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Gene: Gbx2 (gastrulation brain homeobox 2) Mus musculus
Symbol: Gbx2
Name: gastrulation brain homeobox 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and RNA polymerase II transcription factor binding activity. Involved in several processes, including branching involved in blood vessel morphogenesis; nervous system development; and neural crest cell migration. Localizes to the nucleus. Is expressed in several structures, including 1st branchial arch; central nervous system; ear; embryo ectoderm; and reproductive system. Orthologous to human GBX2 (gastrulation brain homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetaldehyde; acetic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D130058E05Rik; gastrulation and brain-specific homeobox protein 2; Gbx-2; homeobox protein GBX-2; MMoxA; stimulated by retinoic acid gene 7 protein; Stra7
Homo sapiens (human) : GBX2 (gastrulation brain homeobox 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gbx2 (gastrulation brain homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gbx2 (gastrulation brain homeobox 2)
Canis lupus familiaris (dog) : GBX2 (gastrulation brain homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gbx2 (gastrulation brain homeobox 2)
Sus scrofa (pig) : GBX2 (gastrulation brain homeobox 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl189,927,956 - 89,931,179 (-)Ensembl
GRCm38189,927,962 - 89,931,176 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37191,824,537 - 91,827,751 (-)NCBIGRCm37mm9NCBIm37
MGSCv36191,759,133 - 91,762,347 (-)NCBImm8
Celera192,869,152 - 92,872,368 (-)NCBICelera
Cytogenetic Map1 DNCBI
cM Map145.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gbx2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553014
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.