Cnih2 (cornichon family AMPA receptor auxiliary protein 2)

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Gene: Cnih2 (cornichon family AMPA receptor auxiliary protein 2) Mus musculus

Analyze

Symbol:

Cnih2

Name:

cornichon family AMPA receptor auxiliary protein 2

RGD ID:

1552794

MGI Page

MGI

Description:

Predicted to enable channel regulator activity. Involved in regulation of AMPA receptor activity. Located in dendritic spine and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Orthologous to human CNIH2 (cornichon family AMPA receptor auxiliary protein 2).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

C; CNIH-2; Cnil; cornichon homolog 2; cornichon-like protein; MGC118475

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	5,142,896 - 5,148,549 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	5,142,896 - 5,148,549 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	5,092,868 - 5,098,521 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	5,092,868 - 5,098,521 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	5,092,871 - 5,098,418 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	5,092,871 - 5,098,418 (-)	NCBI		MGSCv36	mm8
Celera	19	4,962,069 - 4,967,624 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 3 (ISO)

autosomal recessive cutis laxa type IB (ISO)

Bardet-Biedl syndrome (ISO)

glycogen storage disease V (ISO)

intellectual disability (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (EXP)

6-propyl-2-thiouracil (ISO)

aldehydo-D-glucose (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

calcitriol (ISO)

cannabidiol (ISO)

Cuprizon (ISO)

cytarabine (ISO)

D-glucose (EXP)

dibutyl phthalate (ISO)

endosulfan (ISO)

folic acid (EXP)

genistein (EXP)

glucose (EXP)

paracetamol (ISO)

pirinixic acid (EXP)

propanal (ISO)

resveratrol (ISO)

sotorasib (ISO)

sulforaphane (ISO)

sunitinib (ISO)

testosterone (ISO)

thioacetamide (ISO)

trametinib (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

localization within membrane (ISO)

negative regulation of anterograde synaptic vesicle transport (ISO)

negative regulation of receptor localization to synapse (ISO)

regulation of AMPA receptor activity (IBA,IDA,ISO)

regulation of membrane potential (ISO)

regulation of NMDA receptor activity (ISO)

regulation of postsynaptic neurotransmitter receptor activity (ISO)

synaptic transmission, glutamatergic (ISO)

vesicle-mediated transport (IEA)

Cellular Component

AMPA glutamate receptor complex (ISO)

cell projection (IEA)

dendrite (IBA,IDA)

dendritic shaft (ISO)

dendritic spine (IDA)

endoplasmic reticulum (IEA)

glutamatergic synapse (ISO)

membrane (IEA)

plasma membrane (IEA)

postsynaptic density (IDA)

postsynaptic density membrane (ISO)

postsynaptic membrane (ISO)

synapse (IBA)

Molecular Function

channel regulator activity (ISO)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal AMPA-mediated synaptic currents (IAGP)

abnormal bone structure (IEA)

abnormal miniature excitatory postsynaptic currents (IAGP)

decreased circulating calcium level (IEA)

hyperactivity (IEA)

increased circulating alkaline phosphatase level (IEA)

increased exploration in new environment (IEA)

increased vertical activity (IEA)

no abnormal phenotype detected (IAGP)

reduced AMPA-mediated synaptic currents (IAGP)

reduced long term potentiation (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Database resources of the National Center for Biotechnology Information.	Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.

Additional References at PubMed

PMID:10022955	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12477932	PMID:14681479	PMID:15782199	PMID:16141072	PMID:16141073	PMID:20805473	PMID:21172611
PMID:21343286	PMID:21543622	PMID:21677750	PMID:21873635	PMID:21993243	PMID:23522044	PMID:24194600	PMID:25218043	PMID:34079129

Genomics

Comparative Map Data

Cnih2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	5,142,896 - 5,148,549 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	5,142,896 - 5,148,549 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	5,092,868 - 5,098,521 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	5,092,868 - 5,098,521 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	5,092,871 - 5,098,418 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	5,092,871 - 5,098,418 (-)	NCBI		MGSCv36	mm8
Celera	19	4,962,069 - 4,967,624 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI

CNIH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	66,278,175 - 66,284,206 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	11	66,278,175 - 66,285,301 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	66,045,646 - 66,051,677 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	65,802,272 - 65,808,259 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	65,802,271 - 65,808,259	NCBI
Celera	11	63,367,976 - 63,371,496 (+)	NCBI		Celera
Cytogenetic Map	11	q13.2	NCBI
HuRef	11	62,361,871 - 62,376,861 (+)	NCBI		HuRef
CHM1_1	11	65,929,773 - 65,935,793 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	66,271,838 - 66,277,869 (+)	NCBI		T2T-CHM13v2.0

