Pelo (pelota mRNA surveillance and ribosome rescue factor)

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Gene: Pelo (pelota mRNA surveillance and ribosome rescue factor) Mus musculus

Analyze

Symbol:

Pelo

Name:

pelota mRNA surveillance and ribosome rescue factor

RGD ID:

1552813

MGI Page

MGI

Description:

Predicted to have endonuclease activity and metal ion binding activity. Involved in several processes, including inner cell mass cell proliferation; mesenchymal to epithelial transition; and positive regulation of BMP signaling pathway. Predicted to localize to cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; limb muscle; orbito-sphenoid; and spleen. Orthologous to human PELO (pelota mRNA surveillance and ribosome rescue factor); PARTICIPATES IN translation termination pathway; mRNA decay pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

AA409897; AI852218; pelota homolog; pelota homolog (Drosophila); protein pelota homolog

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	115,224,891 - 115,226,694 (-)	NCBI	GRCm39		mm39
GRCm38	13	115,088,355 - 115,090,158 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	115,088,355 - 115,090,186 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	115,878,563 - 115,880,366 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	13	116,209,242 - 116,211,703 (-)	NCBI			mm8
Celera	13	119,447,710 - 119,449,318 (-)	NCBI		Celera
Cytogenetic Map	13	D2.2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

(S)-colchicine (ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dinitrotoluene (ISO)

adenine (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

arsane (EXP)

arsenic atom (EXP)

benzene (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[e]pyrene (ISO)

beta-naphthoflavone (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (EXP)

chromium(6+) (EXP)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethanol (EXP)

ethyl methanesulfonate (ISO)

etoposide (ISO)

flutamide (ISO)

folic acid (EXP)

formaldehyde (ISO)

hydroxyurea (ISO)

lead(0) (ISO)

lead(2+) (ISO)

mercury dibromide (ISO)

methapyrilene (ISO)

mitomycin C (ISO)

nefazodone (ISO)

nickel atom (ISO)

nickel dichloride (ISO)

nickel sulfate (ISO)

nimesulide (ISO)

oxaliplatin (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (EXP)

pentachlorophenol (EXP)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

progesterone (ISO)

quercetin (ISO)

SB 431542 (ISO)

sodium dichromate (ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (EXP)

topotecan (ISO)

trichostatin A (ISO)

urethane (ISO)

valdecoxib (ISO)

valproic acid (EXP,ISO)

vincaleukoblastine (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

chromosome organization (IMP)

endoderm development (IDA,IMP)

inner cell mass cell proliferation (IMP)

mesenchymal to epithelial transition (IMP)

nonfunctional rRNA decay (IBA)

nuclear-transcribed mRNA catabolic process, no-go decay (IBA)

nuclear-transcribed mRNA catabolic process, non-stop decay (IEA)

positive regulation of BMP signaling pathway (IMP)

ribosome disassembly (IBA)

RNA surveillance (IEA)

stem cell population maintenance (IMP)

Cellular Component

cytoplasm (IBA,TAS)

nucleus (IEA)

Molecular Function

endonuclease activity (IEA)

hydrolase activity (IEA)

metal ion binding (IEA)

nuclease activity (IEA)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mRNA decay pathway (IEA)

translation termination pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal extraembryonic endoderm formation (IAGP)

abnormal extraembryonic tissue morphology (IAGP)

abnormal germ layer development (IAGP)

absent extraembryonic coelom (IAGP)

absent inner cell mass proliferation (IAGP)

aneuploidy (IAGP)

decreased embryo size (IAGP)

embryonic growth arrest (IAGP)

embryonic growth retardation (IAGP)

embryonic lethality between implantation and somite formation, complete penetrance (IAGP)

embryonic lethality, complete penetrance (IAGP)

no abnormal phenotype detected (IAGP)

polyploidy (IAGP)

References

References - curated


1.	Adham IM, etal., Mol Cell Biol 2003 Feb;23(4):1470-6.
2.	Franckenberg S, etal., Curr Opin Struct Biol. 2012 Dec;22(6):786-96. doi: 10.1016/j.sbi.2012.08.002. Epub 2012 Sep 29.
3.	MGD data from the GO Consortium
4.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	Pipeline to import KEGG annotations from KEGG into RGD
6.	RGD automated import pipeline
7.	RGD automated import pipeline for gene-chemical interactions
8.	Shamsadin R, etal., Cytogenet Genome Res 2002;97(1-2):95-9.

