Kif3a (kinesin family member 3A) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Kif3a (kinesin family member 3A) Mus musculus
Analyze
Symbol: Kif3a
Name: kinesin family member 3A
RGD ID: 1552608
MGI Page MGI
Description: Enables intraciliary transport particle B binding activity and microtubule binding activity. Involved in several processes, including dorsal/ventral neural tube patterning; microtubule cytoskeleton organization; and smoothened signaling pathway. Acts upstream of or within several processes, including chordate embryonic development; plasma membrane bounded cell projection organization; and regionalization. Located in centriole; motile cilium; and photoreceptor connecting cilium. Part of kinesin II complex. Is expressed in several structures, including gonad; liver; nervous system; node; and spleen. Used to study dysostosis; polycystic kidney disease; and polycystic kidney disease 1. Orthologous to human KIF3A (kinesin family member 3A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 111-11-71; 111-11-86; AW124694; DNA sequence AF180004; DNA sequence AF180009; Ki; Kif; Kif3; Kifl; kinesin family-like; kinesin-II subunit; kinesin-like protein KIF3A; Kn; Kns3; microtubule plus end-directed kinesin motor 3A; N-4 kinesin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,456,531 - 53,495,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,458,206 - 53,492,794 (+)EnsemblGRCm39 Ensembl
GRCm381153,565,701 - 53,604,248 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,567,379 - 53,601,967 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,380,881 - 53,417,746 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,410,826 - 53,445,377 (+)NCBIMGSCv36mm8
Celera1158,146,946 - 58,183,772 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal actin cytoskeleton morphology  (IAGP)
abnormal basicranium morphology  (IAGP)
abnormal basisphenoid bone morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cauda epididymis morphology  (IAGP)
abnormal chondrocyte morphology  (IAGP)
abnormal cranial neural crest cell morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal direction of heart looping  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryo turning  (IAGP)
abnormal endochondral bone ossification  (IAGP)
abnormal epididymis morphology  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal heart looping  (IAGP)
abnormal left-right axis patterning  (IAGP)
abnormal limb bud morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone epiphysis morphology  (IAGP)
abnormal long bone hypertrophic chondrocyte zone  (IAGP)
abnormal manchette disassembly  (IAGP)
abnormal manchette morphology  (IAGP)
abnormal manchette perinuclear ring morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal nasal bone morphology  (IAGP)
abnormal nasal septum morphology  (IAGP)
abnormal nervous system development  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal outer dense fiber morphology  (IAGP)
abnormal palatine bone morphology  (IAGP)
abnormal photoreceptor inner segment morphology  (IAGP)
abnormal premaxilla morphology  (IAGP)
abnormal primitive node morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal sperm axoneme morphology  (IAGP)
abnormal sperm fibrous sheath morphology  (IAGP)
abnormal sperm flagellum morphology  (IAGP)
abnormal sperm head morphology  (IAGP)
abnormal sperm mitochondrial sheath morphology  (IAGP)
abnormal sperm nucleus morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal spinal cord morphology  (IAGP)
absent corpus callosum  (IAGP)
absent embryonic cilia  (IAGP)
absent kidney epithelial cell primary cilium  (IAGP)
absent mandibular condyloid process  (IAGP)
absent mandibular ramus  (IAGP)
absent nodal flow  (IAGP)
anterior cranium occultum  (IAGP)
broad frontonasal prominence  (IAGP)
caudal body truncation  (IAGP)
cleft secondary palate  (IAGP)
decreased body size  (IAGP)
decreased embryo size  (IAGP)
decreased epididymis weight  (IAGP)
decreased length of long bones  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased testis weight  (IAGP)
delayed heart looping  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
disproportionate dwarf  (IAGP)
distended pericardium  (IAGP)
ectopic manchette  (IAGP)
elongated manchette  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged kidney  (IAGP)
hydrocephaly  (IAGP)
incomplete embryo turning  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased cranial neural crest cell proliferation  (IAGP)
increased kidney apoptosis  (IAGP)
kidney cortex cyst  (IAGP)
kidney cyst  (IAGP)
kidney failure  (IAGP)
kidney medulla cyst  (IAGP)
lethargy  (IAGP)
male infertility  (IAGP)
myocardium hypoplasia  (IAGP)
neural tube degeneration  (IAGP)
ocular hypertelorism  (IAGP)
oligozoospermia  (IAGP)
pericardial edema  (IAGP)
pericardial effusion  (IAGP)
polycystic kidney  (IAGP)
polydactyly  (IAGP)
postnatal growth retardation  (IAGP)
renal interstitial fibrosis  (IAGP)
renal tubule atrophy  (IAGP)
retina photoreceptor degeneration  (IAGP)
short limbs  (IAGP)
short mandible  (IAGP)
short photoreceptor inner segment  (IAGP)
short photoreceptor outer segment  (IAGP)
situs inversus  (IAGP)
small pharyngeal arch  (IAGP)
spina bifida occulta  (IAGP)
thoracic vertebral fusion  (IAGP)
wavy neural tube  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex. Li S, etal., Theranostics. 2020 Jan 1;10(4):1719-1732. doi: 10.7150/thno.37049. eCollection 2020.
2. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Lin F, etal., Proc Natl Acad Sci U S A 2003 Apr 29;100(9):5286-91.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. All kinesin superfamily protein, KIF, genes in mouse and human. Miki H, etal., Proc Natl Acad Sci U S A 2001 Jun 19;98(13):7004-11.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Rho GTPases in insulin-stimulated glucose uptake. Satoh T Small GTPases. 2014;5:e28102. doi: 10.4161/sgtp.28102. Epub 2014 Mar 10.
Additional References at PubMed
PMID:1447303   PMID:7515068   PMID:7559760   PMID:8889548   PMID:9115736   PMID:9149945   PMID:9275178   PMID:9339368   PMID:10220415   PMID:10330409   PMID:10349636   PMID:10631107  
PMID:10652513   PMID:10655497   PMID:10704283   PMID:10704402   PMID:10922068   PMID:10943838   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11331403   PMID:11389549   PMID:12477932  
PMID:12520002   PMID:12533605   PMID:12646135   PMID:12730123   PMID:12821668   PMID:12832475   PMID:14603322   PMID:14610273   PMID:15029248   PMID:15067314   PMID:15345747   PMID:15755804  
PMID:15889083   PMID:16061793   PMID:16141072   PMID:16141073   PMID:16298999   PMID:16337628   PMID:16632484   PMID:16782012   PMID:17061268   PMID:17065525   PMID:17123526   PMID:17166921  
PMID:17251353   PMID:17359961   PMID:17360631   PMID:17507416   PMID:17698054   PMID:17804638   PMID:17825299   PMID:17825558   PMID:17898177   PMID:18066062   PMID:18084282   PMID:18263895  
PMID:18297065   PMID:18311719   PMID:18353302   PMID:18497258   PMID:18579360   PMID:18590716   PMID:18729223   PMID:18987668   PMID:19015237   PMID:19208653   PMID:19286674   PMID:19384852  
PMID:19596798   PMID:19684112   PMID:19701203   PMID:19701205   PMID:19906976   PMID:19940036   PMID:20066075   PMID:20106874   PMID:20172860   PMID:20360384   PMID:20381354   PMID:20643351  
PMID:20926680   PMID:21148103   PMID:21151991   PMID:21209331   PMID:21429982   PMID:21566205   PMID:21602792   PMID:21670265   PMID:21677750   PMID:21695114   PMID:21703454   PMID:21745638  
PMID:21752934   PMID:21873635   PMID:21909995   PMID:21969560   PMID:21976438   PMID:22357948   PMID:22428034   PMID:22473005   PMID:22541555   PMID:22632975   PMID:22784673   PMID:22855808  
PMID:22983710   PMID:23259947   PMID:23332756   PMID:23384121   PMID:23386061   PMID:23389290   PMID:23392690   PMID:23511952   PMID:23537390   PMID:23704327   PMID:23742838   PMID:23759744  
PMID:23762375   PMID:23831641   PMID:23892607   PMID:24656932   PMID:24659776   PMID:24739168   PMID:24780629   PMID:24797473   PMID:24887031   PMID:25114218   PMID:25122755   PMID:25294941  
PMID:25657001   PMID:25788526   PMID:25825494   PMID:26245936   PMID:26245976   PMID:26335646   PMID:26445448   PMID:26675708   PMID:26677864   PMID:26710851   PMID:26769565   PMID:27126173  
PMID:27181777   PMID:27214279   PMID:27214567   PMID:27272319   PMID:27637334   PMID:27793670   PMID:27794000   PMID:27802276   PMID:27993979   PMID:28286175   PMID:28291836   PMID:28346501  
PMID:28611083   PMID:28671696   PMID:28941984   PMID:29156524   PMID:29532549   PMID:29891944   PMID:29925518   PMID:30061390   PMID:30148884   PMID:30818997   PMID:30865891   PMID:31010494  
PMID:31040226   PMID:31746486   PMID:32238474   PMID:32290105   PMID:32325033   PMID:32568216   PMID:32571914   PMID:32743070   PMID:32796837   PMID:32935890   PMID:33046531   PMID:33144324  
PMID:33188191   PMID:33368703   PMID:34133714   PMID:34360830   PMID:34964466   PMID:36281991   PMID:37890489  


Genomics

Comparative Map Data
Kif3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,456,531 - 53,495,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,458,206 - 53,492,794 (+)EnsemblGRCm39 Ensembl
GRCm381153,565,701 - 53,604,248 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,567,379 - 53,601,967 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,380,881 - 53,417,746 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,410,826 - 53,445,377 (+)NCBIMGSCv36mm8
Celera1158,146,946 - 58,183,772 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.97NCBI