Cnih2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	202,399,416 - 202,405,110 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	202,399,419 - 202,405,089 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	210,752,476 - 210,758,122 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	217,844,858 - 217,850,504 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	210,535,892 - 210,541,538 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	220,474,485 - 220,480,723 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	220,474,493 - 220,480,132 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	227,405,539 - 227,411,210 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	207,715,692 - 207,717,588 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	207,869,147 - 207,871,037 (-)	NCBI
Celera	1	199,939,495 - 199,944,513 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Cnih2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	19,033,201 - 19,035,138 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	19,033,201 - 19,035,135 (-)	NCBI	ChiLan1.0	ChiLan1.0

CNIH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	11	68,554,863 - 68,560,863 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	61,643,633 - 61,649,646 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	64,969,447 - 64,975,156 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	64,969,447 - 64,975,156 (+)	Ensembl	panpan1.1		panPan2

CNIH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	51,020,263 - 51,026,280 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	51,021,116 - 51,026,273 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	49,628,921 - 49,634,836 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	52,058,624 - 52,064,534 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	52,059,259 - 52,064,720 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	51,158,624 - 51,164,533 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	50,732,786 - 50,738,700 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	51,522,930 - 51,528,840 (-)	NCBI		UU_Cfam_GSD_1.0

Cnih2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	6,868,527 - 6,874,251 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	3,310,872 - 3,316,573 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936599	3,310,873 - 3,316,575 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CNIH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	6,102,347 - 6,109,424 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	5,178,633 - 5,184,482 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CNIH2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	7,982,685 - 7,988,834 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	7,982,700 - 7,988,753 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	105,264,377 - 105,270,384 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cnih2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	20,084,501 - 20,090,209 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	20,084,526 - 20,090,225 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cnih2
150 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	378
Count of miRNA genes:	252
Interacting mature miRNAs:	299
Transcripts:	ENSMUST00000025805
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300776	Lfp3_m	long free running period 3 (mouse)			Not determined		19	1	20328703	Mouse
4142161	Drinksac2_m	drink saccharin 2 (mouse)			Not determined			1	20695286	Mouse
4142302	Nstr1_m	nerve sheath tumor resistance QTL 1 (mouse)			Not determined		19	1	22371338	Mouse
1301271	Datd_m	dopamine transporter density (mouse)			Not determined		19	1	32340234	Mouse
4142406	Pbctlp1_m	peripheral blood cytotoxic T lymphocyte percentage 1 (mouse)			Not determined			1	32875174	Mouse
1300904	Chab5_m	cholesterol absorption 5 (mouse)			Not determined		19	1653764	35653927	Mouse
26884385	Skwq14_m	skull length QTL 14, 16 week (mouse)					19	3250000	35877400	Mouse
1301800	Faq10_m	fluctuating asymmetry QTL 10 (mouse)			Not determined		19	3323216	37323348	Mouse
1300923	Bits4_m	bitterness sensitivity 4 (mouse)			Not determined		19	3323216	37323348	Mouse
1302126	Skull26_m	skull morphology 26 (mouse)			Not determined		19	3323216	37323348	Mouse
1300591	Pas3_m	pulmonary adenoma susceptibility 3 (mouse)			Not determined		19	3323216	37323348	Mouse
1357819	Tgct2_m	testicular germ cell tumor 2 (mouse)			Not determined		19	3328551	20539663	Mouse
25394536	Skmw86_m	skeletal muscle weight 86, TA (mouse)					19	5064817	8957825	Mouse

Markers in Region

Cnih2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	5,092,900 - 5,093,309	UniSTS	GRCm38
MGSCv37	19	5,092,900 - 5,093,309	UniSTS	GRCm37
Celera	19	4,962,098 - 4,962,507	UniSTS
Cytogenetic Map	19	A	UniSTS
cM Map	19		UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001302333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_009920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB006191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC124502	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK141483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK211408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC059922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC103797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC144739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX243776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000025805 ⟹ ENSMUSP00000025805

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	5,142,896 - 5,148,549 (-)	Ensembl
GRCm38.p6 Ensembl	19	5,092,868 - 5,098,521 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000235638 ⟹ ENSMUSP00000157729

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	5,143,155 - 5,148,410 (-)	Ensembl
GRCm38.p6 Ensembl	19	5,093,127 - 5,098,382 (-)	Ensembl

RefSeq Acc Id:

NM_001302333 ⟹ NP_001289262

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	19	5,142,896 - 5,148,549 (-)	NCBI
GRCm38	19	5,092,868 - 5,098,521 (-)	NCBI
Celera	19	4,962,066 - 4,967,727 (-)	NCBI

