Arf5 (ADP-ribosylation factor 5) - Rat Genome Database

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Gene: Arf5 (ADP-ribosylation factor 5) Mus musculus
Analyze
Symbol: Arf5
Name: ADP-ribosylation factor 5
RGD ID: 1552329
MGI Page MGI
Description: Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to act upstream of or within protein transport. Located in cytoplasm and plasma membrane. Orthologous to human ARF5 (ADP ribosylation factor 5).
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39628,423,603 - 28,426,601 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl628,423,559 - 28,426,601 (+)EnsemblGRCm39 Ensembl
GRCm38628,423,604 - 28,426,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl628,423,560 - 28,426,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37628,373,640 - 28,376,499 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36628,373,650 - 28,376,509 (+)NCBIMGSCv36mm8
Celera628,430,700 - 28,433,539 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map611.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IDA)
Golgi apparatus  (IEA)
membrane  (IEA)
plasma membrane  (IBA,IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells. Schurmann A, etal., J Biol Chem 1994 Jun 3;269(22):15683-8.
Additional References at PubMed
PMID:8889548   PMID:8947846   PMID:12477932   PMID:16707424   PMID:20921225   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22111578   PMID:25737280   PMID:27507650   PMID:28378742  
PMID:28671696   PMID:28706196   PMID:29530978   PMID:30457570   PMID:30550785   PMID:31201232   PMID:32325033   PMID:36417873   PMID:37848288  


Genomics

Comparative Map Data
Arf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39628,423,603 - 28,426,601 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl628,423,559 - 28,426,601 (+)EnsemblGRCm39 Ensembl
GRCm38628,423,604 - 28,426,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl628,423,560 - 28,426,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37628,373,640 - 28,376,499 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36628,373,650 - 28,376,509 (+)NCBIMGSCv36mm8
Celera628,430,700 - 28,433,539 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map611.99NCBI
ARF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387127,588,411 - 127,591,700 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7127,588,386 - 127,591,700 (+)EnsemblGRCh38hg38GRCh38
GRCh377127,228,465 - 127,231,754 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367127,015,753 - 127,018,988 (+)NCBINCBI36Build 36hg18NCBI36
Build 347126,822,467 - 126,825,703NCBI
Celera7122,032,245 - 122,035,480 (+)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7121,589,476 - 121,592,829 (+)NCBIHuRef
CHM1_17127,161,703 - 127,165,056 (+)NCBICHM1_1
T2T-CHM13v2.07128,900,090 - 128,903,379 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27126,611,851 - 126,615,204 (+)NCBI
Arf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8458,003,919 - 58,006,898 (+)NCBIGRCr8
mRatBN7.2457,038,521 - 57,041,447 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl457,038,521 - 57,041,441 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx462,021,750 - 62,024,681 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0457,937,702 - 57,940,638 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0456,339,794 - 56,342,725 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0455,715,744 - 55,718,670 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl455,715,744 - 55,718,670 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0455,463,191 - 55,466,117 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4455,293,825 - 55,296,751 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1455,543,981 - 55,546,908 (+)NCBI
Celera452,150,105 - 52,153,031 (+)NCBICelera
Cytogenetic Map4q22NCBI
Arf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554798,644,658 - 8,647,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554798,644,658 - 8,647,697 (+)NCBIChiLan1.0ChiLan1.0
ARF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26164,447,503 - 164,450,855 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1716,457,764 - 16,461,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07119,583,955 - 119,587,272 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17132,239,114 - 132,242,323 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7132,239,114 - 132,242,323 (+)Ensemblpanpan1.1panPan2
ARF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,732,305 - 8,735,427 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,732,479 - 8,735,419 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,425,123 - 8,428,255 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0148,505,833 - 8,508,962 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,506,007 - 8,508,943 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,710,066 - 8,713,195 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,444,533 - 8,447,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,598,297 - 8,601,427 (-)NCBIUU_Cfam_GSD_1.0
Arf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511853,666,834 - 53,669,835 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647914,790,519 - 14,793,733 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647914,790,552 - 14,793,604 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1820,694,966 - 20,698,726 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11820,695,706 - 20,698,635 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21821,699,373 - 21,702,302 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12196,403,360 - 96,406,901 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2196,403,609 - 96,407,215 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660427,000,073 - 7,003,409 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247838,357,152 - 8,360,067 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247838,357,152 - 8,360,083 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arf5
71 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:531
Count of miRNA genes:303
Interacting mature miRNAs:339
Transcripts:ENSMUST00000020717, ENSMUST00000169841
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144495Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144495Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144495Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633435476334Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920638249325Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
11353836Bmiq1_mbody mass index QTL 1 (mouse)6450382329751333Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse

Markers in Region
RH129669  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38628,426,421 - 28,426,600UniSTSGRCm38
MGSCv37628,376,421 - 28,376,600UniSTSGRCm37
Celera628,433,461 - 28,433,640UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6A3UniSTS
SHGC-56778  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38628,421,060 - 28,421,200UniSTSGRCm38
MGSCv37628,371,060 - 28,371,200UniSTSGRCm37
Celera628,428,120 - 28,428,260UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6A3UniSTS
ARF5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38628,423,721 - 28,424,349UniSTSGRCm38
MGSCv37628,373,721 - 28,374,349UniSTSGRCm37
Cytogenetic Map6A3.3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000020717   ⟹   ENSMUSP00000020717
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl628,423,559 - 28,426,601 (+)Ensembl
GRCm38.p6 Ensembl628,423,560 - 28,426,602 (+)Ensembl
RefSeq Acc Id: ENSMUST00000169841   ⟹   ENSMUSP00000127281
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl628,423,589 - 28,426,345 (+)Ensembl
GRCm38.p6 Ensembl628,423,590 - 28,426,346 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202028
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl628,423,708 - 28,424,626 (+)Ensembl
GRCm38.p6 Ensembl628,423,709 - 28,424,627 (+)Ensembl
RefSeq Acc Id: NM_007480   ⟹   NP_031506
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39628,423,603 - 28,426,601 (+)NCBI
GRCm38628,423,604 - 28,426,602 (+)NCBI
MGSCv37628,373,640 - 28,376,499 (+)RGD
Celera628,430,700 - 28,433,539 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_031506 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI32453 (Get FASTA)   NCBI Sequence Viewer  
  AAI38757 (Get FASTA)   NCBI Sequence Viewer  
  BAA13494 (Get FASTA)   NCBI Sequence Viewer  
  EDL13803 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020717
  ENSMUSP00000020717.6
  ENSMUSP00000127281.2
GenBank Protein P84084 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_031506   ⟸   NM_007480
- UniProtKB: A2RTC5 (UniProtKB/Swiss-Prot),   P84084 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020717   ⟸   ENSMUST00000020717
RefSeq Acc Id: ENSMUSP00000127281   ⟸   ENSMUST00000169841

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P84084-F1-model_v2 AlphaFold P84084 1-180 view protein structure

Promoters
RGD ID:6838942
Promoter ID:MM_KWN:45338
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000050457
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36628,373,321 - 28,374,012 (+)MPROMDB
RGD ID:6889148
Promoter ID:EPDNEW_M8025
Type:initiation region
Name:Arf5_1
Description:Mus musculus ADP-ribosylation factor 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38628,423,604 - 28,423,664EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99434 AgrOrtholog
Ensembl Genes ENSMUSG00000020440 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020717 ENTREZGENE
  ENSMUST00000020717.12 UniProtKB/Swiss-Prot
  ENSMUST00000169841.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro Arf1_5_like UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase_ARF/SAR UniProtKB/Swiss-Prot
KEGG Report mmu:11844 UniProtKB/Swiss-Prot
MGD MGI:99434 ENTREZGENE
NCBI Gene 11844 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR 5 UniProtKB/Swiss-Prot
  PTHR11711 UniProtKB/Swiss-Prot
Pfam Arf UniProtKB/Swiss-Prot
PhenoGen Arf5 PhenoGen
PRINTS SAR1GTPBP UniProtKB/Swiss-Prot
PROSITE ARF UniProtKB/Swiss-Prot
SMART ARF UniProtKB/Swiss-Prot
  RAB UniProtKB/Swiss-Prot
  SAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A2RTC5 ENTREZGENE
  ARF5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A2RTC5 UniProtKB/Swiss-Prot
  P26437 UniProtKB/Swiss-Prot