBImm8
Celera1165,686,221 - 165,753,419 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map170.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal ameloblast differentiation  (IAGP)
abnormal ameloblast morphology  (IAGP)
abnormal aortic arch and aortic arch branch attachment  (IAGP)
abnormal aortic arch morphology  (IAGP)
abnormal apical ectodermal ridge morphology  (IAGP)
abnormal artery morphology  (IAGP)
abnormal autopod morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal carpal bone morphology  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal cervical atlas morphology  (IAGP)
abnormal cervical axis morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal ear position  (IAGP)
abnormal epiphyseal plate morphology  (IAGP)
abnormal fetal ductus arteriosus morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal forelimb zeugopod morphology  (IAGP)
abnormal hindlimb zeugopod morphology  (IAGP)
abnormal hyoid bone morphology  (IAGP)
abnormal incisor morphology  (IAGP)
abnormal incudostapedial joint morphology  (IAGP)
abnormal incus morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal long bone hypertrophic chondrocyte zone  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal lumbar vertebrae morphology  (IAGP)
abnormal lung vasculature morphology  (IAGP)
abnormal malleus manubrium morphology  (IAGP)
abnormal malleus morphology  (IAGP)
abnormal malleus processus brevis morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal Meckel's cartilage morphology  (IAGP)
abnormal metacarpal bone morphology  (IAGP)
abnormal metatarsal bone morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal odontoblast differentiation  (IAGP)
abnormal oval window morphology  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal pulmonary trunk morphology  (IAGP)
abnormal respiration  (IAGP)
abnormal scapular spine morphology  (IAGP)
abnormal stapes crus morpholgy  (IAGP)
abnormal stapes morphology  (IAGP)
abnormal stylohyoid ligament morphology  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal tibia morphology  (IAGP)
abnormal tongue morphology  (IAGP)
abnormal tooth development  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal ulna morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal vertebral arch morphology  (IAGP)
absent alisphenoid bone  (IAGP)
absent eyelids  (IAGP)
absent gonial bone  (IAGP)
absent incisors  (IAGP)
absent lateral semicircular canal  (IAGP)
absent maxillary shelf  (IAGP)
absent maxillary zygomatic process  (IAGP)
absent Meckel's cartilage  (IAGP)
absent palatine bone horizontal plate  (IAGP)
absent pubic symphysis  (IAGP)
absent stapes obturator foramen  (IAGP)
absent supraoccipital bone  (IAGP)
absent temporal bone squamous part  (IAGP)
absent temporomandibular joint  (IAGP)
absent triquetrum  (IAGP)
absent tympanic ring  (IAGP)
absent vertebral arch  (IAGP)
absent zygomatic arch  (IAGP)
absent zygomatic bone  (IAGP)
alisphenoid bone hypoplasia  (IAGP)
anotia  (IAGP)
aphagia  (IAGP)
bowed radius  (IAGP)
bowed tibia  (IAGP)
bowed ulna  (IAGP)
cleft palate  (IAGP)
cleft secondary palate  (IAGP)
cyanosis  (IAGP)
decreased body size  (IAGP)
decreased width of hypertrophic chondrocyte zone  (IAGP)
delayed bone ossification  (IAGP)
distended abdomen  (IAGP)
ectopic cartilage  (IAGP)
ectopic digits  (IAGP)
eyelids open at birth  (IAGP)
fused tarsal bones  (IAGP)
growth retardation of incisors  (IAGP)
long limbs  (IAGP)
lowered ear position  (IAGP)
mandible hypoplasia  (IAGP)
maxillary shelf hypoplasia  (IAGP)
microcephaly  (IAGP)
micrognathia  (IAGP)
neonatal lethality  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
oligodactyly  (IAGP)
outer ear hypoplasia  (IAGP)
palatal shelf hypoplasia  (IAGP)
pointed snout  (IAGP)
polydactyly  (IAGP)
postaxial polydactyly  (IAGP)
preaxial polydactyly  (IAGP)
pterygoid bone hypoplasia  (IAGP)
pulmonary hypoplasia  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
retroesophageal right subclavian artery  (IAGP)
short fibula  (IAGP)
short limbs  (IAGP)
short malleus manubrium  (IAGP)
short mandible  (IAGP)
short Meckel's cartilage  (IAGP)
short radius  (IAGP)
short tibia  (IAGP)
short ulna  (IAGP)
small ears  (IAGP)
small otic capsule  (IAGP)
spina bifida  (IAGP)
syndactyly  (IAGP)
xiphoid process foramen  (IAGP)
