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Gene: Msrb3 (methionine sulfoxide reductase B3) Mus musculus
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Symbol: Msrb3
Name: methionine sulfoxide reductase B3
RGD ID: 1552761
Description: Predicted to have peptide-methionine (R)-S-oxide reductase activity and zinc ion binding activity. Predicted to be involved in protein repair. Predicted to localize to endoplasmic reticulum and mitochondrion. Is expressed in several structures, including heart; inner ear; jaw; limb; and skeleton. Used to study autosomal recessive nonsyndromic deafness 74. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 74. Orthologous to human MSRB3 (methionine sulfoxide reductase B3); PARTICIPATES IN glycine N-methyltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D430026P16Rik; I-8-23; methionine-R-sulfoxide reductase B3, mitochondrial; MsrB2
Orthologs:
Homo sapiens (human) : MSRB3 (methionine sulfoxide reductase B3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Msrb3 (methionine sulfoxide reductase B3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msrb3 (methionine sulfoxide reductase B3)
Pan paniscus (bonobo/pygmy chimpanzee) : MSRB3 (methionine sulfoxide reductase B3)
Canis lupus familiaris (dog) : MSRB3 (methionine sulfoxide reductase B3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msrb3 (methionine sulfoxide reductase B3)
Sus scrofa (pig) : MSRB3 (methionine sulfoxide reductase B3)
Chlorocebus sabaeus (African green monkey) : MSRB3 (methionine sulfoxide reductase B3)
Heterocephalus glaber (naked mole-rat) : Msrb3 (methionine sulfoxide reductase B3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910120,617,005 - 120,735,132 (-)NCBI
GRCm3810120,781,100 - 120,899,011 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10120,781,096 - 120,899,101 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710120,218,156 - 120,336,027 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,184,160 - 120,274,211 (-)NCBImm8
Celera10123,146,728 - 123,236,798 (-)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Msrb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552761
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.