Mocs2 (molybdenum cofactor synthesis 2) - Rat Genome Database

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Gene: Mocs2 (molybdenum cofactor synthesis 2) Mus musculus
Analyze
Symbol: Mocs2
Name: molybdenum cofactor synthesis 2
RGD ID: 1553221
MGI Page MGI
Description: Enables identical protein binding activity. Involved in molybdopterin cofactor biosynthetic process. Predicted to be located in nuclear speck. Predicted to be part of molybdopterin synthase complex. Predicted to be active in cytosol. Is expressed in several structures, including brain; genitourinary system; skin; spleen; and stomach. Used to study molybdenum cofactor deficiency type B. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Orthologous to human MOCS2 (molybdenum cofactor synthesis 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI415403; MOCS2A; MOCS2B; molybdenum cofactor synthesis protein 2 large subunit; molybdenum cofactor synthesis protein 2 small subunit; molybdenum cofactor synthesis protein 2A; molybdenum cofactor synthesis protein 2B; molybdopterin synthase sulfur carrier subunit; sulfur carrier protein MOCS2A
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913114,954,707 - 114,965,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13114,954,772 - 114,968,811 (+)EnsemblGRCm39 Ensembl
GRCm3813114,818,160 - 114,829,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13114,818,236 - 114,832,275 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713115,608,445 - 115,619,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613115,939,164 - 115,949,607 (+)NCBIMGSCv36mm8
Celera13119,161,937 - 119,173,119 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Cell biology of molybdenum. Mendel RR and Bittner F, Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and GEPH. Reiss J and Johnson JL, Hum Mutat 2003 Jun;21(6):569-76.
8. Human molybdopterin synthase gene: genomic structure and mutations in molybdenum cofactor deficiency type B. Reiss J, etal., Am J Hum Genet 1999 Mar;64(3):706-11.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Human molybdopterin synthase gene: identification of a bicistronic transcript with overlapping reading frames. Stallmeyer B, etal., Am J Hum Genet 1999 Mar;64(3):698-705.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11591653   PMID:12477932   PMID:12732628   PMID:15073332   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821  
PMID:19521500   PMID:21267068   PMID:21677750   PMID:21873635   PMID:27138983   PMID:27626380   PMID:30810871   PMID:38355793   PMID:39159974  


Genomics

Comparative Map Data
Mocs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913114,954,707 - 114,965,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13114,954,772 - 114,968,811 (+)EnsemblGRCm39 Ensembl
GRCm3813114,818,160 - 114,829,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13114,818,236 - 114,832,275 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713115,608,445 - 115,619,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613115,939,164 - 115,949,607 (+)NCBIMGSCv36mm8
Celera13119,161,937 - 119,173,119 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.61NCBI
MOCS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38553,095,679 - 53,109,757 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl553,095,679 - 53,110,063 (-)EnsemblGRCh38hg38GRCh38
GRCh37552,391,509 - 52,405,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36552,429,649 - 52,441,355 (-)NCBINCBI36Build 36hg18NCBI36
Build 34552,429,653 - 52,441,355NCBI
Celera549,347,470 - 49,359,176 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef549,363,558 - 49,377,653 (-)NCBIHuRef
CHM1_1552,394,058 - 52,408,152 (-)NCBICHM1_1
T2T-CHM13v2.0553,923,465 - 53,937,543 (-)NCBIT2T-CHM13v2.0
Mocs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8248,237,655 - 48,249,394 (+)NCBIGRCr8