KIF3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,688,812 - 132,737,546 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,692,628 - 132,737,638 (-)EnsemblGRCh38hg38GRCh38
GRCh375132,028,323 - 132,073,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,056,222 - 132,101,164 (-)NCBINCBI36Build 36hg18NCBI36
Build 345132,059,220 - 132,101,163NCBI
Celera5128,158,460 - 128,203,363 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,220,971 - 127,265,873 (-)NCBIHuRef
CHM1_15131,461,606 - 131,506,536 (-)NCBICHM1_1
T2T-CHM13v2.05133,208,481 - 133,257,281 (-)NCBIT2T-CHM13v2.0
Kif3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,226,388 - 38,263,062 (+)NCBIGRCr8
mRatBN7.21037,725,930 - 37,761,183 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,725,970 - 37,759,191 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1042,418,009 - 42,451,222 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,908,061 - 41,941,287 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,411,789 - 37,445,019 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,918,705 - 38,953,958 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,918,748 - 38,952,785 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,700,206 - 38,734,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,029,351 - 39,062,570 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11039,057,446 - 39,068,547 (+)NCBI
Celera1037,070,450 - 37,103,611 (+)NCBICelera
Cytogenetic Map10q22NCBI
Kif3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554084,069,639 - 4,115,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554084,072,823 - 4,115,975 (-)NCBIChiLan1.0ChiLan1.0
KIF3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24128,004,995 - 128,049,749 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15126,144,560 - 126,189,314 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05128,112,636 - 128,154,443 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,268,505 - 134,315,431 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,274,352 - 134,315,431 (-)Ensemblpanpan1.1panPan2
KIF3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,988,516 - 21,044,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,928,655 - 21,044,090 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,790,183 - 19,845,775 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01121,774,466 - 21,830,159 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,774,475 - 21,830,123 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,492,965 - 20,548,637 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,340,508 - 20,396,333 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01120,983,018 - 21,038,700 (-)NCBIUU_Cfam_GSD_1.0
Kif3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,458,121 - 115,499,788 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366472,461,138 - 2,501,871 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366472,461,017 - 2,502,550 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,932,615 - 135,069,377 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,932,339 - 135,069,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,400,867 - 140,537,919 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KIF3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,496,770 - 35,554,536 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,514,130 - 35,551,472 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603442,387,830 - 42,436,606 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473339,354,232 - 39,407,121 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473339,354,360 - 39,406,574 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kif3a
1179 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1442
Count of miRNA genes:576
Interacting mature miRNAs:707
Transcripts:ENSMUST00000057330, ENSMUST00000118353, ENSMUST00000120613, ENSMUST00000130037, ENSMUST00000132496, ENSMUST00000132653, ENSMUST00000140359, ENSMUST00000173744
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
