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Gene: Impdh2 (inosine monophosphate dehydrogenase 2) Mus musculus
Symbol: Impdh2
Name: inosine monophosphate dehydrogenase 2
Description: ENCODES a protein that exhibits IMP dehydrogenase activity; nucleotide binding (ortholog); INVOLVED IN cellular response to interleukin-4; lymphocyte proliferation; purine nucleotide biosynthetic process; PARTICIPATES IN de novo purine biosynthetic pathway; mycophenolic acid pharmacokinetics pathway; purine metabolic pathway; ASSOCIATED WITH abnormal cytotoxic T cell physiology; abnormal immune system cell morphology; abnormal lymphocyte cell number; ASSOCIATED WITH Animal Disease Models (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; carbon nanotube
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IMP dehydrogenase 2; IMP dehydrogenase type II; IMPD; IMPD 2; IMPDH 2; IMPDH-II; inosine 5'-phosphate dehydrogenase 2; inosine-5'-monophosphate dehydrogenase 2
Homo sapiens (human) : IMPDH2 (inosine monophosphate dehydrogenase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Impdh2 (inosine monophosphate dehydrogenase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Impdh2 (inosine monophosphate dehydrogenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IMPDH2 (inosine monophosphate dehydrogenase 2)
Canis lupus familiaris (dog) : IMPDH2 (inosine monophosphate dehydrogenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Impdh2 (inosine monophosphate dehydrogenase 2)
Sus scrofa (pig) : IMPDH2 (inosine monophosphate dehydrogenase 2)
more info ...
Related Pseudogenes: Impdh2-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389108,560,291 - 108,565,584 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,462,832 - 108,467,904 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,418,604 - 108,423,676 (+)NCBImm8
Celera9108,171,703 - 108,176,814 (+)NCBICelera
Cytogenetic Map9 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Impdh2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552951
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.