Plscr2 (phospholipid scramblase 2)

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Gene: Plscr2 (phospholipid scramblase 2) Mus musculus

Analyze

Symbol:

Plscr2

Name:

phospholipid scramblase 2

RGD ID:

1551464

MGI Page

MGI

Description:

Predicted to have phospholipid scramblase activity. Involved in cellular response to lipopolysaccharide. Localizes to cytoplasm and nucleus. Is expressed in foregut; inner ear; mesothelium; and urogenital mesentery. Orthologous to human PLSCR1 (phospholipid scramblase 1) and PLSCR2 (phospholipid scramblase 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

ca(2+)-dependent phospholipid scramblase 2; PL scramblase 2

RGD Orthologs

Human

Rat

Bonobo

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLSCR2 (phospholipid scramblase 2)	HGNC	Ensembl, HGNC, Panther, Treefam
Rattus norvegicus (Norway rat):	Plscr2 (phospholipid scramblase 2)	HGNC	Panther
Pan paniscus (bonobo/pygmy chimpanzee):	PLSCR2 (phospholipid scramblase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PLSCR1 (phospholipid scramblase 1)	HGNC	Ensembl, OrthoDB, OrthoMCL, Panther, Treefam
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Plscr1 (phospholipid scramblase 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Homo sapiens (human):	PLSCR1 (phospholipid scramblase 1)	Alliance	DIOPT (OMA\|OrthoInspector\|PANTHER\|TreeFam)
Homo sapiens (human):	PLSCR2 (phospholipid scramblase 2)	Alliance	DIOPT (HGNC\|OMA\|PANTHER\|TreeFam)
Danio rerio (zebrafish):	si:ch211-71m22.1	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Danio rerio (zebrafish):	plscr3b (phospholipid scramblase 3b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	si:ch73-206p6.1	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	AIM25	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	scramb1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	scramb2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	scrm-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	scrm-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	scrm-5	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	scrm-6	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	scrm-8	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	92,157,655 - 92,179,805 (+)	NCBI	GRCm39		mm39
GRCm38	9	92,275,602 - 92,297,752 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	92,275,602 - 92,297,752 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	92,170,558 - 92,192,569 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	92,079,491 - 92,101,502 (+)	NCBI			mm8
Celera	9	91,863,214 - 91,885,598 (+)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-isobutyl-1-methyl-7H-xanthine (EXP)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (EXP)

bisphenol A (EXP)

carbon nanotube (EXP)

chrysene (EXP)

ciguatoxin CTX1B (EXP)

copper atom (EXP)

copper(0) (EXP)

cyclosporin A (EXP)

dexamethasone (EXP)

dioxygen (EXP)

lipopolysaccharide (EXP)

mono(2-ethylhexyl) phthalate (EXP)

paracetamol (EXP)

paraquat (EXP)

phenobarbital (EXP)

pirinixic acid (EXP)

sodium arsenite (ISO)

succimer (EXP)

tetrachloromethane (EXP)

tetraphene (EXP)

titanium dioxide (EXP)

trimellitic anhydride (EXP)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to lipopolysaccharide (IEP)

phosphatidylserine exposure on apoptotic cell surface (IBA)

plasma membrane phospholipid scrambling (IBA)

Cellular Component

cytoplasm (IDA)

endoplasmic reticulum (ISO)

integral component of membrane (IEA)

intracellular membrane-bounded organelle (ISO)

membrane (IEA)

nucleoplasm (ISO)

nucleus (IDA)

plasma membrane (IBA)

Molecular Function

metal ion binding (IEA)

phospholipid scramblase activity (IBA)

protein binding (IPI)

SH3 domain binding (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal circulating free fatty acids level (IEA)

abnormal circulating iron level (IEA)

References

References - curated


1.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGD data from the GO Consortium
3.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	RGD automated import pipeline
5.	RGD automated import pipeline for gene-chemical interactions
6.	Wiedmer T, etal., Biochim Biophys Acta 2000 Jul 31;1467(1):244-53.
7.	Zhou Q, etal., Biochemistry 1998 Feb 24;37(8):2356-60.

