Trim31 (tripartite motif-containing 31) - Rat Genome Database

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Gene: Trim31 (tripartite motif-containing 31) Mus musculus
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Symbol: Trim31
Name: tripartite motif-containing 31
RGD ID: 1553005
MGI Page MGI
Description: Predicted to enable transcription coactivator activity and ubiquitin protein ligase activity. Involved in innate immune response and negative regulation of viral entry into host cell. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Is expressed in Peyer's patch; gut; and testis. Orthologous to human TRIM31 (tripartite motif containing 31); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BC026666; E3 ubiquitin-protein ligase TRIM31; HCG1; HCGI; MGC37625; RING-type E3 ubiquitin transferase TRIM31; RNF; tripartite motif-containing protein 31
RGD Orthologs
Human
Rat
Bonobo
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,209,022 - 37,221,109 (+)NCBIGRCm39mm39
GRCm39 Ensembl1737,209,010 - 37,221,106 (+)Ensembl
GRCm381736,898,130 - 36,910,217 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,898,118 - 36,910,214 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,035,075 - 37,047,162 (+)NCBIGRCm37mm9NCBIm37
MGSCv361736,506,183 - 36,518,270 (+)NCBImm8
Celera1740,317,255 - 40,329,416 (+)NCBICelera
Cytogenetic Map17B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IEA)

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18248090   PMID:19665990   PMID:21267068   PMID:21873635   PMID:24194600  
PMID:27929086   PMID:27992402   PMID:31149635  


Genomics

Comparative Map Data
Trim31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,209,022 - 37,221,109 (+)NCBIGRCm39mm39
GRCm39 Ensembl1737,209,010 - 37,221,106 (+)Ensembl
GRCm381736,898,130 - 36,910,217 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,898,118 - 36,910,214 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,035,075 - 37,047,162 (+)NCBIGRCm37mm9NCBIm37
MGSCv361736,506,183 - 36,518,270 (+)NCBImm8
Celera1740,317,255 - 40,329,416 (+)NCBICelera
Cytogenetic Map17B1NCBI
TRIM31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl630,102,897 - 30,113,090 (-)EnsemblGRCh38hg38GRCh38
GRCh38630,102,892 - 30,113,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37630,070,674 - 30,080,867 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,178,653 - 30,188,846 (-)NCBINCBI36hg18NCBI36
Build 34630,178,654 - 30,188,833NCBI
Celera631,668,926 - 31,679,124 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,868,836 - 29,879,034 (-)NCBIHuRef
CHM1_1630,072,756 - 30,082,946 (-)NCBICHM1_1
Trim31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2201,653,165 - 1,666,494 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl202,146,257 - 2,159,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0202,146,245 - 2,159,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0204,183,577 - 4,196,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,745,437 - 1,758,194 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,746,131 - 1,757,962 (-)NCBI
Celera202,361,720 - 2,375,040 (-)NCBICelera
Cytogenetic Map20p12NCBI
TRIM31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1630,550,802 - 30,560,993 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,550,802 - 30,560,977 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0629,880,668 - 29,890,905 (-)NCBIMhudiblu_PPA_v0panPan3
Trim31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,646,388 - 32,657,283 (-)NCBI
SpeTri2.0NW_004936723934,808 - 945,279 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1722,665,150 - 22,681,616 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,946,635 - 24,960,048 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172628636340794146Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172749681845311728Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172765914543574223Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172831148062311728Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined172982162963821740Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3072257564722705Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3076892947728778Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173184267837333884Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173290000053800000Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173495684169858931Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173565926669659396Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173648271570482715Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:761
Count of miRNA genes:447
Interacting mature miRNAs:521
Transcripts:ENSMUST00000078438
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000078438   ⟹   ENSMUSP00000077535
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1736,898,118 - 36,910,214 (+)Ensembl
RefSeq Acc Id: NM_146077   ⟹   NP_666189
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391737,209,022 - 37,221,109 (+)NCBI
GRCm381736,898,130 - 36,910,217 (+)ENTREZGENE
MGSCv371737,035,075 - 37,047,162 (+)RGD
Celera1740,317,255 - 40,329,416 (+)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_666189 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH26666 (Get FASTA)   NCBI Sequence Viewer  
  BAC28407 (Get FASTA)   NCBI Sequence Viewer  
  EDL23309 (Get FASTA)   NCBI Sequence Viewer  
  Q8R0K2 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_666189   ⟸   NM_146077
- UniProtKB: Q8R0K2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000077535   ⟸   ENSMUST00000078438
Protein Domains
B30.2/SPRY

Promoters
RGD ID:13676016
Promoter ID:EPDNEW_M22157
Type:multiple initiation site
Name:Trim31_1
Description:Mus musculus tripartite motif-containing 31 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381736,898,118 - 36,898,178EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2385051 AgrOrtholog
Ensembl Genes ENSMUSG00000058063 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000077535 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000078438 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro B30.2/SPRY UniProtKB/Swiss-Prot
  B30.2/SPRY_sf UniProtKB/Swiss-Prot
  Butyrophylin_SPRY UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  SPRY_dom UniProtKB/Swiss-Prot
  Znf_B-box UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report mmu:224762 UniProtKB/Swiss-Prot
MGD MGI:2385051 ENTREZGENE
NCBI Gene 224762 ENTREZGENE
Pfam SPRY UniProtKB/Swiss-Prot
  zf-B_box UniProtKB/Swiss-Prot
PhenoGen Trim31 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot
PROSITE B302_SPRY UniProtKB/Swiss-Prot
  ZF_BBOX UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
SMART BBOX UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot
  SPRY UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt Q8R0K2 ENTREZGENE, UniProtKB/Swiss-Prot