Ptpre (protein tyrosine phosphatase receptor type E) - Rat Genome Database

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Gene: Ptpre (protein tyrosine phosphatase receptor type E) Mus musculus
Analyze
Symbol: Ptpre
Name: protein tyrosine phosphatase receptor type E (Ensembl:protein tyrosine phosphatase, receptor type, E)
RGD ID: 1551707
MGI Page MGI
Description: Enables identical protein binding activity and protein tyrosine phosphatase activity. Involved in negative regulation of insulin receptor signaling pathway and regulation of mast cell activation. Acts upstream of or within transmembrane receptor protein tyrosine phosphatase signaling pathway. Located in cytoplasm and plasma membrane. Is expressed in midbrain and superior colliculus. Orthologous to human PTPRE (protein tyrosine phosphatase receptor type E).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: protein-tyrosine phosphatase epsilon; PT; PTPe; PTPepsilon; R-PTP-epsilon; receptor-type tyrosine-protein phosphatase epsilon; RP; RPTPepsilon
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397135,139,195 - 135,288,023 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7135,139,210 - 135,288,022 (+)EnsemblGRCm39 Ensembl
GRCm387135,537,824 - 135,686,294 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7135,537,481 - 135,686,293 (+)EnsemblGRCm38mm10GRCm38
MGSCv377142,729,507 - 142,877,977 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367135,376,167 - 135,524,637 (+)NCBIMGSCv36mm8
Celera7135,360,562 - 135,509,397 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map781.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP)
8-Br-cAMP  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
chromium(6+)  (EXP,ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (EXP)
fluoranthene  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
hydrazine  (EXP)
inulin  (EXP)
isobutanol  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
methapyrilene  (ISO)
methidathion  (EXP)
methylmercury chloride  (ISO)
mitoxantrone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,ISO)
membrane  (IEA)
nucleus  (ISO)
plasma membrane  (IDA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1454056   PMID:1932742   PMID:7592814   PMID:7832766   PMID:8267598   PMID:8575779   PMID:8610169   PMID:8618876   PMID:8838320   PMID:8875997   PMID:9406939   PMID:10349636  
PMID:10602512   PMID:10921884   PMID:10980613   PMID:11042159   PMID:11076861   PMID:12376545   PMID:12477932   PMID:12598528   PMID:12861030   PMID:14528021   PMID:14757526   PMID:14980517  
PMID:16141072   PMID:16141073   PMID:16512683   PMID:16715089   PMID:16870705   PMID:16919269   PMID:17709387   PMID:18006633   PMID:18093973   PMID:18308476   PMID:18776043   PMID:18924107  
PMID:19508371   PMID:19692574   PMID:19727691   PMID:19812040   PMID:19884258   PMID:21267068   PMID:21531338   PMID:21873635   PMID:22722941   PMID:22794259   PMID:24694598   PMID:25381250  
PMID:26812015   PMID:30615487   PMID:31844669   PMID:32325033  


Genomics

Comparative Map Data
Ptpre
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397135,139,195 - 135,288,023 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7135,139,210 - 135,288,022 (+)EnsemblGRCm39 Ensembl
GRCm387135,537,824 - 135,686,294 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7135,537,481 - 135,686,293 (+)EnsemblGRCm38mm10GRCm38
MGSCv377142,729,507 - 142,877,977 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367135,376,167 - 135,524,637 (+)NCBIMGSCv36mm8
Celera7135,360,562 - 135,509,397 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map781.27NCBI
PTPRE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810127,907,103 - 128,085,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl10127,907,103 - 128,085,855 (+)EnsemblGRCh38hg38GRCh38
GRCh3710129,705,367 - 129,884,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610129,595,315 - 129,774,155 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410129,735,823 - 129,774,155NCBI
Celera10123,376,798 - 123,555,655 (+)NCBICelera
Cytogenetic Map10q26.2NCBI
HuRef10123,280,118 - 123,458,889 (+)NCBIHuRef
CHM1_110129,987,736 - 130,166,586 (+)NCBICHM1_1
T2T-CHM13v2.010128,805,632 - 128,984,409 (+)NCBIT2T-CHM13v2.0
Ptpre
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21190,344,331 - 190,494,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1190,344,401 - 190,489,534 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1198,805,668 - 198,845,362 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01205,964,922 - 206,004,597 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01198,638,380 - 198,678,057 (+)NCBIRnor_WKY
Rnor_6.01207,820,719 - 207,987,123 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,887,209 - 207,987,136 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,818,446 - 214,920,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41195,263,489 - 195,303,249 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11195,421,407 - 195,453,236 (+)NCBI
Celera1188,164,525 - 188,204,261 (+)NCBICelera
Cytogenetic Map1q41NCBI
Ptpre
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554775,688,817 - 5,838,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554775,688,936 - 5,838,264 (+)NCBIChiLan1.0ChiLan1.0
PTPRE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan110139,790,073 - 139,969,429 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010124,494,150 - 124,673,579 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110128,744,234 - 128,922,584 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10128,836,367 - 128,922,584 (+)Ensemblpanpan1.1panPan2
PTPRE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12836,761,314 - 36,904,902 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2836,746,822 - 36,902,325 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2836,817,292 - 36,960,135 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02837,393,213 - 37,536,366 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2837,394,983 - 37,536,352 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12836,873,260 - 37,016,307 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02836,867,997 - 37,011,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02837,122,813 - 37,266,172 (+)NCBIUU_Cfam_GSD_1.0
Ptpre
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721310,001,450 - 10,130,358 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648615,484,300 - 15,559,849 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648615,484,304 - 15,559,842 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14137,101,555 - 137,264,238 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114137,101,449 - 137,264,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214149,003,851 - 149,166,646 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19120,511,812 - 120,691,820 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9120,646,898 - 120,690,230 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604881,900,758 - 82,082,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpre
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473718,977,042 - 19,020,284 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473718,977,142 - 19,129,112 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptpre
5090 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1032
Count of miRNA genes:559
Interacting mature miRNAs:690
Transcripts:ENSMUST00000073961
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1301903Tlsm1_mthymic lymphoma susceptible 1 (mouse)Not determined7122250663135170901Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse

Markers in Region
D7Mit13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387135,568,978 - 135,569,172UniSTSGRCm38
MGSCv377142,760,661 - 142,760,855UniSTSGRCm37
Celera7135,391,718 - 135,391,912UniSTS
Cytogenetic Map7F3UniSTS
cM Map766.0UniSTS
Whitehead Genetic762.3UniSTS
Whitehead_YAC7 UniSTS
Ptpre  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F3UniSTS
cM Map781.27UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001316678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001316679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001316680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001316681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001785494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC151838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC151841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY210317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D83484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U36758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U40280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U62387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z23053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000073961   ⟹   ENSMUSP00000073616
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,139,553 - 135,288,022 (+)Ensembl
GRCm38.p6 Ensembl7135,537,824 - 135,686,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000209256   ⟹   ENSMUSP00000147656
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,139,568 - 135,285,243 (+)Ensembl
GRCm38.p6 Ensembl7135,537,839 - 135,683,514 (+)Ensembl
RefSeq Acc Id: ENSMUST00000209268
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,139,553 - 135,142,924 (+)Ensembl
GRCm38.p6 Ensembl7135,537,824 - 135,541,195 (+)Ensembl
RefSeq Acc Id: ENSMUST00000209979   ⟹   ENSMUSP00000147613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,253,666 - 135,288,022 (+)Ensembl
GRCm38.p6 Ensembl7135,651,937 - 135,686,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210833   ⟹   ENSMUSP00000147313
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,207,557 - 135,285,081 (+)Ensembl
GRCm38.p6 Ensembl7135,605,828 - 135,683,352 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211092
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,253,667 - 135,273,956 (+)Ensembl
GRCm38.p6 Ensembl7135,651,938 - 135,672,227 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211140   ⟹   ENSMUSP00000147957
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,139,210 - 135,288,022 (+)Ensembl
GRCm38.p6 Ensembl7135,537,481 - 135,686,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211788   ⟹   ENSMUSP00000147524
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7135,195,117 - 135,285,084 (+)Ensembl
GRCm38.p6 Ensembl7135,593,388 - 135,683,355 (+)Ensembl
RefSeq Acc Id: NM_001316678   ⟹   NP_001303607
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397135,139,553 - 135,288,023 (+)NCBI
GRCm387135,537,824 - 135,686,294 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001316679   ⟹   NP_001303608
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397135,207,557 - 135,288,023 (+)NCBI
GRCm387135,605,828 - 135,686,294 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001316680   ⟹   NP_001303609
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397135,195,210 - 135,288,023 (+)NCBI
GRCm387135,593,481 - 135,686,294 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001316681   ⟹   NP_001303610
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397135,253,628 - 135,288,023 (+)NCBI
GRCm387135,651,899 - 135,686,294 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011212   ⟹   NP_035342
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397135,139,553 - 135,288,023 (+)NCBI
GRCm387135,537,824 - 135,686,294 (+)NCBI
MGSCv377142,729,507 - 142,877,977 (+)RGD
Celera7135,360,562 - 135,509,397 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_001785494
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397135,139,195 - 135,288,023 (+)NCBI
GRCm387135,537,829 - 135,671,201 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035342   ⟸   NM_011212
- Peptide Label: isoform b precursor
- UniProtKB: Q64496 (UniProtKB/Swiss-Prot),   P49446 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001303607   ⟸   NM_001316678
- Peptide Label: isoform a
- UniProtKB: P49446 (UniProtKB/Swiss-Prot),   Q3V1H5 (UniProtKB/TrEMBL),   A0A1B0GRT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001303609   ⟸   NM_001316680
- Peptide Label: isoform c precursor
- UniProtKB: P49446 (UniProtKB/Swiss-Prot),   A0A1B0GRH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001303608   ⟸   NM_001316679
- Peptide Label: isoform b precursor
- UniProtKB: Q64496 (UniProtKB/Swiss-Prot),   P49446 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001303610   ⟸   NM_001316681
- Peptide Label: isoform d
- UniProtKB: P49446 (UniProtKB/Swiss-Prot),   Q3V1H5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000147524   ⟸   ENSMUST00000211788
RefSeq Acc Id: ENSMUSP00000073616   ⟸   ENSMUST00000073961
RefSeq Acc Id: ENSMUSP00000147957   ⟸   ENSMUST00000211140
RefSeq Acc Id: ENSMUSP00000147313   ⟸   ENSMUST00000210833
RefSeq Acc Id: ENSMUSP00000147613   ⟸   ENSMUST00000209979
RefSeq Acc Id: ENSMUSP00000147656   ⟸   ENSMUST00000209256
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49446-F1-model_v2 AlphaFold P49446 1-699 view protein structure

