Mterf2 (mitochondrial transcription termination factor 2) - Rat Genome Database

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Gene: Mterf2 (mitochondrial transcription termination factor 2) Mus musculus
Analyze
Symbol: Mterf2
Name: mitochondrial transcription termination factor 2
RGD ID: 1551524
MGI Page MGI
Description: Predicted to have DNA binding activity. Predicted to be involved in termination of mitochondrial transcription. Localizes to mitochondrial nucleoid. Orthologous to human MTERF2 (mitochondrial transcription termination factor 2); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700007D05Rik; MTERF domain containing 3; mTERF domain-containing protein 3, mitochondrial; Mterfd; Mterfd3; transcription termination factor 2, mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391084,951,092 - 84,963,982 (-)NCBIGRCm39mm39
GRCm39 Ensembl1084,955,297 - 84,963,891 (-)Ensembl
GRCm381085,119,433 - 85,128,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1085,119,433 - 85,128,027 (-)EnsemblGRCm38mm10GRCm38
MGSCv371084,582,178 - 84,590,772 (-)NCBIGRCm37mm9NCBIm37
MGSCv361084,549,235 - 84,557,800 (-)NCBImm8
Celera1087,095,781 - 87,104,375 (-)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18614015   PMID:19366608   PMID:21677750  
PMID:21873635  


Genomics

Comparative Map Data
Mterf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391084,951,092 - 84,963,982 (-)NCBIGRCm39mm39
GRCm39 Ensembl1084,955,297 - 84,963,891 (-)Ensembl
GRCm381085,119,433 - 85,128,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1085,119,433 - 85,128,027 (-)EnsemblGRCm38mm10GRCm38
MGSCv371084,582,178 - 84,590,772 (-)NCBIGRCm37mm9NCBIm37
MGSCv361084,549,235 - 84,557,800 (-)NCBImm8
Celera1087,095,781 - 87,104,375 (-)NCBICelera
Cytogenetic Map10C1NCBI
MTERF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12106,977,277 - 106,987,160 (-)EnsemblGRCh38hg38GRCh38
GRCh3812106,972,856 - 106,987,166 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712107,371,055 - 107,380,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612105,895,199 - 105,905,059 (-)NCBINCBI36hg18NCBI36
Celera12107,036,630 - 107,046,488 (-)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12104,431,573 - 104,441,448 (-)NCBIHuRef
CHM1_112107,336,699 - 107,346,574 (-)NCBICHM1_1
Mterf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2718,598,202 - 18,608,278 (+)NCBI
Rnor_6.0 Ensembl724,638,208 - 24,648,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0724,638,208 - 24,649,599 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0724,788,242 - 24,798,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4720,713,326 - 20,723,489 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1720,733,596 - 20,743,756 (+)NCBI
Celera715,826,281 - 15,836,295 (+)NCBICelera
Cytogenetic Map7q13NCBI
Mterf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540540,870,215 - 40,871,384 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540540,870,002 - 40,871,433 (-)NCBIChiLan1.0ChiLan1.0
MTERF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112107,938,754 - 107,948,648 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12107,939,021 - 107,940,178 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012104,544,783 - 104,554,675 (-)NCBIMhudiblu_PPA_v0panPan3
MTERF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11031,792,889 - 31,794,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1031,792,917 - 31,794,074 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1031,765,709 - 31,780,579 (+)NCBI
ROS_Cfam_1.01032,621,587 - 32,636,444 (+)NCBI
UMICH_Zoey_3.11032,357,826 - 32,372,680 (+)NCBI
UNSW_CanFamBas_1.01032,648,303 - 32,663,103 (+)NCBI
UU_Cfam_GSD_1.01032,834,267 - 32,849,133 (+)NCBI
Mterf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494514,987,812 - 15,006,137 (+)NCBI
SpeTri2.0NW_0049364927,998,229 - 8,007,103 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTERF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl513,364,806 - 13,377,261 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1513,374,243 - 13,376,641 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2513,219,978 - 13,228,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MTERF2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111102,191,842 - 102,200,719 (-)NCBI
ChlSab1.1 Ensembl11102,190,413 - 102,191,567 (-)Ensembl
Mterf2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247502,535,015 - 2,555,789 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105125566085255809Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105125566085255809Mouse
14746991Manh68_mmandible shape 68 (mouse)105244466786444667Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105868113592681262Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106565510499655287Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106565510499655287Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106565510499655287Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106701240892422811Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078545406112545406Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082242550116242550Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082473556116473795Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082473556116473795Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082473556116473795Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082473556116473795Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082473556116473795Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082473556116473795Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082556941116557090Mouse
4141382Ssrq4_mstress response QTL 4 (mouse)Not determined8265510491020240Mouse
12910789Pwgrq19_mpost-weaning growth rate QTL 19 (mouse)108299286692333194Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83181141117181274Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084243786122205623Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84243786122205623Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84243786122205623Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084243786122205623Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084243786122205623Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:28
Interacting mature miRNAs:30
Transcripts:ENSMUST00000050813
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000050813   ⟹   ENSMUSP00000062762
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1085,119,433 - 85,128,027 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214193   ⟹   ENSMUSP00000150091
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1085,120,610 - 85,127,995 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214607   ⟹   ENSMUSP00000150772
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1085,120,548 - 85,126,577 (-)Ensembl
RefSeq Acc Id: ENSMUST00000217027   ⟹   ENSMUSP00000150699
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1085,120,499 - 85,128,027 (-)Ensembl
RefSeq Acc Id: NM_001379524   ⟹   NP_001366453
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391084,955,305 - 84,963,879 (-)NCBI
GRCm381085,119,441 - 85,128,015 (-)NCBI
RefSeq Acc Id: NM_001379525   ⟹   NP_001366454
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391084,955,305 - 84,963,879 (-)NCBI
GRCm381085,119,441 - 85,128,015 (-)NCBI
RefSeq Acc Id: NM_001379526   ⟹   NP_001366455
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391084,955,305 - 84,963,879 (-)NCBI
GRCm381085,119,441 - 85,128,015 (-)NCBI
RefSeq Acc Id: NM_028832   ⟹   NP_083108
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391084,955,297 - 84,963,891 (-)NCBI
GRCm381085,119,433 - 85,128,027 (-)NCBI
MGSCv371084,582,178 - 84,590,772 (-)RGD
Celera1087,095,781 - 87,104,375 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030245330   ⟹   XP_030101190
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391084,951,092 - 84,963,982 (-)NCBI
GRCm381085,119,441 - 85,127,972 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083108   ⟸   NM_028832
- Peptide Label: precursor
- UniProtKB: Q8BKY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030101190   ⟸   XM_030245330
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001366455   ⟸   NM_001379526
- Peptide Label: precursor
RefSeq Acc Id: NP_001366454   ⟸   NM_001379525
- Peptide Label: precursor
RefSeq Acc Id: NP_001366453   ⟸   NM_001379524
- Peptide Label: precursor
RefSeq Acc Id: ENSMUSP00000150699   ⟸   ENSMUST00000217027
RefSeq Acc Id: ENSMUSP00000062762   ⟸   ENSMUST00000050813
RefSeq Acc Id: ENSMUSP00000150772   ⟸   ENSMUST00000214607
RefSeq Acc Id: ENSMUSP00000150091   ⟸   ENSMUST00000214193

