Memo1 (mediator of cell motility 1) - Rat Genome Database
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Gene: Memo1 (mediator of cell motility 1) Mus musculus
Analyze
Symbol: Memo1
Name: mediator of cell motility 1
RGD ID: 1552554
MGI Page MGI
Description: Predicted to have peptide binding activity. Predicted to be involved in regulation of microtubule-based process. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human MEMO1 (mediator of cell motility 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610016J10Rik; D930048L02Rik; mediator of ErbB2-driven cell motility 1; memo-1; protein memo
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm11708   Gm18382   Gm18385   Gm18409  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391774,493,759 - 74,602,677 (-)NCBIGRCm39mm39
GRCm381774,186,764 - 74,295,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1774,199,036 - 74,295,521 (-)EnsemblGRCm38mm10GRCm38
MGSCv371774,600,040 - 74,694,203 (-)NCBIGRCm37mm9NCBIm37
MGSCv361774,105,655 - 74,199,965 (-)NCBImm8
Celera1778,495,588 - 78,553,414 (-)NCBICelera
Cytogenetic Map17E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14681479   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:17077023   PMID:17967808   PMID:18045866   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:24056085   PMID:24714781   PMID:24917593   PMID:26746790  
PMID:27113764   PMID:27626380   PMID:29180744   PMID:29578408   PMID:30038585   PMID:31277925   PMID:32325033   PMID:32706793  


Genomics

Comparative Map Data
Memo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391774,493,759 - 74,602,677 (-)NCBIGRCm39mm39
GRCm381774,186,764 - 74,295,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1774,199,036 - 74,295,521 (-)EnsemblGRCm38mm10GRCm38
MGSCv371774,600,040 - 74,694,203 (-)NCBIGRCm37mm9NCBIm37
MGSCv361774,105,655 - 74,199,965 (-)NCBImm8
Celera1778,495,588 - 78,553,414 (-)NCBICelera
Cytogenetic Map17E2NCBI
MEMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl231,865,060 - 32,011,230 (-)EnsemblGRCh38hg38GRCh38
GRCh38231,867,188 - 32,011,008 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37232,092,892 - 32,236,116 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36231,946,396 - 32,089,202 (-)NCBINCBI36hg18NCBI36
Build 34232,004,546 - 32,147,349NCBI
Celera231,937,749 - 32,080,568 (-)NCBI
Cytogenetic Map2p22.3NCBI
HuRef231,832,452 - 31,923,497 (-)NCBIHuRef
CHM1_1232,022,699 - 32,166,291 (-)NCBICHM1_1
Memo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0622,362,483 - 22,409,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl622,362,484 - 22,409,579 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0632,248,023 - 32,295,278 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4621,149,520 - 21,197,328 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1621,152,474 - 21,200,281 (+)NCBI
Celera620,744,198 - 20,791,297 (+)NCBICelera
Cytogenetic Map6q13NCBI
Memo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955441332,864 - 391,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955441332,864 - 391,836 (-)NCBIChiLan1.0ChiLan1.0
MEMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A31,956,294 - 32,098,889 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A31,956,831 - 32,051,337 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A31,887,899 - 32,032,155 (-)NCBIMhudiblu_PPA_v0panPan3
MEMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1725,237,661 - 25,303,462 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11725,231,982 - 25,298,786 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Memo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364931,396,106 - 1,506,716 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3107,542,095 - 107,658,455 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13107,542,045 - 107,657,195 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23114,306,301 - 114,420,268 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEMO1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11475,480,890 - 75,625,264 (+)NCBI
ChlSab1.1 Ensembl1475,557,793 - 75,627,858 (+)Ensembl
Memo1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473813,575,542 - 13,687,002 (-)NCBI