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12477932	PMID:15489334	PMID:15782199	PMID:16141072	PMID:16141073	PMID:16919269
PMID:17093407	PMID:18287559	PMID:21267068	PMID:21873635	PMID:21905163	PMID:24835669	PMID:25061210	PMID:25661254	PMID:26410627	PMID:27164299	PMID:29643507	PMID:30707697
PMID:32098917	PMID:32325033	PMID:32968282

Genomics

Comparative Map Data

Pelo
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	115,224,891 - 115,226,694 (-)	NCBI	GRCm39		mm39
GRCm38	13	115,088,355 - 115,090,158 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	115,088,355 - 115,090,186 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	115,878,563 - 115,880,366 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	13	116,209,242 - 116,211,703 (-)	NCBI			mm8
Celera	13	119,447,710 - 119,449,318 (-)	NCBI		Celera
Cytogenetic Map	13	D2.2	NCBI

PELO
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	5	52,787,916 - 52,804,044 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	5	52,787,916 - 52,804,044 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	5	52,083,750 - 52,099,878 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	5	52,083,774 - 52,098,451 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	52,119,531 - 52,134,208 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	5	52,119,530 - 52,134,206	NCBI
Celera	5	49,037,324 - 49,052,004 (+)	NCBI
Cytogenetic Map	5	q11.2	NCBI
HuRef	5	49,055,620 - 49,070,302 (+)	NCBI		HuRef
CHM1_1	5	52,086,424 - 52,101,104 (+)	NCBI		CHM1_1

Pelo
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	46,797,853 - 46,799,621 (-)	NCBI
Rnor_6.0 Ensembl	2	47,266,738 - 47,268,625 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	2	47,266,758 - 47,268,526 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	2	71,808,491 - 71,810,259 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	45,900,723 - 45,902,491 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	2	45,828,956 - 45,830,724 (-)	NCBI
Celera	2	42,545,596 - 42,547,364 (-)	NCBI		Celera
Cytogenetic Map	2	q14	NCBI

Pelo
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	14,564,366 - 14,566,178 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955446	14,564,366 - 14,566,178 (-)	NCBI	ChiLan1.0	ChiLan1.0

PELO
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	5	62,851,499 - 62,865,786 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	62,851,099 - 62,865,786 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	5	61,229,841 - 61,247,565 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

PELO
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	62,440,923 - 62,443,598 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Pelo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936480	14,578,718 - 14,580,690 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PELO
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	32,142,034 - 32,148,335 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	32,130,254 - 32,146,114 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	33,953,117 - 33,955,102 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PELO
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	49,094,330 - 49,097,545 (+)	NCBI
ChlSab1.1 Ensembl	4	49,094,528 - 49,100,838 (+)	Ensembl

Pelo
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624759	6,525,529 - 6,527,320 (-)	NCBI

Position Markers

RH124904

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	13	115,088,459 - 115,088,658	UniSTS	GRCm38
MGSCv37	13	115,878,667 - 115,878,866	UniSTS	GRCm37
Celera	13	119,447,814 - 119,448,013	UniSTS
Cytogenetic Map	13	D2.2	UniSTS

PMC141158P1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	13	115,090,430 - 115,090,641	UniSTS	GRCm38
MGSCv37	13	115,880,638 - 115,880,849	UniSTS	GRCm37
Cytogenetic Map	13	D2.2	UniSTS

AI852218

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	13	115,088,564 - 115,088,687	UniSTS	GRCm38
MGSCv37	13	115,878,772 - 115,878,895	UniSTS	GRCm37
Celera	13	119,447,919 - 119,448,042	UniSTS
Cytogenetic Map	13	D2.2	UniSTS
Whitehead/MRC_RH	13	994.85	UniSTS