Promoters
RGD ID:6819626
Promoter ID:MM_KWN:5153
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_028832
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361084,590,629 - 84,591,129 (-)MPROMDB
RGD ID:8672910
Promoter ID:EPDNEW_M14486
Type:initiation region
Name:Mterf2_1
Description:Mus musculus mitochondrial transcription termination factor 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381085,127,986 - 85,128,046EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921488 AgrOrtholog
Ensembl Genes ENSMUSG00000049038 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000062762 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000150091 UniProtKB/TrEMBL
  ENSMUSP00000150699 UniProtKB/TrEMBL
  ENSMUSP00000150772 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000050813 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000214193 UniProtKB/TrEMBL
  ENSMUST00000214607 UniProtKB/TrEMBL
  ENSMUST00000217027 UniProtKB/TrEMBL
Gene3D-CATH 1.25.70.10 UniProtKB/Swiss-Prot
InterPro MTERF UniProtKB/Swiss-Prot
  MTERF_sf UniProtKB/Swiss-Prot
KEGG Report mmu:74238 UniProtKB/Swiss-Prot
MGD MGI:1921488 ENTREZGENE
NCBI Gene 74238 ENTREZGENE
Pfam mTERF UniProtKB/Swiss-Prot
PhenoGen Mterf2 PhenoGen
SMART Mterf UniProtKB/Swiss-Prot
UniProt A0A1L1SSZ1_MOUSE UniProtKB/TrEMBL
  A0A1L1SUB1_MOUSE UniProtKB/TrEMBL
  A0A1L1SUH9_MOUSE UniProtKB/TrEMBL
  MTEF2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-08-05 Mterf2  mitochondrial transcription termination factor 2  Mterfd3  MTERF domain containing 3  Symbol and/or name change 5135510 APPROVED