Sequence:

show sequence

GAGCGAGGGAGCCGCGGGCGAGGGATCGCAGGATGAGCGATCGGGGCCCGGGCAGCCGGCAGCG
GACGCGCCCCCCGAGCCCCACGGCCCGCGCCCCGCGTCCCCCACGGCCTCGTGGCCCTGGTCCC
GGACGCGCTGTCCGTGTCCCTAGAGTCCGGTGGGCCATGCCCGTCCGGCCCTAAGTGTGGGCCG
GGGGGCGTCCCCTTGCGCCCAGACCCCGCGCTGGCGCCCCCCGGGCCACCGCCCGGCGCGGGGG
CCATGGCGTTCACCTTCGCAGCATTCTGCTACATGCTCACCCTGGTGCTGTGCGCCTCCCTCAT
CTTCTTTGTCATCTGGCACATCATAGCCTTTGATGAGCTGCGGACTGACTTCAAGAACCCCATC
GACCAGGGGAACCCAGCGCGGGCAGTAAGTGATACATGTGCTGTGCTGAGCGCGAGCGTTTGAA
AAACATCGAACGCATCTGCTGCCTCCTGAGGAAGCTGGTGGTCCCGGAATATTCCATCCACGGC
CTCTTCTGTCTGATGTTTCTGTGTGCAGCAGAGTGGGTGACCCTGGGCCTCAACATCCCCCTCC
TCTTCTACCACCTCTGGAGGTACTTCCACCGTCCTGCGGATGGCTCTGAGGTCATGTATGATGC
GGTCTCTATCATGAATGCTGACATCCTCAACTACTGCCAGAAGGAGTCCTGGTGCAAACTCGCC
TTCTACCTGCTGTCCTTCTTCTATTACCTGTACAGTATGGTTTATACGTTGGTGAGCTTCTAAG
GGGGAAGCCGGCCAGGGAGCAAGCCCAGAACGGACCGGACGCCTGTGCACCCCCAGCCCTGCCC
CTCTGGCCACAGAGGCCTCAGCCCTGGGGAGGGAGGAGGCACTGGTGCCTCCAGCCTCTCCACC
CCCCAAACTGCTGCTGCGGGGACCCCCGCCTTCAGAGCTCTCCCCTTCTGACTAGGGCCAGGCA
AAGCTCTAAACGGGTGGGGGCTTCTCTGCTAGCCTGCAGCTAGGCATGGCAGTTGTCCTGGAAG
GGGTAGGACTTCCGGTTTTGTCCGCTCCAGGGGAATTTGGGCCCTGCCAACAGGCAGACCTTGA
TCCTGGAAATACTGGGCAGCCCACCTTGGCCCTCACCCTGAAGCTCCCCGTGCAGGTGGGGGGG
CACCTACACCAGGAATGAGCAGGCTCAACATGGGGGCAGCCCCATCCCTAGTCTGCCCTCCCCC
CTCCCCAGGCTCTCTCTCCAACCCAGTCTCTACTTATCCCAAATCCAACCTACCCTGTCCCTTG
GACCTATTTTCTATGTTGCCTGGAGGAGTCCAGCACCCCATCCCCTGACATTTGTGACAAAATA
TGAATAAACTACTGAAAACACACAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_009920 ⟹ NP_034050

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	19	5,142,896 - 5,148,549 (-)	NCBI
GRCm38	19	5,092,868 - 5,098,521 (-)	NCBI
MGSCv37	19	5,092,871 - 5,098,418 (-)	RGD
Celera	19	4,962,066 - 4,967,727 (-)	NCBI
cM Map	19		ENTREZGENE

Sequence:

