Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ubr5 (ubiquitin protein ligase E3 component n-recognin 5) Mus musculus
Analyze
Symbol: Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Description: Predicted to have ubiquitin-ubiquitin ligase activity. Involved in negative regulation of interleukin-17 secretion and regulation of protein stability. Predicted to localize to several cellular components, including the cytosol; nucleoplasm; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Is expressed in cranial ganglion; nervous system; sensory organ; submandibular gland primordium; and vibrissa. Orthologous to human UBR5 (ubiquitin protein ligase E3 component n-recognin 5); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4432411E13Rik; AW549941; C77315; D030042K14; E3 ubiquitin protein ligase, HECT domain containing, 1; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; Edd; Edd1; extraembryonic development; HECT-type E3 ubiquitin transferase UBR5; hyperplastic discs protein homolog; mKIAA0896
Orthologs:
Related Pseudogenes: Gm19037  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1537,967,328 - 38,078,854 (-)Ensembl
GRCm381537,967,328 - 38,078,862 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371537,897,083 - 38,008,608 (-)NCBIGRCm37mm9NCBIm37
MGSCv361537,911,917 - 38,023,442 (-)NCBImm8
Celera1538,586,135 - 38,667,882 (-)NCBICelera
Cytogenetic Map15 B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ubr5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552737
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.