mRatBN7.2246,504,588 - 46,516,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl246,504,588 - 46,516,324 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx253,614,202 - 53,625,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0251,672,578 - 51,684,324 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0246,540,417 - 46,552,139 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0246,980,964 - 46,992,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl246,980,976 - 46,992,883 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,520,174 - 71,532,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4246,948,321 - 46,960,060 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1246,876,587 - 46,888,290 (+)NCBI
Celera242,260,839 - 42,272,490 (+)NCBICelera
Cytogenetic Map2q14NCBI
Mocs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544614,295,737 - 14,307,838 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544614,295,737 - 14,305,735 (+)NCBIChiLan1.0ChiLan1.0
MOCS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2460,831,376 - 60,843,005 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1558,984,997 - 58,996,220 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0560,920,268 - 60,931,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1562,539,208 - 62,550,926 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl562,539,214 - 62,550,921 (+)Ensemblpanpan1.1panPan2
MOCS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1462,153,828 - 62,164,154 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl462,153,296 - 62,185,492 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha461,928,792 - 61,939,117 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0462,651,866 - 62,662,174 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl462,652,443 - 62,665,845 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1462,427,116 - 62,437,429 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0462,551,658 - 62,561,990 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0463,078,354 - 63,088,687 (+)NCBIUU_Cfam_GSD_1.0
Mocs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213205,369,033 - 205,380,226 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648014,302,824 - 14,313,265 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOCS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1632,436,205 - 32,462,521 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11632,427,783 - 32,462,362 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21634,270,548 - 34,290,713 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MOCS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1449,387,923 - 49,399,902 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl449,386,487 - 49,399,928 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660821,727,742 - 1,739,745 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mocs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247596,261,933 - 6,271,509 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247596,261,970 - 6,272,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mocs2
454 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3085
Count of miRNA genes:754
Interacting mature miRNAs:992
Transcripts:ENSMUST00000015680, ENSMUST00000050131, ENSMUST00000164737, ENSMUST00000164871, ENSMUST00000165022, ENSMUST00000165669, ENSMUST00000166104, ENSMUST00000166176, ENSMUST00000170985, ENSMUST00000183407, ENSMUST00000184046, ENSMUST00000184214, ENSMUST00000184245, ENSMUST00000184282, ENSMUST00000184335, ENSMUST00000184672, ENSMUST00000184781
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142334Svtms_msurvival time modifier of Sod2 (mouse)Not determined13107613580119476372Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse
1357468Rplag_mreduced platelet aggregation (mouse)Not determined1395502130120883175Mouse
12879496Fexq2_mfear expression QTL 2 (mouse)13100741519120883175Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
4141704Hipq1_mhyperinsulin production QTL 1 (mouse)Not determined110409487119476372Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1395036824120883175Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394528399120883175Mouse
4141826Tbqt5_mtibia bone quality traits 5 (mouse)Not determined13103341617117043216Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
4142400Tgq24_mtriglyceride QTL 24 (mouse)Not determined102602630120883175Mouse