show sequence

GAGCGAGGGAGCCGCGGGCGAGGGATCGCAGGATGAGCGATCGGGGCCCGGGCAGCCGGCAGCG
GACGCGCCCCCCGAGCCCCACGGCCCGCGCCCCGCGTCCCCCACGGCCTCGTGGCCCTGGTCCC
GGACGCGCTGTCCGTGTCCCTAGAGTCCGGTGGGCCATGCCCGTCCGGCCCTAAGTGTGGGCCG
GGGGGCGTCCCCTTGCGCCCAGACCCCGCGCTGGCGCCCCCCGGGCCACCGCCCGGCGCGGGGG
CCATGGCGTTCACCTTCGCAGCATTCTGCTACATGCTCACCCTGGTGCTGTGCGCCTCCCTCAT
CTTCTTTGTCATCTGGCACATCATAGCCTTTGATGAGCTGCGGACTGACTTCAAGAACCCCATC
GACCAGGGGAACCCAGCGCGGGCACGCGAGCGTTTGAAAAACATCGAACGCATCTGCTGCCTCC
TGAGGAAGCTGGTGGTCCCGGAATATTCCATCCACGGCCTCTTCTGTCTGATGTTTCTGTGTGC
AGCAGAGTGGGTGACCCTGGGCCTCAACATCCCCCTCCTCTTCTACCACCTCTGGAGGTACTTC
CACCGTCCTGCGGATGGCTCTGAGGTCATGTATGATGCGGTCTCTATCATGAATGCTGACATCC
TCAACTACTGCCAGAAGGAGTCCTGGTGCAAACTCGCCTTCTACCTGCTGTCCTTCTTCTATTA
CCTGTACAGTATGGTTTATACGTTGGTGAGCTTCTAAGGGGGAAGCCGGCCAGGGAGCAAGCCC
AGAACGGACCGGACGCCTGTGCACCCCCAGCCCTGCCCCTCTGGCCACAGAGGCCTCAGCCCTG
GGGAGGGAGGAGGCACTGGTGCCTCCAGCCTCTCCACCCCCCAAACTGCTGCTGCGGGGACCCC
CGCCTTCAGAGCTCTCCCCTTCTGACTAGGGCCAGGCAAAGCTCTAAACGGGTGGGGGCTTCTC
TGCTAGCCTGCAGCTAGGCATGGCAGTTGTCCTGGAAGGGGTAGGACTTCCGGTTTTGTCCGCT
CCAGGGGAATTTGGGCCCTGCCAACAGGCAGACCTTGATCCTGGAAATACTGGGCAGCCCACCT
TGGCCCTCACCCTGAAGCTCCCCGTGCAGGTGGGGGGGCACCTACACCAGGAATGAGCAGGCTC
AACATGGGGGCAGCCCCATCCCTAGTCTGCCCTCCCCCCTCCCCAGGCTCTCTCTCCAACCCAG
TCTCTACTTATCCCAAATCCAACCTACCCTGTCCCTTGGACCTATTTTCTATGTTGCCTGGAGG
AGTCCAGCACCCCATCCCCTGACATTTGTGACAAAATATGAATAAACTACTGAAAACACACAAA
AAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001289262	(Get FASTA)	NCBI Sequence Viewer
	NP_034050	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI03798	(Get FASTA)	NCBI Sequence Viewer
	AAI37586	(Get FASTA)	NCBI Sequence Viewer
	AAI37587	(Get FASTA)	NCBI Sequence Viewer
	BAA21746	(Get FASTA)	NCBI Sequence Viewer
	BAE24698	(Get FASTA)	NCBI Sequence Viewer
	EDL33101	(Get FASTA)	NCBI Sequence Viewer
	EDL33102	(Get FASTA)	NCBI Sequence Viewer
	O35089	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_034050 ⟸ NM_009920
- Peptide Label:	isoform 1
- UniProtKB:	O35089 (UniProtKB/Swiss-Prot), Q3SYI8 (UniProtKB/TrEMBL), A0A6P5P0A6 (UniProtKB/TrEMBL), A0A8C6GET6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLL RKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADIL NYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF hide sequence

RefSeq Acc Id:	NP_001289262 ⟸ NM_001302333
- Peptide Label:	isoform 2
- UniProtKB:	Q3SYI8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCCAERERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRP ADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF hide sequence

RefSeq Acc Id:

ENSMUSP00000025805 ⟸ ENSMUST00000025805

RefSeq Acc Id:

ENSMUSP00000157729 ⟸ ENSMUST00000235638

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35089-F1-model_v2	AlphaFold	O35089	1-160	view protein structure

Promoters

RGD ID:

6829912

Promoter ID:

MM_KWN:26054

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000025805

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	19	5,098,276 - 5,098,977 (-)	MPROMDB

RGD ID:

13678488

Promoter ID:

EPDNEW_M23394

Type:

initiation region

Name:

Cnih2_1

Description:

Mus musculus cornichon family AMPA receptor auxiliary protein2 , transcript variant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	5,098,494 - 5,098,554	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1277225	AgrOrtholog
Ensembl Genes	ENSMUSG00000024873	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000025805	ENTREZGENE
	ENSMUSP00000025805.7	UniProtKB/Swiss-Prot
	ENSMUSP00000157729.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000025805	ENTREZGENE
	ENSMUST00000025805.8	UniProtKB/Swiss-Prot
	ENSMUST00000235638.2	UniProtKB/TrEMBL
InterPro	Cornichon	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cornichon_conserved	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:12794	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1277225	ENTREZGENE
NCBI Gene	12794	ENTREZGENE
PANTHER	CORNICHON-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN CORNICHON HOMOLOG 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Cornichon	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cnih2	PhenoGen
PROSITE	CORNICHON	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	Cornichon	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A494B9S6_MOUSE	UniProtKB/TrEMBL
	A0A6P5P0A6	ENTREZGENE
	A0A8C6GET6	ENTREZGENE
	CNIH2_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q3SYI8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-22	Cnih2	cornichon family AMPA receptor auxiliary protein 2		cornichon homolog 2 (Drosophila)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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