Gmcl1 (germ cell-less, spermatogenesis associated 1) - Rat Genome Database
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Gene: Gmcl1 (germ cell-less, spermatogenesis associated 1) Mus musculus
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Symbol: Gmcl1
Name: germ cell-less, spermatogenesis associated 1
RGD ID: 1552095
MGI Page MGI
Description: Is expressed in several structures, including eye; genitourinary system; hemolymphoid system gland; liver; and lung. Orthologous to several human genes including GMCL1 (germ cell-less 1, spermatogenesis associated); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810049L19Rik; Btbd13; DIP; DP-interacting protein; Gc; Gcl; Gcl-1; germ cell-less homolog 1; germ cell-less protein-like 1; glc-1; mGcl-1; mglc-; mglc-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Btbd35f24   Gm371  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,668,750 - 86,710,377 (-)NCBIGRCm39mm39
GRCm39 Ensembl686,668,750 - 86,710,365 (-)Ensembl
GRCm38686,691,768 - 86,733,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,691,768 - 86,733,383 (-)EnsemblGRCm38mm10GRCm38
MGSCv37686,641,762 - 86,683,372 (-)NCBIGRCm37mm9NCBIm37
MGSCv36686,657,404 - 86,698,988 (-)NCBImm8
Celera688,630,051 - 88,672,978 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:9878064   PMID:10349636   PMID:10727854   PMID:11042159   PMID:11076861   PMID:11591818   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15700541   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:17010969   PMID:20059953   PMID:21873635  


Genomics

Comparative Map Data
Gmcl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,668,750 - 86,710,377 (-)NCBIGRCm39mm39
GRCm39 Ensembl686,668,750 - 86,710,365 (-)Ensembl
GRCm38686,691,768 - 86,733,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,691,768 - 86,733,383 (-)EnsemblGRCm38mm10GRCm38
MGSCv37686,641,762 - 86,683,372 (-)NCBIGRCm37mm9NCBIm37
MGSCv36686,657,404 - 86,698,988 (-)NCBImm8
Celera688,630,051 - 88,672,978 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.75NCBI
GMCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl269,829,660 - 69,881,384 (+)EnsemblGRCh38hg38GRCh38
GRCh38269,829,660 - 69,881,389 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37270,056,792 - 70,108,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,910,322 - 69,960,231 (+)NCBINCBI36hg18NCBI36
Celera269,907,998 - 69,957,903 (+)NCBI
Cytogenetic Map2p13.3NCBI
HuRef269,792,818 - 69,842,714 (+)NCBIHuRef
CHM1_1269,986,367 - 70,038,178 (+)NCBICHM1_1
Gmcl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24119,140,598 - 119,179,891 (-)NCBI
Rnor_6.0 Ensembl4118,478,075 - 118,534,280 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04118,494,997 - 118,534,301 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04183,065,011 - 183,104,417 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,845,606 - 120,885,122 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14121,095,689 - 121,129,398 (-)NCBI
Celera4108,110,660 - 108,149,940 (-)NCBICelera
Cytogenetic Map4q34NCBI
Gmcl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542415,265,052 - 15,318,445 (-)NCBIChiLan1.0ChiLan1.0
GMCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A70,990,081 - 71,041,510 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A70,990,117 - 71,040,526 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A69,872,537 - 69,924,175 (+)NCBIMhudiblu_PPA_v0panPan3
GMCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,469,369 - 68,525,961 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gmcl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649114,051,538 - 14,097,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1372,570,426 - 72,619,696 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2375,965,018 - 76,057,340 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GMCL1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11437,242,401 - 37,294,917 (-)NCBI
ChlSab1.1 Ensembl1437,241,305 - 37,294,655 (-)Ensembl
Gmcl1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247623,522,534 - 3,558,750 (-)NCBI

