Gvin1 (GTPase, very large interferon inducible 1) - Rat Genome Database

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Gene: Gvin1 (GTPase, very large interferon inducible 1) Mus musculus
Analyze
No known orthologs.
Symbol: Gvin1
Name: GTPase, very large interferon inducible 1
RGD ID: 1553320
MGI Page MGI
Description: Orthologous to human GVINP1 (GTPase, very large interferon inducible pseudogene 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9130002C22Rik; 9830104F22Rik; Ii; Iigs1; interferon inducible GTPase 1; interferon-induced very large GTPase 1; V; very large-inducible GTPase-1; VLI; VLIG; VLIG-1
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Pseudogenes: Gvin-ps2   Gvin-ps3   Gvin-ps4   Gvin-ps5   Gvin-ps6  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,755,742 - 105,814,547 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,755,763 - 105,814,533 (-)EnsemblGRCm39 Ensembl
GRCm387106,156,535 - 106,215,340 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7106,156,556 - 106,215,326 (-)EnsemblGRCm38mm10GRCm38
MGSCv377113,300,049 - 113,358,854 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,950,205 - 106,008,975 (-)NCBIMGSCv36mm8
Celera7106,168,566 - 106,205,231 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11544199   PMID:12477932   PMID:12874213   PMID:16141072   PMID:16141073   PMID:21267068   PMID:28378742   PMID:29459677   PMID:30409884  


Genomics

Variants

.
Variants in Gvin1
1262 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:452
Count of miRNA genes:182
Interacting mature miRNAs:191
Transcripts:ENSMUST00000006667, ENSMUST00000183409
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
13464255Ifvrq2_minfluenza virus resistance QTL 2 (mouse)792500698106455693Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000006667   ⟹   ENSMUSP00000006667
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7105,755,763 - 105,814,517 (-)Ensembl
GRCm38.p6 Ensembl7106,156,556 - 106,215,310 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183409   ⟹   ENSMUSP00000138950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7105,755,763 - 105,814,533 (-)Ensembl
GRCm38.p6 Ensembl7106,156,556 - 106,215,326 (-)Ensembl
RefSeq Acc Id: NM_001039160   ⟹   NP_001034249
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,755,742 - 105,814,547 (-)NCBI
GRCm387106,156,535 - 106,215,340 (-)NCBI
MGSCv377113,300,049 - 113,358,854 (-)RGD
Celera7106,168,566 - 106,548,452 (-)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_029000   ⟹   NP_083276
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,755,742 - 105,814,547 (-)NCBI
GRCm387106,156,535 - 106,215,340 (-)NCBI
MGSCv377113,300,049 - 113,358,854 (-)RGD
Celera7106,168,566 - 106,548,452 (-)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017312356   ⟹   XP_017167845
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,755,986 - 105,775,167 (-)NCBI
GRCm387106,156,779 - 106,175,960 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034249 (Get FASTA)   NCBI Sequence Viewer  
  NP_083276 (Get FASTA)   NCBI Sequence Viewer  
  XP_017167845 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE32834 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000006667
  ENSMUSP00000006667.4
  ENSMUSP00000138950
  ENSMUSP00000138950.2
GenBank Protein Q80SU7 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_083276   ⟸   NM_029000
- UniProtKB: L7N451 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001034249   ⟸   NM_001039160
- UniProtKB: L7N451 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017167845   ⟸   XM_017312356
- Peptide Label: isoform X1
- UniProtKB: L7N451 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138950   ⟸   ENSMUST00000183409
RefSeq Acc Id: ENSMUSP00000006667   ⟸   ENSMUST00000006667
Protein Domains
VLIG-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80SU7-F1-model_v2 AlphaFold Q80SU7 1-2427 view protein structure

Promoters
RGD ID:8665145
Promoter ID:EPDNEW_M10604
Type:multiple initiation site
Name:Gvin1_2
Description:Mus musculus GTPase, very large interferon inducible 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10605  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387106,212,525 - 106,212,585EPDNEW
RGD ID:8665147
Promoter ID:EPDNEW_M10605
Type:initiation region
Name:Gvin1_1
Description:Mus musculus GTPase, very large interferon inducible 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10604  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387106,215,326 - 106,215,386EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921808 AgrOrtholog
Ensembl Genes ENSMUSG00000045868 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000006667 ENTREZGENE
  ENSMUST00000006667.11 UniProtKB/TrEMBL
  ENSMUST00000183409 ENTREZGENE
  ENSMUST00000183409.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Alpha/beta_knot_MTases UniProtKB/TrEMBL
  G_VLIG_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report mmu:74558 UniProtKB/TrEMBL
MGD MGI:1921808 ENTREZGENE
NCBI Gene 74558 ENTREZGENE
PANTHER GTP-BINDING UniProtKB/TrEMBL
  INTERFERON-INDUCED VERY LARGE GTPASE 1 UniProtKB/TrEMBL
PhenoGen Gvin1 PhenoGen
PROSITE G_VLIG UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF75217 UniProtKB/TrEMBL
UniProt L7N451 ENTREZGENE, UniProtKB/TrEMBL
  Q80SU7 ENTREZGENE