Or10a49 (olfactory receptor family 10 subfamily A member 49) - Rat Genome Database

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Gene: Or10a49 (olfactory receptor family 10 subfamily A member 49) Mus musculus
Analyze
Symbol: Or10a49
Name: olfactory receptor family 10 subfamily A member 49
RGD ID: 1552605
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR10A3 (olfactory receptor family 10 subfamily A member 3) and OR10A6 (olfactory receptor family 10 subfamily A member 6 (gene/pseudogene)).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2PBJ9-11199311-11198367; MOR268; MOR268-4; olfactory receptor 517; olfactory receptor MOR268-4; Olfr517
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397108,467,415 - 108,468,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7108,466,415 - 108,471,586 (-)EnsemblGRCm39 Ensembl
GRCm387108,868,208 - 108,869,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7108,867,208 - 108,872,379 (-)EnsemblGRCm38mm10GRCm38
MGSCv377116,011,722 - 116,012,666 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367108,659,385 - 108,660,329 (-)NCBIMGSCv36mm8
Celera7108,844,671 - 108,845,615 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or10a49
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397108,467,415 - 108,468,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7108,466,415 - 108,471,586 (-)EnsemblGRCm39 Ensembl
GRCm387108,868,208 - 108,869,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7108,867,208 - 108,872,379 (-)EnsemblGRCm38mm10GRCm38
MGSCv377116,011,722 - 116,012,666 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367108,659,385 - 108,660,329 (-)NCBIMGSCv36mm8
Celera7108,844,671 - 108,845,615 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.21NCBI
OR10A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,924,592 - 7,931,268 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,924,592 - 7,931,268 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,946,139 - 7,952,815 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,905,841 - 7,906,785 (-)NCBINCBI36Build 36hg18NCBI36
Build 34117,905,840 - 7,906,785NCBI
Celera118,064,777 - 8,065,721 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef117,615,953 - 7,616,897 (-)NCBIHuRef
CHM1_1117,948,238 - 7,949,182 (-)NCBICHM1_1
T2T-CHM13v2.0118,003,727 - 8,010,438 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in Or10a49
62 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:22
Interacting mature miRNAs:22
Transcripts:ENSMUST00000084753
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
25394573Skmw62_mskeletal muscle weight 62, gastroc (mouse)7106893715110612309Mouse
13524524Bodwtq6_mbody wweight QTL 6 (mouse)7107245693113055693Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000084753   ⟹   ENSMUSP00000081805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7108,467,328 - 108,468,382 (-)Ensembl
GRCm38.p6 Ensembl7108,868,121 - 108,869,175 (-)Ensembl
RefSeq Acc Id: ENSMUST00000216500   ⟹   ENSMUSP00000150980
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7108,466,415 - 108,471,586 (-)Ensembl
GRCm38.p6 Ensembl7108,867,208 - 108,872,379 (-)Ensembl
RefSeq Acc Id: NM_001011846   ⟹   NP_001011846
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397108,467,415 - 108,468,359 (-)NCBI
GRCm387108,868,208 - 108,869,152 (-)ENTREZGENE
MGSCv377116,011,722 - 116,012,666 (-)RGD
Celera7108,844,671 - 108,845,615 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001011846 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI50831 (Get FASTA)   NCBI Sequence Viewer  
  AAP71013 (Get FASTA)   NCBI Sequence Viewer  
  EDL16913 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000081805
  ENSMUSP00000081805.3
  ENSMUSP00000150980.2
Reference Protein Sequences
RefSeq Acc Id: NP_001011846   ⟸   NM_001011846
- UniProtKB: Q7TRU4 (UniProtKB/TrEMBL),   B9EKC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000081805   ⟸   ENSMUST00000084753
RefSeq Acc Id: ENSMUSP00000150980   ⟸   ENSMUST00000216500
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRU4-F1-model_v2 AlphaFold Q7TRU4 1-314 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030351 AgrOrtholog
Ensembl Genes ENSMUSG00000066240 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000084753 ENTREZGENE
  ENSMUST00000084753.3 UniProtKB/TrEMBL
  ENSMUST00000216500.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258136 UniProtKB/TrEMBL
MGD MGI:3030351 ENTREZGENE
NCBI Gene 258136 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 10A6 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or10a49 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt B9EKC9 ENTREZGENE, UniProtKB/TrEMBL
  Q7TRU4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-23 Or10a49  olfactory receptor family 10 subfamily A member 49  Olfr517  olfactory receptor 517  Symbol and/or name updated 27372883 PROVISIONAL