Nmnat3 (nicotinamide nucleotide adenylyltransferase 3) - Rat Genome Database

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Gene: Nmnat3 (nicotinamide nucleotide adenylyltransferase 3) Mus musculus
Analyze
Symbol: Nmnat3
Name: nicotinamide nucleotide adenylyltransferase 3
RGD ID: 1553136
MGI Page MGI
Description: Enables nicotinamide-nucleotide adenylyltransferase activity. Acts upstream of or within NAD biosynthetic process and response to wounding. Located in mitochondrion. Is expressed in several structures, including alimentary system; hemolymphoid system; liver; retina; and urinary system. Orthologous to human NMNAT3 (nicotinamide nucleotide adenylyltransferase 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4933408N02Rik; MGC102340; naMN adenylyltransferase 1; naMN adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; nicotinamide-nucleotide adenylyltransferase 3; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3; nicotinate-nucleotide adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NMN/NaMN adenylyltransferase 3; PN; PNAT3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,169,487 - 98,302,586 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,169,488 - 98,302,491 (+)EnsemblGRCm39 Ensembl
GRCm38998,287,433 - 98,420,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,287,435 - 98,420,438 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,197,002 - 98,311,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,105,935 - 98,220,780 (+)NCBIMGSCv36mm8
Celera997,850,409 - 97,963,936 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (ISO)
mitochondrion  (IBA,IDA,ISO)
neuronal cell body  (ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Houtkooper RH, etal., Endocr Rev. 2010 Apr;31(2):194-223. doi: 10.1210/er.2009-0026. Epub 2009 Dec 9.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration. Kitaoka Y, etal., Cell Death Dis. 2013 Oct 17;4:e860. doi: 10.1038/cddis.2013.391.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14681479   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16618939   PMID:16914673   PMID:17967808  
PMID:19439605   PMID:21267068   PMID:21873635   PMID:23082226   PMID:23946398   PMID:24739386   PMID:26624618   PMID:26756334   PMID:27423420   PMID:27428041   PMID:29901258   PMID:30166529  
PMID:30550785   PMID:30671537   PMID:31511627   PMID:32325033   PMID:33107823   PMID:36375251  


Genomics

Comparative Map Data
Nmnat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,169,487 - 98,302,586 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,169,488 - 98,302,491 (+)EnsemblGRCm39 Ensembl
GRCm38998,287,433 - 98,420,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,287,435 - 98,420,438 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,197,002 - 98,311,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,105,935 - 98,220,780 (+)NCBIMGSCv36mm8
Celera997,850,409 - 97,963,936 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.35NCBI
NMNAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,560,180 - 139,678,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,560,180 - 139,678,017 (-)EnsemblGRCh38hg38GRCh38
GRCh373139,279,022 - 139,396,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,761,723 - 140,879,530 (-)NCBINCBI36Build 36hg18NCBI36
Build 343140,761,731 - 140,879,538NCBI
Celera3137,701,933 - 137,819,739 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,654,467 - 136,772,328 (-)NCBIHuRef
CHM1_13139,242,474 - 139,360,320 (-)NCBICHM1_1
T2T-CHM13v2.03142,307,606 - 142,425,486 (-)NCBIT2T-CHM13v2.0
Nmnat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,771,124 - 107,888,528 (+)NCBIGRCr8
mRatBN7.2898,892,168 - 99,003,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl898,873,398 - 99,020,645 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,561,145 - 104,672,788 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,760,392 - 102,872,044 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,602,906 - 100,714,552 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,317,038 - 106,429,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,317,124 - 106,429,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08105,760,369 - 105,871,374 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,472,426 - 103,584,246 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18103,491,880 - 103,603,693 (+)NCBI
Celera898,304,722 - 98,415,332 (+)NCBICelera
Cytogenetic Map8q31NCBI
Nmnat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555085,913,898 - 6,022,128 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555085,909,808 - 6,024,301 (+)NCBIChiLan1.0ChiLan1.0
NMNAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,472,086 - 137,592,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,476,826 - 137,597,430 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,594,825 - 136,715,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13144,196,529 - 144,313,658 (-)NCBIpanpan1.1PanPan1.1panPan2
NMNAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,714,162 - 35,829,150 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,714,933 - 35,829,049 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2335,701,815 - 35,816,030 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02336,250,931 - 36,365,957 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,250,934 - 36,366,221 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,933,008 - 36,047,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02336,006,480 - 36,121,350 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,249,065 - 36,363,588 (-)NCBIUU_Cfam_GSD_1.0
