Gbx2 (gastrulation brain homeobox 2) - Rat Genome Database

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Gene: Gbx2 (gastrulation brain homeobox 2) Mus musculus
Analyze
Symbol: Gbx2
Name: gastrulation brain homeobox 2
RGD ID: 1553014
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within several processes, including branching involved in blood vessel morphogenesis; nervous system development; and neural crest cell migration. Located in nucleus. Is expressed in several structures, including 1st branchial arch; central nervous system; ear; embryo ectoderm; and reproductive system. Orthologous to human GBX2 (gastrulation brain homeobox 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D130058E05Rik; gastrulation and brain-specific homeobox protein 2; Gbx-2; homeobox protein GBX-2; MMo; MMoxA; St; stimulated by retinoic acid gene 7 protein; Stra7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39189,855,684 - 89,858,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl189,855,678 - 89,858,901 (-)EnsemblGRCm39 Ensembl
GRCm38189,927,962 - 89,931,176 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl189,927,956 - 89,931,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv37191,824,537 - 91,827,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36191,759,133 - 91,762,347 (-)NCBIMGSCv36mm8
Celera192,869,152 - 92,872,368 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map145.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (TAS)
nucleus  (IBA,IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aortic arch morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal choroid plexus morphology  (IAGP)
abnormal cochlear ganglion morphology  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal crista ampullaris morphology  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal forebrain development  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal head development  (IAGP)
abnormal heart morphology  (IAGP)
abnormal hindbrain development  (IAGP)
abnormal hindbrain morphology  (IAGP)
abnormal inferior colliculus morphology  (IAGP)
abnormal inner ear morphology  (IAGP)
abnormal innervation  (IAGP)
abnormal locus ceruleus morphology  (IAGP)
abnormal membranous labyrinth morphology  (IAGP)
abnormal metencephalon morphology  (IAGP)
abnormal midbrain development  (IAGP)
abnormal midbrain morphology  (IAGP)
abnormal midbrain-hindbrain boundary development  (IAGP)
abnormal midbrain-hindbrain boundary morphology  (IAGP)
abnormal motor neuron morphology  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neural crest cell morphology  (IAGP)
abnormal neural plate morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal organ of Corti morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pons morphology  (IAGP)
abnormal postnatal growth  (IAGP)
abnormal rhombomere 5 morphology  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal styloid process morphology  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal thalamus morphology  (IAGP)
abnormal thymus development  (IAGP)
abnormal trigeminal ganglion morphology  (IAGP)
abnormal vascular endothelial cell differentiation  (IAGP)
abnormal vestibular saccular macula morphology  (IAGP)
absent cerebellum  (IAGP)
absent cochlear ganglion  (IAGP)
absent common crus  (IAGP)
absent embryonic telencephalon  (IAGP)
absent endolymphatic duct  (IAGP)
absent lateral semicircular canal  (IAGP)
absent midbrain-hindbrain boundary  (IAGP)
absent nasal placodes  (IAGP)
absent optic placodes  (IAGP)
absent optic vesicle  (IAGP)
absent pharyngeal arches  (IAGP)
absent posterior semicircular canal  (IAGP)
absent scala media  (IAGP)
absent superior semicircular canal  (IAGP)
absent supraoccipital bone  (IAGP)
absent trigeminal nerve  (IAGP)
absent vestibular saccule  (IAGP)
cerebellum vermis hypoplasia  (IAGP)
cleft palate  (IAGP)
cyanosis  (IAGP)
decreased body weight  (IAGP)
decreased cochlea coiling  (IAGP)
decreased embryo size  (IAGP)
decreased embryonic neuroepithelial cell proliferation  (IAGP)
decreased embryonic neuroepithelium thickness  (IAGP)
decreased neural crest cell number  (IAGP)
dilated heart  (IAGP)
double outlet right ventricle  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
exencephaly  (IAGP)
fusion of glossopharyngeal and vagus nerve  (IAGP)
fusion of middle ear ossicles  (IAGP)
increased inferior colliculus size  (IAGP)
inner ear cyst  (IAGP)
interrupted aortic arch, type b  (IAGP)
middle ear ossicle hypoplasia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
otic capsule hypoplasia  (IAGP)
overriding aortic valve  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
retroesophageal right subclavian artery  (IAGP)
right aortic arch  (IAGP)
small ears  (IAGP)
small mandible  (IAGP)
small otic vesicle  (IAGP)
styloid process hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1720547   PMID:7649373   PMID:7687285   PMID:7758585   PMID:8601031   PMID:8838315   PMID:9022055   PMID:9232602   PMID:9247335   PMID:9342056   PMID:9389446   PMID:9417909  
