Tspan4 (tetraspanin 4) - Rat Genome Database

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Gene: Tspan4 (tetraspanin 4) Mus musculus
Analyze
Symbol: Tspan4
Name: tetraspanin 4
RGD ID: 1552299
MGI Page MGI
Description: Predicted to enable antigen binding activity and integrin binding activity. Acts upstream of or within mitocytosis and regulation of mitochondrial membrane potential. Located in migrasome. Is expressed in several structures, including gut; jaw; rib cage; urinary system; and viscerocranium. Orthologous to human TSPAN4 (tetraspanin 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI325509; AI746565; D130042I01Rik; MGC102386; NAG; NAG-2; novel antigen 2; tetraspan TM4SF; tetraspanin-4; Tm4sf; Tm4sf7; transmembrane 4 superfamily member 7; Tsp; Tspan-4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,055,194 - 141,073,340 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,055,153 - 141,073,340 (+)EnsemblGRCm39 Ensembl
GRCm387141,475,236 - 141,493,427 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,475,240 - 141,493,427 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,661,139 - 148,679,321 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,326,560 - 141,344,742 (+)NCBIMGSCv36mm8
Celera7141,269,031 - 141,287,223 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
C60 fullerene  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
chrysene  (EXP)
clofibrate  (EXP)
cobalt dichloride  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
dioxygen  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
fipronil  (ISO)
fulvestrant  (ISO)
glafenine  (ISO)
inulin  (EXP)
irinotecan  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (EXP,ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenformin  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sulfadimethoxine  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
migrasome  (IDA)
plasma membrane  (IBA,ISO)
vesicle  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Sequences and expression of six new members of the tetraspanin/TM4SF family. Todd SC, etal., Biochim Biophys Acta 1998 Jul 30;1399(1):101-4.
Additional References at PubMed
PMID:8889548   PMID:9360996   PMID:9874197   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11591653   PMID:12477932   PMID:12583998   PMID:12904583   PMID:14610273   PMID:15489334  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:18291621   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23375831   PMID:34048705   PMID:36513632  


Genomics

Comparative Map Data
Tspan4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,055,194 - 141,073,340 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,055,153 - 141,073,340 (+)EnsemblGRCm39 Ensembl
GRCm387141,475,236 - 141,493,427 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,475,240 - 141,493,427 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,661,139 - 148,679,321 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,326,560 - 141,344,742 (+)NCBIMGSCv36mm8
Celera7141,269,031 - 141,287,223 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.83NCBI
TSPAN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811842,852 - 867,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11842,812 - 867,116 (+)EnsemblGRCh38hg38GRCh38
GRCh3711842,852 - 867,111 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611832,824 - 857,116 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411832,823 - 857,109NCBI
Celera11880,283 - 934,195 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11658,171 - 682,321 (+)NCBIHuRef
CHM1_111841,866 - 866,158 (+)NCBICHM1_1
T2T-CHM13v2.011894,229 - 918,529 (+)NCBIT2T-CHM13v2.0
Tspan4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81206,001,731 - 206,021,414 (+)NCBIGRCr8
mRatBN7.21196,571,307 - 196,593,842 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,572,228 - 196,617,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,917,529 - 204,936,996 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,046,034 - 212,065,754 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,720,184 - 204,739,903 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,454,090 - 214,473,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,454,090 - 214,473,741 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,016,897 - 214,038,723 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,934,413 - 220,954,110 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,661,391 - 201,681,042 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1194,205,671 - 194,225,302 (+)NCBICelera
Cytogenetic Map1q41NCBI
Tspan4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,277,881 - 11,289,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,277,881 - 11,291,008 (-)NCBIChiLan1.0ChiLan1.0
TSPAN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,241,748 - 3,266,110 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,451,737 - 2,476,104 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011861,598 - 885,957 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111904,683 - 928,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11905,157 - 928,480 (+)Ensemblpanpan1.1panPan2
TSPAN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11845,220,763 - 45,224,981 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1845,203,620 - 45,224,674 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1843,869,557 - 43,891,669 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01845,867,525 - 45,889,748 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,875,251 - 45,889,721 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,332,357 - 45,354,370 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,897,103 - 44,919,232 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,635,240 - 45,657,457 (+)NCBIUU_Cfam_GSD_1.0
Tspan4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947602,005 - 618,275 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888601,887 - 622,244 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888601,834 - 618,092 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2534,341 - 550,697 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12532,087 - 550,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22123,615 - 142,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11649,316 - 673,317 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1650,407 - 673,763 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,738,857 - 97,762,755 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspan4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,666,302 - 21,673,693 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,666,330 - 21,678,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tspan4
542 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1085
Count of miRNA genes:444
Interacting mature miRNAs:526
Transcripts:ENSMUST00000026585, ENSMUST00000117634, ENSMUST00000130402, ENSMUST00000138092, ENSMUST00000140858, ENSMUST00000146305
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse

Markers in Region
RH126879  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,493,191 - 141,493,419UniSTSGRCm38
MGSCv377148,679,090 - 148,679,318UniSTSGRCm37
Celera7141,286,992 - 141,287,220UniSTS
Cytogenetic Map7F5UniSTS
Whitehead/MRC_RH71427.51UniSTS
AI746565  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,492,947 - 141,493,049UniSTSGRCm38
MGSCv377148,678,846 - 148,678,948UniSTSGRCm37
Celera7141,286,748 - 141,286,850UniSTS
Cytogenetic Map7F5UniSTS
Whitehead/MRC_RH71428.85UniSTS
35.MMHAP17FRD11.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,476,085 - 141,476,235UniSTSGRCm38
MGSCv377148,661,984 - 148,662,134UniSTSGRCm37
Celera7141,269,876 - 141,270,026UniSTS
Cytogenetic Map7F5UniSTS
Whitehead_YAC2 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC158224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY159328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB954815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD741422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026585   ⟹   ENSMUSP00000026585
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,055,153 - 141,073,340 (+)Ensembl
GRCm38.p6 Ensembl7141,475,240 - 141,493,427 (+)Ensembl
RefSeq Acc Id: ENSMUST00000117634   ⟹   ENSMUSP00000113085
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,056,313 - 141,073,334 (+)Ensembl
GRCm38.p6 Ensembl7141,476,400 - 141,493,421 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130402
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,071,402 - 141,072,873 (+)Ensembl
GRCm38.p6 Ensembl7141,491,489 - 141,492,960 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138092   ⟹   ENSMUSP00000115421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,055,423 - 141,071,716 (+)Ensembl
GRCm38.p6 Ensembl7141,475,510 - 141,491,803 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140858   ⟹   ENSMUSP00000118936
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,055,649 - 141,069,533 (+)Ensembl
GRCm38.p6 Ensembl7141,475,736 - 141,489,620 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146305   ⟹   ENSMUSP00000118533
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,055,426 - 141,071,729 (+)Ensembl
GRCm38.p6 Ensembl7141,475,513 - 141,491,816 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239217   ⟹   ENSMUSP00000159235
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,061,977 - 141,072,866 (+)Ensembl
GRCm38.p6 Ensembl7141,482,064 - 141,492,953 (+)Ensembl
RefSeq Acc Id: NM_001252588   ⟹   NP_001239517
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,056,337 - 141,073,340 (+)NCBI
GRCm387141,476,380 - 141,493,427 (+)NCBI
Celera7141,269,027 - 141,287,228 (+)ENTREZGENE
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001403355   ⟹   NP_001390284
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,055,194 - 141,073,340 (+)NCBI
RefSeq Acc Id: NM_001403356   ⟹   NP_001390285
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,055,194 - 141,073,340 (+)NCBI
RefSeq Acc Id: NM_001403357   ⟹   NP_001390286
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,055,194 - 141,073,340 (+)NCBI
RefSeq Acc Id: NM_001403358   ⟹   NP_001390287
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,061,994 - 141,073,340 (+)NCBI
RefSeq Acc Id: NM_053082   ⟹   NP_444312
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,055,194 - 141,073,340 (+)NCBI
GRCm387141,475,236 - 141,493,427 (+)ENTREZGENE
MGSCv377148,661,139 - 148,679,321 (+)RGD
Celera7141,269,027 - 141,287,228 (+)ENTREZGENE
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036153326   ⟹   XP_036009219
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,055,392 - 141,073,340 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036153327   ⟹   XP_036009220
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,056,280 - 141,073,340 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_444312   ⟸   NM_053082
- Peptide Label: isoform a
- UniProtKB: Q9DCK3 (UniProtKB/Swiss-Prot),   Q4FJW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001239517   ⟸   NM_001252588
- Peptide Label: isoform a
- UniProtKB: Q9DCK3 (UniProtKB/Swiss-Prot),   Q4FJW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000026585   ⟸   ENSMUST00000026585
RefSeq Acc Id: ENSMUSP00000115421   ⟸   ENSMUST00000138092
RefSeq Acc Id: ENSMUSP00000159235   ⟸   ENSMUST00000239217
RefSeq Acc Id: ENSMUSP00000118533   ⟸   ENSMUST00000146305
RefSeq Acc Id: ENSMUSP00000118936   ⟸   ENSMUST00000140858
RefSeq Acc Id: ENSMUSP00000113085   ⟸   ENSMUST00000117634
RefSeq Acc Id: XP_036009219   ⟸   XM_036153326
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036009220   ⟸   XM_036153327
- Peptide Label: isoform X3
RefSeq Acc Id: NP_001390284   ⟸   NM_001403355
- Peptide Label: isoform a
- UniProtKB: Q9DCK3 (UniProtKB/Swiss-Prot),   Q4FJW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390286   ⟸   NM_001403357
- Peptide Label: isoform a
- UniProtKB: Q9DCK3 (UniProtKB/Swiss-Prot),   Q4FJW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390285   ⟸   NM_001403356
- Peptide Label: isoform a
- UniProtKB: Q9DCK3 (UniProtKB/Swiss-Prot),   Q4FJW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390287   ⟸   NM_001403358
- Peptide Label: isoform b
- UniProtKB: A0A668KLD1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DCK3-F1-model_v2 AlphaFold Q9DCK3 1-238 view protein structure

Promoters
RGD ID:8666147
Promoter ID:EPDNEW_M11104
Type:initiation region
Name:Tspan4_1
Description:Mus musculus tetraspanin 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11105  EPDNEW_M11106  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387141,475,283 - 141,475,343EPDNEW
RGD ID:8666149
Promoter ID:EPDNEW_M11105
Type:multiple initiation site
Name:Tspan4_3
Description:Mus musculus tetraspanin 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11104  EPDNEW_M11106  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387141,475,579 - 141,475,639EPDNEW
RGD ID:8666151
Promoter ID:EPDNEW_M11106
Type:initiation region
Name:Tspan4_2
Description:Mus musculus tetraspanin 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11104  EPDNEW_M11105  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387141,476,424 - 141,476,484EPDNEW
RGD ID:6841799
Promoter ID:MM_KWN:53276
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_025593,   OTTMUST00000071730,   OTTMUST00000071732,   OTTMUST00000071733,   OTTMUST00000071734,   UC009KLO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367148,660,131 - 148,662,867 (-)MPROMDB
RGD ID:6842263
Promoter ID:MM_KWN:53277
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000071735
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367148,676,631 - 148,677,722 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928097 AgrOrtholog
Ensembl Genes ENSMUSG00000025511 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026585 ENTREZGENE
  ENSMUST00000026585.14 UniProtKB/Swiss-Prot
  ENSMUST00000117634 ENTREZGENE
  ENSMUST00000117634.2 UniProtKB/Swiss-Prot
  ENSMUST00000138092.8 UniProtKB/TrEMBL
  ENSMUST00000140858.8 UniProtKB/TrEMBL
  ENSMUST00000146305.8 UniProtKB/TrEMBL
  ENSMUST00000239217 ENTREZGENE
  ENSMUST00000239217.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin/Peripherin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:64540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1928097 ENTREZGENE
NCBI Gene 64540 ENTREZGENE
PANTHER PTHR19282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TETRASPANIN-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tspan4 PhenoGen
PIRSF Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TM4_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48652 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A668KLD1 ENTREZGENE, UniProtKB/TrEMBL
  D3YXS4_MOUSE UniProtKB/TrEMBL
  D3Z0B7_MOUSE UniProtKB/TrEMBL
  D3Z0T3_MOUSE UniProtKB/TrEMBL
  Q4FJW7 ENTREZGENE, UniProtKB/TrEMBL
  Q9DCK3 ENTREZGENE, UniProtKB/Swiss-Prot