Position Markers
AA990452  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381774,248,184 - 74,248,322UniSTSGRCm38
MGSCv371774,647,524 - 74,647,662UniSTSGRCm37
Celera1778,543,095 - 78,543,233UniSTS
Cytogenetic Map17E2UniSTS
Whitehead/MRC_RH17872.02UniSTS
D17Mit38  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381774,282,094 - 74,282,202UniSTSGRCm38
MGSCv371774,681,434 - 74,681,542UniSTSGRCm37
Celera1778,577,138 - 78,577,222UniSTS
Cytogenetic Map17E2UniSTS
cM Map1745.3UniSTS
Whitehead Genetic1740.4UniSTS
Whitehead/MRC_RH17870.0UniSTS
Whitehead_YAC17 UniSTS
0610016J10Rik  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17E2UniSTS
cM Map17 UniSTS
Memo1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17E2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4022744774227623Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174063218774632187Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174620000082100000Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined174989696283897108Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175145143085451617Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175145143085451617Mouse
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175680065690800808Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175680065690800808Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175680065690800808Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175680065690800808Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175680065690800808Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175680065690800808Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5722744780578347Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175722744793199751Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5728209491282202Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176199358194987271Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176199358194987271Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176357811994987271Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176490750994987271Mouse
14928308Manh82_mmandible shape 82 (mouse)176600781494987271Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176863389194987271Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177039377094987271Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177039377094987271Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177039377094987271Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177039377094987271Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177308770494987271Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177308770494987271Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7380065693199751Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177428209490087842Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177428209490087842Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:154
Count of miRNA genes:140
Interacting mature miRNAs:142
Transcripts:ENSMUST00000078459
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006525109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003952211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_385387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC169506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF363447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF466279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000078459   ⟹   ENSMUSP00000077553
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,200,702 - 74,294,790 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232861
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,254,675 - 74,255,985 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232987   ⟹   ENSMUSP00000156956
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,201,071 - 74,295,496 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232989   ⟹   ENSMUSP00000156437
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,200,702 - 74,294,801 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233144   ⟹   ENSMUSP00000156440
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,244,978 - 74,295,521 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233176   ⟹   ENSMUSP00000156929
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,200,718 - 74,294,799 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233214
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,252,628 - 74,294,841 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233422
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,200,702 - 74,288,648 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233495
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,201,116 - 74,230,501 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233514   ⟹   ENSMUSP00000156607
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1774,199,036 - 74,294,863 (-)Ensembl
RefSeq Acc Id: NM_133771   ⟹   NP_598532
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391774,507,695 - 74,601,858 (-)NCBI
GRCm381774,200,700 - 74,294,863 (-)NCBI
MGSCv371774,600,040 - 74,694,203 (-)RGD
Celera1778,495,588 - 78,553,414 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006525109   ⟹   XP_006525172
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391774,493,759 - 74,602,677 (-)NCBI
GRCm381774,200,700 - 74,295,682 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246713   ⟹   XP_011245015
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391774,493,759 - 74,602,571 (-)NCBI
GRCm381774,186,764 - 74,295,528 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160831   ⟹   XP_036016724
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391774,493,759 - 74,602,571 (-)NCBI
RefSeq Acc Id: XR_003952211
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391774,493,759 - 74,602,571 (-)NCBI
GRCm381774,186,764 - 74,295,532 (-)NCBI
Sequence:
RefSeq Acc Id: XR_385387
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391774,493,759 - 74,602,571 (-)NCBI
GRCm381774,186,764 - 74,295,533 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_598532   ⟸   NM_133771
- UniProtKB: Q91VH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006525172   ⟸   XM_006525109
- Peptide Label: isoform X1
- UniProtKB: Q91VH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011245015   ⟸   XM_011246713
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSMUSP00000156607   ⟸   ENSMUST00000233514
RefSeq Acc Id: ENSMUSP00000156929   ⟸   ENSMUST00000233176
RefSeq Acc Id: ENSMUSP00000156440   ⟸   ENSMUST00000233144
RefSeq Acc Id: ENSMUSP00000156437   ⟸   ENSMUST00000232989
RefSeq Acc Id: ENSMUSP00000156956   ⟸   ENSMUST00000232987
RefSeq Acc Id: ENSMUSP00000077553   ⟸   ENSMUST00000078459
RefSeq Acc Id: XP_036016724   ⟸   XM_036160831
- Peptide Label: isoform X2

Promoters
RGD ID:13676762
Promoter ID:EPDNEW_M22530
Type:initiation region
Name:Memo1_1
Description:Mus musculus mediator of cell motility 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381774,294,790 - 74,294,850EPDNEW
RGD ID:6828343
Promoter ID:MM_KWN:24186
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000078459,   NM_133771
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361774,694,031 - 74,695,277 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924140 AgrOrtholog
Ensembl Genes ENSMUSG00000058704 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000077553 UniProtKB/TrEMBL
  ENSMUSP00000156437 UniProtKB/TrEMBL
  ENSMUSP00000156440 UniProtKB/TrEMBL
  ENSMUSP00000156607 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000156929 UniProtKB/TrEMBL
  ENSMUSP00000156956 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078459 UniProtKB/TrEMBL
  ENSMUST00000232987 UniProtKB/TrEMBL
  ENSMUST00000232989 UniProtKB/TrEMBL
  ENSMUST00000233144 UniProtKB/TrEMBL
  ENSMUST00000233176 UniProtKB/TrEMBL
  ENSMUST00000233514 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro MEMO1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:76890 UniProtKB/Swiss-Prot
MGD MGI:1924140 ENTREZGENE
NCBI Gene 76890 ENTREZGENE
PANTHER PTHR11060 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Memo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Memo1 PhenoGen
UniProt A0A3B2W4G7_MOUSE UniProtKB/TrEMBL
  A0A3B2W4I2_MOUSE UniProtKB/TrEMBL
  A0A3B2W7C9_MOUSE UniProtKB/TrEMBL
  A0A3B2WCC1_MOUSE UniProtKB/TrEMBL
  A0A3F2YNL8_MOUSE UniProtKB/TrEMBL
  MEMO1_MOUSE UniProtKB/Swiss-Prot
  Q3TWT2_MOUSE UniProtKB/TrEMBL
  Q91VH6 ENTREZGENE