PMID:9486536   PMID:9521907   PMID:9570771   PMID:9700206   PMID:9811592   PMID:10021340   PMID:10349636   PMID:10354469   PMID:10421635   PMID:10436162   PMID:10490024   PMID:10518499  
PMID:10727869   PMID:10764649   PMID:10887078   PMID:11042159   PMID:11076861   PMID:11124114   PMID:11217851   PMID:11290295   PMID:11306624   PMID:11412024   PMID:11493561   PMID:11500373  
PMID:11532921   PMID:11704761   PMID:11731459   PMID:11731460   PMID:11748135   PMID:11820816   PMID:11863370   PMID:11900984   PMID:11967891   PMID:12118102   PMID:12194867   PMID:12231626  
PMID:12367504   PMID:12421703   PMID:12466851   PMID:12477932   PMID:12682014   PMID:12736208   PMID:12799077   PMID:12810586   PMID:12855770   PMID:12874124   PMID:12895419   PMID:12915318  
PMID:14568100   PMID:14597661   PMID:14643680   PMID:14651936   PMID:14681479   PMID:14745958   PMID:15105370   PMID:15121182   PMID:15142971   PMID:15163631   PMID:15201223   PMID:15207855  
PMID:15217369   PMID:15242798   PMID:15294144   PMID:15342729   PMID:15483110   PMID:15580630   PMID:15618518   PMID:15652707   PMID:15729686   PMID:15741321   PMID:15745951   PMID:15761950  
PMID:15782199   PMID:15790971   PMID:15829521   PMID:15857914   PMID:15917450   PMID:15961523   PMID:15996652   PMID:16109395   PMID:16141072   PMID:16141073   PMID:16166377   PMID:16325169  
PMID:16339193   PMID:16452098   PMID:16481355   PMID:16530751   PMID:16537572   PMID:16571633   PMID:16602821   PMID:16651541   PMID:16678814   PMID:16728479   PMID:16806848   PMID:16847871  
PMID:16900517   PMID:16971467   PMID:17060451   PMID:17150206   PMID:17151600   PMID:17166916   PMID:17241623   PMID:17366625   PMID:17450135   PMID:17493606   PMID:17507393   PMID:17537797  
PMID:17687036   PMID:17729296   PMID:17855431   PMID:17980036   PMID:18094027   PMID:18216176   PMID:18241853   PMID:18304314   PMID:18429041   PMID:18479186   PMID:18480159   PMID:18495817  
PMID:18694563   PMID:18697905   PMID:18794329   PMID:18799476   PMID:18799693   PMID:18929642   PMID:18930042   PMID:19020049   PMID:19030180   PMID:19122665   PMID:19244520   PMID:19279136  
PMID:19357274   PMID:19386638   PMID:19474326   PMID:19540218   PMID:19603509   PMID:19615442   PMID:19700621   PMID:19793884   PMID:19846726   PMID:19855134   PMID:19913004   PMID:19968985  
PMID:20059953   PMID:20206242   PMID:20412781   PMID:20457670   PMID:20532162   PMID:20702562   PMID:20816794   PMID:20826531   PMID:20932939   PMID:20943929   PMID:21048141   PMID:21177346  
PMID:21192082   PMID:21205797   PMID:21246658   PMID:21266408   PMID:21360792   PMID:21625468   PMID:21677750   PMID:21693512   PMID:21698205   PMID:21731673   PMID:21831920   PMID:21873635  
PMID:21925158   PMID:21925604   PMID:21930923   PMID:22007134   PMID:22102609   PMID:22182523   PMID:22371696   PMID:22457488   PMID:22566684   PMID:22627282   PMID:22705977   PMID:22718343  
PMID:22745311   PMID:22821687   PMID:22920256   PMID:22991444   PMID:22992956   PMID:22993445   PMID:23041116   PMID:23056596   PMID:23136391   PMID:23144817   PMID:23312518   PMID:23345404  
PMID:23400959   PMID:23444360   PMID:23536097   PMID:23623550   PMID:23658181   PMID:23664552   PMID:24014668   PMID:24146773   PMID:24157949   PMID:24335253   PMID:24368733   PMID:24528677  
PMID:24560577   PMID:24583262   PMID:24705356   PMID:24952961   PMID:25176648   PMID:25178196   PMID:25197075   PMID:25366972   PMID:25592224   PMID:25631876   PMID:25977363   PMID:26189100  
PMID:26212322   PMID:26297811   PMID:26400936   PMID:26490861   PMID:26534985   PMID:26577899   PMID:26718003   PMID:26879466   PMID:27100196   PMID:27302397   PMID:27349434   PMID:27384060  
PMID:27416760   PMID:27578777   PMID:27600842   PMID:27655933   PMID:27657450   PMID:27760115   PMID:27770010   PMID:27793834   PMID:27847324   PMID:27889578   PMID:27935475   PMID:28155854  
PMID:28165338   PMID:28219675   PMID:28467430   PMID:28489004   PMID:28538174   PMID:28663494   PMID:28694260   PMID:28839193   PMID:28848051   PMID:28893947   PMID:29732603   PMID:30377227  
PMID:30470704   PMID:30470893   PMID:30504125   PMID:30581079   PMID:30687002   PMID:30692221   PMID:30735127   PMID:30868103   PMID:30872278   PMID:31048552   PMID:31340933   PMID:31444215  
PMID:31872525   PMID:32244588   PMID:32466118   PMID:32553121   PMID:32675279   PMID:32703236   PMID:32792512   PMID:33207201   PMID:33322598   PMID:33328221   PMID:33469032   PMID:33711282  
PMID:33795231   PMID:33821423   PMID:33827819   PMID:33851097   PMID:34292881   PMID:34851821   PMID:35027568   PMID:35377797   PMID:35417707   PMID:35590075   PMID:35690356   PMID:35793630  
PMID:36476860   PMID:36819097   PMID:37017267  


Genomics

Comparative Map Data
Gbx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39189,855,684 - 89,858,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl189,855,678 - 89,858,901 (-)EnsemblGRCm39 Ensembl
