Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Msrb3 (methionine sulfoxide reductase B3) Mus musculus
Symbol: Msrb3
Name: methionine sulfoxide reductase B3
RGD ID: 1552761
Description: Predicted to have peptide-methionine (R)-S-oxide reductase activity and zinc ion binding activity. Predicted to be involved in protein repair. Predicted to localize to endoplasmic reticulum and mitochondrion. Is expressed in several structures, including heart; inner ear; jaw; limb; and skeleton. Used to study autosomal recessive nonsyndromic deafness 74. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 74. Orthologous to human MSRB3 (methionine sulfoxide reductase B3); PARTICIPATES IN glycine N-methyltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D430026P16Rik; I-8-23; methionine-R-sulfoxide reductase B3, mitochondrial; MsrB2
Homo sapiens (human) : MSRB3 (methionine sulfoxide reductase B3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Msrb3 (methionine sulfoxide reductase B3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msrb3 (methionine sulfoxide reductase B3)
Pan paniscus (bonobo/pygmy chimpanzee) : MSRB3 (methionine sulfoxide reductase B3)
Canis lupus familiaris (dog) : MSRB3 (methionine sulfoxide reductase B3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msrb3 (methionine sulfoxide reductase B3)
Sus scrofa (pig) : MSRB3 (methionine sulfoxide reductase B3)
Chlorocebus sabaeus (African green monkey) : MSRB3 (methionine sulfoxide reductase B3)
Heterocephalus glaber (naked mole-rat) : Msrb3 (methionine sulfoxide reductase B3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910120,617,005 - 120,735,132 (-)NCBI
GRCm3810120,781,100 - 120,899,011 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10120,781,096 - 120,899,101 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710120,218,156 - 120,336,027 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,184,160 - 120,274,211 (-)NCBImm8
Celera10123,146,728 - 123,236,798 (-)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Msrb3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552761
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.