14746974Manh75_mmandible shape 75 (mouse)1399386647120883175Mouse

Markers in Region
AI415403  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3813114,828,423 - 114,828,615UniSTSGRCm38
MGSCv3713115,618,631 - 115,618,823UniSTSGRCm37
Celera13119,172,122 - 119,172,314UniSTS
Cytogenetic Map13D2.2UniSTS
Whitehead/MRC_RH13992.32UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001113374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001113375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF091872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX220128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000015680   ⟹   ENSMUSP00000015680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,813 - 114,965,259 (+)Ensembl
GRCm38.p6 Ensembl13114,818,277 - 114,828,723 (+)Ensembl
Ensembl Acc Id: ENSMUST00000050131
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,813 - 114,962,058 (+)Ensembl
GRCm38.p6 Ensembl13114,818,277 - 114,825,522 (+)Ensembl
Ensembl Acc Id: ENSMUST00000164737   ⟹   ENSMUSP00000133069
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,823 - 114,965,080 (+)Ensembl
GRCm38.p6 Ensembl13114,818,287 - 114,828,544 (+)Ensembl
Ensembl Acc Id: ENSMUST00000164871   ⟹   ENSMUSP00000131816
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,955,441 - 114,961,766 (+)Ensembl
GRCm38.p6 Ensembl13114,818,905 - 114,825,230 (+)Ensembl
Ensembl Acc Id: ENSMUST00000165022   ⟹   ENSMUSP00000128965
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,822 - 114,965,267 (+)Ensembl
GRCm38.p6 Ensembl13114,818,286 - 114,828,731 (+)Ensembl
Ensembl Acc Id: ENSMUST00000165669
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,780 - 114,957,604 (+)Ensembl
GRCm38.p6 Ensembl13114,818,244 - 114,821,068 (+)Ensembl
Ensembl Acc Id: ENSMUST00000166104   ⟹   ENSMUSP00000129021
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,772 - 114,965,259 (+)Ensembl
GRCm38.p6 Ensembl13114,818,236 - 114,828,723 (+)Ensembl
Ensembl Acc Id: ENSMUST00000166176   ⟹   ENSMUSP00000125797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,795 - 114,966,066 (+)Ensembl
GRCm38.p6 Ensembl13114,818,259 - 114,829,530 (+)Ensembl
Ensembl Acc Id: ENSMUST00000170985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,806 - 114,965,542 (+)Ensembl
GRCm38.p6 Ensembl13114,818,270 - 114,829,006 (+)Ensembl
Ensembl Acc Id: ENSMUST00000183407   ⟹   ENSMUSP00000139011
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,836 - 114,965,251 (+)Ensembl
GRCm38.p6 Ensembl13114,818,300 - 114,828,715 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184046   ⟹   ENSMUSP00000138936
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,806 - 114,965,210 (+)Ensembl
GRCm38.p6 Ensembl13114,818,270 - 114,828,674 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184214   ⟹   ENSMUSP00000139285
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,819 - 114,962,784 (+)Ensembl
GRCm38.p6 Ensembl13114,818,283 - 114,826,248 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184245   ⟹   ENSMUSP00000139355
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,807 - 114,968,811 (+)Ensembl
GRCm38.p6 Ensembl13114,818,271 - 114,832,275 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,794 - 114,958,524 (+)Ensembl
GRCm38.p6 Ensembl13114,818,258 - 114,821,988 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184335   ⟹   ENSMUSP00000139064
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,799 - 114,965,018 (+)Ensembl
GRCm38.p6 Ensembl13114,818,263 - 114,828,482 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184672   ⟹   ENSMUSP00000139298
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,842 - 114,965,265 (+)Ensembl
GRCm38.p6 Ensembl13114,818,306 - 114,828,729 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184781   ⟹   ENSMUSP00000138856
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13114,954,830 - 114,965,259 (+)Ensembl
GRCm38.p6 Ensembl13114,818,294 - 114,828,723 (+)Ensembl
RefSeq Acc Id: NM_001113374   ⟹   NP_001106845
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
GRCm3813114,818,237 - 114,829,420 (+)ENTREZGENE
MGSCv3713115,608,445 - 115,619,628 (+)RGD
