Rnf146 (ring finger protein 146) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rnf146 (ring finger protein 146) Mus musculus
Analyze
Symbol: Rnf146
Name: ring finger protein 146
RGD ID: 1552458
MGI Page MGI
Description: Predicted to enable enzyme binding activity; poly-ADP-D-ribose binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular response to hydrogen peroxide; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system and genitourinary system. Used to study osteochondrodysplasia. Orthologous to human RNF146 (ring finger protein 146).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610509H23Rik; E3 ubiquitin-protein ligase RNF146; Id; Iduna; RING-type E3 ubiquitin transferase RNF146
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391029,220,172 - 29,238,438 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1029,220,172 - 29,238,438 (-)EnsemblGRCm39 Ensembl
GRCm381029,344,176 - 29,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1029,344,176 - 29,362,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv371029,063,982 - 29,082,248 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361029,035,587 - 29,051,858 (-)NCBIMGSCv36mm8
Celera1030,276,585 - 30,294,697 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IBA)
plasma membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal alveolar process morphology  (IAGP)
abnormal ameloblast differentiation  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal endochondral bone ossification  (IAGP)
abnormal intramembranous bone ossification  (IAGP)
abnormal limb long bone morphology  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal rib morphology  (IAGP)
clavicle hypoplasia  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone mineralization  (IAGP)
decreased bone ossification  (IAGP)
decreased bone trabecula number  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating osteocalcin level  (IAGP)
decreased compact bone thickness  (IAGP)
decreased compact bone volume  (IAGP)
decreased insulin secretion  (IAGP)
decreased osteoblast cell number  (IAGP)
decreased osteoblast proliferation  (IAGP)
decreased pancreatic islet number  (IAGP)
decreased trabecular bone mass  (IAGP)
decreased trabecular bone volume  (IAGP)
impaired glucose tolerance  (IAGP)
impaired osteoblast differentiation  (IAGP)
increased bone marrow adipose tissue amount  (IAGP)
increased bone trabecular spacing  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased osteoclast cell number  (IAGP)
increased total body fat amount  (IAGP)
large anterior fontanelle  (IAGP)
large posterior fontanelle  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
respiratory distress  (IAGP)
small pancreatic islets  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation. Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia-ischemia. Yang X, etal., Neuroscience. 2017 Mar 27;346:74-80. doi: 10.1016/j.neuroscience.2017.01.010. Epub 2017 Jan 17.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12819125   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17609113  
PMID:17967808   PMID:18287559   PMID:18799693   PMID:21267068   PMID:21825151   PMID:21873635   PMID:22988430   PMID:23333241   PMID:24842055   PMID:25327252   PMID:27521426   PMID:28287403  
PMID:28581440   PMID:30783098   PMID:30974833   PMID:31472117   PMID:34856161   PMID:37524878   PMID:38272024  


Genomics

Comparative Map Data
Rnf146
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391029,220,172 - 29,238,438 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1029,220,172 - 29,238,438 (-)EnsemblGRCm39 Ensembl
GRCm381029,344,176 - 29,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1029,344,176 - 29,362,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv371029,063,982 - 29,082,248 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361029,035,587 - 29,051,858 (-)NCBIMGSCv36mm8
Celera1030,276,585 - 30,294,697 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.6NCBI
RNF146
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,266,682 - 127,288,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,266,726 - 127,288,567 (+)EnsemblGRCh38hg38GRCh38
GRCh376127,587,827 - 127,609,707 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366127,629,713 - 127,651,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 346127,629,712 - 127,651,198NCBI
Celera6128,330,302 - 128,351,791 (+)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,164,466 - 125,186,349 (+)NCBIHuRef
CHM1_16127,852,150 - 127,874,042 (+)NCBICHM1_1
T2T-CHM13v2.06128,455,637 - 128,477,520 (+)NCBIT2T-CHM13v2.0
Rnf146
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,286,680 - 30,304,367 (+)NCBIGRCr8
mRatBN7.2128,458,864 - 28,475,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,458,887 - 28,475,923 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,260,504 - 28,271,097 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,260,355 - 34,270,948 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0128,461,120 - 28,471,713 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0130,856,923 - 30,873,814 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl130,863,217 - 30,873,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0132,290,907 - 32,307,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,255,138 - 29,265,731 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,258,082 - 29,268,670 (+)NCBI
Celera127,132,709 - 27,143,302 (+)NCBICelera
Cytogenetic Map1p11NCBI
Rnf146
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554368,312,096 - 8,331,648 (+)NCBIChiLan1.0ChiLan1.0
RNF146
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,263,264 - 147,284,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,172,033 - 145,193,592 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06125,057,312 - 125,079,096 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,170,440 - 129,192,602 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6129,190,562 - 129,191,733 (+)Ensemblpanpan1.1panPan2
RNF146
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,988,600 - 66,010,873 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,988,656 - 66,010,881 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha166,794,457 - 66,816,710 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,191,606 - 66,213,917 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,191,010 - 66,213,917 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,121,749 - 66,143,998 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,906,358 - 65,928,595 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,548,694 - 66,570,938 (+)NCBIUU_Cfam_GSD_1.0
Rnf146
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946116,001,734 - 116,023,924 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366392,393,150 - 2,417,982 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366392,394,566 - 2,417,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF146
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl135,909,575 - 35,926,968 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1135,909,789 - 35,927,265 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2139,594,042 - 39,612,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF146
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11346,441,069 - 46,462,533 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1346,441,741 - 46,442,823 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf146
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247531,671,614 - 1,706,793 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf146
654 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1096
Count of miRNA genes:531
Interacting mature miRNAs:610
Transcripts:ENSMUST00000037548, ENSMUST00000160144, ENSMUST00000160372, ENSMUST00000161508, ENSMUST00000162335
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10440815438408276Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
1558857Igan1_mIgA nephropathy 1 (mouse)Not determined101771831329704155Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102689026446720483Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
AI314462  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381029,345,767 - 29,345,909UniSTSGRCm38
MGSCv371029,065,573 - 29,065,715UniSTSGRCm37
Celera1030,278,176 - 30,278,318UniSTS
Cytogenetic Map10A4UniSTS
cM Map1022.0UniSTS
Whitehead/MRC_RH10345.71UniSTS
Whitehead/MRC_RH10338.36UniSTS
BF389128  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381029,357,725 - 29,357,871UniSTSGRCm38
MGSCv371029,077,531 - 29,077,677UniSTSGRCm37
Celera1030,290,134 - 30,290,280UniSTS
Cytogenetic Map10A4UniSTS
AU015485  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381029,345,715 - 29,345,938UniSTSGRCm38
MGSCv371029,065,521 - 29,065,744UniSTSGRCm37
Celera1030,278,124 - 30,278,347UniSTS
Cytogenetic Map10A4UniSTS
cM Map1022.0UniSTS
Whitehead/MRC_RH10345.36UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001110196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001110197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001110198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001284279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_026518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC153912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF461810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ713250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU562186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY787516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000037548   ⟹   ENSMUSP00000037224
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1029,220,174 - 29,238,438 (-)Ensembl
GRCm38.p6 Ensembl1029,344,178 - 29,362,442 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160144   ⟹   ENSMUSP00000124288
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1029,220,172 - 29,238,438 (-)Ensembl
GRCm38.p6 Ensembl1029,344,176 - 29,362,442 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160372   ⟹   ENSMUSP00000124215
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1029,222,172 - 29,238,043 (-)Ensembl
GRCm38.p6 Ensembl1029,346,176 - 29,362,047 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161508   ⟹   ENSMUSP00000124814
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1029,223,215 - 29,238,022 (-)Ensembl
GRCm38.p6 Ensembl1029,347,219 - 29,362,026 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162335   ⟹   ENSMUSP00000124772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1029,222,654 - 29,233,709 (-)Ensembl
GRCm38.p6 Ensembl1029,346,658 - 29,357,713 (-)Ensembl
Ensembl Acc Id: ENSMUST00000214896   ⟹   ENSMUSP00000149976
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1029,223,380 - 29,238,043 (-)Ensembl
GRCm38.p6 Ensembl1029,347,384 - 29,362,047 (-)Ensembl
RefSeq Acc Id: NM_001110196   ⟹   NP_001103666
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391029,220,172 - 29,238,438 (-)NCBI
GRCm381029,344,176 - 29,362,442 (-)ENTREZGENE
MGSCv371029,063,982 - 29,082,248 (-)RGD
