Taar1 (trace amine-associated receptor 1) - Rat Genome Database

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Gene: Taar1 (trace amine-associated receptor 1) Mus musculus
Analyze
Symbol: Taar1
Name: trace amine-associated receptor 1
RGD ID: 1553140
MGI Page MGI
Description: Enables trace-amine receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and phospholipase C-activating G protein-coupled receptor signaling pathway. Acts upstream of or within G protein-coupled receptor signaling pathway. Is active in plasma membrane. Used to study schizophrenia. Orthologous to human TAAR1 (trace amine associated receptor 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ta; taR-1; Tar1; Tr; trace amine receptor 1; Trar1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,796,304 - 23,797,302 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,796,254 - 23,797,367 (+)EnsemblGRCm39 Ensembl
GRCm381023,920,406 - 23,921,404 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1023,920,356 - 23,921,469 (+)EnsemblGRCm38mm10GRCm38
MGSCv371023,640,212 - 23,641,210 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,609,822 - 23,610,820 (+)NCBIMGSCv36mm8
Celera1024,853,896 - 24,854,894 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
schizophrenia  (IAGP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Trace amines: identification of a family of mammalian G protein-coupled receptors. Borowsky B, etal., Proc Natl Acad Sci U S A 2001 Jul 31;98(16):8966-71.
2. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Lindemann L, etal., Genomics 2005 Mar;85(3):372-85.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16602821   PMID:16878137   PMID:17212650   PMID:17218486   PMID:17556730   PMID:17900709   PMID:18083911   PMID:19725810   PMID:19892733   PMID:20976142   PMID:21073468  
PMID:21267068   PMID:21525407   PMID:21873635   PMID:22114263   PMID:22442117   PMID:22763617   PMID:22840399   PMID:23624375   PMID:24565640   PMID:24925023   PMID:25721394   PMID:25740289  
PMID:25749299   PMID:26468205   PMID:26601071   PMID:27031617   PMID:27055611   PMID:27919403   PMID:28919515   PMID:29403379   PMID:31274109   PMID:31320495   PMID:31399635   PMID:31409621  
PMID:31570011   PMID:31925906   PMID:32424970   PMID:33579534   PMID:33753244   PMID:34145232   PMID:34445611   PMID:34512422   PMID:36380156   PMID:36430544   PMID:37225986   PMID:37369127  
PMID:37591886   PMID:37935376   PMID:37963465   PMID:38514038   PMID:38658737  


