Or1af1 (olfactory receptor family 1 subfamily AF member 1) - Rat Genome Database

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Gene: Or1af1 (olfactory receptor family 1 subfamily AF member 1) Mus musculus
Analyze
No known orthologs.
Symbol: Or1af1
Name: olfactory receptor family 1 subfamily AF member 1
RGD ID: 1553133
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2NLDC-33902472-33903401; MOR138; MOR138-5P; MOR138-6; olfactory receptor 366; olfactory receptor MOR138-5P; Olfr366
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39237,109,503 - 37,110,432 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl237,101,586 - 37,114,518 (+)EnsemblGRCm39 Ensembl
GRCm38237,219,491 - 37,220,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl237,211,574 - 37,224,506 (+)EnsemblGRCm38mm10GRCm38
MGSCv37237,075,011 - 37,075,940 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36237,041,500 - 37,042,429 (+)NCBIMGSCv36mm8
Celera236,902,472 - 36,903,401 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10706615   PMID:11802173   PMID:11875048   PMID:14611657   PMID:15081110   PMID:21267068   PMID:21873635   PMID:25417106   PMID:32295537  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:33
Interacting mature miRNAs:34
Transcripts:ENSMUST00000091001
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
13464253Ifvrq1_minfluenza virus resistance QTL 1 (mouse)23303449252034492Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000091001   ⟹   ENSMUSP00000088524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl237,109,503 - 37,110,432 (+)Ensembl
GRCm38.p6 Ensembl237,219,491 - 37,220,420 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214897   ⟹   ENSMUSP00000150608
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl237,101,586 - 37,114,518 (+)Ensembl
GRCm38.p6 Ensembl237,211,574 - 37,224,506 (+)Ensembl
RefSeq Acc Id: NM_001005569   ⟹   NP_001005569
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39237,109,503 - 37,110,432 (+)NCBI
GRCm38237,219,491 - 37,220,420 (+)ENTREZGENE
MGSCv37237,075,011 - 37,075,940 (+)RGD
Celera236,902,472 - 36,903,401 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001005569 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD43416 (Get FASTA)   NCBI Sequence Viewer  
  AAP70897 (Get FASTA)   NCBI Sequence Viewer  
  EDL08702 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000088524
  ENSMUSP00000088524.2
  ENSMUSP00000150608.2
Reference Protein Sequences
RefSeq Acc Id: NP_001005569   ⟸   NM_001005569
- UniProtKB: Q7TRY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000088524   ⟸   ENSMUST00000091001
RefSeq Acc Id: ENSMUSP00000150608   ⟸   ENSMUST00000214897
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRY4-F1-model_v2 AlphaFold Q7TRY4 1-309 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030200 AgrOrtholog
Ensembl Genes ENSMUSG00000068947 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000091001 ENTREZGENE
  ENSMUST00000091001.2 UniProtKB/TrEMBL
  ENSMUST00000214897.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:236509 UniProtKB/TrEMBL
MGD MGI:3030200 ENTREZGENE
NCBI Gene 236509 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1af1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TRY4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-21 Or1af1  olfactory receptor family 1 subfamily AF member 1  Olfr366  olfactory receptor 366  Symbol and/or name change 5135510 APPROVED