References

Additional References at PubMed
PMID:1360403   PMID:1383943   PMID:7554933   PMID:7577675   PMID:7592824   PMID:7758948   PMID:7910581   PMID:7964557   PMID:8075499   PMID:8889548   PMID:9053326   PMID:9205120  
PMID:9636074   PMID:9671575   PMID:9729491   PMID:9786416   PMID:9817598   PMID:9876178   PMID:9882503   PMID:10349636   PMID:10354604   PMID:10625532   PMID:10664157   PMID:10748458  
PMID:10804186   PMID:10976045   PMID:11042159   PMID:11063257   PMID:11076861   PMID:11520673   PMID:11532916   PMID:11685458   PMID:11747080   PMID:11748565   PMID:12114523   PMID:12163022  
PMID:12193642   PMID:12351180   PMID:12414734   PMID:12477932   PMID:14681479   PMID:14727108   PMID:15117820   PMID:15173589   PMID:15226823   PMID:15459107   PMID:15618518   PMID:15936012  
PMID:15944189   PMID:16141072   PMID:16141073   PMID:16169709   PMID:16297875   PMID:16492970   PMID:16582099   PMID:16893423   PMID:16971476   PMID:16998126   PMID:17586524   PMID:17609113  
PMID:17764670   PMID:17967808   PMID:18198333   PMID:18287559   PMID:18296734   PMID:18458156   PMID:18554416   PMID:19419974   PMID:19587446   PMID:19690384   PMID:19777594   PMID:20059953  
PMID:20211142   PMID:20412781   PMID:20534727   PMID:20683885   PMID:20932939   PMID:21156168   PMID:21267068   PMID:21309073   PMID:21455939   PMID:21677750   PMID:21776009   PMID:21779340  
PMID:21826198   PMID:21873635   PMID:22174793   PMID:22438573   PMID:22510988   PMID:23250756   PMID:23355395   PMID:23447615   PMID:23473983   PMID:23475960   PMID:24146773   PMID:24289074  
PMID:24424161   PMID:24662046   PMID:24778262   PMID:24952961   PMID:25162226   PMID:26685160   PMID:26726832   PMID:26947973   PMID:26984772   PMID:27546376   PMID:28366454   PMID:28455376  
PMID:30002136   PMID:30071041   PMID:31171666   PMID:31712603   PMID:32005677   PMID:32188878  


Genomics

Comparative Map Data
Prrx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,072,688 - 163,142,714 (-)NCBIGRCm39mm39
GRCm39 Ensembl1163,072,688 - 163,141,279 (-)Ensembl
GRCm381163,245,119 - 163,315,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1163,245,119 - 163,313,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv371165,175,250 - 165,243,781 (-)NCBIGRCm37mm9NCBIm37
MGSCv361165,081,794 - 165,150,325 (-)NCBImm8
Celera1165,686,221 - 165,753,419 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map170.53NCBI
PRRX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1170,662,728 - 170,739,421 (+)EnsemblGRCh38hg38GRCh38
GRCh381170,662,728 - 170,739,421 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371170,633,272 - 170,708,562 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,899,937 - 168,975,165 (+)NCBINCBI36hg18NCBI36
Celera1143,742,929 - 143,818,153 (+)NCBI
Cytogenetic Map1q24.2NCBI
HuRef1141,857,178 - 141,932,397 (+)NCBIHuRef
CHM1_11172,055,608 - 172,130,854 (+)NCBICHM1_1
Prrx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21375,600,777 - 75,671,896 (-)NCBI
Rnor_6.0 Ensembl1381,147,348 - 81,214,546 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01381,147,038 - 81,215,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01386,039,713 - 86,107,919 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41378,961,648 - 79,028,882 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11378,975,835 - 79,043,069 (-)NCBI
Celera1375,343,320 - 75,409,614 (-)NCBICelera
Cytogenetic Map13q22NCBI
Prrx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554626,919,899 - 6,991,733 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554626,919,905 - 6,991,733 (+)NCBIChiLan1.0ChiLan1.0
PRRX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11149,867,365 - 149,943,810 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1149,867,634 - 149,943,810 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01146,151,633 - 146,227,926 (+)NCBIMhudiblu_PPA_v0panPan3
PRRX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1728,065,570 - 28,138,734 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl728,068,711 - 28,138,787 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha727,598,170 - 27,671,127 (-)NCBI
ROS_Cfam_1.0727,867,506 - 27,940,906 (-)NCBI
UMICH_Zoey_3.1727,717,090 - 27,790,221 (-)NCBI
UNSW_CanFamBas_1.0727,751,956 - 27,825,122 (-)NCBI