Position Markers
BB540852  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38686,722,290 - 86,722,410UniSTSGRCm38
MGSCv37686,672,284 - 86,672,404UniSTSGRCm37
Celera688,661,899 - 88,662,019UniSTS
Cytogenetic Map6D1UniSTS
cM Map647.3UniSTS
Whitehead/MRC_RH6893.07UniSTS
RH128814  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38686,691,874 - 86,692,057UniSTSGRCm38
MGSCv37686,641,868 - 86,642,051UniSTSGRCm37
Celera688,630,157 - 88,630,340UniSTS
Cytogenetic Map6D1UniSTS
cM Map647.3UniSTS
UniSTS:235484  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38686,714,197 - 86,714,414UniSTSGRCm38
MGSCv37686,664,191 - 86,664,408UniSTSGRCm37
Celera688,652,550 - 88,652,767UniSTS
Cytogenetic Map6D1UniSTS
cM Map647.3UniSTS
Gcl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38686,692,413 - 86,692,876UniSTSGRCm38
MGSCv37686,642,407 - 86,642,870UniSTSGRCm37
Celera688,630,696 - 88,631,159UniSTS
Cytogenetic Map6D1UniSTS
cM Map647.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:472
Count of miRNA genes:333
Interacting mature miRNAs:387
Transcripts:ENSMUST00000001185, ENSMUST00000113679, ENSMUST00000135880
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003956194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_377446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC158662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF163665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF163666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF186095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ122611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX567687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000001185   ⟹   ENSMUSP00000001185
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,691,768 - 86,733,383 (-)Ensembl
RefSeq Acc Id: ENSMUST00000113679   ⟹   ENSMUSP00000109309
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,720,210 - 86,733,240 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135880
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,714,228 - 86,718,606 (-)Ensembl
RefSeq Acc Id: ENSMUST00000203741
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,714,144 - 86,716,893 (-)Ensembl
RefSeq Acc Id: NM_011818   ⟹   NP_035948
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,668,750 - 86,710,360 (-)NCBI
GRCm38686,691,768 - 86,733,378 (-)NCBI
MGSCv37686,641,762 - 86,683,372 (-)RGD
Celera688,630,051 - 88,672,978 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506056   ⟹   XP_006506119
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,668,750 - 86,710,373 (-)NCBI
GRCm38686,691,768 - 86,733,387 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003956194
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,674,431 - 86,710,377 (-)NCBI
GRCm38686,697,449 - 86,733,395 (-)NCBI
Sequence:
RefSeq Acc Id: XR_377446
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,668,750 - 86,710,377 (-)NCBI
GRCm38686,691,768 - 86,733,395 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035948   ⟸   NM_011818
- UniProtKB: Q920G9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506119   ⟸   XM_006506056
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000109309   ⟸   ENSMUST00000113679
RefSeq Acc Id: ENSMUSP00000001185   ⟸   ENSMUST00000001185
Protein Domains
BTB

Promoters
RGD ID:6839397
Promoter ID:MM_KWN:46749
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000113679,   NM_011818
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36686,683,181 - 86,683,681 (-)MPROMDB
RGD ID:6890302
Promoter ID:EPDNEW_M8602
Type:initiation region
Name:Gmcl1_1
Description:Mus musculus germ cell-less, spermatogenesis associated 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38686,733,306 - 86,733,366EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1345156 AgrOrtholog
Ensembl Genes ENSMUSG00000001157 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000001185 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000109309 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001185 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000113679 UniProtKB/TrEMBL
InterPro BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gcl-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:23885 UniProtKB/Swiss-Prot
MGD MGI:1345156 ENTREZGENE
NCBI Gene 23885 ENTREZGENE
PANTHER PTHR23231 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gmcl1 PhenoGen
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GMCL1_MOUSE UniProtKB/Swiss-Prot
  Q3U2J9_MOUSE UniProtKB/TrEMBL
  Q3UID6_MOUSE UniProtKB/TrEMBL
  Q3V0Z2_MOUSE UniProtKB/TrEMBL
  Q920G9 ENTREZGENE
UniProt Secondary Q9DBW5 UniProtKB/Swiss-Prot
  Q9QUP6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Gmcl1  germ cell-less, spermatogenesis associated 1    germ cell-less homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED