Slc10a6 (solute carrier family 10 (sodium/bile acid cotransporter family), member 6) - Rat Genome Database
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Gene: Slc10a6 (solute carrier family 10 (sodium/bile acid cotransporter family), member 6) Mus musculus
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Symbol: Slc10a6
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 6
RGD ID: 1552165
MGI Page MGI
Description: Predicted to have bile acid:sodium symporter activity and sodium-dependent organic anion transmembrane transporter activity. Predicted to be involved in bile acid and bile salt transport and sodium-dependent organic anion transport. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in metanephros. Orthologous to human SLC10A6 (solute carrier family 10 member 6); INTERACTS WITH 1,2-dimethylhydrazine; 4-hydroxyphenyl retinamide; arsane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 8430417G17Rik; C78479; MGC149979; Soat; sodium-dependent organic anion transporter; solute carrier family 10 member 6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395103,753,577 - 103,777,269 (-)NCBIGRCm39mm39
GRCm385103,605,711 - 103,629,403 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5103,605,711 - 103,629,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv375104,034,730 - 104,058,422 (-)NCBIGRCm37mm9NCBIm37
MGSCv365103,846,013 - 103,869,705 (-)NCBImm8
Celera5100,917,865 - 100,940,762 (-)NCBICelera
Cytogenetic Map5E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16919269   PMID:19521566   PMID:21267068   PMID:21873635   PMID:23375831   PMID:23562556  
PMID:28743544  


Genomics

Comparative Map Data
Slc10a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395103,753,577 - 103,777,269 (-)NCBIGRCm39mm39
GRCm385103,605,711 - 103,629,403 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5103,605,711 - 103,629,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv375104,034,730 - 104,058,422 (-)NCBIGRCm37mm9NCBIm37
MGSCv365103,846,013 - 103,869,705 (-)NCBImm8
Celera5100,917,865 - 100,940,762 (-)NCBICelera
Cytogenetic Map5E5NCBI
SLC10A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl486,823,468 - 86,849,384 (-)EnsemblGRCh38hg38GRCh38
GRCh38486,823,468 - 86,849,384 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37487,744,477 - 87,770,416 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37487,744,621 - 87,770,537 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36487,963,865 - 87,989,292 (-)NCBINCBI36hg18NCBI36
Celera485,034,180 - 85,059,864 (-)NCBI
Cytogenetic Map4q21.3NCBI
HuRef483,489,562 - 83,515,298 (-)NCBIHuRef
CHM1_1487,721,091 - 87,746,835 (-)NCBICHM1_1
Slc10a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2146,080,716 - 6,102,037 (+)NCBI
Rnor_6.0 Ensembl147,618,022 - 7,682,377 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0147,618,022 - 7,682,377 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0147,592,605 - 7,656,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,270,695 - 7,292,036 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1147,270,694 - 7,292,036 (+)NCBI
Celera146,219,788 - 6,240,844 (+)NCBICelera
Cytogenetic Map14p22NCBI
Slc10a6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554742,951,052 - 2,980,980 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554742,949,773 - 2,982,458 (+)NCBIChiLan1.0ChiLan1.0
SLC10A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1489,855,914 - 89,881,523 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl489,855,914 - 89,881,523 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0479,126,941 - 79,152,786 (-)NCBIMhudiblu_PPA_v0panPan3
SLC10A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3210,279,831 - 10,386,298 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13210,334,148 - 10,362,302 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc10a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936920285,185 - 310,395 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC10A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8131,969,291 - 132,021,981 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18131,997,359 - 132,023,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28141,308,101 - 141,336,069 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC10A6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1735,203,853 - 35,230,698 (-)NCBI
ChlSab1.1 Ensembl735,203,853 - 35,229,199 (-)Ensembl
Slc10a6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248723,411,860 - 3,438,525 (-)NCBI