UU_Cfam_GSD_1.0727,988,098 - 28,061,291 (-)NCBI
Prrx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934498,358,502 - 98,426,095 (-)NCBI
SpeTri2.0NW_00493648116,208,243 - 16,272,836 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRRX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl480,427,685 - 80,501,646 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1480,427,682 - 80,502,689 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2487,973,831 - 88,044,655 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRRX1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12558,347,686 - 58,423,454 (-)NCBI
ChlSab1.1 Ensembl2558,347,704 - 58,421,980 (-)Ensembl
Prrx1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248268,361,039 - 8,435,488 (+)NCBI

Position Markers
AA755424  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381163,245,863 - 163,245,977UniSTSGRCm38
MGSCv371165,175,994 - 165,176,108UniSTSGRCm37
Celera1165,686,965 - 165,687,079UniSTS
Cytogenetic Map1H2.1UniSTS
Whitehead/MRC_RH12075.26UniSTS
AI843499  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381163,255,483 - 163,255,615UniSTSGRCm38
MGSCv371165,185,614 - 165,185,746UniSTSGRCm37
Celera1165,696,568 - 165,696,700UniSTS
Cytogenetic Map1H2.1UniSTS
Whitehead/MRC_RH12075.06UniSTS
Prrx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371165,176,953 - 165,177,458UniSTSGRCm37
Celera1165,687,928 - 165,688,433UniSTS
Cytogenetic Map1H2.1UniSTS
cM Map185.4UniSTS
D1Mit506  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381163,306,348 - 163,306,466UniSTSGRCm38
MGSCv371165,236,479 - 165,236,597UniSTSGRCm37
Celera1165,746,095 - 165,746,209UniSTS
Cytogenetic Map1H2.1UniSTS
cM Map186.6UniSTS
Whitehead Genetic184.2UniSTS
AI385634  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381163,312,799 - 163,312,900UniSTSGRCm38
MGSCv371165,242,930 - 165,243,031UniSTSGRCm37
Cytogenetic Map1H2.1UniSTS
Whitehead/MRC_RH12075.06UniSTS
Prrx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.1UniSTS
Prrx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381163,246,822 - 163,247,327UniSTSGRCm38
MGSCv371165,176,953 - 165,177,458UniSTSGRCm37
Celera1165,687,928 - 165,688,433UniSTS
Cytogenetic Map1H2.1UniSTS
cM Map185.4UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135919071169919261Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1147032461167758653Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129255120163255255Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136334204170334348Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131228571165311895Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1136002150170002264Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1301232Hcs7_mhepatocarcinogenesis susceptibility 7 (mouse)Not determined1156774467168358833Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147249520169211344Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1163149528186261999Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156774467170976071Mouse
14746980Manh50_mmandible shape 50 (mouse)1134255813168255813Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
13452394Leusq1_mleucocytosis susceptibility QTL 1 (mouse)1156774467168358833Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4593
Count of miRNA genes:908
Interacting mature miRNAs:1268
Transcripts:ENSMUST00000027878, ENSMUST00000075805, ENSMUST00000174098, ENSMUST00000174397, ENSMUST00000183691
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006496703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB221686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC120173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U03873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X59725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X59726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027878   ⟹   ENSMUSP00000027878
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1163,245,119 - 163,313,710 (-)Ensembl
RefSeq Acc Id: ENSMUST00000075805   ⟹   ENSMUSP00000075203
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1163,245,119 - 163,313,672 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174098
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1163,282,819 - 163,313,671 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174397   ⟹   ENSMUSP00000134338