Nmnat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,886,743 - 75,026,495 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,636,380 - 1,766,306 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,653,243 - 1,766,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMNAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,429,639 - 80,556,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,431,405 - 80,556,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21388,294,211 - 88,321,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NMNAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11550,880,146 - 50,990,958 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1550,880,235 - 50,991,281 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604123,853,934 - 23,964,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmnat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473016,158,485 - 16,231,670 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473016,151,185 - 16,289,260 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nmnat3
4160 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1600
Count of miRNA genes:579
Interacting mature miRNAs:698
Transcripts:ENSMUST00000035031, ENSMUST00000112935, ENSMUST00000112937, ENSMUST00000112938, ENSMUST00000129771, ENSMUST00000134253, ENSMUST00000141427
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966089077100089175Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967006220101006220Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968779563102779705Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968779563102779705Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969121898103121973Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96926774798701707Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969428566103428698Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976024387101406120Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001357445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_144533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030244660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC144809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB661406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF472005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000112935   ⟹   ENSMUSP00000108557
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,178,636 - 98,293,487 (+)Ensembl
GRCm38.p6 Ensembl998,296,583 - 98,411,434 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112937   ⟹   ENSMUSP00000108559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,178,715 - 98,293,444 (+)Ensembl
GRCm38.p6 Ensembl998,296,662 - 98,411,391 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112938   ⟹   ENSMUSP00000108560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,178,657 - 98,302,491 (+)Ensembl
GRCm38.p6 Ensembl998,296,604 - 98,420,438 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129771
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,169,508 - 98,250,213 (+)Ensembl
GRCm38.p6 Ensembl998,287,455 - 98,368,160 (+)Ensembl
RefSeq Acc Id: ENSMUST00000134253   ⟹   ENSMUSP00000141111
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,169,488 - 98,281,569 (+)Ensembl
GRCm38.p6 Ensembl998,287,435 - 98,399,516 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,178,657 - 98,237,810 (+)Ensembl
GRCm38.p6 Ensembl998,296,604 - 98,355,757 (+)Ensembl
RefSeq Acc Id: NM_001357445   ⟹   NP_001344374
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,623 - 98,293,481 (+)NCBI
GRCm38998,296,570 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001357446   ⟹   NP_001344375
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,623 - 98,293,481 (+)NCBI
GRCm38998,296,570 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001357449   ⟹   NP_001344378
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,623 - 98,302,586 (+)NCBI
GRCm38998,296,570 - 98,420,533 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001357451   ⟹   NP_001344380
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,623 - 98,302,586 (+)NCBI
GRCm38998,296,570 - 98,420,533 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001357452   ⟹   NP_001344381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,623 - 98,302,586 (+)NCBI
GRCm38998,296,570 - 98,420,533 (+)NCBI
Sequence:
RefSeq Acc Id: NM_144533   ⟹   NP_653116
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,623 - 98,293,481 (+)NCBI
GRCm38998,296,570 - 98,411,428 (+)NCBI
MGSCv37998,197,002 - 98,311,847 (+)RGD
Celera997,850,409 - 97,963,936 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006511502   ⟹   XP_006511565
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,603 - 98,293,481 (+)NCBI
GRCm38998,296,550 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006511503   ⟹   XP_006511566
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,603 - 98,293,481 (+)NCBI
GRCm38998,296,550 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006511504   ⟹   XP_006511567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,603 - 98,293,481 (+)NCBI
