Pde8b (phosphodiesterase 8B) - Rat Genome Database

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Gene: Pde8b (phosphodiesterase 8B) Mus musculus
Analyze
Symbol: Pde8b
Name: phosphodiesterase 8B
RGD ID: 1552413
MGI Page MGI
Description: Enables 3',5'-cyclic-AMP phosphodiesterase activity. Acts upstream of or within several processes, including behavioral fear response; learning; and negative regulation of steroid hormone biosynthetic process. Is expressed in several structures, including alimentary system; central nervous system; hindlimb digit; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Orthologous to human PDE8B (phosphodiesterase 8B); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B230331L10Rik; C030047E14Rik; cell proliferation-inducing gene 22 protein; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391395,160,613 - 95,386,904 (-)NCBIGRCm39mm39
GRCm39 Ensembl1395,160,962 - 95,386,844 (-)Ensembl
GRCm381395,024,105 - 95,250,401 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1395,024,454 - 95,250,336 (-)EnsemblGRCm38mm10GRCm38
MGSCv371395,794,060 - 96,020,259 (-)NCBIGRCm37mm9NCBIm37
MGSCv361396,125,209 - 96,356,676 (-)NCBImm8
Celera1398,642,301 - 98,869,729 (-)NCBICelera
Cytogenetic Map13D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14681479   PMID:16141072   PMID:16141073   PMID:17307970   PMID:21187369   PMID:21267068   PMID:21317369  
PMID:21677750   PMID:21873635   PMID:22232524   PMID:22925203   PMID:27277803   PMID:33338547  


Genomics

Comparative Map Data
Pde8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391395,160,613 - 95,386,904 (-)NCBIGRCm39mm39
GRCm39 Ensembl1395,160,962 - 95,386,844 (-)Ensembl
GRCm381395,024,105 - 95,250,401 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1395,024,454 - 95,250,336 (-)EnsemblGRCm38mm10GRCm38
MGSCv371395,794,060 - 96,020,259 (-)NCBIGRCm37mm9NCBIm37
MGSCv361396,125,209 - 96,356,676 (-)NCBImm8
Celera1398,642,301 - 98,869,729 (-)NCBICelera
Cytogenetic Map13D1NCBI
PDE8B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl577,210,449 - 77,428,256 (+)EnsemblGRCh38hg38GRCh38
GRCh38577,180,304 - 77,428,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37576,476,129 - 76,724,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36576,542,462 - 76,758,999 (+)NCBINCBI36hg18NCBI36
Build 34576,542,461 - 76,758,982NCBI
Celera572,400,947 - 72,618,614 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef571,713,174 - 71,930,868 (+)NCBIHuRef
CHM1_1575,940,448 - 76,157,815 (+)NCBICHM1_1
Pde8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2226,275,117 - 26,479,725 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl224,719,976 - 24,923,128 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0224,718,548 - 24,955,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0243,877,817 - 44,112,405 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4225,352,725 - 25,469,209 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1225,273,093 - 25,389,578 (-)NCBI
Celera222,346,017 - 22,449,253 (-)NCBICelera
Cytogenetic Map2q12NCBI
Pde8b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542523,512,865 - 23,614,326 (-)NCBIChiLan1.0ChiLan1.0
PDE8B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1538,401,194 - 38,617,737 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0537,874,089 - 38,121,322 (-)NCBIMhudiblu_PPA_v0panPan3
PDE8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1329,289,867 - 29,432,557 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl329,291,549 - 29,432,542 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha330,529,732 - 30,795,035 (-)NCBI
ROS_Cfam_1.0329,211,247 - 29,477,045 (-)NCBI
UMICH_Zoey_3.1329,145,547 - 29,411,320 (-)NCBI
UNSW_CanFamBas_1.0329,126,263 - 29,366,339 (-)NCBI
UU_Cfam_GSD_1.0329,457,265 - 29,761,295 (-)NCBI
Pde8b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213185,408,778 - 185,646,290 (-)NCBI
SpeTri2.0NW_0049365495,212,693 - 5,450,195 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDE8B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1286,007,190 - 86,323,796 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2287,703,295 - 87,929,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDE8B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1471,425,722 - 71,668,747 (+)NCBI
Vero_WHO_p1.0NW_02366604920,170,235 - 20,506,517 (+)NCBI
Pde8b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248691,695,362 - 1,936,097 (+)NCBI

Position Markers
BB359354  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,220,386 - 95,220,528UniSTSGRCm38
MGSCv371395,990,341 - 95,990,483UniSTSGRCm37
Celera1398,839,704 - 98,839,846UniSTS
Cytogenetic Map13D1UniSTS
Whitehead/MRC_RH13827.7UniSTS
MHAa22e7.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,040,132 - 95,040,303UniSTSGRCm38
