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Gene: Rffl (ring finger and FYVE like domain containing protein) Mus musculus
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Symbol: Rffl
Name: ring finger and FYVE like domain containing protein
RGD ID: 1552495
Description: Predicted to have enzyme binding activity; p53 binding activity; and ubiquitin protein ligase activity. Involved in intracellular protein transport and regulation of fibroblast migration. Localizes to cytoplasmic vesicle. Is expressed in bladder; retina inner nuclear layer; retina outer nuclear layer; and ureter. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700051E09Rik; 4930516L10Rik; BG080975; Ca; Car; Carp2; E3 ubiquitin-protein ligase rififylin; fr; fring; MGC144763; rif; rififylin; RING finger and FYVE-like domain-containing protein 1; RING-type E3 ubiquitin transferase rififylin
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,694,645 - 82,762,065 (-)NCBI
GRCm381182,803,819 - 82,871,236 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,802,449 - 82,871,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv371182,617,321 - 82,684,712 (-)NCBIGRCm37mm9NCBIm37
MGSCv361182,620,017 - 82,686,939 (-)NCBImm8
Celera1192,423,191 - 92,490,746 (-)NCBICelera
Cytogenetic Map11CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rffl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552495
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.