Celera13119,161,937 - 119,173,119 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001113375   ⟹   NP_001106846
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
GRCm3813114,818,237 - 114,829,420 (+)ENTREZGENE
MGSCv3713115,608,445 - 115,619,628 (+)RGD
Celera13119,161,937 - 119,173,119 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001426246   ⟹   NP_001413175
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
RefSeq Acc Id: NM_001426247   ⟹   NP_001413176
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
RefSeq Acc Id: NM_001426248   ⟹   NP_001413177
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
RefSeq Acc Id: NM_001426249   ⟹   NP_001413178
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
RefSeq Acc Id: NM_001426250   ⟹   NP_001413179
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
RefSeq Acc Id: NM_013826   ⟹   NP_038854
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,794 - 114,965,960 (+)NCBI
GRCm3813114,818,237 - 114,829,420 (+)ENTREZGENE
MGSCv3713115,608,445 - 115,619,628 (+)RGD
Celera13119,161,937 - 119,173,119 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030247178   ⟹   XP_030103038
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913114,954,707 - 114,965,543 (+)NCBI
GRCm3813114,818,160 - 114,829,008 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001106845 (Get FASTA)   NCBI Sequence Viewer  
  NP_001106846 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413175 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413176 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413177 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413178 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413179 (Get FASTA)   NCBI Sequence Viewer  
  NP_038854 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103038 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD14600 (Get FASTA)   NCBI Sequence Viewer  
  AAD14601 (Get FASTA)   NCBI Sequence Viewer  
  AAH24371 (Get FASTA)   NCBI Sequence Viewer  
  BAB22306 (Get FASTA)   NCBI Sequence Viewer  
  BAB26707 (Get FASTA)   NCBI Sequence Viewer  
  BAC37393 (Get FASTA)   NCBI Sequence Viewer  
  EDL18371 (Get FASTA)   NCBI Sequence Viewer  
  EDL18372 (Get FASTA)   NCBI Sequence Viewer  
  EDL18373 (Get FASTA)   NCBI Sequence Viewer  
  EDL18374 (Get FASTA)   NCBI Sequence Viewer  
  EDL18375 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000015680
  ENSMUSP00000015680.5
  ENSMUSP00000125797
  ENSMUSP00000125797.2
  ENSMUSP00000128965.2
  ENSMUSP00000129021
  ENSMUSP00000129021.2
  ENSMUSP00000131816.3
  ENSMUSP00000133069
  ENSMUSP00000133069.2
  ENSMUSP00000138856.2
  ENSMUSP00000138936.2
  ENSMUSP00000139011.2
  ENSMUSP00000139064
  ENSMUSP00000139064.2
  ENSMUSP00000139285.2
  ENSMUSP00000139298.2
  ENSMUSP00000139355
  ENSMUSP00000139355.2
GenBank Protein Q9Z223 (Get FASTA)   NCBI Sequence Viewer  
  Q9Z224 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_038854   ⟸   NM_013826
- Peptide Label: isoform Mocs2A
- UniProtKB: Q9Z224 (UniProtKB/Swiss-Prot),   Q9D6Q0 (UniProtKB/Swiss-Prot),   F6ZGI7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106845   ⟸   NM_001113374
- Peptide Label: isoform Mocs2B
- UniProtKB: Q9DCK1 (UniProtKB/Swiss-Prot),   Q8R1M7 (UniProtKB/Swiss-Prot),   Q8C5E5 (UniProtKB/Swiss-Prot),   Q9Z223 (UniProtKB/Swiss-Prot),   A0A0R4J206 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106846   ⟸   NM_001113375
- Peptide Label: isoform Mocs2B2
- UniProtKB: Q9Z223 (UniProtKB/Swiss-Prot),   Q9DCK1 (UniProtKB/Swiss-Prot),   Q8R1M7 (UniProtKB/Swiss-Prot),   Q8C5E5 (UniProtKB/Swiss-Prot),   E9PVP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030103038   ⟸   XM_030247178
- Peptide Label: isoform X1
- UniProtKB: Q9Z223 (UniProtKB/Swiss-Prot),   Q9DCK1 (UniProtKB/Swiss-Prot),   Q8R1M7 (UniProtKB/Swiss-Prot),   Q8C5E5 (UniProtKB/Swiss-Prot),   A0A0R4J206 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000138936   ⟸   ENSMUST00000184046
Ensembl Acc Id: ENSMUSP00000139285   ⟸   ENSMUST00000184214
Ensembl Acc Id: ENSMUSP00000139355   ⟸   ENSMUST00000184245
Ensembl Acc Id: ENSMUSP00000133069   ⟸   ENSMUST00000164737
Ensembl Acc Id: ENSMUSP00000131816   ⟸   ENSMUST00000164871