Position Markers
C78479  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385103,605,746 - 103,605,844UniSTSGRCm38
MGSCv375104,034,765 - 104,034,863UniSTSGRCm37
Celera5100,917,900 - 100,917,998UniSTS
Cytogenetic Map5E5UniSTS
Whitehead/MRC_RH51222.45UniSTS
UniSTS:235238  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385103,605,752 - 103,606,008UniSTSGRCm38
MGSCv375104,034,771 - 104,035,027UniSTSGRCm37
Celera5100,917,906 - 100,918,162UniSTS
Cytogenetic Map5E5UniSTS
Slc10a6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5E5UniSTS
cM Map550.45UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537424144112317856Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552537120107173175Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552537120107173175Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55230992108614761Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563548099104239199Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572271017106271152Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574300000132500000Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574300000132500000Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575154687119880564Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576042404110042620Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576132927110133058Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576132927110133058Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576132927110133058Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576297205110297366Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576297205110297366Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576297205110297366Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576297205110297366Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579391781113391927Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580701400114701400Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined580871790114871944Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582690609116690738Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582690609116690738Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587239005121239199Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587239005121239199Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587239005121239199Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587239005121239199Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587239005121239199Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589271017118725963Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589271017124100176Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590173096124173175Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590413140124413285Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590413140124413285Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592682300126682419Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595085348129085464Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595286714129286920Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595317683129317856Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595317683129317856Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595317683129317856Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596172519130172667Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined596883692130883925Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined596883692130883925Mouse
10045978Tir10_mtrypanosome infection response 10 (mouse)Not determined597871790113883925Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined597871790116738565Mouse
1301877Bbaa3_mB.burgdorferi-associated arthritis 3 (mouse)Not determined599307426112317856Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99801563126805880Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100527900134527900Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100527900134527900Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101194514135194514Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101725767135725963Mouse
14746986Manh58_mmandible shape 58 (mouse)5102308218136308218Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102806972136807131Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5102900000115400000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:200
Interacting mature miRNAs:207
Transcripts:ENSMUST00000031263
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000031263   ⟹   ENSMUSP00000031263
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5103,605,711 - 103,629,403 (-)Ensembl
RefSeq Acc Id: NM_029415   ⟹   NP_083691
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395103,753,577 - 103,777,269 (-)NCBI
GRCm385103,605,711 - 103,629,403 (-)NCBI
MGSCv375104,034,730 - 104,058,422 (-)RGD
Celera5100,917,865 - 100,940,762 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006535278   ⟹   XP_006535341
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395103,753,654 - 103,777,043 (-)NCBI
GRCm385103,605,788 - 103,629,168 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083691   ⟸   NM_029415
- UniProtKB: Q9CXB2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006535341   ⟸   XM_006535278
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000031263   ⟸   ENSMUST00000031263

Promoters
RGD ID:6887322
Promoter ID:EPDNEW_M7112
Type:multiple initiation site
Name:Slc10a6_1
Description:Mus musculus solute carrier family 10 (sodium/bile acid cotransporterfamily), member 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385103,629,286 - 103,629,346EPDNEW
RGD ID:6838353
Promoter ID:MM_KWN:43130
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   Kidney,   Lung
Transcripts:NM_029415
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365104,058,134 - 104,058,634 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923000 AgrOrtholog
Ensembl Genes ENSMUSG00000029321 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000031263 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031263 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1530.20 UniProtKB/Swiss-Prot
InterPro BilAc:Na_symport/Acr3 UniProtKB/Swiss-Prot
  Bilac:Na_transpt UniProtKB/Swiss-Prot
  Na+/solute_symporter_sf UniProtKB/Swiss-Prot
  SLC10A6 UniProtKB/Swiss-Prot
KEGG Report mmu:75750 UniProtKB/Swiss-Prot
MGD MGI:1923000 ENTREZGENE
NCBI Gene 75750 ENTREZGENE
PANTHER PTHR10361 UniProtKB/Swiss-Prot
  PTHR10361:SF55 UniProtKB/Swiss-Prot
Pfam SBF UniProtKB/Swiss-Prot
PhenoGen Slc10a6 PhenoGen
UniProt Q9CXB2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RTH4 UniProtKB/Swiss-Prot