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1163,252,866 - 163,313,668 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183691
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1163,247,577 - 163,289,224 (-)Ensembl
RefSeq Acc Id: NM_001025570   ⟹   NP_001020741
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391163,082,846 - 163,141,219 (-)NCBI
GRCm381163,255,277 - 163,313,650 (-)NCBI
MGSCv371165,175,250 - 165,243,781 (-)RGD
Celera1165,686,221 - 165,753,419 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011127   ⟹   NP_035257
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391163,072,688 - 163,141,219 (-)NCBI
GRCm381163,245,119 - 163,313,650 (-)NCBI
MGSCv371165,175,250 - 165,243,781 (-)RGD
Celera1165,686,221 - 165,753,419 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_175686   ⟹   NP_783617
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391163,072,688 - 163,141,219 (-)NCBI
GRCm381163,245,119 - 163,313,650 (-)NCBI
MGSCv371165,175,250 - 165,243,781 (-)RGD
Celera1165,686,221 - 165,753,419 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006496703   ⟹   XP_006496766
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391163,077,254 - 163,142,714 (-)NCBI
GRCm381163,250,027 - 163,315,145 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035257   ⟸   NM_011127
- Peptide Label: isoform a
- UniProtKB: P63013 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_783617   ⟸   NM_175686
- Peptide Label: isoform b
- UniProtKB: P63013 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001020741   ⟸   NM_001025570
- Peptide Label: isoform c
- UniProtKB: G3UZ44 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006496766   ⟸   XM_006496703
- Peptide Label: isoform X1
- UniProtKB: P63013 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000027878   ⟸   ENSMUST00000027878
RefSeq Acc Id: ENSMUSP00000134338   ⟸   ENSMUST00000174397
RefSeq Acc Id: ENSMUSP00000075203   ⟸   ENSMUST00000075805
Protein Domains
Homeobox   OAR

Promoters
RGD ID:6875488
Promoter ID:EPDNEW_M1194
Type:initiation region
Name:Prrx1_2
Description:Mus musculus paired related homeobox 1 , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1195  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381163,313,478 - 163,313,538EPDNEW
RGD ID:6875490
Promoter ID:EPDNEW_M1195
Type:multiple initiation site
Name:Prrx1_1
Description:Mus musculus paired related homeobox 1 , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1194  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381163,313,668 - 163,313,728EPDNEW
RGD ID:6817296
Promoter ID:MM_KWN:2663
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   MEF_B4,   MEF_B6
Transcripts:UC007DHJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361165,183,096 - 165,186,262 (-)MPROMDB
RGD ID:6818287
Promoter ID:MM_KWN:2664
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   MEF_B4,   MEF_B6
Transcripts:NM_001025570,   NM_011127,   NM_175686
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361165,242,576 - 165,244,612 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97712 AgrOrtholog
Ensembl Genes ENSMUSG00000026586 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000027878 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000075203 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000134338 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027878 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000075805 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000174397 ENTREZGENE, UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OAR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRRX1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18933 UniProtKB/Swiss-Prot
MGD MGI:97712 ENTREZGENE
NCBI Gene 18933 ENTREZGENE
PANTHER PTHR46385 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prrx1 PhenoGen
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3UZ44 ENTREZGENE, UniProtKB/TrEMBL
  P63013 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TMI4_MOUSE UniProtKB/TrEMBL
  Q8BGB1_MOUSE UniProtKB/TrEMBL
  Q9D861_MOUSE UniProtKB/TrEMBL
  Q9D8E1_MOUSE UniProtKB/TrEMBL
UniProt Secondary P43271 UniProtKB/Swiss-Prot
  Q02810 UniProtKB/Swiss-Prot
  Q569N6 UniProtKB/Swiss-Prot