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11591653	PMID:12477932	PMID:12509439	PMID:15489334	PMID:16141072	PMID:16141073	PMID:16919269	PMID:17590392	PMID:21267068
PMID:21677750	PMID:21873635	PMID:27626380

Genomics

Comparative Map Data

Plscr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	92,157,655 - 92,179,805 (+)	NCBI	GRCm39		mm39
GRCm38	9	92,275,602 - 92,297,752 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	92,275,602 - 92,297,752 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	92,170,558 - 92,192,569 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	92,079,491 - 92,101,502 (+)	NCBI			mm8
Celera	9	91,863,214 - 91,885,598 (+)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI

PLSCR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	146,391,421 - 146,495,991 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	146,391,363 - 146,497,163 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	146,109,150 - 146,213,778 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	147,633,772 - 147,696,412 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	147,633,779 - 147,696,420	NCBI
Celera	3	144,568,109 - 144,630,745 (-)	NCBI
Cytogenetic Map	3	q24	NCBI
HuRef	3	143,527,951 - 143,590,609 (-)	NCBI		HuRef
CHM1_1	3	146,114,147 - 146,176,844 (-)	NCBI		CHM1_1

Plscr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	8	99,650,351 - 99,725,514 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	99,625,545 - 99,725,217 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	99,199,390 - 99,210,708 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	97,231,930 - 97,274,354 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	8	97,251,384 - 97,293,808 (+)	NCBI
Celera	8	92,333,271 - 92,365,393 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