4141770Tcpm1_mT-cell phenotype modifier 1 (mouse)Not determined5145247953615930Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse

Markers in Region
AW124694  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,602,239 - 53,602,326UniSTSGRCm38
MGSCv371153,415,741 - 53,415,828UniSTSGRCm37
Celera1158,181,767 - 58,181,854UniSTS
Cytogenetic Map11A5-B1UniSTS
Whitehead/MRC_RH11722.69UniSTS
UniSTS:236577  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,602,401 - 53,602,606UniSTSGRCm38
MGSCv371153,415,903 - 53,416,108UniSTSGRCm37
Celera1158,181,929 - 58,182,134UniSTS
Cytogenetic Map11A5-B1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001290805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC005742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF180004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM231689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV356644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB752635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY237362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ157264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000057330   ⟹   ENSMUSP00000056197
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,458,206 - 53,491,932 (+)Ensembl
GRCm38.p6 Ensembl1153,567,379 - 53,601,105 (+)Ensembl
RefSeq Acc Id: ENSMUST00000118353   ⟹   ENSMUSP00000113848
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,458,353 - 53,491,886 (+)Ensembl
GRCm38.p6 Ensembl1153,567,526 - 53,601,059 (+)Ensembl
RefSeq Acc Id: ENSMUST00000120613   ⟹   ENSMUSP00000112782
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,458,206 - 53,492,794 (+)Ensembl
GRCm38.p6 Ensembl1153,567,379 - 53,601,967 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130037   ⟹   ENSMUSP00000116509
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,484,777 - 53,492,127 (+)Ensembl
GRCm38.p6 Ensembl1153,593,950 - 53,601,300 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132496   ⟹   ENSMUSP00000115161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,458,688 - 53,470,582 (+)Ensembl
GRCm38.p6 Ensembl1153,567,861 - 53,579,755 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132653   ⟹   ENSMUSP00000120388
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,469,942 - 53,477,722 (+)Ensembl
GRCm38.p6 Ensembl1153,579,115 - 53,586,895 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140359
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,458,543 - 53,469,957 (+)Ensembl
GRCm38.p6 Ensembl1153,567,716 - 53,579,130 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173744   ⟹   ENSMUSP00000133432
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1153,458,224 - 53,491,929 (+)Ensembl
GRCm38.p6 Ensembl1153,567,397 - 53,601,102 (+)Ensembl
RefSeq Acc Id: NM_001290805   ⟹   NP_001277734
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,458,196 - 53,495,073 (+)NCBI
GRCm381153,567,369 - 53,604,246 (+)NCBI
Celera1158,146,936 - 58,183,774 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001290806   ⟹   NP_001277735
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,458,196 - 53,495,073 (+)NCBI
GRCm381153,567,369 - 53,604,246 (+)NCBI
Celera1158,146,936 - 58,183,774 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008443   ⟹   NP_032469
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,458,196 - 53,495,073 (+)NCBI
GRCm381153,567,369 - 53,604,246 (+)NCBI
MGSCv371153,380,881 - 53,417,746 (+)RGD
Celera1158,146,936 - 58,183,774 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532325   ⟹   XP_006532388
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,456,531 - 53,495,075 (+)NCBI
GRCm381153,565,701 - 53,604,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532326   ⟹   XP_006532389
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,456,531 - 53,495,075 (+)NCBI
GRCm381153,565,701 - 53,604,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532328   ⟹   XP_006532391
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,456,531 - 53,495,075 (+)NCBI
