Tspan11 (tetraspanin 11) - Rat Genome Database

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Gene: Tspan11 (tetraspanin 11) Mus musculus
Analyze
Symbol: Tspan11
Name: tetraspanin 11
RGD ID: 1552634
MGI Page MGI
Description: Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and skin. Orthologous to human TSPAN11 (tetraspanin 11).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1110014F12Rik; AU067806; expressed sequence AU067806; tetraspanin-11; tspan-11
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396127,864,585 - 127,930,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6127,864,552 - 127,930,940 (+)EnsemblGRCm39 Ensembl
GRCm386127,887,509 - 127,953,031 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6127,887,589 - 127,953,977 (+)EnsemblGRCm38mm10GRCm38
MGSCv376127,837,640 - 127,903,049 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366127,853,241 - 127,918,650 (+)NCBIMGSCv36mm8
Celera6129,562,702 - 129,626,037 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map662.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11756464   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18291621   PMID:21267068   PMID:21677750   PMID:21873635  
PMID:24194600   PMID:31030082   PMID:38355793  


Genomics

Comparative Map Data
Tspan11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396127,864,585 - 127,930,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6127,864,552 - 127,930,940 (+)EnsemblGRCm39 Ensembl
GRCm386127,887,509 - 127,953,031 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6127,887,589 - 127,953,977 (+)EnsemblGRCm38mm10GRCm38
MGSCv376127,837,640 - 127,903,049 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366127,853,241 - 127,918,650 (+)NCBIMGSCv36mm8
Celera6129,562,702 - 129,626,037 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map662.56NCBI
TSPAN11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381230,926,748 - 31,016,502 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1230,926,428 - 30,996,602 (+)EnsemblGRCh38hg38GRCh38
GRCh371231,079,682 - 31,149,534 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361230,971,105 - 31,036,722 (+)NCBINCBI36Build 36hg18NCBI36
Celera1236,222,678 - 36,292,351 (+)NCBICelera
Cytogenetic Map12p11.21NCBI
HuRef1230,844,681 - 30,914,774 (+)NCBIHuRef
CHM1_11231,044,883 - 31,114,476 (+)NCBICHM1_1
T2T-CHM13v2.01230,801,368 - 30,891,025 (+)NCBIT2T-CHM13v2.0
Tspan11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84162,424,327 - 162,491,653 (+)NCBIGRCr8
mRatBN7.24160,738,149 - 160,805,522 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4160,738,404 - 160,805,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4166,968,306 - 167,035,474 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04162,751,216 - 162,818,393 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04161,385,290 - 161,452,456 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04160,455,845 - 160,522,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4160,455,986 - 160,522,904 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04231,093,058 - 231,159,405 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44164,340,111 - 164,407,946 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14164,585,046 - 164,652,881 (+)NCBI
Celera4149,446,650 - 149,513,483 (+)NCBICelera
Cytogenetic Map4q42NCBI
TSPAN11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21065,789,252 - 65,859,187 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11265,782,194 - 65,855,580 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01255,283,377 - 55,358,044 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11257,914,874 - 57,957,465 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1257,919,656 - 57,985,438 (-)Ensemblpanpan1.1panPan2
TSPAN11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12741,478,505 - 41,521,229 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2741,477,938 - 41,517,173 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,161,461 - 5,236,303 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02741,804,050 - 41,878,861 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2741,803,552 - 41,878,843 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12741,741,365 - 41,816,167 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02741,716,360 - 41,791,138 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,521,780 - 4,596,612 (-)NCBIUU_Cfam_GSD_1.0
Tspan11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945105,516,023 - 105,589,467 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366063,599,271 - 3,639,013 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366063,594,698 - 3,668,319 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl566,853,404 - 66,911,569 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1566,852,803 - 66,911,610 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2569,160,214 - 69,217,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11130,607,817 - 30,678,693 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1130,607,875 - 30,678,790 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660694,308,844 - 4,377,847 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspan11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624860581,951 - 617,163 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624860579,614 - 637,069 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2065
Count of miRNA genes:781
Interacting mature miRNAs:1030
Transcripts:ENSMUST00000032501, ENSMUST00000149801
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125333609134096586Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116641858128495988Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127815180136022150Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse

Markers in Region
D6Mit377  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386127,929,379 - 127,929,527UniSTSGRCm38
MGSCv376127,879,397 - 127,879,545UniSTSGRCm37
Celera6129,604,581 - 129,604,727UniSTS
Cytogenetic Map6F3UniSTS
cM Map660.7UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000032501   ⟹   ENSMUSP00000032501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6127,864,552 - 127,930,940 (+)Ensembl
GRCm38.p6 Ensembl6127,887,589 - 127,953,977 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149801
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6127,864,735 - 127,900,844 (+)Ensembl
GRCm38.p6 Ensembl6127,887,772 - 127,923,881 (+)Ensembl
RefSeq Acc Id: NM_026743   ⟹   NP_081019
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396127,864,585 - 127,929,994 (+)NCBI
GRCm386127,887,622 - 127,953,031 (+)NCBI
MGSCv376127,837,640 - 127,903,049 (+)RGD
Celera6129,562,702 - 129,626,037 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036152281   ⟹   XP_036008174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396127,866,263 - 127,930,940 (+)NCBI
Sequence:
RefSeq Acc Id: NP_081019   ⟸   NM_026743
- UniProtKB: Q9D1D1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000032501   ⟸   ENSMUST00000032501
RefSeq Acc Id: XP_036008174   ⟸   XM_036152281
- Peptide Label: isoform X1
- UniProtKB: Q9D1D1 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D1D1-F1-model_v2 AlphaFold Q9D1D1 1-253 view protein structure

Promoters
RGD ID:6840114
Promoter ID:MM_KWN:47754
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1
Transcripts:OTTMUST00000066926,   OTTMUST00000066931
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366127,837,699 - 127,838,199 (+)MPROMDB
RGD ID:6891118
Promoter ID:EPDNEW_M9010
Type:initiation region
Name:Tspan11_1
Description:Mus musculus tetraspanin 11 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386127,887,771 - 127,887,831EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915748 AgrOrtholog
Ensembl Genes ENSMUSG00000030351 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000032501 ENTREZGENE
  ENSMUST00000032501.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1450.10 UniProtKB/Swiss-Prot
InterPro Tetraspanin UniProtKB/Swiss-Prot
  Tetraspanin/Peripherin UniProtKB/Swiss-Prot
  Tetraspanin_EC2_sf UniProtKB/Swiss-Prot
KEGG Report mmu:68498 UniProtKB/Swiss-Prot
MGD MGI:1915748 ENTREZGENE
NCBI Gene 68498 ENTREZGENE
PANTHER PTHR19282 UniProtKB/Swiss-Prot
  TETRASPANIN-11 UniProtKB/Swiss-Prot
Pfam Tetraspanin UniProtKB/Swiss-Prot
PhenoGen Tspan11 PhenoGen
PIRSF Tetraspanin UniProtKB/Swiss-Prot
PRINTS TMFOUR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48652 UniProtKB/Swiss-Prot
UniProt Q9D1D1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-08 Tspan11  tetraspanin 11  AU067806  expressed sequence AU067806  Data merged from RGD:1607838 737654 PROVISIONAL