PLSCR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	151,029,759 - 151,140,481 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	151,029,766 - 151,092,437 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	143,446,683 - 143,509,767 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142042	Alpq3_m	alcohol preference QTL 3 (mouse)			Not determined		9	37394901	98819654	Mouse
4141224	Dxmod_m	doxorubicin nephropathy modifier (mouse)			Not determined			49541121	101528921	Mouse
1301241	Renf1_m	renal failure 1 (mouse)			Not determined		9	52123178	99910428	Mouse
1301172	Fembrs6_m	femur breaking strength 6 (mouse)			Not determined		9	59117105	93117252	Mouse
1301803	Stheal9_m	soft tissue heal 9 (mouse)			Not determined		9	59117105	93117252	Mouse
5491195	Mobq8_m	multigenic obesity QTL 8 (mouse)			Not determined		9	59462664	93462846	Mouse
1300848	Skull13_m	skull morphology 13 (mouse)			Not determined		9	59462664	93462846	Mouse
1301456	Adip5_m	adiposity 5 (mouse)			Not determined		9	59462664	93462846	Mouse
13207569	Tcq13_m	total cholesterol QTL 13 (mouse)					9	59990000	109260000	Mouse
1301611	Lrnx3_m	learning contextual 3 (mouse)			Not determined		9	62242485	96242599	Mouse
4141833	W10q13_m	weight 10 weeks QTL 13 (mouse)			Not determined			63332429	120362868	Mouse
4141545	Tailaq2_m	tail length adjusted QTL 2 (mouse)			Not determined			63332429	120362868	Mouse
1357635	Splq4_m	spleen weight QTL 4 (mouse)			Not determined		9	63332429	120362868	Mouse
11081165	Psl6_m	promotion susceptibility QTL 6 (mouse)					9	65133909	95640755	Mouse
1301636	Lith5_m	lithogenic gene 5 (mouse)			Not determined		9	66207024	100207122	Mouse
10045638	Heal29_m	wound healing/regeneration 29 (mouse)			Not determined		9	67124167	101124167	Mouse
1357610	Vtbt8_m	vertebral trabecular bone trait 8 (mouse)			Not determined		9	68897510	102897652	Mouse
1301924	Bmd10_m	bone mineral density 10 (mouse)			Not determined		9	68897510	102897652	Mouse
1301302	Pas4_m	pulmonary adenoma susceptibility 4 (mouse)			Not determined		9	69239845	103239920	Mouse
10412174	Habiir4_m	hyperoxic acute lung injury imprinted region 4 (mouse)			Not determined		9	69360465	98819654	Mouse
1301621	Hpic1_m	haloperidol-induced catalepsy 1 (mouse)			Not determined		9	69546513	103546645	Mouse
1301573	Etohcta8_m	ethanol conditioned taste aversion 8 (mouse)			Not determined		9	72977005	106977152	Mouse
10054068	El8_m	epilepsy 8 (mouse)			Not determined		9	72977005	106977152	Mouse
1301725	Lifespan1_m	life span 1 (mouse)			Not determined		9	74368177	108368325	Mouse
1302065	El1_m	epilepsy 1 (mouse)			Not determined		9	75775364	114474379	Mouse
10054492	El7_m	epilepsy 7 (mouse)			Not determined		9	75775364	114474379	Mouse
1301869	Tbbmd4_m	total body bone mineral density 4 (mouse)			Not determined		9	76117105	101528921	Mouse
1301407	Rapop2_m	radiation-induced apoptosis 2 (mouse)			Not determined		9	76535936	110536130	Mouse
1301192	Skts6_m	skin tumor susceptibility 6 (mouse)			Not determined		9	78640645	112640755	Mouse
10401247	Bglu14_m	blood glucose level 14 (mouse)			Not determined		9	79397810	113397888	Mouse
1301732	Char1_m	P. chabaudi malaria resistance QTL 1 (mouse)			Not determined		9	81798268	115798392	Mouse
