Tspyl5 (testis-specific protein, Y-encoded-like 5) - Rat Genome Database

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Gene: Tspyl5 (testis-specific protein, Y-encoded-like 5) Mus musculus
Analyze
Symbol: Tspyl5
Name: testis-specific protein, Y-encoded-like 5
RGD ID: 1551760
MGI Page MGI
Description: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including cellular response to gamma radiation; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of protein ubiquitination. Predicted to be part of chromatin. Predicted to be active in nucleus. Orthologous to human TSPYL5 (TSPY like 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6330530B20; E130308C19Rik; testis-specific Y-encoded-like protein 5; TSPY-like protein 5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391533,684,021 - 33,688,029 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1533,684,021 - 33,688,030 (-)EnsemblGRCm39 Ensembl
GRCm381533,683,875 - 33,687,883 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1533,683,875 - 33,687,884 (-)EnsemblGRCm38mm10GRCm38
MGSCv371533,613,630 - 33,617,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361533,628,464 - 33,632,438 (-)NCBIMGSCv36mm8
Celera1534,331,686 - 34,335,694 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1513.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IBA)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15368895   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:37675714  


Genomics

Comparative Map Data
Tspyl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391533,684,021 - 33,688,029 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1533,684,021 - 33,688,030 (-)EnsemblGRCm39 Ensembl
GRCm381533,683,875 - 33,687,883 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1533,683,875 - 33,687,884 (-)EnsemblGRCm38mm10GRCm38
MGSCv371533,613,630 - 33,617,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361533,628,464 - 33,632,438 (-)NCBIMGSCv36mm8
Celera1534,331,686 - 34,335,694 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1513.91NCBI
TSPYL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38897,273,488 - 97,277,928 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl897,273,488 - 97,277,928 (-)EnsemblGRCh38hg38GRCh38
GRCh37898,285,716 - 98,290,156 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36898,354,890 - 98,359,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 34898,354,890 - 98,359,352NCBI
Celera894,471,979 - 94,476,441 (-)NCBICelera
Cytogenetic Map8q22.1NCBI
HuRef893,492,162 - 93,496,624 (-)NCBIHuRef
CHM1_1898,326,220 - 98,330,682 (-)NCBICHM1_1
T2T-CHM13v2.0898,399,254 - 98,403,693 (-)NCBIT2T-CHM13v2.0
Tspyl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8766,766,695 - 66,770,702 (-)NCBIGRCr8
mRatBN7.2764,881,504 - 64,885,512 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl764,884,225 - 64,885,457 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx766,770,762 - 66,774,769 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0768,972,458 - 68,976,465 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0768,760,803 - 68,764,819 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0772,323,764 - 72,328,228 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl772,326,896 - 72,328,128 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0772,494,474 - 72,498,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4769,061,484 - 69,063,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1769,082,672 - 69,096,515 (-)NCBI
Celera762,000,700 - 62,005,164 (-)NCBICelera
Cytogenetic Map7q22NCBI
Tspyl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541713,135,178 - 13,136,413 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541713,133,655 - 13,136,768 (-)NCBIChiLan1.0ChiLan1.0
TSPYL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27114,280,562 - 114,628,535 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1889,820,015 - 90,167,545 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0893,573,775 - 93,918,775 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1896,107,774 - 96,112,254 (-)NCBIpanpan1.1PanPan1.1panPan2
TSPYL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12941,500,395 - 41,503,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2941,503,312 - 41,503,956 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02941,694,456 - 41,698,042 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2941,697,356 - 41,698,537 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12941,733,965 - 41,737,553 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02941,703,848 - 41,707,446 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02942,168,839 - 42,172,437 (-)NCBIUU_Cfam_GSD_1.0
Tspyl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530337,959,029 - 37,984,221 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647045,385,239 - 45,386,486 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647045,385,155 - 45,410,307 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPYL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl439,362,947 - 39,367,402 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1439,362,945 - 39,367,405 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TSPYL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1892,217,919 - 92,222,373 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl892,221,034 - 92,222,287 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603948,542,674 - 48,866,217 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspyl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247634,568,123 - 4,569,664 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247634,564,966 - 4,569,495 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tspyl5
87 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1041
Count of miRNA genes:542
Interacting mature miRNAs:667
Transcripts:ENSMUST00000042021
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141358Ath22_matherosclerosis 22 (mouse)Not determined346465237464652Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562049439620614Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15612948138000244Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15682948144963396Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
27095922Pglq11_mpelvic girdle length QTL 11, 10 week (mouse)15812948438763395Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15812948447663396Mouse
10412172Habiir5_mhyperoxic acute lung injury imprinted region 5 (mouse)Not determined15927302243311880Mouse
4140994Shali3_msurvival time to hyperoxic acute lung injury 3 (mouse)Not determined927302243311880Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927302256186850Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1301020Pheo_mpheomelanin (mouse)Not determined151384700647847148Mouse
1302165Yv_myellow value (mouse)Not determined151384700647847148Mouse
4141423Nstr2_mnerve sheath tumor resistance QTL 2 (mouse)Not determined1492758748927756Mouse
1301951Eila3_methanol induced locomotor activity 3 (mouse)Not determined151492758748927756Mouse
1302007Bbaa14_mB.burgdorferi-associated arthritis 14 (mouse)Not determined151492758748927756Mouse
1301499Bdln2_mbody length 2 (mouse)Not determined151564534349645470Mouse
12859288Criq1_mCitrobacter rodentium infection QTL 1 (mouse)151603395450033954Mouse
26884423Zlq10_mzygomatic length QTL 10, 16 week (mouse)152060008650763396Mouse
14928313Manh78_mmandible shape 78 (mouse)152148464155484641Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152259376556593765Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2289301456893160Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152446257258462805Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152529580659295928Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2548497859484978Mouse
1301760Dob9_mdietary obesity 9 (mouse)Body fat amountadiposity index152603568037781301Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152631178060311880Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152631178060311880Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162631178060311880Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152631178060311880Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152828264662282739Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152828264662282739Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020014657963396Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse

Markers in Region
RH139565  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381533,683,934 - 33,684,119UniSTSGRCm38
MGSCv371533,613,689 - 33,613,874UniSTSGRCm37
Celera1534,331,745 - 34,331,930UniSTS
Cytogenetic Map15B3.1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000042021   ⟹   ENSMUSP00000045542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1533,684,021 - 33,688,030 (-)Ensembl
GRCm38.p6 Ensembl1533,683,875 - 33,687,884 (-)Ensembl
RefSeq Acc Id: NM_001085421   ⟹   NP_001078890
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391533,684,021 - 33,688,029 (-)NCBI
GRCm381533,683,875 - 33,687,883 (-)ENTREZGENE
MGSCv371533,613,630 - 33,617,638 (-)RGD
Celera1534,331,686 - 34,335,694 (-)RGD
cM Map15 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001078890 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD32531 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000045542
  ENSMUSP00000045542.4
GenBank Protein Q69ZB3 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001078890   ⟸   NM_001085421
- UniProtKB: Q69ZB3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000045542   ⟸   ENSMUST00000042021

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q69ZB3-F1-model_v2 AlphaFold Q69ZB3 1-406 view protein structure

Promoters
RGD ID:6826577
Promoter ID:MM_KWN:18212
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_001085421
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361533,617,256 - 33,617,756 (-)MPROMDB
RGD ID:8683550
Promoter ID:EPDNEW_M19805
Type:initiation region
Name:Tspyl5_1
Description:Mus musculus testis-specific protein, Y-encoded-like 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381533,687,851 - 33,687,911EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442458 AgrOrtholog
Ensembl Genes ENSMUSG00000038984 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000042021 ENTREZGENE
  ENSMUST00000042021.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.1500 UniProtKB/Swiss-Prot
  Nucleosome assembly protein UniProtKB/Swiss-Prot
InterPro NAP-like_sf UniProtKB/Swiss-Prot
  NAP_family UniProtKB/Swiss-Prot
KEGG Report mmu:239364 UniProtKB/Swiss-Prot
MGD MGI:2442458 ENTREZGENE
NCBI Gene 239364 ENTREZGENE
PANTHER PTHR11875 UniProtKB/Swiss-Prot
  TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 5 UniProtKB/Swiss-Prot
Pfam NAP UniProtKB/Swiss-Prot
PhenoGen Tspyl5 PhenoGen
Superfamily-SCOP SSF143113 UniProtKB/Swiss-Prot
UniProt Q69ZB3 ENTREZGENE, UniProtKB/Swiss-Prot