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Gene: Rnf146 (ring finger protein 146) Mus musculus
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Symbol: Rnf146
Name: ring finger protein 146
Description: Predicted to have poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to localize to the cytosol; nucleoplasm; and plasma membrane. Used to study cleidocranial dysplasia. Is expressed in genitourinary system. Orthologous to human RNF146 (ring finger protein 146); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610509H23Rik; E3 ubiquitin-protein ligase RNF146; Iduna; RING-type E3 ubiquitin transferase RNF146
Orthologs:
Homo sapiens (human) : RNF146 (ring finger protein 146)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rnf146 (ring finger protein 146)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf146 (ring finger protein 146)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF146 (ring finger protein 146)
Canis lupus familiaris (dog) : RNF146 (ring finger protein 146)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf146 (ring finger protein 146)
Sus scrofa (pig) : RNF146 (ring finger protein 146)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381029,344,176 - 29,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371029,063,982 - 29,082,248 (-)NCBIGRCm37mm9NCBIm37
MGSCv361029,035,587 - 29,051,858 (-)NCBImm8
Celera1030,276,585 - 30,294,697 (-)NCBICelera
Cytogenetic Map10 A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rnf146
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552458
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.