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Gene: Nppc (natriuretic peptide type C) Mus musculus
Symbol: Nppc
Name: natriuretic peptide type C
Description: Exhibits signaling receptor binding activity. Involved in several processes, including cGMP biosynthetic process; growth plate cartilage development; and negative regulation of oocyte maturation. Predicted to localize to the extracellular space; protein-containing complex; and secretory granule. Human ortholog(s) of this gene implicated in hypertension. Is expressed in central nervous system and vertebral cartilage condensation. Orthologous to human NPPC (natriuretic peptide C).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-type natriuretic peptide; CNP; lbab; MGC130574; natriuretic peptide precursor C; natriuretic peptide precursor type C
Homo sapiens (human) : NPPC (natriuretic peptide C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nppc (natriuretic peptide C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nppc (natriuretic peptide C)
Pan paniscus (bonobo/pygmy chimpanzee) : NPPC (natriuretic peptide C)
Canis lupus familiaris (dog) : NPPC (natriuretic peptide C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nppc (natriuretic peptide C)
Sus scrofa (pig) : NPPC (natriuretic peptide C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl186,666,291 - 86,670,571 (-)Ensembl
GRCm38186,666,293 - 86,670,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37188,562,866 - 88,567,147 (-)NCBIGRCm37mm9NCBIm37
MGSCv36188,497,462 - 88,501,743 (-)NCBImm8
Celera189,636,055 - 89,640,335 (-)NCBICelera
Cytogenetic Map1 C5NCBI
cM Map143.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nppc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551929
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.