MGSCv371395,810,087 - 95,810,258UniSTSGRCm37
Celera1398,658,329 - 98,658,500UniSTS
Cytogenetic Map13D1UniSTS
Whitehead_YAC13 UniSTS
D13Mit160  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381395,197,866 - 95,198,129UniSTSGRCm38
MGSCv371395,967,821 - 95,968,084UniSTSGRCm37
Celera1398,816,385 - 98,816,648UniSTS
Cytogenetic Map13D1UniSTS
cM Map1349.0UniSTS
Whitehead Genetic1335.0UniSTS
Whitehead/MRC_RH13827.7UniSTS
Whitehead_YAC13 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136410270298102826Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368068947102068947Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1377900000111900000Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135648143696102654Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87753866112294569Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393738733120421639Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386205109120205250Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366596482100596627Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391828769120421639Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1369963165103963165Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391247158120421639Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386000000120000000Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55572541112294569Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136410270298102826Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133587692596102654Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20293442112761890Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55572541112294569Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356322643105285678Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383739552117739748Mouse
1301610Dps1_mdelta power in slow-wave sleep 1 (mouse)Not determined137704774395594386Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379102537113102654Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394391865120421639Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1367905880101906000Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55572541112294569Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1394900290120421639Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined75984481112294569Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55572541112294569Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382603460116603598Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2774
Count of miRNA genes:719
Interacting mature miRNAs:927
Transcripts:ENSMUST00000022192, ENSMUST00000067082, ENSMUST00000159598, ENSMUST00000159608, ENSMUST00000160412, ENSMUST00000160957, ENSMUST00000162153, ENSMUST00000162292, ENSMUST00000162328, ENSMUST00000162412, ENSMUST00000162670, ENSMUST00000162716, ENSMUST00000162882, ENSMUST00000172104
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001170669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001346782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001374003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001374004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001374005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001374006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001374007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC147108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02122695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02122700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE860708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG695121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY244338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD806392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF644173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000022192   ⟹   ENSMUSP00000022192
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,026,120 - 95,222,813 (-)Ensembl
RefSeq Acc Id: ENSMUST00000067082   ⟹   ENSMUSP00000070465
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,026,120 - 95,222,813 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159598   ⟹   ENSMUSP00000124447
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,100,919 - 95,250,315 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159608   ⟹   ENSMUSP00000125191
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,033,946 - 95,223,555 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160412
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,043,468 - 95,053,018 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160957   ⟹   ENSMUSP00000125115
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,043,022 - 95,250,274 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162153   ⟹   ENSMUSP00000124704
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,026,103 - 95,250,274 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162292   ⟹   ENSMUSP00000124068
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,024,505 - 95,223,066 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162328
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,090,069 - 95,223,066 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162412   ⟹   ENSMUSP00000124409
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,024,454 - 95,250,336 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162670   ⟹   ENSMUSP00000125237
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,024,459 - 95,034,253 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162716
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,104,688 - 95,186,317 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162882
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,025,330 - 95,046,066 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172104   ⟹   ENSMUSP00000128987
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1395,026,120 - 95,222,813 (-)Ensembl
RefSeq Acc Id: NM_001170669   ⟹   NP_001164140
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,613 - 95,359,558 (-)NCBI
GRCm381395,024,105 - 95,223,050 (-)NCBI
MGSCv371395,794,060 - 96,020,259 (-)RGD
Celera1398,642,301 - 98,869,729 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001346782   ⟹   NP_001333711
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,613 - 95,386,844 (-)NCBI
GRCm381395,024,105 - 95,250,336 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001374003   ⟹   NP_001360932
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,962 - 95,359,600 (-)NCBI
GRCm381395,024,454 - 95,223,092 (-)NCBI
RefSeq Acc Id: NM_001374004   ⟹   NP_001360933
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,962 - 95,359,600 (-)NCBI
GRCm381395,024,454 - 95,223,092 (-)NCBI
RefSeq Acc Id: NM_001374005   ⟹   NP_001360934
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,962 - 95,386,797 (-)NCBI
GRCm381395,024,454 - 95,250,289 (-)NCBI
RefSeq Acc Id: NM_001374006   ⟹   NP_001360935
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,962 - 95,386,797 (-)NCBI
GRCm381395,024,454 - 95,250,289 (-)NCBI
RefSeq Acc Id: NM_001374007   ⟹   NP_001360936
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,962 - 95,386,797 (-)NCBI
GRCm381395,024,454 - 95,250,289 (-)NCBI
RefSeq Acc Id: NM_172263   ⟹   NP_758467
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,160,613 - 95,386,812 (-)NCBI
GRCm381395,024,105 - 95,250,304 (-)NCBI
MGSCv371395,794,060 - 96,020,259 (-)RGD
Celera1398,642,301 - 98,869,729 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517587   ⟹   XP_006517650
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,023 - 95,359,636 (-)NCBI
GRCm381395,024,503 - 95,223,126 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517588   ⟹   XP_006517651
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,023 - 95,359,636 (-)NCBI
GRCm381395,024,503 - 95,223,126 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517589   ⟹   XP_006517652
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,023 - 95,359,636 (-)NCBI
GRCm381395,024,503 - 95,223,126 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517591   ⟹   XP_006517654
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,273,939 (-)NCBI
GRCm381395,024,503 - 95,137,439 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517594   ⟹   XP_006517657
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,386,900 (-)NCBI
GRCm381395,024,503 - 95,250,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244649   ⟹   XP_011242951
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,386,900 (-)NCBI
GRCm381395,024,503 - 95,250,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244650   ⟹   XP_011242952
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,359,637 (-)NCBI
GRCm381395,024,503 - 95,223,127 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244651   ⟹   XP_011242953
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,235,744 (-)NCBI
GRCm381395,024,503 - 95,099,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315493   ⟹   XP_017170982
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,023 - 95,386,897 (-)NCBI
GRCm381395,024,503 - 95,250,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315494   ⟹   XP_017170983
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,235,744 (-)NCBI
GRCm381395,024,503 - 95,099,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247233   ⟹   XP_030103093
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,386,903 (-)NCBI
GRCm381395,024,503 - 95,250,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247234   ⟹   XP_030103094