Ensembl Acc Id: ENSMUSP00000139064   ⟸   ENSMUST00000184335
Ensembl Acc Id: ENSMUSP00000138856   ⟸   ENSMUST00000184781
Ensembl Acc Id: ENSMUSP00000139298   ⟸   ENSMUST00000184672
Ensembl Acc Id: ENSMUSP00000139011   ⟸   ENSMUST00000183407
Ensembl Acc Id: ENSMUSP00000015680   ⟸   ENSMUST00000015680
Ensembl Acc Id: ENSMUSP00000129021   ⟸   ENSMUST00000166104
Ensembl Acc Id: ENSMUSP00000125797   ⟸   ENSMUST00000166176
Ensembl Acc Id: ENSMUSP00000128965   ⟸   ENSMUST00000165022
RefSeq Acc Id: NP_001413179   ⟸   NM_001426250
- Peptide Label: isoform Mocs2A
- UniProtKB: F6ZGI7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413178   ⟸   NM_001426249
- Peptide Label: isoform Mocs2A
- UniProtKB: F6ZGI7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413175   ⟸   NM_001426246
- Peptide Label: isoform Mocs2B3
RefSeq Acc Id: NP_001413177   ⟸   NM_001426248
- Peptide Label: isoform Mocs2B5
RefSeq Acc Id: NP_001413176   ⟸   NM_001426247
- Peptide Label: isoform Mocs2B4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z223-F1-model_v2 AlphaFold Q9Z223 1-189 view protein structure

Promoters
RGD ID:8681354
Promoter ID:EPDNEW_M18707
Type:initiation region
Name:Mocs2_1
Description:Mus musculus molybdenum cofactor synthesis 2 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3813114,818,258 - 114,818,318EPDNEW
RGD ID:6824157
Promoter ID:MM_KWN:15325
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000050131,   NM_001113374,   NM_001113375,   NM_013826,   UC007RXT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3613115,608,356 - 115,608,862 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1336894 AgrOrtholog
Ensembl Genes ENSMUSG00000015536 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000015680 ENTREZGENE
  ENSMUST00000015680.11 UniProtKB/TrEMBL
  ENSMUST00000164737 ENTREZGENE
  ENSMUST00000164737.8 UniProtKB/TrEMBL
  ENSMUST00000164871.3 UniProtKB/TrEMBL
  ENSMUST00000165022.9 UniProtKB/TrEMBL
  ENSMUST00000166104 ENTREZGENE
  ENSMUST00000166104.9 UniProtKB/TrEMBL
  ENSMUST00000166176 ENTREZGENE
  ENSMUST00000166176.9 UniProtKB/TrEMBL
  ENSMUST00000183407.2 UniProtKB/TrEMBL
  ENSMUST00000184046.8 UniProtKB/TrEMBL
  ENSMUST00000184214.8 UniProtKB/TrEMBL
  ENSMUST00000184245 ENTREZGENE
  ENSMUST00000184245.8 UniProtKB/TrEMBL
  ENSMUST00000184335 ENTREZGENE
  ENSMUST00000184335.8 UniProtKB/TrEMBL
  ENSMUST00000184672.8 UniProtKB/TrEMBL
  ENSMUST00000184781.8 UniProtKB/TrEMBL
Gene3D-CATH 3.10.20.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1170.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta-grasp_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MoaE_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOCS2A UniProtKB/Swiss-Prot
  MOCS2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOCS2A UniProtKB/TrEMBL
  MOCS2B_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mopterin_biosynth_MoaE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mopterin_synth/thiamin_S_b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ThiS/MoaD-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17434 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1336894 ENTREZGENE
NCBI Gene 17434 ENTREZGENE
PANTHER MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOLYBDOPTERIN SYNTHASE RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR33359 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MoaE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ThiS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mocs2 PhenoGen
Superfamily-SCOP SSF54285 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54690 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J206 ENTREZGENE, UniProtKB/TrEMBL
  E9PUX1_MOUSE UniProtKB/TrEMBL
  E9PVP5 ENTREZGENE, UniProtKB/TrEMBL
  F6ZGI7 ENTREZGENE, UniProtKB/TrEMBL
  MOC2A_MOUSE UniProtKB/Swiss-Prot
  MOC2B_MOUSE UniProtKB/Swiss-Prot
  Q8C5E5 ENTREZGENE
  Q8R1M7 ENTREZGENE
  Q9D6Q0 ENTREZGENE
  Q9DCK1 ENTREZGENE
  Q9Z223 ENTREZGENE
  Q9Z224 ENTREZGENE
  V9GX15_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q8C5E5 UniProtKB/Swiss-Prot
  Q8R1M7 UniProtKB/Swiss-Prot
  Q9D6Q0 UniProtKB/Swiss-Prot
  Q9DCK1 UniProtKB/Swiss-Prot