GRCm38998,296,550 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011242826   ⟹   XP_011241128
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,169,487 - 98,293,481 (+)NCBI
GRCm38998,287,433 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011242827   ⟹   XP_011241129
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,169,487 - 98,293,481 (+)NCBI
GRCm38998,287,433 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030244660   ⟹   XP_030100520
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,179,043 - 98,293,481 (+)NCBI
GRCm38998,296,989 - 98,411,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036155348   ⟹   XP_036011241
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,178,603 - 98,293,481 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_653116   ⟸   NM_144533
- Peptide Label: isoform a
- UniProtKB: Q58E37 (UniProtKB/Swiss-Prot),   Q99JR6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006511565   ⟸   XM_006511502
- Peptide Label: isoform X1
- UniProtKB: Q58E37 (UniProtKB/Swiss-Prot),   Q99JR6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006511566   ⟸   XM_006511503
- Peptide Label: isoform X1
- UniProtKB: Q58E37 (UniProtKB/Swiss-Prot),   Q99JR6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006511567   ⟸   XM_006511504
- Peptide Label: isoform X1
- UniProtKB: Q58E37 (UniProtKB/Swiss-Prot),   Q99JR6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011241128   ⟸   XM_011242826
- Peptide Label: isoform X1
- UniProtKB: Q58E37 (UniProtKB/Swiss-Prot),   Q99JR6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011241129   ⟸   XM_011242827
- Peptide Label: isoform X1
- UniProtKB: Q58E37 (UniProtKB/Swiss-Prot),   Q99JR6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001344378   ⟸   NM_001357449
- Peptide Label: isoform d
- UniProtKB: Q3V3F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001344381   ⟸   NM_001357452
- Peptide Label: isoform d
- UniProtKB: Q3V3F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001344380   ⟸   NM_001357451
- Peptide Label: isoform d
- UniProtKB: Q3V3F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001344375   ⟸   NM_001357446
- Peptide Label: isoform c
RefSeq Acc Id: NP_001344374   ⟸   NM_001357445
- Peptide Label: isoform b
- UniProtKB: Q3V3C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030100520   ⟸   XM_030244660
- Peptide Label: isoform X1
- UniProtKB: Q99JR6 (UniProtKB/Swiss-Prot),   Q58E37 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000108560   ⟸   ENSMUST00000112938
RefSeq Acc Id: ENSMUSP00000108559   ⟸   ENSMUST00000112937
RefSeq Acc Id: ENSMUSP00000108557   ⟸   ENSMUST00000112935
RefSeq Acc Id: ENSMUSP00000141111   ⟸   ENSMUST00000134253
RefSeq Acc Id: XP_036011241   ⟸   XM_036155348
- Peptide Label: isoform X2
Protein Domains
Cytidyltransferase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99JR6-F1-model_v2 AlphaFold Q99JR6 1-245 view protein structure

Promoters
RGD ID:6844880
Promoter ID:MM_KWN:58463
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000112937,   ENSMUST00000112938,   NM_144533,   OTTMUST00000054280
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36998,196,964 - 98,197,464 (+)MPROMDB
RGD ID:8670524
Promoter ID:EPDNEW_M13292
Type:initiation region
Name:Nmnat3_3
Description:Mus musculus nicotinamide nucleotide adenylyltransferase 3 ,transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13293  EPDNEW_M13294  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38998,287,455 - 98,287,515EPDNEW
RGD ID:8670526
Promoter ID:EPDNEW_M13293
Type:initiation region
Name:Nmnat3_1
Description:Mus musculus nicotinamide nucleotide adenylyltransferase 3 ,transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13292  EPDNEW_M13294  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38998,296,604 - 98,296,664EPDNEW
RGD ID:8670528
Promoter ID:EPDNEW_M13294
Type:multiple initiation site
Name:Nmnat3_2
Description:Mus musculus nicotinamide nucleotide adenylyltransferase 3 ,transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13292  EPDNEW_M13293  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38998,296,868 - 98,296,928EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921330 AgrOrtholog
Ensembl Genes ENSMUSG00000032456 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112935 ENTREZGENE
  ENSMUST00000112935.8 UniProtKB/Swiss-Prot
  ENSMUST00000112937 ENTREZGENE
  ENSMUST00000112937.3 UniProtKB/TrEMBL
  ENSMUST00000112938 ENTREZGENE
  ENSMUST00000112938.8 UniProtKB/TrEMBL
  ENSMUST00000134253.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_trans-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NadD/NMNAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NMNAT_euk UniProtKB/Swiss-Prot
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74080 UniProtKB/Swiss-Prot
MGD MGI:1921330 ENTREZGENE
NCBI Gene 74080 ENTREZGENE
PANTHER NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CTP_transf_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nmnat3 PhenoGen
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WSM7_MOUSE UniProtKB/TrEMBL
  NMNA3_MOUSE UniProtKB/Swiss-Prot
  Q3V3C7 ENTREZGENE, UniProtKB/TrEMBL
  Q3V3F1 ENTREZGENE, UniProtKB/TrEMBL
  Q58E37 ENTREZGENE
  Q99JR6 ENTREZGENE
UniProt Secondary Q58E37 UniProtKB/Swiss-Prot