Celera1030,276,585 - 30,294,697 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001110197   ⟹   NP_001103667
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391029,220,172 - 29,238,438 (-)NCBI
GRCm381029,344,176 - 29,362,442 (-)ENTREZGENE
MGSCv371029,063,982 - 29,082,248 (-)RGD
Celera1030,276,585 - 30,294,697 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001110198   ⟹   NP_001103668
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391029,220,172 - 29,238,438 (-)NCBI
GRCm381029,344,176 - 29,362,442 (-)ENTREZGENE
MGSCv371029,063,982 - 29,082,248 (-)RGD
Celera1030,276,585 - 30,294,697 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001284279   ⟹   NP_001271208
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391029,220,172 - 29,233,709 (-)NCBI
GRCm381029,344,176 - 29,357,713 (-)NCBI
Celera1030,276,585 - 30,294,697 (-)NCBI
Sequence:
RefSeq Acc Id: NM_026518   ⟹   NP_080794
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391029,220,172 - 29,238,438 (-)NCBI
GRCm381029,344,176 - 29,362,442 (-)ENTREZGENE
MGSCv371029,063,982 - 29,082,248 (-)RGD
Celera1030,276,585 - 30,294,697 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_080794   ⟸   NM_026518
- UniProtKB: Q3TF93 (UniProtKB/Swiss-Prot),   E0CX97 (UniProtKB/Swiss-Prot),   Q3U6Y7 (UniProtKB/Swiss-Prot),   Q9CZW6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001103666   ⟸   NM_001110196
- UniProtKB: Q3TF93 (UniProtKB/Swiss-Prot),   E0CX97 (UniProtKB/Swiss-Prot),   Q3U6Y7 (UniProtKB/Swiss-Prot),   Q9CZW6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001103667   ⟸   NM_001110197
- UniProtKB: Q3TF93 (UniProtKB/Swiss-Prot),   E0CX97 (UniProtKB/Swiss-Prot),   Q3U6Y7 (UniProtKB/Swiss-Prot),   Q9CZW6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001103668   ⟸   NM_001110198
- UniProtKB: Q3TF93 (UniProtKB/Swiss-Prot),   E0CX97 (UniProtKB/Swiss-Prot),   Q3U6Y7 (UniProtKB/Swiss-Prot),   Q9CZW6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001271208   ⟸   NM_001284279
- UniProtKB: Q3TF93 (UniProtKB/Swiss-Prot),   E0CX97 (UniProtKB/Swiss-Prot),   Q3U6Y7 (UniProtKB/Swiss-Prot),   Q9CZW6 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000124288   ⟸   ENSMUST00000160144
Ensembl Acc Id: ENSMUSP00000037224   ⟸   ENSMUST00000037548
Ensembl Acc Id: ENSMUSP00000124215   ⟸   ENSMUST00000160372
Ensembl Acc Id: ENSMUSP00000124772   ⟸   ENSMUST00000162335
Ensembl Acc Id: ENSMUSP00000124814   ⟸   ENSMUST00000161508
Ensembl Acc Id: ENSMUSP00000149976   ⟸   ENSMUST00000214896
Protein Domains
RING-type   WWE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CZW6-F1-model_v2 AlphaFold Q9CZW6 1-359 view protein structure

Promoters
RGD ID:6819811
Promoter ID:MM_KWN:3828
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Brain,   Kidney,   Liver
Transcripts:ENSMUST00000037548
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361029,066,736 - 29,068,337 (-)MPROMDB
RGD ID:6819813
Promoter ID:MM_KWN:3830
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:OTTMUST00000069491
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361029,077,361 - 29,077,861 (-)MPROMDB
RGD ID:6819812
Promoter ID:MM_KWN:3831
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001110196,   NM_001110197,   NM_001110198,   NM_026518
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361029,081,646 - 29,082,146 (-)MPROMDB
RGD ID:8671726
Promoter ID:EPDNEW_M13894
Type:single initiation site
Name:Rnf146_2
Description:Mus musculus ring finger protein 146 , transcript variant 4,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13895  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381029,357,711 - 29,357,771EPDNEW
RGD ID:8671728
Promoter ID:EPDNEW_M13895
Type:initiation region
Name:Rnf146_1
Description:Mus musculus ring finger protein 146 , transcript variant 4,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13894  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381029,362,043 - 29,362,103EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915281 AgrOrtholog
Ensembl Genes ENSMUSG00000038876 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037548 ENTREZGENE
  ENSMUST00000037548.11 UniProtKB/Swiss-Prot
  ENSMUST00000160144 ENTREZGENE
  ENSMUST00000160144.9 UniProtKB/Swiss-Prot
  ENSMUST00000160372 ENTREZGENE
  ENSMUST00000160372.9 UniProtKB/Swiss-Prot
  ENSMUST00000161508.3 UniProtKB/TrEMBL
  ENSMUST00000162335 ENTREZGENE
  ENSMUST00000162335.8 UniProtKB/Swiss-Prot
  ENSMUST00000214896.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.720.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RING-HC_RNF146 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNF146 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WWE-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WWE-dom_subgr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1915281 ENTREZGENE
NCBI Gene 68031 ENTREZGENE
PANTHER PTHR13417:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WWE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf146 PhenoGen
PROSITE WWE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WWE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF117839 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SSN4_MOUSE UniProtKB/TrEMBL
  E0CX97 ENTREZGENE
  H9KV17_MOUSE UniProtKB/TrEMBL
  Q3TF93 ENTREZGENE
  Q3U6Y7 ENTREZGENE
  Q9CTK2_MOUSE UniProtKB/TrEMBL
  Q9CTM5_MOUSE UniProtKB/TrEMBL
  Q9CZW6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary E0CX97 UniProtKB/Swiss-Prot
  Q3TF93 UniProtKB/Swiss-Prot
  Q3U6Y7 UniProtKB/Swiss-Prot