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,359,636 (-)NCBI
GRCm381395,024,503 - 95,223,125 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247235   ⟹   XP_030103095
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,359,637 (-)NCBI
GRCm381395,024,503 - 95,223,128 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247236   ⟹   XP_030103096
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,386,904 (-)NCBI
GRCm381395,024,503 - 95,250,400 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036158017   ⟹   XP_036013910
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,386,901 (-)NCBI
RefSeq Acc Id: XM_036158018   ⟹   XP_036013911
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391395,161,011 - 95,244,353 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001164140 (Get FASTA)   NCBI Sequence Viewer  
  NP_001333711 (Get FASTA)   NCBI Sequence Viewer  
  NP_001360932 (Get FASTA)   NCBI Sequence Viewer  
  NP_001360933 (Get FASTA)   NCBI Sequence Viewer  
  NP_001360934 (Get FASTA)   NCBI Sequence Viewer  
  NP_001360935 (Get FASTA)   NCBI Sequence Viewer  
  NP_001360936 (Get FASTA)   NCBI Sequence Viewer  
  NP_758467 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517650 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517651 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517652 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517654 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517657 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242951 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242952 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242953 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170982 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170983 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103093 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103094 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103095 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103096 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013910 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013911 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH32286 (Get FASTA)   NCBI Sequence Viewer  
  ABR45646 (Get FASTA)   NCBI Sequence Viewer  
  BAC29302 (Get FASTA)   NCBI Sequence Viewer  
  BAC38791 (Get FASTA)   NCBI Sequence Viewer  
  BAE23616 (Get FASTA)   NCBI Sequence Viewer  
  BAE32379 (Get FASTA)   NCBI Sequence Viewer  
  E9Q4S1 (Get FASTA)   NCBI Sequence Viewer  
  EDL00910 (Get FASTA)   NCBI Sequence Viewer  
  EDL00911 (Get FASTA)   NCBI Sequence Viewer  
  EDL00912 (Get FASTA)   NCBI Sequence Viewer  
  EDL00913 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_758467   ⟸   NM_172263
- Peptide Label: isoform 2
- UniProtKB: E9PXX4 (UniProtKB/TrEMBL),   Q8BI47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001164140   ⟸   NM_001170669
- Peptide Label: isoform 1
- UniProtKB: E9PYP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517657   ⟸   XM_006517594
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006517651   ⟸   XM_006517588
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006517650   ⟸   XM_006517587
- Peptide Label: isoform X1
- UniProtKB: E9Q8J6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517652   ⟸   XM_006517589
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006517654   ⟸   XM_006517591
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_011242951   ⟸   XM_011244649
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_011242952   ⟸   XM_011244650
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_011242953   ⟸   XM_011244651
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_017170982   ⟸   XM_017315493
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017170983   ⟸   XM_017315494
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: NP_001333711   ⟸   NM_001346782
- Peptide Label: isoform 3
- UniProtKB: E9PX38 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030103093   ⟸   XM_030247233
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030103096   ⟸   XM_030247236
- Peptide Label: isoform X8
RefSeq Acc Id: XP_030103095   ⟸   XM_030247235
- Peptide Label: isoform X8
RefSeq Acc Id: XP_030103094   ⟸   XM_030247234
- Peptide Label: isoform X6
RefSeq Acc Id: NP_001360935   ⟸   NM_001374006
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001360934   ⟸   NM_001374005
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001360936   ⟸   NM_001374007
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001360933   ⟸   NM_001374004
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001360932   ⟸   NM_001374003
- Peptide Label: isoform 4
RefSeq Acc Id: ENSMUSP00000124447   ⟸   ENSMUST00000159598
RefSeq Acc Id: ENSMUSP00000125191   ⟸   ENSMUST00000159608