Genomics

Comparative Map Data
Taar1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,796,304 - 23,797,302 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,796,254 - 23,797,367 (+)EnsemblGRCm39 Ensembl
GRCm381023,920,406 - 23,921,404 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1023,920,356 - 23,921,469 (+)EnsemblGRCm38mm10GRCm38
MGSCv371023,640,212 - 23,641,210 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,609,822 - 23,610,820 (+)NCBIMGSCv36mm8
Celera1024,853,896 - 24,854,894 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.39NCBI
TAAR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,643,312 - 132,659,182 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,643,312 - 132,659,182 (-)EnsemblGRCh38hg38GRCh38
GRCh376132,964,451 - 132,980,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366133,007,816 - 133,008,835 (-)NCBINCBI36Build 36hg18NCBI36
Build 346133,007,815 - 133,008,835NCBI
Celera6133,712,961 - 133,713,980 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,541,047 - 130,542,066 (-)NCBIHuRef
CHM1_16133,229,781 - 133,230,800 (-)NCBICHM1_1
T2T-CHM13v2.06133,838,279 - 133,854,151 (-)NCBIT2T-CHM13v2.0
Taar1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,336,978 - 23,337,976 (-)NCBIGRCr8
mRatBN7.2121,517,742 - 21,518,740 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,517,258 - 21,532,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,297,006 - 21,298,004 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,297,051 - 27,298,049 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,494,378 - 21,495,376 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,595,477 - 22,596,475 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,595,477 - 22,596,475 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,070,405 - 24,071,403 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,045,364 - 22,046,362 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1122,048,308 - 22,049,307 (-)NCBI
Celera120,260,820 - 20,261,818 (-)NCBICelera
Cytogenetic Map1p12NCBI
Taar1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543613,205,777 - 13,206,793 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543613,204,876 - 13,207,928 (-)NCBIChiLan1.0ChiLan1.0
LOC100977974
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25152,626,456 - 152,642,289 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16150,533,544 - 150,549,377 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06130,420,169 - 130,436,032 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16134,529,110 - 134,530,455 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6134,529,418 - 134,530,437 (-)Ensemblpanpan1.1panPan2
TAAR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha126,633,763 - 26,634,809 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,557,860 - 25,558,906 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,557,860 - 25,558,906 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,603,937 - 25,604,983 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,502,722 - 25,503,768 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,765,932 - 25,766,978 (-)NCBIUU_Cfam_GSD_1.0
Taar1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946120,896,284 - 120,897,306 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936560675,500 - 676,522 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936560675,500 - 676,522 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAAR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1131,037,826 - 31,050,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,568,566 - 34,570,037 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAAR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11340,874,400 - 40,891,408 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1340,889,682 - 40,890,698 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604013,078,475 - 13,081,371 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Taar1
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:94
Interacting mature miRNAs:95
Transcripts:ENSMUST00000051532
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532718Sluc44f_msusceptibility to lung cancer 44f (mouse)10126289265Mouse
1300881Sluc29_msusceptibility to lung cancer 29 (mouse)Not determined10126289265Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
11532717Sluc44g_msusceptibility to lung cancer 44g (mouse)10126289265Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1300759Geot_mgeotaxia (mouse)Not determined10126289265Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
1301659Arrd2_mage-related retinal degeneration 2 (mouse)Not determined102028318526890391Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10440815438408276Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
11532725Sluc44b_msusceptibility to lung cancer 44b (mouse)10126289265Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
11532724Sluc44c_msusceptibility to lung cancer 44c (mouse)10126289265Mouse
11532723Sluc44d_msusceptibility to lung cancer 44d (mouse)10126289265Mouse
11532722Sluc44e_msusceptibility to lung cancer 44e (mouse)10126289265Mouse
1558857Igan1_mIgA nephropathy 1 (mouse)Not determined101771831329704155Mouse
11532721Sluc44_msusceptibility to lung cancer 44 (mouse)10126289265Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
11532720Sluc44a_msusceptibility to lung cancer 44a (mouse)10126289265Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
11533917Mts2_mmammary tumor susceptibility 2 (mouse)10126289265Mouse
13208570Bmiq9_mbody mass index QTL 9 (mouse)101287574424875898Mouse
1301796Mop2_mmorphine preference 2 (mouse)Not determined10928911929028424Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
Taar1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381023,920,512 - 23,921,337UniSTSGRCm38
MGSCv371023,640,318 - 23,641,143UniSTSGRCm37
Celera1024,854,002 - 24,854,827UniSTS
Cytogenetic Map10A3UniSTS
cM Map10 UniSTS
UniSTS:488210  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381023,920,406 - 23,921,404UniSTSGRCm38
MGSCv371023,640,212 - 23,641,210UniSTSGRCm37
Celera1024,853,896 - 24,854,894UniSTS
Cytogenetic Map10A3UniSTS
UniSTS:494010  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381023,920,356 - 23,921,469UniSTSGRCm38
MGSCv371023,640,162 - 23,641,275UniSTSGRCm37
Celera1024,853,846 - 24,854,959UniSTS
Cytogenetic Map10A3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000051532   ⟹   ENSMUSP00000049527
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1023,796,254 - 23,797,367 (+)Ensembl
GRCm38.p6 Ensembl1023,920,356 - 23,921,469 (+)Ensembl
RefSeq Acc Id: NM_053205   ⟹   NP_444435
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391023,796,304 - 23,797,302 (+)NCBI
GRCm381023,920,406 - 23,921,404 (+)ENTREZGENE
MGSCv371023,640,212 - 23,641,210 (+)RGD
Celera1024,853,896 - 24,854,894 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_444435 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI25369 (Get FASTA)   NCBI Sequence Viewer  
  AAI25371 (Get FASTA)   NCBI Sequence Viewer  
  AAK71238 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000049527
  ENSMUSP00000049527.5
GenBank Protein Q923Y8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_444435   ⟸   NM_053205
- UniProtKB: Q05A85 (UniProtKB/Swiss-Prot),   Q923Y8 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000049527   ⟸   ENSMUST00000051532

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q923Y8-F1-model_v2 AlphaFold Q923Y8 1-332 view protein structure

Promoters
RGD ID:8671658
Promoter ID:EPDNEW_M13860
Type:single initiation site
Name:Taar1_1
Description:Mus musculus trace amine-associated receptor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381023,920,357 - 23,920,417EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2148258 AgrOrtholog
Ensembl Genes ENSMUSG00000056379 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000051532 ENTREZGENE
  ENSMUST00000051532.5 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  TAAR UniProtKB/Swiss-Prot
  TAAR1 UniProtKB/Swiss-Prot
  TAAR_fam UniProtKB/Swiss-Prot
KEGG Report mmu:111174 UniProtKB/Swiss-Prot
MGD MGI:2148258 ENTREZGENE
NCBI Gene 111174 ENTREZGENE
PANTHER HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
  TRACE AMINE-ASSOCIATED RECEPTOR 1 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Taar1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  TRACEAMINE1R UniProtKB/Swiss-Prot
  TRACEAMINER UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt Q05A85 ENTREZGENE
  Q923Y8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q05A85 UniProtKB/Swiss-Prot