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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | decreases expression | ISO | RGD:1343910 | 6480464 | epigallocatechin gallate results in decreased expression of HAS1 mRNA | CTD | PMID:20706672 | 1,4-phenylenediamine | increases expression | ISO | RGD:1343910 | 6480464 | 4-phenylenediamine results in increased expression of HAS1 mRNA, 4-phenylenediamine results in increased expression of HAS1 protein | CTD | PMID:31226360 | 1-chloro-2,4-dinitrobenzene | increases expression | ISO | RGD:1343910 | 6480464 | Dinitrochlorobenzene results in increased expression of HAS1 mRNA, Dinitrochlorobenzene results in increased expression of HAS1 protein | CTD | PMID:31226360 | 17beta-estradiol | multiple interactions | ISO | RGD:1343910 | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of HAS1 mRNA | CTD | PMID:20226447 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of HAS1 mRNA | CTD | PMID:19484750 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:708528 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of HAS1 mRNA | CTD | PMID:33387578 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1343910 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HAS1 mRNA more ... | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1343910 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HAS1 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of HAS1 mRNA | CTD | PMID:28973697 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of HAS1 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | increases expression | EXP | | 6480464 | Decitabine results in increased expression of HAS1 mRNA | CTD | PMID:27915011 | acrylamide | decreases expression | ISO | RGD:708528 | 6480464 | Acrylamide results in decreased expression of HAS1 mRNA | CTD | PMID:28959563 | ammonium chloride | affects expression | ISO | RGD:708528 | 6480464 | Ammonium Chloride affects the expression of HAS1 mRNA | CTD | PMID:16483693 | amphetamine | increases expression | ISO | RGD:708528 | 6480464 | Amphetamine results in increased expression of HAS1 mRNA | CTD | PMID:30779732 | antirheumatic drug | decreases expression | ISO | RGD:1343910 | 6480464 | Antirheumatic Agents results in decreased expression of HAS1 mRNA | CTD | PMID:24449571 | aristolochic acid | increases expression | ISO | RGD:1343910 | 6480464 | aristolochic acid I results in increased expression of HAS1 mRNA | CTD | PMID:33212167 | arsenite(3-) | decreases expression | EXP | | 6480464 | arsenite results in decreased expression of HAS1 mRNA | CTD | PMID:18929588 | benzene | increases expression | ISO | RGD:1343910 | 6480464 | Benzene results in increased expression of HAS1 mRNA | CTD | PMID:19162166 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of HAS1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | RGD:1343910 | 6480464 | Benzo(a)pyrene affects the methylation of HAS1 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:1343910 | 6480464 | Diethylhexyl Phthalate results in decreased expression of HAS1 mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | ISO | RGD:708528 | 6480464 | bisphenol A affects the expression of HAS1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:708528 | 6480464 | bisphenol A results in decreased expression of HAS1 mRNA | CTD | PMID:34947998 | bisphenol A | multiple interactions | ISO | RGD:1343910 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HAS1 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | ISO | RGD:1343910 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of HAS1 mRNA | CTD | PMID:28628672 | cadmium dichloride | decreases expression | ISO | RGD:708528 | 6480464 | Cadmium Chloride results in decreased expression of HAS1 mRNA | CTD | PMID:33453195 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorogenic acid | increases expression | ISO | RGD:1343910 | 6480464 | Chlorogenic Acid results in increased expression of HAS1 mRNA | CTD | PMID:20706672 | crocidolite asbestos | affects expression | ISO | RGD:1343910 | 6480464 | Asbestos, Crocidolite affects the expression of HAS1 mRNA | CTD | PMID:25757056 | dexamethasone | multiple interactions | ISO | RGD:1343910 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HAS1 mRNA more ... | CTD | PMID:28628672 | dioxygen | decreases expression | EXP | | 6480464 | Oxygen deficiency results in decreased expression of HAS1 mRNA | CTD | PMID:24205000 | dioxygen | multiple interactions | ISO | RGD:708528 | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of HAS1 mRNA | CTD | PMID:33729688 | furan | increases expression | ISO | RGD:708528 | 6480464 | furan results in increased expression of HAS1 mRNA | CTD | PMID:27387713 | genistein | decreases expression | ISO | RGD:1343910 | 6480464 | Genistein results in decreased expression of HAS1 mRNA | CTD | PMID:20706672 | gentamycin | increases expression | ISO | RGD:708528 | 6480464 | Gentamicins results in increased expression of HAS1 mRNA | CTD | PMID:33387578 | graphite | affects expression | ISO | RGD:708528 | 6480464 | Graphite affects the expression of HAS1 mRNA | CTD | PMID:29933104 | hyaluronic acid | increases expression | ISO | RGD:1343910 | 6480464 | Hyaluronic Acid metabolite results in increased expression of HAS1 mRNA, Hyaluronic Acid metabolite results in increased expression of HAS1 protein | CTD | PMID:31226360 | Indeno[1,2,3-cd]pyrene | decreases expression | EXP | | 6480464 | indeno(1 more ... | CTD | PMID:26377693 | indometacin | multiple interactions | ISO | RGD:1343910 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HAS1 mRNA more ... | CTD | PMID:28628672 | lead(0) | affects expression | ISO | RGD:1343910 | 6480464 | Lead affects the expression of HAS1 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:1343910 | 6480464 | Lead affects the expression of HAS1 mRNA | CTD | PMID:28903495 | Licochalcone B | increases expression | ISO | RGD:1343910 | 6480464 | licochalcone B results in increased expression of HAS1 mRNA | CTD | PMID:33647349 | methylparaben | decreases expression | ISO | RGD:1343910 | 6480464 | methylparaben results in decreased expression of HAS1 mRNA | CTD | PMID:17186576 | Osajin | decreases expression | ISO | RGD:1343910 | 6480464 | osajin results in decreased expression of HAS1 mRNA | CTD | PMID:20706672 | ozone | decreases expression | EXP | | 6480464 | Ozone results in decreased expression of HAS1 mRNA | CTD | PMID:31626304 | paracetamol | affects expression | ISO | RGD:708528 | 6480464 | Acetaminophen affects the expression of HAS1 mRNA | CTD | PMID:33387578 | paraquat | increases expression | ISO | RGD:708528 | 6480464 | Paraquat results in increased expression of HAS1 mRNA | CTD | PMID:32680482 | progesterone | multiple interactions | ISO | RGD:1343910 | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of HAS1 mRNA | CTD | PMID:20226447 | puerarin | decreases expression | ISO | RGD:1343910 | 6480464 | puerarin results in decreased expression of HAS1 mRNA | CTD | PMID:20706672 | resveratrol | decreases expression | ISO | RGD:1343910 | 6480464 | resveratrol results in decreased expression of HAS1 mRNA | CTD | PMID:20706672 | Rosavin | decreases expression | ISO | RGD:1343910 | 6480464 | rosavin results in decreased expression of HAS1 mRNA | CTD | PMID:20706672 | sodium arsenite | affects methylation | ISO | RGD:1343910 | 6480464 | sodium arsenite affects the methylation of HAS1 gene | CTD | PMID:28589171 | Tesaglitazar | increases expression | ISO | RGD:708528 | 6480464 | tesaglitazar results in increased expression of HAS1 mRNA | CTD | PMID:21515302 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of HAS1 mRNA | CTD | PMID:27042213 | tetrachloromethane | multiple interactions | EXP | | 6480464 | HAS3 protein affects the reaction [Carbon Tetrachloride results in increased expression of HAS1 mRNA] | CTD | PMID:27042213 | thioacetamide | increases expression | ISO | RGD:708528 | 6480464 | Thioacetamide results in increased expression of HAS1 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | ISO | RGD:708528 | 6480464 | Trichloroethylene results in increased expression of HAS1 mRNA | CTD | PMID:33387578 | triclosan | increases expression | ISO | RGD:1343910 | 6480464 | Triclosan results in increased expression of HAS1 mRNA | CTD | PMID:30510588 | |