RefSeq Acc Id: ENSMUSP00000128987   ⟸   ENSMUST00000172104
RefSeq Acc Id: ENSMUSP00000070465   ⟸   ENSMUST00000067082
RefSeq Acc Id: ENSMUSP00000125115   ⟸   ENSMUST00000160957
RefSeq Acc Id: ENSMUSP00000022192   ⟸   ENSMUST00000022192
RefSeq Acc Id: ENSMUSP00000125237   ⟸   ENSMUST00000162670
RefSeq Acc Id: ENSMUSP00000124704   ⟸   ENSMUST00000162153
RefSeq Acc Id: ENSMUSP00000124068   ⟸   ENSMUST00000162292
RefSeq Acc Id: ENSMUSP00000124409   ⟸   ENSMUST00000162412
RefSeq Acc Id: XP_036013910   ⟸   XM_036158017
- Peptide Label: isoform X10
RefSeq Acc Id: XP_036013911   ⟸   XM_036158018
- Peptide Label: isoform X11
Protein Domains
PAS   PDEase

Promoters
RGD ID:8681040
Promoter ID:EPDNEW_M18551
Type:initiation region
Name:Pde8b_1
Description:Mus musculus phosphodiesterase 8B , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18552  EPDNEW_M18553  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381395,034,304 - 95,034,364EPDNEW
RGD ID:8681042
Promoter ID:EPDNEW_M18552
Type:initiation region
Name:Pde8b_2
Description:Mus musculus phosphodiesterase 8B , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18551  EPDNEW_M18553  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381395,222,964 - 95,223,024EPDNEW
RGD ID:8681044
Promoter ID:EPDNEW_M18553
Type:single initiation site
Name:Pde8b_3
Description:Mus musculus phosphodiesterase 8B , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18551  EPDNEW_M18552  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381395,223,457 - 95,223,517EPDNEW
RGD ID:6824231
Promoter ID:MM_KWN:14945
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:OTTMUST00000080934
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361395,804,161 - 95,804,972 (-)MPROMDB
RGD ID:6824251
Promoter ID:MM_KWN:14951
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:AK047680_C030010F05RIK,   ENSMUST00000067093,   OTTMUST00000080917,   OTTMUST00000080918,   OTTMUST00000080919,   UC007RME.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361395,992,526 - 95,993,026 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2443999 AgrOrtholog
Ensembl Genes ENSMUSG00000021684 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000022192 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000070465 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000124068 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124409 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124447 UniProtKB/TrEMBL
  ENSMUSP00000124704 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000125115 UniProtKB/TrEMBL
  ENSMUSP00000125191 UniProtKB/TrEMBL
  ENSMUSP00000125237 UniProtKB/TrEMBL
  ENSMUSP00000128987 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022192 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000067082 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000159598 UniProtKB/TrEMBL
  ENSMUST00000159608 UniProtKB/TrEMBL
  ENSMUST00000160957 UniProtKB/TrEMBL
  ENSMUST00000162153 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000162292 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000162412 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000162670 UniProtKB/TrEMBL
  ENSMUST00000172104 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.1300.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CheY-like_superfamily UniProtKB/TrEMBL
  HD/PDEase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEase_catalytic_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEase_catalytic_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEase_PDE8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:218461 UniProtKB/TrEMBL
MGD MGI:2443999 ENTREZGENE
NCBI Gene 218461 ENTREZGENE
Pfam PAS_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDE8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEase_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pde8b PhenoGen
PRINTS PDIESTERASE1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEASE_I_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDEASE_I_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52172 UniProtKB/TrEMBL
  SSF55785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs sensory_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6YR19_MOUSE UniProtKB/TrEMBL
  E0CXQ1_MOUSE UniProtKB/TrEMBL
  E0CY70_MOUSE UniProtKB/TrEMBL
  E9PUL4_MOUSE UniProtKB/TrEMBL
  E9PX38 ENTREZGENE, UniProtKB/TrEMBL
  E9PXX4 ENTREZGENE, UniProtKB/TrEMBL
  E9PYP0 ENTREZGENE, UniProtKB/TrEMBL
  E9Q4S1 ENTREZGENE
  E9Q7S6_MOUSE UniProtKB/TrEMBL
  E9Q8J6 ENTREZGENE, UniProtKB/TrEMBL
  F7CT85_MOUSE UniProtKB/TrEMBL
  PDE8B_MOUSE UniProtKB/Swiss-Prot
  Q3U4Q2_MOUSE UniProtKB/TrEMBL
  Q3UUK9_MOUSE UniProtKB/TrEMBL
  Q8BI47 ENTREZGENE, UniProtKB/TrEMBL
  Q8BIA0_MOUSE UniProtKB/TrEMBL
  Q8CFW8_MOUSE UniProtKB/TrEMBL