Pelo

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	13	D2.2	UniSTS
cM Map	13		UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558741	Ses10_m	salmonella enteritidis susceptibility 10 (mouse)			Not determined		13	82603460	116603598	Mouse
4142465	Pbwg17_m	postnatal body weight growth 17 (mouse)			Not determined		13	83739552	117739748	Mouse
14700691	Cisaq1_m	coxsackieviral infection serum ALT QTL 1 (mouse)					13	86000000	120000000	Mouse
4140995	Fbtq6_m	femoral bone trait QTL 6 (mouse)			Not determined		13	86205109	120205250	Mouse
1300939	Hrtfm6_m	heart failure modifier 6 (mouse)			Not determined		13	91247158	120421639	Mouse
1300876	Tanidd2_m	tally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)			Not determined		13	91828769	120421639	Mouse
1301142	Heal2_m	wound healing/regeneration 2 (mouse)			Not determined		13	93738733	120421639	Mouse
4142338	Skmw18_m	skeletal muscle weight 18 (mouse)			Not determined		13	94391865	120421639	Mouse
1558763	Gct9_m	granulosa cell tumorigenesis 9 (mouse)			Not determined		13	94900290	120421639	Mouse
1357468	Rplag_m	reduced platelet aggregation (mouse)			Not determined		13	95365596	120421639	Mouse
14746974	Manh75_m	mandible shape 75 (mouse)					13	99250111	120421639	Mouse
12879496	Fexq2_m	fear expression QTL 2 (mouse)					13	100604983	120421639	Mouse
4142400	Tgq24_m	triglyceride QTL 24 (mouse)			Not determined			102466094	120421639	Mouse
4141826	Tbqt5_m	tibia bone quality traits 5 (mouse)			Not determined		13	103205109	116906680	Mouse
4142334	Svtms_m	survival time modifier of Sod2 (mouse)			Not determined		13	107477080	119339836	Mouse
4141704	Hipq1_m	hyperinsulin production QTL 1 (mouse)			Not determined			110272953	119339836	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	118
Count of miRNA genes:	109
Interacting mature miRNAs:	116
Transcripts:	ENSMUST00000109226
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_134058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC175538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF148638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF148639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI854576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK077286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK168228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK170635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK206762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB767039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC050209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC057160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000109226 ⟹ ENSMUSP00000104849

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	13	115,088,355 - 115,090,186 (-)	Ensembl

RefSeq Acc Id:

NM_134058 ⟹ NP_598819

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	13	115,224,891 - 115,226,694 (-)	NCBI
GRCm38	13	115,088,355 - 115,090,158 (-)	ENTREZGENE
MGSCv37	13	115,878,563 - 115,880,366 (-)	RGD
Celera	13	119,447,710 - 119,449,318 (-)	RGD
cM Map	13		ENTREZGENE

Sequence:

show sequence

GGAAGTCCCGAGAGTTGACTCGTGCTGAGCGTGAGGTTTGCCGCGCCGCGCGTGGGCCAGCGCG
CGGAGACTTGAGAAAAAGCGTGGGGTAAAAGTGCTGTCCCGAGCTGCAAGAGTTAGAGGTAGTG
TTTCCTTCCGGGCCTGAGCCCGCCGCCCCTTCCCTGCCCCGGCCCCCCCTCCTGGGGACACCCC
CCCCCCCCCTAGCGTCCCCTGTTCTGAACTGAGCCCCTGCTGAGGTCATGAAGCTCGTGAGGAA
GGATATCGAGAAGGACAATGCGGGCCAGGTCACCCTCGTCCCCGAGGAGCCCGAGGACATGTGG
CACACCTTCAATTTAGTGCAGGTGGGCGACAGCCTGCGCGCCTCCACCATCCGCAAGGTCCAGA
CCGAGTCCTCCACAGGCAGCGTGGGGAGCAACCGTGTCCGCACCACCCTCACCCTTTGCGTGGA
GGCCATCGACTTCGACTCCCAGGCCTGCCAGCTGCGGGTGAAGGGGACCAATATCCAAGAGAAT
GAGTATGTCAAGATGGGGGCTTACCACACCATCGAACTGGAGCCCAACCGCCAGTTCACCCTGG
CCAAGAAACAGTGGGACAGTGTGGTTCTGGAACGCATCGAGCAGGCTTGCGACCCGGCGTGGAG
CGCTGATGTGGCAGCTGTGGTCATGCAGGAGGGCCTGGCCCACGTCTGCTTAGTCACGCCCAGC
ATGACCCTTACCCGGGCCAAGGTGGAGGTGAACATCCCCAGGAAACGGAAAGGCAACTGCTCCC
AGCATGACCGGGCCCTGGAGCGGTTCTATGAACAGGTGGTCCAGGCCATCCAGCGCCACATAAA
CTTCGAGGTTGTAAAGTGCGTTCTGGTGGCCAGCCCTGGATTCGTGCGAGAGCAGTTCTGCGAT
TACATGTTTCAGCAAGCTGTGAAGACGGACAATAAAGTGCTCCTGGAAAACCGCTCCAAATTCC
TTCAGGTGCACGCCTCCTCTGGACACAAGTACTCCCTGAAAGAGGCCCTCTGCGACCCTACTGT
AGCGAGCCGCCTTTCAGACACAAAGGCAGCGGGCGAAGTAAAAGCCTTGGATGACTTCTACAAA
ATGTTACAGCACGAGCCCGACCGAGCGTTCTATGGACTCAAGCAGGTGGAGAGGGCCAACGAAG
CCTTGGCCATAGACACTTTGCTCATCAGTGACGAGCTCTTCCGGCATCAGGATGTGGCCACCCG
GAGCCGGTATGTCAGGCTAGTGGACAGTGTGAAGGAGAATGCGGGCACCGTAAGGATATTCTCT
AGTCTCCATGTGTCGGGGGAACAGCTGGGCCAGCTGACGGGAGTAGCCGCCATTCTCCGCTTCC
CAGTGCCAGAACTTTCTGACCAAGAGGATGATTCAAGTTCTGAAGAGGATTAAGACTGGCAGTT
AATAGTTTCTTCCCTGGTTTTCTCAGCATCCTTGGCAGGTGCCAGAGCAGCACTTGTTGATCCT
GCTGGGGTTTCTTGTGTGTTGGGTTCACATTAAGTGTTTTATGATTTGGTGGGCAGGACATGTA
TTCAAATTAAATAAATCACGACGATGTCCAAGCTTAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_598819	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH50209	(Get FASTA)	NCBI Sequence Viewer
	AAH57160	(Get FASTA)	NCBI Sequence Viewer
	AAK58116	(Get FASTA)	NCBI Sequence Viewer
	AAK58117	(Get FASTA)	NCBI Sequence Viewer
	BAE27128	(Get FASTA)	NCBI Sequence Viewer
	BAE40181	(Get FASTA)	NCBI Sequence Viewer
	BAE41926	(Get FASTA)	NCBI Sequence Viewer
	Q80X73	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_598819 ⟸ NM_134058

- UniProtKB:

Q80X73 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MKLVRKDIEKDNAGQVTLVPEEPEDMWHTFNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTT
LTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQA
CDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQA
IQRHINFEVVKCVLVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEA
LCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRH
QDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDDSSSEE
D

hide sequence

RefSeq Acc Id:

ENSMUSP00000104849 ⟸ ENSMUST00000109226

Protein Domains

eRF1_1

Promoters

RGD ID:

8681356

Promoter ID:

EPDNEW_M18709

Type:

initiation region

Name:

Pelo_1

Description:

Mus musculus pelota mRNA surveillance and ribosome rescue factor, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M18710

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	13	115,090,179 - 115,090,239	EPDNEW

RGD ID:

6824236

Promoter ID:

MM_KWN:15328

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

UC007RYB.1, UC007RYC.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	13	115,879,706 - 115,880,617 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2145154	AgrOrtholog
Ensembl Genes	ENSMUSG00000042275	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000104849	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000109226	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	2.30.30.870	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.1330.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.420.60	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	eFR1_2_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	eRF1_1_Pelota	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	eRF1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	eRF1_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	L30e-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pelota/DOM34_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transl-rel_pelota	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:105083	UniProtKB/Swiss-Prot
MGD	MGI:2145154	ENTREZGENE
NCBI Gene	105083	ENTREZGENE
PANTHER	PTHR10853	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	eRF1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	eRF1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	eRF1_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pelo	PhenoGen
SMART	eRF1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF159065	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF55315	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs	pelota	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	PELO_MOUSE	UniProtKB/Swiss-Prot
	Q3THL5_MOUSE	UniProtKB/TrEMBL
	Q80X73	ENTREZGENE
UniProt Secondary	Q3TCN0	UniProtKB/Swiss-Prot
	Q6PG91	UniProtKB/Swiss-Prot
	Q91UZ2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-09-05	Pelo	pelota mRNA surveillance and ribosome rescue factor		pelota homolog (Drosophila)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)