1300884	Sluc11_m	susceptibility to lung cancer 11 (mouse)			Not determined		9	82910333	116910428	Mouse
1357461	Idd2_m	insulin dependent diabetes susceptibility 2 (mouse)			Not determined		9	82910333	116910428	Mouse
10766454	Char10_m	P. chabaudi malaria resistance QTL 10 (mouse)					9	82910333	116910428	Mouse
1301487	Nociq1_m	nociceptive sensitivity inflammatory QTL 1 (mouse)			Not determined		9	84528818	118528921	Mouse
10412180	Msam3_m	muscle, skeletal, activity measure 3 (mouse)			Not determined		9	85897510	108641186	Mouse
1300549	Bbaa17_m	B. burgdorferi-associated arthritis 17 (mouse)			Not determined		9	86230401	120230530	Mouse
1302103	Dob2_m	dietary obesity 2 (mouse)			Not determined		9	86239845	120289624	Mouse
11251716	Siim2_m	stress induced immobility 2 (mouse)					9	86748483	120748483	Mouse
12880422	V25Dq6_m	vitamin D inactive form serum level QTL 6 (mouse)					9	87800000	121800000	Mouse
10412242	Alpq8_m	alcohol preference QTL 8 (mouse)			Not determined		9	89284925	123284925	Mouse
1301649	Psl1_m	promotion susceptibility QTL 1 (mouse)			Not determined		9	89412277	123412396	Mouse
18182932	Metl3_m	metabolite locus 3, N-acetylglutamate (mouse)					9	89563342	123563342	Mouse
1357657	Pymr_m	Plasmodium yoelli malaria resistance (mouse)			Not determined		9	89977005	118938021	Mouse
12910770	Splic1_m	spleen iron content 1 (mouse)					9	91413879	124595110	Mouse
12910772	Lvic6_m	liver iron content 6 (mouse)					9	91413879	124595110	Mouse
12910773	Splic3_m	spleen iron content 3 (mouse)					9	91413879	124595110	Mouse
1558767	Skmw11_m	skeletal muscle weight 11 (mouse)			Not determined		9	91641084	124595110	Mouse
13463474	Hbbcq5_m	hemoglobin concentration QTL 5 (mouse)					9	91641084	124595110	Mouse
13463475	Hctq7_m	hematocrit QTL 7 (mouse)					9	91641084	124595110	Mouse
13463477	Rbc9_m	red blood cell count 9 (mouse)					9	91641084	124595110	Mouse
13463478	Mchq18_m	mean corpuscular hemoglobin QTL 18 (mouse)					9	91641084	124595110	Mouse
13463480	Mchcq2_m	mean corpuscular hemoglobin concentration QTL 2 (mouse)					9	91641084	124595110	Mouse
12904937	Edlmmq9_m	extensor digitorum longus muscle mass QTL 9 (mouse)					9	91683173	124595110	Mouse
12904947	Tammq7_m	tibialis anterior muscle mass QTL 7 (mouse)					9	91683173	124595110	Mouse
12904961	Gmmq7_m	gastrocnemius muscle mass QTL 7 (mouse)					9	91683173	124595110	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	391
Count of miRNA genes:	187
Interacting mature miRNAs:	197
Transcripts:	ENSMUST00000034932, ENSMUST00000113044, ENSMUST00000126911, ENSMUST00000156772, ENSMUST00000180154
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001195084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_008880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006510857	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011242676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC111125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF015790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW261539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC002012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC011299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000034932 ⟹ ENSMUSP00000034932

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	92,275,602 - 92,297,731 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000113044 ⟹ ENSMUSP00000108667

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	92,289,572 - 92,297,731 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000126911 ⟹ ENSMUSP00000119104

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	92,275,746 - 92,282,192 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000156772

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	92,290,819 - 92,291,784 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000180154 ⟹ ENSMUSP00000136481

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	92,275,602 - 92,297,752 (+)	Ensembl

RefSeq Acc Id:

NM_001195084 ⟹ NP_001182013

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	92,157,655 - 92,179,805 (+)	NCBI
GRCm38	9	92,275,602 - 92,297,752 (+)	ENTREZGENE
Celera	9	91,863,096 - 91,885,619 (+)	ENTREZGENE
cM Map	9		ENTREZGENE

Sequence:

show sequence

GGAAAGCATTCCTGAGTCTCCTTTTGAATCAGTGCCAGCATTTGAAGAATGCAGTGGAGGTCAG
AGTAAAGGGAATGCCAGTAAGTGTTCCTTTGGCGTTCCAGAACTGTGCACAGACCAGATATTCA
TTTCTACTGAGAGCCTCTGCCAGGAGCAGCTAACAATTCTCAAAGGACTTAGAACTCAGACAGG
GTTTCAATTTGGTTGCGTATCTTTCCAGTCAGGAAAAGGAAATCTAAAGACTCAGGAAACAAAA
CCTAAACTGCCTCAAAGTCCAGGTGCTTTTTCTCCCTGACTTTAGTCTAGTGGAGTAGTGCAGC
ACCTATGCCTTTCTGAGAGGAGTCTGGAGAGCTGAGTCGCTGCTGGTGCTAGGATTCTAGGAAT
TCGCCTCACTTGGAGCTGCATGAGAAAGGAAAGGCTTGCAAATGGAGGCTCCTCGCTCAGGAAC
ATACTTGCCAGCTGGGTATGCCCCTCAGTATCCTCCAGCAGCAGTCCAAGGACCTCCAGAGCAT
ACTGGACGCCCCACATTCCAGACTAACTACCAAGTTCCCCAGTCTGGTTATCCAGGACCTCAGG
CTAGCTACACAGTCTCAACATCTGGACATGAAGGTTATGCTGCTACACGGCTTCCTATTCAAAA
TAATCAGACTATAGTCCTTGCAAACACTCAGTGGATGCCAGCACCACCACCTATTCTGAACTGC
CCACCTGGGCTAGAATACTTAAATCAGATAGATCAGCTTCTGATTCATCAGCAAGTTGAACTTC
TAGAAGTCTTAACAGGCTTTGAAACAAATAACAAATTTGAAATCAAGAACAGCCTCGGGCAGAT
GGTTTATGTTGCAGTGGAAGATACTGACTGCTGTACTCGAAATTGCTGTGAAGCGTCTAGACCT
TTCACTTTAAGAATCCTGGATCATCTGGGCCAAGAAGTCATGACTCTGGAGAGACCTCTGAAAT
GCAGTAGCTGCTGCTTCCCTTGCTGCCTCCAGGAGATAGAAATCCAGGCTCCTCCAGGGGTGCC
AATAGGTTATGTGACTCAGACCTGGCACCCATGTCTGCCAAAGCTCACTCTTCAGAACGACAAG
AGGGAGAATGTTCTAAAAGTAGTTGGTCCATGTGTTGCATGCACCTGCTGTTCAGATATTGACT
TTGAGATCAAGTCTCTTGATGAAGTGACTAGAATTGGTAAGATCACCAAGCAGTGGTCTGGTTG
TGTGAAAGAGGCCTTCACGGATTCGGATAACTTTGGGATCCAATTCCCGCTAGACCTGGAGGTG
AAGATGAAAGCTGTGACGCTTGGTGCTTGCTTCCTCATAGATTACATGTTTTTTGAAGGCTGTG
AGTAGGAACAGAAATCCGACCTGCAGTAGGAATCAATGAAAGAGGACAGAGAAGATCTGAAGTC
TACACAAGGAGATCATATGATTGAGAGACCTGGGGCTTTTTGATTTCTTCATTGAAATTTCTCA
GAATCAAGCTGTTATACATGAAGCATAGTATGTAACATTTTGGTTTTCAAATGGTAGTTTATCT
TTTACATTATTGGAATAGACCTGGATAATTATCTTTATACACTTCTAAAAATATGCACCAAATT
CAAGTTAAAAAAAAAAGACGAAGAGAAGTGTATGTTTTAAAATAAAACATTTTATGGAAAAGTA
AGTTAAATCATAATCTTTGATTTATTTTTCATCTTTTGTTCAATTTAAACCTTGTTAGTGCTGA
TTTTATTATAAAATTGTACTTTACTATCAAACCTAGTTAGTTTATTTCTTACAGAAATCCTCCT
ATTATTTTGAAATTACATATTTTTGAAAGCTTTTTAAAAGATACTATTGCCTGGGAAATTCTAT
TCAATAAAATGCTAATGAGAAAAGATAGTGTGTACTTTCTTCCA

hide sequence

RefSeq Acc Id:

NM_008880 ⟹ NP_032906

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	92,157,655 - 92,179,805 (+)	NCBI
GRCm38	9	92,275,602 - 92,297,752 (+)	ENTREZGENE
MGSCv37	9	92,170,558 - 92,192,569 (+)	RGD
Celera	9	91,863,096 - 91,885,619 (+)	ENTREZGENE
cM Map	9		ENTREZGENE

Sequence:

