Or5m8 (olfactory receptor family 5 subfamily M member 8) - Rat Genome Database

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Gene: Or5m8 (olfactory receptor family 5 subfamily M member 8) Mus musculus
Analyze
Symbol: Or5m8
Name: olfactory receptor family 5 subfamily M member 8
RGD ID: 1551680
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR5M8 (olfactory receptor family 5 subfamily M member 8).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2Q125-47470765-47471775; MOR200; MOR200-1; olfactory receptor 1031; olfactory receptor MOR200-1; Olfr1031
RGD Orthologs
Human
Rat
Dog
Squirrel
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39285,822,163 - 85,823,173 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl285,820,648 - 85,824,048 (+)EnsemblGRCm39 Ensembl
GRCm38285,991,819 - 85,992,829 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,990,304 - 85,993,704 (+)EnsemblGRCm38mm10GRCm38
MGSCv37285,831,976 - 85,832,986 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36285,792,658 - 85,793,668 (+)NCBIMGSCv36mm8
Celera287,575,471 - 87,576,481 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or5m8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39285,822,163 - 85,823,173 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl285,820,648 - 85,824,048 (+)EnsemblGRCm39 Ensembl
GRCm38285,991,819 - 85,992,829 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,990,304 - 85,993,704 (+)EnsemblGRCm38mm10GRCm38
MGSCv37285,831,976 - 85,832,986 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36285,792,658 - 85,793,668 (+)NCBIMGSCv36mm8
Celera287,575,471 - 87,576,481 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.69NCBI
OR5M8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,490,435 - 56,491,370 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,490,435 - 56,491,370 (-)EnsemblGRCh38hg38GRCh38
GRCh371156,257,911 - 56,258,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,014,487 - 56,015,422 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,014,486 - 56,015,422NCBI
Celera1153,605,589 - 53,606,524 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1152,594,792 - 52,595,727 (-)NCBIHuRef
CHM1_11156,124,180 - 56,125,115 (-)NCBICHM1_1
T2T-CHM13v2.01156,428,361 - 56,429,296 (-)NCBIT2T-CHM13v2.0
Or5m8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8391,439,317 - 91,442,419 (+)NCBIGRCr8
mRatBN7.2371,034,767 - 71,035,750 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl371,021,820 - 71,036,238 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx374,419,446 - 74,420,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0383,017,982 - 83,018,965 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0380,801,151 - 80,802,134 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0373,352,352 - 73,353,335 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl373,352,352 - 73,353,335 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0379,920,908 - 79,921,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4369,204,582 - 69,205,565 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1369,100,953 - 69,101,937 (+)NCBI
Celera370,365,403 - 70,366,386 (+)NCBICelera
Cytogenetic Map3q24NCBI
OR5M8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11839,449,732 - 39,450,670 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1839,449,750 - 39,450,670 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,995,207 - 38,996,142 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01840,126,679 - 40,127,614 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1840,126,694 - 40,127,614 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11839,732,032 - 39,732,967 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01839,299,239 - 39,300,174 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01839,882,034 - 39,882,969 (+)NCBIUU_Cfam_GSD_1.0
LOC101976744
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494715,933,249 - 15,934,214 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365816,047,095 - 6,048,051 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365816,047,071 - 6,048,036 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0

Variants

.
Variants in Or5m8
30 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:104
Interacting mature miRNAs:107
Transcripts:ENSMUST00000050942
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
1301897Scc2_mcolon tumor susceptibility 2 (mouse)Not determined28572426990410991Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000050942   ⟹   ENSMUSP00000059256
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl285,822,163 - 85,823,173 (+)Ensembl
GRCm38.p6 Ensembl285,991,819 - 85,992,829 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216807   ⟹   ENSMUSP00000149225
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl285,820,648 - 85,824,048 (+)Ensembl
GRCm38.p6 Ensembl285,990,304 - 85,993,704 (+)Ensembl
RefSeq Acc Id: NM_001011759   ⟹   NP_001011759
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39285,822,163 - 85,823,173 (+)NCBI
GRCm38285,991,819 - 85,992,829 (+)ENTREZGENE
MGSCv37285,831,976 - 85,832,986 (+)RGD
Celera287,575,471 - 87,576,481 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001011759 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP71478 (Get FASTA)   NCBI Sequence Viewer  
  EDL27347 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000059256
  ENSMUSP00000059256.3
  ENSMUSP00000149225.2
Reference Protein Sequences
RefSeq Acc Id: NP_001011759   ⟸   NM_001011759
- UniProtKB: Q7TR87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059256   ⟸   ENSMUST00000050942
RefSeq Acc Id: ENSMUSP00000149225   ⟸   ENSMUST00000216807
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TR87-F1-model_v2 AlphaFold Q7TR87 1-336 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030865 AgrOrtholog
Ensembl Genes ENSMUSG00000043267 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000050942 ENTREZGENE
  ENSMUST00000050942.3 UniProtKB/TrEMBL
  ENSMUST00000216807.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:257916 UniProtKB/TrEMBL
MGD MGI:3030865 ENTREZGENE
NCBI Gene 257916 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5m8 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TR87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5m8  olfactory receptor family 5 subfamily M member 8  Olfr1031  olfactory receptor 1031  Symbol and/or name change 5135510 APPROVED