Symbol:
Tfdp2
Name:
transcription factor Dp 2
Description:
ENCODES a protein that exhibits DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein domain specific binding (ortholog); INVOLVED IN regulation of transcription, DNA-templated; negative regulation of transcription, DNA-templated (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ASSOCIATED WITH malignant mesothelioma (ortholog); FOUND IN mitotic spindle (ortholog); nucleoplasm (ortholog); RNA polymerase II transcription factor complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 3,3',5,5'-tetrabromobisphenol A
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
1110029I05Rik; A330080J22Rik; DP-3; DP3; E2F dimerization partner 2; RIKEN cDNA 1110029I05 gene; transcription factor Dp-2
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TFDP2 (transcription factor Dp-2) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):
Tfdp2 (transcription factor Dp-2) HGNC
EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Tfdp2 (transcription factor Dp-2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TFDP2 (transcription factor Dp-2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TFDP2 (transcription factor Dp-2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Tfdp2 (transcription factor Dp-2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TFDP2 (transcription factor Dp-2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Tfdp2 (transcription factor Dp-2)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER)
Homo sapiens (human):
TFDP2 (transcription factor Dp-2)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
tfdp2 (transcription factor Dp-2)
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam, ZFIN)
Caenorhabditis elegans (roundworm):
dpl-1
Alliance
DIOPT (Ensembl Compara, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup)
Drosophila melanogaster (fruit fly):
Dp
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 9 96,196,246 - 96,323,646 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 9 96,096,694 - 96,224,065 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 9 96,005,700 - 96,128,333 (+) NCBI mm8 Celera 9 95,752,654 - 95,877,737 (+) NCBI Celera Cytogenetic Map 9 E3.3 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1314075 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TFDP2 mRNA CTD PMID:22079256 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions ISO RGD:1305814 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of TFDP2 mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE decreases expression ISO RGD:1305814 6480464 Topotecan results in decreased expression of TFDP2 mRNA CTD PMID:25729387 17alpha-ethynylestradiol decreases expression ISO RGD:1314075 6480464 Ethinyl Estradiol results in decreased expression of TFDP2 mRNA CTD PMID:18936297 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of TFDP2 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1314075 6480464 Tetrachlorodibenzodioxin results in increased expression of TFDP2 mRNA CTD PMID:12377990 2-butoxyethanol increases expression EXP 6480464 n-butoxyethanol results in increased expression of TFDP2 mRNA CTD PMID:19812364 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of TFDP2 mRNA CTD PMID:25172293 4-hydroxynon-2-enal decreases expression ISO RGD:1314075 6480464 4-hydroxy-2-nonenal results in decreased expression of TFDP2 mRNA CTD PMID:12419474 aflatoxin B1 decreases methylation ISO RGD:1314075 6480464 Aflatoxin B1 results in decreased methylation of TFDP2 intron CTD PMID:30157460 aflatoxin B2 decreases methylation ISO RGD:1314075 6480464 aflatoxin B2 results in decreased methylation of TFDP2 intron CTD PMID:30157460 all-trans-retinoic acid decreases expression ISO RGD:1314075 6480464 Tretinoin results in decreased expression of TFDP2 mRNA CTD PMID:15498508 , PMID:16129123 arsane increases expression ISO RGD:1314075 6480464 Arsenic results in increased expression of TFDP2 mRNA CTD PMID:11134558 arsenic atom increases expression ISO RGD:1314075 6480464 Arsenic results in increased expression of TFDP2 mRNA CTD PMID:11134558 arsenic(3+) increases expression ISO RGD:1314075 6480464 Arsenic results in increased expression of TFDP2 mRNA CTD PMID:11134558 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of TFDP2 mRNA CTD PMID:21715664 benzo[a]pyrene affects methylation ISO RGD:1314075 6480464 Benzo(a)pyrene affects the methylation of TFDP2 intron CTD PMID:30157460 benzo[a]pyrene decreases expression ISO RGD:1314075 6480464 Benzo(a)pyrene results in decreased expression of TFDP2 mRNA CTD PMID:20106945 , PMID:21632981 benzo[e]pyrene decreases methylation ISO RGD:1314075 6480464 benzo(e)pyrene results