Nat8f1 (N-acetyltransferase 8 (GCN5-related) family member 1) - Rat Genome Database

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Gene: Nat8f1 (N-acetyltransferase 8 (GCN5-related) family member 1) Mus musculus
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Symbol: Nat8f1
Name: N-acetyltransferase 8 (GCN5-related) family member 1
RGD ID: 1551627
MGI Page MGI
Description: Predicted to enable cysteine-S-conjugate N-acetyltransferase activity and lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Predicted to be involved in several processes, including negative regulation of apoptotic process; peptide metabolic process; and peptidyl-lysine N6-acetylation. Predicted to act upstream of or within negative regulation of cell adhesion. Located in mitochondrial inner membrane. Is expressed in urinary system. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110002I11Rik; AI266962; camello-like 1; camello-like protein 1; Cml; cml1; probable N-acetyltransferase CML1
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Nat8b-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,887,136 - 85,893,210 (-)NCBIGRCm39mm39
GRCm39 Ensembl685,887,136 - 85,892,669 (-)Ensembl
GRCm38685,910,154 - 85,915,914 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,910,154 - 85,915,687 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,860,148 - 85,865,671 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,875,790 - 85,881,295 (-)NCBImm8
Celera687,844,498 - 87,850,024 (-)NCBICelera
Cytogenetic Map6C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12865426   PMID:16141072   PMID:16141073   PMID:18287559   PMID:21267068   PMID:21386911   PMID:21873635  
PMID:22267734   PMID:25123547  


Genomics

Comparative Map Data
Nat8f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,887,136 - 85,893,210 (-)NCBIGRCm39mm39
GRCm39 Ensembl685,887,136 - 85,892,669 (-)Ensembl
GRCm38685,910,154 - 85,915,914 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,910,154 - 85,915,687 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,860,148 - 85,865,671 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,875,790 - 85,881,295 (-)NCBImm8
Celera687,844,498 - 87,850,024 (-)NCBICelera
Cytogenetic Map6C3NCBI
Nat8f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24118,336,208 - 118,342,923 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl4118,332,862 - 118,344,035 (-)Ensembl
Rnor_6.04117,582,779 - 117,589,464 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,582,781 - 117,589,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,767,077 - 117,767,772 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04182,338,287 - 182,344,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,059,311 - 120,065,996 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4107,309,567 - 107,316,252 (-)NCBICelera
Cytogenetic Map4q34NCBI

Position Markers
AI266962  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38685,910,198 - 85,910,298UniSTSGRCm38
MGSCv37685,860,192 - 85,860,292UniSTSGRCm37
Celera687,844,542 - 87,844,642UniSTS
Cytogenetic Map6C3UniSTS
Whitehead/MRC_RH6882.69UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:672
Count of miRNA genes:464
Interacting mature miRNAs:538
Transcripts:ENSMUST00000161198, ENSMUST00000172982, ENSMUST00000174369
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000161198   ⟹   ENSMUSP00000124488
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,887,136 - 85,892,669 (-)Ensembl
GRCm38.p6 Ensembl685,910,154 - 85,915,687 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172982
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,887,144 - 85,892,648 (-)Ensembl
GRCm38.p6 Ensembl685,910,162 - 85,915,666 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174369   ⟹   ENSMUSP00000133475
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,887,612 - 85,892,586 (-)Ensembl
GRCm38.p6 Ensembl685,910,630 - 85,915,604 (-)Ensembl
RefSeq Acc Id: ENSMUST00000239124   ⟹   ENSMUSP00000158936
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,887,139 - 85,892,659 (-)Ensembl
GRCm38.p6 Ensembl685,910,157 - 85,915,677 (-)Ensembl
RefSeq Acc Id: NM_023160   ⟹   NP_075649
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,887,136 - 85,892,614 (-)NCBI
GRCm38685,910,154 - 85,915,632 (-)NCBI
MGSCv37685,860,148 - 85,865,671 (-)RGD
Celera687,844,498 - 87,850,024 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506470   ⟹   XP_006506533
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,887,136 - 85,893,210 (-)NCBI
GRCm38685,910,154 - 85,915,914 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_075649   ⟸   NM_023160
- Sequence:
RefSeq Acc Id: XP_006506533   ⟸   XM_006506470
- Peptide Label: isoform X1
- UniProtKB: E9PUL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000158936   ⟸   ENSMUST00000239124
RefSeq Acc Id: ENSMUSP00000133475   ⟸   ENSMUST00000174369
RefSeq Acc Id: ENSMUSP00000124488   ⟸   ENSMUST00000161198
Protein Domains
N-acetyltransferase

Promoters
RGD ID:6840117
Promoter ID:MM_KWN:46707
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000113751,   ENSMUST00000113752,   ENSMUST00000113753,   NM_023160,   NM_176842,   OTTMUST00000058259,   OTTMUST00000058261
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36685,864,966 - 85,866,517 (+)MPROMDB
RGD ID:6890256
Promoter ID:EPDNEW_M8579
Type:multiple initiation site
Name:Nat8f1_1
Description:Mus musculus N-acetyltransferase 8 (GCN5-related) family member1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38685,915,626 - 85,915,686EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913366 AgrOrtholog
Ensembl Genes ENSMUSG00000057103 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000124488 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000133475 UniProtKB/TrEMBL
  ENSMUSP00000158936 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000161198 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000174369 UniProtKB/TrEMBL
  ENSMUST00000239124 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GNAT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66116 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1913366 ENTREZGENE
NCBI Gene 66116 ENTREZGENE
Pfam Acetyltransf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nat8f1 PhenoGen
PROSITE GNAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CMLO1_MOUSE UniProtKB/Swiss-Prot
  E9PUL7 ENTREZGENE, UniProtKB/TrEMBL
  G3UWY7_MOUSE UniProtKB/TrEMBL
  Q9JIZ0 ENTREZGENE
UniProt Secondary Q91XE3 UniProtKB/Swiss-Prot
  Q9CW77 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-02 Nat8f1  N-acetyltransferase 8 (GCN5-related) family member 1  Cml1  camello-like 1  Symbol and/or name change 5135510 APPROVED