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Gene: Efemp2 (epidermal growth factor-containing fibulin-like extracellular matrix protein 2) Mus musculus
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Symbol: Efemp2
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 2
Description: Predicted to have calcium ion binding activity and extracellular matrix constituent conferring elasticity. Involved in artery development and elastic fiber assembly. Localizes to the collagen-containing extracellular matrix and extracellular space. Used to study aortic aneurysm and cutis laxa. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IB. Is expressed in several structures, including central nervous system; genitourinary system; gut; immune system; and respiratory system. Orthologous to human EFEMP2 (EGF containing fibulin extracellular matrix protein 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610011K11Rik; EGF-containing fibulin-like extracellular matrix protein 2; EGF-containing fibulin-like extracellular matrix protein 2 (Efemp2); Fbln4; FIBL-4; fibulin 4; fibulin-4; MBP1; mutant p53-binding protein 1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38195,473,959 - 5,481,854 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,474,690 - 5,481,854 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,474,750 - 5,481,853 (+)NCBImm8
Celera195,346,431 - 5,353,554 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Efemp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551771
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.