in decreased methylation of TFDP2 intron CTD PMID:30157460 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TFDP2 mRNA CTD PMID:26063408 bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of TFDP2 promoter CTD PMID:27334623 bisphenol A affects expression ISO RGD:1305814 6480464 bisphenol A affects the expression of TFDP2 mRNA CTD PMID:25181051 cadmium dichloride increases expression ISO RGD:1314075 6480464 Cadmium Chloride results in increased expression of TFDP2 mRNA CTD PMID:12160620 , PMID:26472689 cadmium dichloride decreases expression ISO RGD:1305814 6480464 Cadmium Chloride results in decreased expression of TFDP2 mRNA CTD PMID:31077537 cadmium dichloride multiple interactions ISO RGD:1305814 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TFDP2 mRNA CTD PMID:31077537 calcitriol decreases expression ISO RGD:1314075 6480464 Calcitriol results in decreased expression of TFDP2 mRNA CTD PMID:16129123 carbon nanotube affects expression EXP 6480464 Nanotubes, Carbon affects the expression of TFDP2 mRNA, Nanotubes, Carbon analog affects the expression of TFDP2 mRNA CTD PMID:25554681 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon analog results in increased expression of TFDP2 mRNA CTD PMID:25620056 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TFDP2 mRNA CTD PMID:20938992 cisplatin decreases expression ISO RGD:1305814 6480464 Cisplatin results in decreased expression of TFDP2 mRNA CTD PMID:22023808 cisplatin decreases expression ISO RGD:1314075 6480464 Cisplatin results in decreased expression of TFDP2 mRNA CTD PMID:27594783 cobalt dichloride increases expression ISO RGD:1314075 6480464 cobaltous chloride results in increased expression of TFDP2 mRNA CTD PMID:19320972 cobalt dichloride decreases expression ISO RGD:1314075 6480464 cobaltous chloride results in decreased expression of TFDP2 mRNA CTD PMID:22941251 cocaine increases expression ISO RGD:1305814 6480464 Cocaine results in increased expression of TFDP2 mRNA CTD PMID:17898221 copper(II) chloride affects expression ISO RGD:1314075 6480464 cupric chloride affects the expression of TFDP2 mRNA CTD PMID:17211630 diallyl disulfide multiple interactions ISO RGD:1305814 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TFDP2 mRNA CTD PMID:31077537 diazinon affects expression ISO RGD:1305814 6480464 Diazinon affects the expression of TFDP2 mRNA CTD PMID:22546817 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of TFDP2 mRNA CTD PMID:17361019 , PMID:21266533 dieldrin affects expression ISO RGD:1305814 6480464 Dieldrin affects the expression of TFDP2 mRNA CTD PMID:22546817 diethylstilbestrol decreases expression ISO RGD:1305814 6480464 Diethylstilbestrol results in decreased expression of TFDP2 mRNA CTD PMID:21658437 dioxygen multiple interactions EXP 6480464 Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of TFDP2 mRNA] CTD PMID:22629407 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of TFDP2 mRNA CTD PMID:22629407 dorsomorphin multiple interactions ISO RGD:1314075 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of TFDP2 mRNA CTD PMID:25896364 endosulfan decreases expression ISO RGD:1305814 6480464 Endosulfan results in decreased expression of TFDP2 mRNA CTD PMID:29391264 entinostat decreases expression ISO RGD:1314075 6480464 entinostat results in decreased expression of TFDP2 mRNA CTD PMID:26272509 , PMID:27188386 entinostat multiple interactions ISO RGD:1314075 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TFDP2 mRNA CTD PMID:27188386 ethyl methanesulfonate increases expression ISO RGD:1314075 6480464 Ethyl Methanesulfonate results in increased expression of TFDP2 mRNA CTD PMID:23649840 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TFDP2 mRNA CTD PMID:20938992 formaldehyde increases expression ISO RGD:1314075 6480464 Formaldehyde results in increased expression of TFDP2 mRNA CTD PMID:23649840 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of TFDP2 mRNA CTD PMID:20003209 isotretinoin decreases expression ISO RGD:1314075 6480464 Isotretinoin results in decreased expression of TFDP2 mRNA CTD PMID:20436886 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TFDP2 mRNA CTD PMID:20938992 lead(0) affects expression ISO RGD:1314075 6480464 Lead affects the expression of TFDP2 mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:1314075 6480464 Lead affects the expression of TFDP2 mRNA CTD PMID:28903495 methapyrilene decreases methylation ISO RGD:1314075 6480464 Methapyrilene results in decreased methylation of TFDP2 intron CTD PMID:30157460 methylmercury chloride decreases expression ISO RGD:1314075 6480464 methylmercuric chloride results in decreased expression of TFDP2 mRNA CTD