Or6c65 (olfactory receptor family 6 subfamily C member 65) - Rat Genome Database

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Gene: Or6c65 (olfactory receptor family 6 subfamily C member 65) Mus musculus
Analyze
Symbol: Or6c65
Name: olfactory receptor family 6 subfamily C member 65
RGD ID: 1553332
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR6C65 (olfactory receptor family 6 subfamily C member 65).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2PULF-11446184-11447122; MOR112; MOR112-2; olfactory receptor 808; olfactory receptor MOR112-2; Olfr808
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm20553   Or6ab1-ps1   Or6o1-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910129,603,367 - 129,604,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10129,601,351 - 129,607,582 (+)EnsemblGRCm39 Ensembl
GRCm3810129,767,498 - 129,768,436 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10129,765,482 - 129,771,713 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710129,204,554 - 129,205,492 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610129,170,447 - 129,171,385 (+)NCBIMGSCv36mm8
Celera10132,153,275 - 132,154,213 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or6c65
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910129,603,367 - 129,604,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10129,601,351 - 129,607,582 (+)EnsemblGRCm39 Ensembl
GRCm3810129,767,498 - 129,768,436 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10129,765,482 - 129,771,713 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710129,204,554 - 129,205,492 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610129,170,447 - 129,171,385 (+)NCBIMGSCv36mm8
Celera10132,153,275 - 132,154,213 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.51NCBI
OR6C65
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,400,529 - 55,401,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,400,529 - 55,401,467 (+)EnsemblGRCh38hg38GRCh38
GRCh371255,794,313 - 55,795,251 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,080,580 - 54,081,518 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,080,579 - 54,081,518NCBI
Celera1255,446,597 - 55,447,535 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1252,833,097 - 52,834,035 (+)NCBIHuRef
CHM1_11255,761,106 - 55,762,044 (+)NCBICHM1_1
T2T-CHM13v2.01255,367,089 - 55,368,027 (+)NCBIT2T-CHM13v2.0
Olr947
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr874,160,583 - 4,161,521 (-)NCBIGRCr8
mRatBN7.273,511,569 - 3,512,507 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl73,511,569 - 3,512,507 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx76,339,647 - 6,340,585 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.078,215,327 - 8,216,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.077,461,111 - 7,461,954 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl77,461,109 - 7,461,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.077,559,423 - 7,560,266 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.474,776,529 - 4,777,467 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.174,776,528 - 4,777,467 (-)NCBI
Cytogenetic Map7q11NCBI
OR6C69G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.127112,712 - 113,647 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl27112,712 - 113,647 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2746,166,740 - 46,167,675 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.027117,874 - 118,809 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl27117,874 - 118,809 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.127111,905 - 112,840 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.027113,520 - 114,455 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02746,547,947 - 46,548,882 (-)NCBIUU_Cfam_GSD_1.0
LOC100620277
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2521,686,058 - 21,687,064 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Or6c65
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:44
Interacting mature miRNAs:44
Transcripts:ENSMUST00000060636
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108515907130530862Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108515907130530862Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108575094130530862Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108575094130530862Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108575094130530862Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108575094130530862Mouse

Markers in Region
UniSTS:491743  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810129,767,470 - 129,768,500UniSTSGRCm38
MGSCv3710129,204,526 - 129,205,556UniSTSGRCm37
Celera10132,153,247 - 132,154,277UniSTS
Cytogenetic Map10D3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000060636   ⟹   ENSMUSP00000059714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10129,603,367 - 129,604,305 (+)Ensembl
GRCm38.p6 Ensembl10129,767,498 - 129,768,436 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203236   ⟹   ENSMUSP00000145315
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10129,601,351 - 129,607,582 (+)Ensembl
GRCm38.p6 Ensembl10129,765,482 - 129,771,713 (+)Ensembl
RefSeq Acc Id: NM_146928   ⟹   NP_667139
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910129,603,367 - 129,604,305 (+)NCBI
GRCm3810129,767,498 - 129,768,436 (+)NCBI
MGSCv3710129,204,554 - 129,205,492 (+)RGD
Celera10132,153,275 - 132,154,213 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_667139 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL60823 (Get FASTA)   NCBI Sequence Viewer  
  AAP71297 (Get FASTA)   NCBI Sequence Viewer  
  EDL24674 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000059714
  ENSMUSP00000059714.2
  ENSMUSP00000145315.2
Reference Protein Sequences
RefSeq Acc Id: NP_667139   ⟸   NM_146928
- UniProtKB: Q8VGI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000145315   ⟸   ENSMUST00000203236
RefSeq Acc Id: ENSMUSP00000059714   ⟸   ENSMUST00000060636
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VGI8-F1-model_v2 AlphaFold Q8VGI8 1-312 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030642 AgrOrtholog
Ensembl Genes ENSMUSG00000049894 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000060636 ENTREZGENE
  ENSMUST00000060636.2 UniProtKB/TrEMBL
  ENSMUST00000203236.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
KEGG Report mmu:258930 UniProtKB/TrEMBL
MGD MGI:3030642 ENTREZGENE
NCBI Gene 258930 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 6C65 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6c65 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VGI8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or6c65  olfactory receptor family 6 subfamily C member 65  Olfr808  olfactory receptor 808  Symbol and/or name change 5135510 APPROVED