Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Acy3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ACY3 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | decreases expression | EXP | | 6480464 | vinylidene chloride results in decreased expression of ACY3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ACY3 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACY3 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of ACY3 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ACY3 mRNA | CTD | PMID:17942748 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ACY3 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ACY3 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ACY3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ACY3 mRNA | CTD | PMID:18796159 and PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ACY3 mRNA | CTD | PMID:21354282 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 3-chloropropane-1,2-diol | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in decreased expression of ACY3 protein | CTD | PMID:26597043 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of ACY3 gene | CTD | PMID:31683443 | acetamide | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of ACY3 mRNA | CTD | PMID:31881176 | Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of ACY3 mRNA | CTD | PMID:23650126 | atrazine | increases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of ACY3 mRNA | CTD | PMID:22378314 | Benoxacor | increases expression | EXP | | 6480464 | benoxacor results in increased expression of ACY3 mRNA | CTD | PMID:34850242 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to ACY3 promoter] | CTD | PMID:19654925 | benzo[a]pyrene | decreases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ACY3 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | ACY3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ACY3 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | ACY3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ACY3 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | ACY3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ACY3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ACY3 mRNA | CTD | PMID:22228805 | bisphenol A | affects expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ACY3 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases methylation | ISO | ACY3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ACY3 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ACY3 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ACY3 mRNA | CTD | PMID:32145629 and PMID:34947998 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of ACY3 mRNA | CTD | PMID:30951980 | cadmium atom | multiple interactions | ISO | ACY3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ACY3 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases methylation | ISO | Acy3 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of ACY3 promoter | CTD | PMID:22457795 | cadmium dichloride | multiple interactions | ISO | ACY3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ACY3 mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon results in decreased expression of ACY3 mRNA | CTD | PMID:25620056 | clofibric acid | affects expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Clofibric Acid affects the expression of ACY3 mRNA | CTD | PMID:17602206 | cobalt dichloride | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of ACY3 mRNA | CTD | PMID:24386269 | cocaine | affects expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Cocaine affects the expression of ACY3 mRNA | CTD | PMID:20187946 | cyclosporin A | decreases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ACY3 mRNA | CTD | PMID:20106945 | diethyl maleate | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | diethyl maleate results in decreased expression of ACY3 mRNA | CTD | PMID:21161181 | endosulfan | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of ACY3 mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of ACY3 mRNA | CTD | PMID:35436446 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of ACY3 mRNA | CTD | PMID:34813904 | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of ACY3 mRNA | CTD | PMID:28329830 | flutamide | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of ACY3 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACY3 mRNA | CTD | PMID:22206623 | gentamycin | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of ACY3 mRNA | CTD | PMID:33387578 | methapyrilene | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of ACY3 mRNA | CTD | PMID:30467583 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of ACY3 mRNA | CTD | PMID:34813904 | N-nitrosodiethylamine | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in decreased expression of ACY3 mRNA | CTD | PMID:19638242 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ACY3 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of ACY3 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ACY3 mRNA | CTD | PMID:26690555 and PMID:29067470 | pirinixic acid | multiple interactions | ISO | ACY3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ACY3 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ACY3 mRNA | CTD | PMID:18445702 and PMID:23811191 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ACY3 mRNA | CTD | PMID:28903501 | resveratrol | multiple interactions | ISO | ACY3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of ACY3 mRNA | CTD | PMID:23557933 | rotenone | increases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of ACY3 mRNA | CTD | PMID:28374803 | silicon dioxide | decreases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ACY3 mRNA | CTD | PMID:25895662 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of ACY3 mRNA | CTD | PMID:23221170 | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of ACY3 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of ACY3 mRNA | CTD | PMID:27131904 | sotorasib | multiple interactions | ISO | ACY3 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACY3 mRNA | CTD | PMID:36139627 | succimer | multiple interactions | EXP | | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ACY3 mRNA | CTD | PMID:26378955 | tert-butyl hydroperoxide | increases expression | EXP | | 6480464 | tert-Butylhydroperoxide results in increased expression of ACY3 mRNA | CTD | PMID:15003993 | tetrachloromethane | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of ACY3 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ACY3 mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | ISO | Acy3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ACY3 mRNA] | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ACY3 mRNA | CTD | PMID:23411599 and PMID:34492290 | trametinib | multiple interactions | ISO | ACY3 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of ACY3 mRNA | CTD | PMID:36139627 | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of ACY3 mRNA | CTD | PMID:19042947 | triphenyl phosphate | affects expression | ISO | Acy3 (Rattus norvegicus) | 6480464 | triphenyl phosphate affects the expression of ACY3 mRNA | CTD | PMID:30589522 | urethane | decreases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of ACY3 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | ACY3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ACY3 mRNA | CTD | PMID:29154799 | valproic acid | increases methylation | ISO | ACY3 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ACY3 gene | CTD | PMID:29154799 | vancomycin | increases expression | EXP | | 6480464 | Vancomycin results in increased expression of ACY3 mRNA | CTD | PMID:18930951 | |