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Gene: Ptprb (protein tyrosine phosphatase, receptor type, B) Mus musculus
Symbol: Ptprb
Name: protein tyrosine phosphatase, receptor type, B
RGD ID: 1552328
Description: Predicted to have cadherin binding activity. Involved in angiogenesis and peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity. Predicted to localize to receptor complex. Is expressed in several structures, including cardiovascular system; central nervous system; embryo mesenchyme; genitourinary system; and liver. Orthologous to human PTPRB (protein tyrosine phosphatase receptor type B); INTERACTS WITH 1,1-dichloroethene; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3230402H02Rik; C130094E24; protein-tyrosine phosphatase beta; Ptpz; R-PTP-beta; receptor-type tyrosine-protein phosphatase beta; Rptpb; vascular endothelial protein tyrosine phosphatase; VE-; VE-PTP; Veptp
Homo sapiens (human) : PTPRB (protein tyrosine phosphatase receptor type B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptprb (protein tyrosine phosphatase, receptor type, B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprb (protein tyrosine phosphatase receptor type B)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRB (protein tyrosine phosphatase receptor type B)
Canis lupus familiaris (dog) : PTPRB (protein tyrosine phosphatase receptor type B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprb (protein tyrosine phosphatase receptor type B)
Sus scrofa (pig) : PTPRB (protein tyrosine phosphatase receptor type B)
Chlorocebus sabaeus (African green monkey) : PTPRB (protein tyrosine phosphatase receptor type B)
Heterocephalus glaber (naked mole-rat) : Ptprb (protein tyrosine phosphatase receptor type B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910116,111,407 - 116,225,443 (+)NCBI
GRCm3810116,275,502 - 116,389,538 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10116,275,523 - 116,389,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710115,738,430 - 115,826,594 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610115,705,616 - 115,788,043 (+)NCBImm8
Celera10118,242,005 - 118,330,326 (+)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptprb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552328
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.