PHPT1 (phosphohistidine phosphatase 1) - Rat Genome Database

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Gene: PHPT1 (phosphohistidine phosphatase 1) Sus scrofa
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Symbol: PHPT1
Name: phosphohistidine phosphatase 1
RGD ID: 155260353
Description: ENCODES a protein that exhibits protein histidine phosphatase activity; actin filament binding (ortholog); calcium channel inhibitor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); lamellipodium organization (ortholog); negative regulation of T cell receptor signaling pathway (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); autosomal dominant nocturnal frontal lobe epilepsy 5 (ortholog); FOUND IN cytosol; leading edge of lamellipodium (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 14 kDa phosphohistidine phosphatase; PHP; PHP14; Protein histidine phosphatase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position: No map positions available.


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:12383260   PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
PHPT1
(Sus scrofa - pig)		 No map positions available.
PHPT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,849,409 - 136,851,024 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,848,724 - 136,851,027 (+)EnsemblGRCh38hg38GRCh38
GRCh379139,743,861 - 139,745,476 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,863,367 - 138,865,311 (+)NCBINCBI36Build 36hg18NCBI36
Build 349137,019,382 - 137,021,327NCBI
Celera9110,257,046 - 110,259,279 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,202,666 - 109,204,708 (+)NCBIHuRef
CHM1_19139,891,999 - 139,894,223 (+)NCBICHM1_1
T2T-CHM13v2.09149,083,591 - 149,085,206 (+)NCBIT2T-CHM13v2.0
Phpt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,463,442 - 25,465,528 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,463,442 - 25,465,236 (-)EnsemblGRCm39 Ensembl
GRCm38225,573,430 - 25,575,514 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,573,430 - 25,575,224 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,428,951 - 25,430,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,395,440 - 25,396,880 (-)NCBIMGSCv36mm8
Celera225,301,192 - 25,302,632 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.44NCBI
Phpt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,791,062 - 28,792,905 (-)NCBIGRCr8
mRatBN7.238,392,926 - 8,394,325 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx311,498,106 - 11,499,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,084,332 - 20,085,731 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,274,175 - 18,275,574 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,797,037 - 2,798,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,796,997 - 2,798,470 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,778,450 - 2,779,849 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,744,947 - 3,746,346 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,745,120 - 3,746,334 (-)NCBI
Celera33,217,877 - 3,219,276 (-)NCBICelera
Cytogenetic Map3p13NCBI
Phpt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,930,951 - 4,932,509 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555134,930,951 - 4,932,509 (+)NCBIChiLan1.0ChiLan1.0
PHPT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,551,316 - 2,553,397 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,553,651 - 2,555,698 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,906,160 - 107,908,130 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,877,274 - 136,878,317 (+)NCBIpanpan1.1PanPan1.1panPan2
PHPT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,736,310 - 48,737,771 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,736,333 - 48,737,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,949,921 - 47,951,381 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,614,346 - 49,615,806 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,614,371 - 49,615,763 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,390,569 - 48,392,028 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,689,275 - 48,690,734 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,736,240 - 48,737,700 (-)NCBIUU_Cfam_GSD_1.0
Phpt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,307,826 - 202,309,158 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,065,900 - 1,067,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,065,901 - 1,067,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHPT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,338,205 - 1,340,143 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,338,388 - 1,339,753 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660583,936,606 - 3,938,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Protein Sequences
Protein RefSeqs NP_001399201 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00070000097.1
GenBank Protein P59083 (Get FASTA)   NCBI Sequence Viewer  


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00070000065 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00070000111.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.50.20.20 UniProtKB/Swiss-Prot
InterPro Janus UniProtKB/Swiss-Prot
  Janus_sf UniProtKB/Swiss-Prot
NCBI Gene PHPT1 ENTREZGENE
PANTHER PTHR12258 UniProtKB/Swiss-Prot
  PTHR12258:SF10 UniProtKB/Swiss-Prot
Pfam Ocnus UniProtKB/Swiss-Prot
Superfamily-SCOP PHP14-like UniProtKB/Swiss-Prot
UniProt F1RWN4 ENTREZGENE
  P59083 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary F1RWN4 UniProtKB/Swiss-Prot