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Gene: Gbx2 (gastrulation brain homeobox 2) Mus musculus
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Symbol: Gbx2
Name: gastrulation brain homeobox 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and RNA polymerase II transcription factor binding activity. Involved in several processes, including branching involved in blood vessel morphogenesis; nervous system development; and neural crest cell migration. Localizes to the nucleus. Is expressed in several structures, including 1st branchial arch; central nervous system; ear; embryo ectoderm; and reproductive system. Orthologous to human GBX2 (gastrulation brain homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetaldehyde; acetic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D130058E05Rik; gastrulation and brain-specific homeobox protein 2; Gbx-2; homeobox protein GBX-2; MMoxA; stimulated by retinoic acid gene 7 protein; Stra7
Orthologs:
Homo sapiens (human) : GBX2 (gastrulation brain homeobox 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gbx2 (gastrulation brain homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gbx2 (gastrulation brain homeobox 2)
Canis lupus familiaris (dog) : GBX2 (gastrulation brain homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gbx2 (gastrulation brain homeobox 2)
Sus scrofa (pig) : GBX2 (gastrulation brain homeobox 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl189,927,956 - 89,931,179 (-)Ensembl
GRCm38189,927,962 - 89,931,176 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37191,824,537 - 91,827,751 (-)NCBIGRCm37mm9NCBIm37
MGSCv36191,759,133 - 91,762,347 (-)NCBImm8
Celera192,869,152 - 92,872,368 (-)NCBICelera
Cytogenetic Map1 DNCBI
cM Map145.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gbx2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553014
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.