GRCm38189,927,962 - 89,931,176 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl189,927,956 - 89,931,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv37191,824,537 - 91,827,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36191,759,133 - 91,762,347 (-)NCBIMGSCv36mm8
Celera192,869,152 - 92,872,368 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map145.06NCBI
GBX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382236,161,340 - 236,168,386 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2236,165,236 - 236,168,386 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,073,879 - 237,077,029 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,739,046 - 236,741,391 (-)NCBINCBI36Build 36hg18NCBI36
Build 342236,856,306 - 236,858,652NCBI
Celera2230,787,441 - 230,789,786 (-)NCBICelera
Cytogenetic Map2q37.2NCBI
HuRef2228,868,880 - 228,871,225 (-)NCBIHuRef
CHM1_12237,080,112 - 237,082,457 (-)NCBICHM1_1
T2T-CHM13v2.02236,651,067 - 236,658,113 (-)NCBIT2T-CHM13v2.0
Gbx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8997,957,304 - 97,959,883 (-)NCBIGRCr8
mRatBN7.2990,509,633 - 90,512,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl990,509,633 - 90,512,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx998,936,286 - 98,938,865 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09104,072,186 - 104,074,765 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09102,437,722 - 102,440,301 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0997,063,265 - 97,065,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl997,063,728 - 97,065,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0996,754,122 - 96,756,543 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4989,034,340 - 89,037,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1989,239,950 - 89,240,065 (-)NCBI
Celera988,058,118 - 88,060,697 (-)NCBICelera
Cytogenetic Map9q36NCBI
Gbx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955453538,280 - 540,306 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955453538,066 - 541,415 (+)NCBIChiLan1.0ChiLan1.0
GBX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213138,794,032 - 138,798,437 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B138,808,996 - 138,813,401 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B123,392,499 - 123,399,549 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GBX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12547,005,509 - 47,008,367 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2547,005,504 - 47,008,512 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2547,508,245 - 47,511,037 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02547,359,565 - 47,362,361 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2547,359,543 - 47,362,930 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12547,267,592 - 47,270,382 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02547,061,156 - 47,063,938 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02547,291,077 - 47,293,871 (-)NCBIUU_Cfam_GSD_1.0
Gbx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303189,066,154 - 189,069,657 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365251,870,195 - 1,873,539 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365251,870,211 - 1,873,536 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GBX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,029,070 - 136,032,316 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,029,393 - 136,032,568 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215150,464,293 - 150,466,933 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GBX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110122,177,725 - 122,184,448 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10122,182,301 - 122,184,446 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604077,219,450 - 77,225,155 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gbx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248471,879,007 - 1,881,669 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248471,878,946 - 1,881,794 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gbx2
111 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:741
Count of miRNA genes:444
Interacting mature miRNAs:502
Transcripts:ENSMUST00000036954
