Cdc42bpg (CDC42 binding protein kinase gamma (DMPK-like)) - Rat Genome Database

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Gene: Cdc42bpg (CDC42 binding protein kinase gamma (DMPK-like)) Mus musculus
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Symbol: Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
RGD ID: 1552361
MGI Page MGI
Description: Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in actomyosin structure organization and peptidyl-threonine phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cell leading edge; centriolar satellite; and cytosol. Predicted to be active in cytoplasm and cytoskeleton. Orthologous to human CDC42BPG (CDC42 binding protein kinase gamma); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC046418; CDC42-binding protein kinase gamma; DMPK-like gamma; MRCK gamma; MRCKga; MRCKgamma; myotonic dystrophy kinase-related CDC42-binding kinase gamma; myotonic dystrophy protein kinase-like alpha; myotonic dystrophy protein kinase-like gamma; serine/threonine-protein kinase MRCK gamma
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,356,465 - 6,375,682 (+)NCBIGRCm39mm39
GRCm39 Ensembl196,356,486 - 6,375,682 (+)Ensembl
GRCm38196,306,253 - 6,325,653 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,306,456 - 6,325,652 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,306,457 - 6,325,652 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,306,448 - 6,324,573 (+)NCBImm8
Celera196,179,146 - 6,198,340 (+)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:15489334   PMID:15741177   PMID:16141072   PMID:16141073   PMID:19402746   PMID:21267068   PMID:21873635  
PMID:24457600   PMID:27256596   PMID:32325033  


Genomics

Comparative Map Data
Cdc42bpg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,356,465 - 6,375,682 (+)NCBIGRCm39mm39
GRCm39 Ensembl196,356,486 - 6,375,682 (+)Ensembl
GRCm38196,306,253 - 6,325,653 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,306,456 - 6,325,652 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,306,457 - 6,325,652 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,306,448 - 6,324,573 (+)NCBImm8
Celera196,179,146 - 6,198,340 (+)NCBICelera
Cytogenetic Map19ANCBI
CDC42BPG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1164,823,052 - 64,844,653 (-)EnsemblGRCh38hg38GRCh38
GRCh381164,823,052 - 64,844,686 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371164,590,524 - 64,612,125 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,348,237 - 64,368,617 (-)NCBINCBI36hg18NCBI36
Celera1161,917,813 - 61,938,195 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,918,707 - 60,939,096 (-)NCBIHuRef
CHM1_11164,475,451 - 64,495,843 (-)NCBICHM1_1
Cdc42bpg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21203,608,339 - 203,628,502 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1203,608,574 - 203,628,502 (+)Ensembl
Rnor_6.01221,673,334 - 221,693,518 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,673,590 - 221,693,518 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,661,352 - 228,681,281 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,083,957 - 209,103,885 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,242,641 - 209,270,023 (+)NCBI
Celera1201,142,065 - 201,161,993 (+)NCBICelera
Cytogenetic Map1q43NCBI
Cdc42bpg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,331,825 - 20,349,301 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,331,612 - 20,350,404 (+)NCBIChiLan1.0ChiLan1.0
CDC42BPG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11163,521,521 - 63,541,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,521,521 - 63,541,784 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01160,180,468 - 60,200,719 (-)NCBIMhudiblu_PPA_v0panPan3
CDC42BPG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,319,363 - 52,338,531 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1852,319,453 - 52,337,203 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,926,759 - 50,945,863 (+)NCBI
ROS_Cfam_1.01853,360,603 - 53,379,748 (+)NCBI
UMICH_Zoey_3.11852,455,576 - 52,474,707 (+)NCBI
UNSW_CanFamBas_1.01852,041,280 - 52,060,429 (+)NCBI
UU_Cfam_GSD_1.01852,825,526 - 52,844,736 (+)NCBI
Cdc42bpg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049478,039,803 - 8,055,898 (+)NCBI
SpeTri2.0NW_0049365994,481,774 - 4,498,247 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42BPG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,328,233 - 7,347,451 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,328,231 - 7,347,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,460,814 - 6,480,122 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42BPG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,390,874 - 9,411,503 (+)NCBI
ChlSab1.1 Ensembl19,390,825 - 9,412,697 (+)Ensembl
Vero_WHO_p1.0NW_023666038106,777,274 - 106,798,728 (+)NCBI
Cdc42bpg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476721,550,545 - 21,569,669 (+)NCBI

Position Markers
AW107720  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38196,325,315 - 6,325,437UniSTSGRCm38
MGSCv37196,325,315 - 6,325,437UniSTSGRCm37
Celera196,198,003 - 6,198,125UniSTS
Cytogenetic Map19AUniSTS
Whitehead/MRC_RH1941.96UniSTS
stSG635729  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38196,310,348 - 6,311,575UniSTSGRCm38
MGSCv37196,310,348 - 6,311,575UniSTSGRCm37
Celera196,183,037 - 6,184,264UniSTS
Cytogenetic Map19AUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120278703Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120645286Mouse
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122321310Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132362870Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132897810Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19167640035676563Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19320000035900000Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19327855120562299Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19334585237345984Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19334585237345984Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19334585237345984Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19334585237345984Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950147898980461Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19533596239336106Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:658
Count of miRNA genes:407
Interacting mature miRNAs:494
Transcripts:ENSMUST00000025681, ENSMUST00000141854
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000025681   ⟹   ENSMUSP00000025681
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl196,356,486 - 6,375,682 (+)Ensembl
GRCm38.p6 Ensembl196,306,456 - 6,325,652 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141854
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl196,371,838 - 6,372,262 (+)Ensembl
GRCm38.p6 Ensembl196,321,808 - 6,322,232 (+)Ensembl
RefSeq Acc Id: NM_001033342   ⟹   NP_001028514
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39196,356,487 - 6,375,682 (+)NCBI
GRCm38196,306,457 - 6,325,652 (+)NCBI
MGSCv37196,306,457 - 6,325,652 (+)RGD
Celera196,179,146 - 6,198,340 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036161588   ⟹   XP_036017481
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39196,356,465 - 6,375,681 (+)NCBI
RefSeq Acc Id: XM_036161589   ⟹   XP_036017482
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39196,356,465 - 6,375,681 (+)NCBI
RefSeq Acc Id: XM_036161590   ⟹   XP_036017483
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39196,356,465 - 6,370,367 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001028514   ⟸   NM_001033342
- UniProtKB: Q80UW5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000025681   ⟸   ENSMUST00000025681
RefSeq Acc Id: XP_036017481   ⟸   XM_036161588
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036017482   ⟸   XM_036161589
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036017483   ⟸   XM_036161590
- Peptide Label: isoform X3
Promoters
RGD ID:6829898
Promoter ID:MM_KWN:26174
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Lung,   MEF_B4
Transcripts:OTTMUST00000044838
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36196,306,236 - 6,306,887 (+)MPROMDB
RGD ID:13678658
Promoter ID:EPDNEW_M23478
Type:multiple initiation site
Name:Cdc42bpg_1
Description:Mus musculus CDC42 binding protein kinase gamma (DMPK-like) ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38196,306,546 - 6,306,606EPDNEW
RGD ID:6829900
Promoter ID:MM_KWN:26175
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:UC008GIA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36196,314,336 - 6,314,836 (+)MPROMDB
RGD ID:6847543
Promoter ID:MM_ACW:25902
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung,   Spleen
Transcripts:CDC42BPG.FSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36196,318,106 - 6,318,606 (+)MPROMDB
RGD ID:6829899
Promoter ID:MM_KWN:26176
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung
Transcripts:OTTMUST00000044839
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36196,320,886 - 6,322,117 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2652845 AgrOrtholog
Ensembl Genes ENSMUSG00000024769 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000025681 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000025681 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/Swiss-Prot
  CNH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIB_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  MRCK_gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myotonic_dystrophy_kinase_coil UniProtKB/Swiss-Prot
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report mmu:240505 UniProtKB/Swiss-Prot
MGD MGI:2652845 ENTREZGENE
NCBI Gene 240505 ENTREZGENE
PANTHER PTHR22988:SF22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot
  CNH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DMPK_coil UniProtKB/Swiss-Prot
  Pkinase UniProtKB/Swiss-Prot
  Pkinase_C UniProtKB/Swiss-Prot
PhenoGen Cdc42bpg PhenoGen
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot
  CNH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CNH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_TK_X UniProtKB/Swiss-Prot
  S_TKc UniProtKB/Swiss-Prot
  SM00109 UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt MRCKG_MOUSE UniProtKB/Swiss-Prot
  Q3V0F4_MOUSE UniProtKB/TrEMBL
  Q80UW5 ENTREZGENE