Promoters
RGD ID:8665915
Promoter ID:EPDNEW_M10988
Type:initiation region
Name:Ptpre_1
Description:Mus musculus protein tyrosine phosphatase, receptor type, E ,transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387135,651,938 - 135,651,998EPDNEW
RGD ID:6841886
Promoter ID:MM_KWN:53057
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Kidney
Transcripts:NM_011212
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367142,729,209 - 142,729,709 (+)MPROMDB
RGD ID:6841890
Promoter ID:MM_KWN:53060
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   MEF_B4,   MEF_B6
Transcripts:UC009KEG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367142,796,859 - 142,797,359 (+)MPROMDB
RGD ID:6841889
Promoter ID:MM_KWN:53062
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:UC009KEJ.1,   UC009KEK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367142,843,406 - 142,843,906 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97813 AgrOrtholog
Ensembl Genes ENSMUSG00000041836 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000073616 ENTREZGENE
  ENSMUSP00000073616.7 UniProtKB/Swiss-Prot
  ENSMUSP00000147313 ENTREZGENE
  ENSMUSP00000147313.2 UniProtKB/Swiss-Prot
  ENSMUSP00000147524 ENTREZGENE
  ENSMUSP00000147524.2 UniProtKB/TrEMBL
  ENSMUSP00000147613 ENTREZGENE
  ENSMUSP00000147613.2 UniProtKB/Swiss-Prot
  ENSMUSP00000147656 ENTREZGENE
  ENSMUSP00000147656.2 UniProtKB/TrEMBL
  ENSMUSP00000147957.2 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000073961 ENTREZGENE
  ENSMUST00000073961.8 UniProtKB/Swiss-Prot
  ENSMUST00000209256 ENTREZGENE
  ENSMUST00000209256.2 UniProtKB/TrEMBL
  ENSMUST00000209979 ENTREZGENE
  ENSMUST00000209979.2 UniProtKB/Swiss-Prot
  ENSMUST00000210833 ENTREZGENE
  ENSMUST00000210833.2 UniProtKB/Swiss-Prot
  ENSMUST00000211140.2 UniProtKB/Swiss-Prot
  ENSMUST00000211788 ENTREZGENE
  ENSMUST00000211788.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_rcpt_a/e-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19267 UniProtKB/Swiss-Prot
MGD MGI:97813 ENTREZGENE
NCBI Gene 19267 ENTREZGENE
PANTHER RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptpre PhenoGen
PIRSF PTPR_alpha_epsilon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GRH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GRT6 ENTREZGENE, UniProtKB/TrEMBL
  P49446 ENTREZGENE, UniProtKB/Swiss-Prot
  Q05CJ9_MOUSE UniProtKB/TrEMBL
  Q3TU63_MOUSE UniProtKB/TrEMBL
  Q3V1H5 ENTREZGENE, UniProtKB/TrEMBL
  Q64496 ENTREZGENE
UniProt Secondary Q3U369 UniProtKB/Swiss-Prot
  Q60986 UniProtKB/Swiss-Prot
  Q61042 UniProtKB/Swiss-Prot
  Q62134 UniProtKB/Swiss-Prot
  Q62444 UniProtKB/Swiss-Prot
  Q64496 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-16 Ptpre  protein tyrosine phosphatase receptor type E  Ptpre  protein tyrosine phosphatase, receptor type, E  Symbol and/or name change 5135510 APPROVED