PMID:28001369 N(6)-dimethylallyladenine decreases expression ISO RGD:1314075 6480464 N(6)-(delta(2)-isopentenyl)adenine results in decreased expression of TFDP2 mRNA CTD PMID:16129123 nickel atom decreases expression ISO RGD:1314075 6480464 Nickel results in decreased expression of TFDP2 mRNA CTD PMID:24768652 , PMID:25583101 ochratoxin A multiple interactions ISO RGD:1314075 6480464 [ochratoxin A results in decreased acetylation of TFDP2 promoter] which results in decreased expression of TFDP2 mRNA CTD PMID:29098329 ochratoxin A decreases acetylation ISO RGD:1314075 6480464 ochratoxin A results in decreased acetylation of TFDP2 promoter CTD PMID:29098329 ochratoxin A decreases expression ISO RGD:1314075 6480464 ochratoxin A results in decreased expression of TFDP2 mRNA CTD PMID:29098329 oxaliplatin multiple interactions ISO RGD:1305814 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of TFDP2 mRNA CTD PMID:25729387 p-chloromercuribenzoic acid decreases expression ISO RGD:1314075 6480464 p-Chloromercuribenzoic Acid results in decreased expression of TFDP2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1314075 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TFDP2 mRNA CTD PMID:27188386 p-menthan-3-ol decreases expression ISO RGD:1314075 6480464 Menthol results in decreased expression of TFDP2 mRNA CTD PMID:26760959 phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of TFDP2 mRNA] CTD PMID:19482888 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of TFDP2 mRNA CTD PMID:19482888 phenylmercury acetate decreases expression ISO RGD:1314075 6480464 Phenylmercuric Acetate results in decreased expression of TFDP2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1314075 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TFDP2 mRNA CTD PMID:27188386 potassium chromate multiple interactions ISO RGD:1314075 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TFDP2 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1314075 6480464 potassium chromate(VI) results in decreased expression of TFDP2 mRNA CTD PMID:22079256 potassium dichromate affects expression EXP 6480464 Potassium Dichromate affects the expression of TFDP2 mRNA CTD PMID:23608068 quercetin decreases expression ISO RGD:1314075 6480464 Quercetin results in decreased expression of TFDP2 mRNA CTD PMID:21632981 SB 431542 multiple interactions ISO RGD:1314075 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silver(1+) nitrate increases expression ISO RGD:1314075 6480464 Silver Nitrate analog results in increased expression of TFDP2 mRNA CTD PMID:22831968 Soman increases expression ISO RGD:1305814 6480464 Soman results in increased expression of TFDP2 mRNA CTD PMID:19281266 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TFDP2 mRNA CTD PMID:21641980 tamibarotene decreases expression ISO RGD:1314075 6480464 tamibarotene results in decreased expression of TFDP2 mRNA CTD PMID:15498508 tamoxifen increases expression ISO RGD:1314075 6480464 Tamoxifen results in increased expression of TFDP2 mRNA CTD PMID:15590111 testosterone undecanoate decreases expression ISO RGD:1314075 6480464 testosterone undecanoate results in decreased expression of TFDP2 mRNA CTD PMID:19074003 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of TFDP2 mRNA CTD PMID:17484886 tetrachloromethane decreases expression ISO RGD:1305814 6480464 Carbon Tetrachloride results in decreased expression of TFDP2 mRNA CTD PMID:31150632 topotecan multiple interactions ISO RGD:1305814 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of TFDP2 mRNA CTD PMID:25729387 topotecan decreases expression ISO RGD:1305814 6480464 Topotecan results in decreased expression of TFDP2 mRNA CTD PMID:25729387 trichloroethene increases methylation ISO RGD:1305814 6480464 Trichloroethylene results in increased methylation of TFDP2 gene CTD PMID:27618143 trichostatin A decreases expression ISO RGD:1314075 6480464 trichostatin A results in decreased expression of TFDP2 mRNA CTD PMID:26272509 trichostatin A multiple interactions ISO RGD:1314075 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TFDP2 mRNA CTD PMID:27188386 Triptolide increases expression ISO RGD:1305814 6480464 triptolide results in increased expression of TFDP2 mRNA CTD PMID:23639586 urethane increases expression ISO RGD:1314075 6480464 Urethane results in increased expression of TFDP2 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:1314075 6480464 Valproic Acid results in decreased expression of TFDP2 mRNA CTD PMID:23179753 , PMID:28001369 valproic acid affects expression ISO RGD:1314075 6480464 Valproic Acid affects the expression of TFDP2 mRNA CTD PMID:25979313 
Gene-Chemical Interaction Annotations