GRCm381153,565,701 - 53,604,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156358   ⟹   XP_036012251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,456,531 - 53,495,075 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004936793
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,456,531 - 53,495,075 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032469   ⟸   NM_008443
- Peptide Label: isoform 1
- UniProtKB: Q7TSZ7 (UniProtKB/Swiss-Prot),   P28741 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532388   ⟸   XM_006532325
- Peptide Label: isoform X1
- UniProtKB: B1AQZ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006532391   ⟸   XM_006532328
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006532389   ⟸   XM_006532326
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001277735   ⟸   NM_001290806
- Peptide Label: isoform 3
- UniProtKB: Q3TET1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277734   ⟸   NM_001290805
- Peptide Label: isoform 2
- UniProtKB: Q3UI47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000116509   ⟸   ENSMUST00000130037
RefSeq Acc Id: ENSMUSP00000113848   ⟸   ENSMUST00000118353
RefSeq Acc Id: ENSMUSP00000115161   ⟸   ENSMUST00000132496
RefSeq Acc Id: ENSMUSP00000120388   ⟸   ENSMUST00000132653
RefSeq Acc Id: ENSMUSP00000112782   ⟸   ENSMUST00000120613
RefSeq Acc Id: ENSMUSP00000133432   ⟸   ENSMUST00000173744
RefSeq Acc Id: ENSMUSP00000056197   ⟸   ENSMUST00000057330
RefSeq Acc Id: XP_036012251   ⟸   XM_036156358
- Peptide Label: isoform X4
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28741-F1-model_v2 AlphaFold P28741 1-701 view protein structure

Promoters
RGD ID:6821184
Promoter ID:MM_KWN:7385
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4
Transcripts:ENSMUST00000057330,   ENSMUST00000108954,   ENSMUST00000118353,   NM_008443,   OTTMUST00000012534,   OTTMUST00000012540,   OTTMUST00000071554,   UC007IWK.1,   UC007IWM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361153,380,614 - 53,381,114 (+)MPROMDB
RGD ID:8674612
Promoter ID:EPDNEW_M15337
Type:initiation region
Name:Kif3a_1
Description:Mus musculus kinesin family member 3A , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15338  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381153,567,400 - 53,567,460EPDNEW
RGD ID:8674614
Promoter ID:EPDNEW_M15338
Type:initiation region
Name:Kif3a_2
Description:Mus musculus kinesin family member 3A , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15337  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381153,583,901 - 53,583,961EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107689 AgrOrtholog
Ensembl Genes ENSMUSG00000018395 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000057330 ENTREZGENE
  ENSMUST00000057330.15 UniProtKB/TrEMBL
  ENSMUST00000118353 ENTREZGENE
  ENSMUST00000118353.9 UniProtKB/TrEMBL
  ENSMUST00000120613 ENTREZGENE
  ENSMUST00000120613.9 UniProtKB/Swiss-Prot
  ENSMUST00000130037.2 UniProtKB/TrEMBL
  ENSMUST00000132496.3 UniProtKB/TrEMBL
  ENSMUST00000132653.2 UniProtKB/TrEMBL
  ENSMUST00000173744 ENTREZGENE
  ENSMUST00000173744.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16568 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107689 ENTREZGENE
NCBI Gene 16568 ENTREZGENE
PANTHER CENTROMERE PROTEIN E UniProtKB/TrEMBL
  CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB KIF3A RGD
PhenoGen Kif3a PhenoGen
PRINTS KINESINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART KISc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1AQZ2 ENTREZGENE, UniProtKB/TrEMBL
  B1AQZ5_MOUSE UniProtKB/TrEMBL
  F6V6Z9_MOUSE UniProtKB/TrEMBL
  F6VT70_MOUSE UniProtKB/TrEMBL
  KIF3A_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q2A657_MOUSE UniProtKB/TrEMBL
  Q3TET1 ENTREZGENE, UniProtKB/TrEMBL
  Q3TSP1_MOUSE UniProtKB/TrEMBL
  Q3TTS7_MOUSE UniProtKB/TrEMBL
  Q3UF02_MOUSE UniProtKB/TrEMBL
  Q3UI47 ENTREZGENE, UniProtKB/TrEMBL
  Q7TSZ7 ENTREZGENE
  Q80UK1_MOUSE UniProtKB/TrEMBL
  Q8CGJ1_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q7TSZ7 UniProtKB/Swiss-Prot