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15854919192549443Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15854919192549443Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15672692290727077Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170133533104139557Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1300821Lore1_mloss of righting induced by ethanol 1 (mouse)Not determined17554919192941077Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15672692290727077Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15799197791992080Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15799197791992080Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15626621490266360Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15597494889975057Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89786512123786512Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15799197791992080Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173615692107615830Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173266214108838414Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177123115110536075Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179858683113858791Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73615692107615830Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182832635116832635Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15626621490266360Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180245593126386517Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186483929120483929Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179858683113858791Mouse
11667074Led2_mlate embryonic death 2 (mouse)185696027117195081Mouse
14696693Avd2q1_mattack value day 2 QTL 1 (mouse)17897771790927722Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182832635116832635Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
14747009Manh49_mmandible shape 49 (mouse)15794135191941351Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189786512123786512Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17747663795827725Mouse

Markers in Region
L39770  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38189,928,294 - 89,928,485UniSTSGRCm38
MGSCv37191,824,869 - 91,825,060UniSTSGRCm37
Celera192,869,484 - 92,869,675UniSTS
Cytogenetic Map1C5-E1UniSTS
Whitehead_YAC1 UniSTS
U74300  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38189,928,171 - 89,928,278UniSTSGRCm38
MGSCv37191,824,746 - 91,824,853UniSTSGRCm37
Celera192,869,361 - 92,869,468UniSTS
Cytogenetic Map1C5-E1UniSTS
Whitehead/MRC_RH11298.27UniSTS
Gbx2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38189,928,043 - 89,928,670UniSTSGRCm38
MGSCv37191,824,618 - 91,825,245UniSTSGRCm37
Celera192,869,233 - 92,869,860UniSTS
Cytogenetic Map1C5-E1UniSTS
cM Map165.0UniSTS
fd52b08.x1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38189,929,425 - 89,929,952UniSTSGRCm38
GRCm38189,929,425 - 89,929,944UniSTSGRCm38
MGSCv37191,826,000 - 91,826,527UniSTSGRCm37
MGSCv37191,826,000 - 91,826,519UniSTSGRCm37
Celera192,870,615 - 92,871,140UniSTS
Celera192,870,615 - 92,871,144UniSTS
Cytogenetic Map1C5-E1UniSTS
Gbx2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C5-E1UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000036954   ⟹   ENSMUSP00000048508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl189,855,678 - 89,858,901 (-)Ensembl
GRCm38.p6 Ensembl189,927,956 - 89,931,179 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187633
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl189,855,688 - 89,856,907 (-)Ensembl
GRCm38.p6 Ensembl189,927,966 - 89,929,185 (-)Ensembl
RefSeq Acc Id: NM_010262   ⟹   NP_034392
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39189,855,684 - 89,858,898 (-)NCBI
GRCm38189,927,962 - 89,931,176 (-)ENTREZGENE
MGSCv37191,824,537 - 91,827,751 (-)RGD
Celera192,869,152 - 92,872,368 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034392   ⟸   NM_010262
- UniProtKB: Q14A66 (UniProtKB/Swiss-Prot),   P48031 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000048508   ⟸   ENSMUST00000036954
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48031-F1-model_v2 AlphaFold P48031 1-348 view protein structure

Promoters
RGD ID:15092163
Promoter ID:EPDNEWNC_M69
Type:single initiation site
Name:D130058E05Rik_1
Description:RIKEN cDNA D130058E05 gene [Source:MGISymbol;Acc:MGI:2444614]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38189,930,231 - 89,930,291EPDNEWNC
RGD ID:6874446
Promoter ID:EPDNEW_M674
Type:initiation region
Name:Gbx2_1
Description:Mus musculus gastrulation brain homeobox 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38189,931,188 - 89,931,248EPDNEW
RGD ID:6817748
Promoter ID:MM_KWN:1588
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   ES_Cell,   Lung
Transcripts:AK051578_D130058E05RIK,   NM_010262
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36191,827,601 - 91,830,162 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95668 AgrOrtholog
Ensembl Genes ENSMUSG00000034486 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000036954 ENTREZGENE
  ENSMUST00000036954.9 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GBX-1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14472 UniProtKB/Swiss-Prot
MGD MGI:95668 ENTREZGENE
NCBI Gene 14472 ENTREZGENE
PANTHER PTHR24334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24334:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gbx2 PhenoGen
PRINTS HOMEOBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GBX2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q14A66 ENTREZGENE
  Q3URA0_MOUSE UniProtKB/TrEMBL
  Q3UUJ3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q14A66 UniProtKB/Swiss-Prot