Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of HRNR mRNA | CTD | PMID:28960355 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HRNR mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | HRNR (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of HRNR mRNA | CTD | PMID:21835898 and PMID:23152189 | 2-hydroxypropanoic acid | decreases expression | ISO | HRNR (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of HRNR mRNA | CTD | PMID:30851411 | benzo[a]pyrene | increases methylation | ISO | HRNR (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HRNR 5' UTR and Benzo(a)pyrene results in increased methylation of HRNR promoter | CTD | PMID:27901495 | beta-damascenone | increases expression | EXP | | 6480464 | beta-damascenone results in increased expression of HRNR mRNA | CTD | PMID:22982537 | cadmium atom | affects binding | ISO | HRNR (Homo sapiens) | 6480464 | HRNR protein binds to Cadmium | CTD | PMID:23896426 | cisplatin | multiple interactions | ISO | HRNR (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of HRNR mRNA | CTD | PMID:27392435 | dioxygen | decreases expression | EXP | | 6480464 | Oxygen deficiency results in decreased expression of HRNR mRNA | CTD | PMID:24205000 | enzyme inhibitor | multiple interactions | ISO | HRNR (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of HRNR protein | CTD | PMID:23301498 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of HRNR mRNA | CTD | PMID:25629700 | ivermectin | decreases expression | ISO | HRNR (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of HRNR protein | CTD | PMID:32959892 | lead(0) | affects binding | ISO | HRNR (Homo sapiens) | 6480464 | HRNR protein binds to Lead | CTD | PMID:23896426 | nickel atom | affects binding | ISO | HRNR (Homo sapiens) | 6480464 | HRNR protein binds to Nickel | CTD | PMID:23896426 | potassium dichromate | increases expression | ISO | HRNR (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of HRNR protein | CTD | PMID:23718831 | rac-lactic acid | decreases expression | ISO | HRNR (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of HRNR mRNA | CTD | PMID:30851411 | zinc atom | affects binding | ISO | HRNR (Homo sapiens) | 6480464 | HRNR protein binds to Zinc | CTD | PMID:23896426 | zinc(0) | affects binding | ISO | HRNR (Homo sapiens) | 6480464 | HRNR protein binds to Zinc | CTD | PMID:23896426 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Cellular Component
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Molecular Function
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Phenotype Annotations
Click to see Annotation Detail View
References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11572870 | PMID:12477932 | PMID:12642627 | PMID:15203200 | PMID:16141072 | PMID:16141073 | PMID:21267068 | PMID:21873635 | PMID:23439395 |
| PMID:24029230 | PMID:26644517 | PMID:28916756 | PMID:29459677 | PMID:30828807 | PMID:30973865 | PMID:31479664 | PMID:31823782 |
Genomics
Comparative Map Data
| Hrnr (Mus musculus - house mouse) |
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| HRNR (Homo sapiens - human) |
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| Hrnr (Rattus norvegicus - Norway rat) |
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| HRNR (Pan paniscus - bonobo/pygmy chimpanzee) |
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| LOC119863999 (Canis lupus familiaris - dog) |
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| HRNR (Sus scrofa - pig) |
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| HRNR (Chlorocebus sabaeus - green monkey) |
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Variants
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Variants in Hrnr
281 total Variants 
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