show sequence

GGAAAGCATTCCTGAGTCTCCTTTTGAATCAGTGCCAGCATTTGAAGAATGCAGTGGAGGTCAG
AGTAAAGGGAATGCCAGTAAGTGTTCCTTTGGCGTTCCAGAACTGTGCACAGACCAGATATTCA
TTTCTACTGAGAGCCTCTGCCAGGAGCAGCTAACAATTCTCAAAGGACTTAGAACTCAGACAGG
GTTTCAATTTGGTTGCGTATCTTTCCAGTCAGGAAAAGGAAATCTAAAGACTCAGGAAACAAAA
CCTAAACTGCCTCAAAGTCCAGGTGCTTTTTCTCCCTGACTTTAGTCTAGTGGAGTAGTGCAGC
ACCTATGCCTTTCTGAGAGGAGTCTGGAGAGCTGAGTCGCTGCTGGTGCTAGGATTCTAGGAAT
TCGCCTCACTTGGAGCTGCATGAGAAAGGCTTGCAAATGGAGGCTCCTCGCTCAGGAACATACT
TGCCAGCTGGGTATGCCCCTCAGTATCCTCCAGCAGCAGTCCAAGGACCTCCAGAGCATACTGG
ACGCCCCACATTCCAGACTAACTACCAAGTTCCCCAGTCTGGTTATCCAGGACCTCAGGCTAGC
TACACAGTCTCAACATCTGGACATGAAGGTTATGCTGCTACACGGCTTCCTATTCAAAATAATC
AGACTATAGTCCTTGCAAACACTCAGTGGATGCCAGCACCACCACCTATTCTGAACTGCCCACC
TGGGCTAGAATACTTAAATCAGATAGATCAGCTTCTGATTCATCAGCAAGTTGAACTTCTAGAA
GTCTTAACAGGCTTTGAAACAAATAACAAATTTGAAATCAAGAACAGCCTCGGGCAGATGGTTT
ATGTTGCAGTGGAAGATACTGACTGCTGTACTCGAAATTGCTGTGAAGCGTCTAGACCTTTCAC
TTTAAGAATCCTGGATCATCTGGGCCAAGAAGTCATGACTCTGGAGAGACCTCTGAAATGCAGT
AGCTGCTGCTTCCCTTGCTGCCTCCAGGAGATAGAAATCCAGGCTCCTCCAGGGGTGCCAATAG
GTTATGTGACTCAGACCTGGCACCCATGTCTGCCAAAGCTCACTCTTCAGAACGACAAGAGGGA
GAATGTTCTAAAAGTAGTTGGTCCATGTGTTGCATGCACCTGCTGTTCAGATATTGACTTTGAG
ATCAAGTCTCTTGATGAAGTGACTAGAATTGGTAAGATCACCAAGCAGTGGTCTGGTTGTGTGA
AAGAGGCCTTCACGGATTCGGATAACTTTGGGATCCAATTCCCGCTAGACCTGGAGGTGAAGAT
GAAAGCTGTGACGCTTGGTGCTTGCTTCCTCATAGATTACATGTTTTTTGAAGGCTGTGAGTAG
GAACAGAAATCCGACCTGCAGTAGGAATCAATGAAAGAGGACAGAGAAGATCTGAAGTCTACAC
AAGGAGATCATATGATTGAGAGACCTGGGGCTTTTTGATTTCTTCATTGAAATTTCTCAGAATC
AAGCTGTTATACATGAAGCATAGTATGTAACATTTTGGTTTTCAAATGGTAGTTTATCTTTTAC
ATTATTGGAATAGACCTGGATAATTATCTTTATACACTTCTAAAAATATGCACCAAATTCAAGT
TAAAAAAAAAAGACGAAGAGAAGTGTATGTTTTAAAATAAAACATTTTATGGAAAAGTAAGTTA
AATCATAATCTTTGATTTATTTTTCATCTTTTGTTCAATTTAAACCTTGTTAGTGCTGATTTTA
TTATAAAATTGTACTTTACTATCAAACCTAGTTAGTTTATTTCTTACAGAAATCCTCCTATTAT
TTTGAAATTACATATTTTTGAAAGCTTTTTAAAAGATACTATTGCCTGGGAAATTCTATTCAAT
AAAATGCTAATGAGAAAAGATAGTGTGTACTTTCTTCCA

hide sequence

RefSeq Acc Id:

XM_006510857 ⟹ XP_006510920

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	92,157,713 - 92,179,784 (+)	NCBI
GRCm38	9	92,275,660 - 92,297,731 (+)	NCBI

Sequence:

show sequence

GGTCAGAGTAAAGGGAATGCCAGTAAGTGTTCCTTTGGCGTTCCAGAACTGTGCACAGACCAGA
TATTCATTTCTACTGAGAGCCTCTGCCAGGAGCAGCTAACAATTCTCAAAGGACTTAGAACTCA
GACAGGGTTTCAATTTGGTTGCGTATCTTTCCAGTCAGGAAAAGGAAATCTAAAGACTCAGGAA
ACAAAACCTAAACTGCCTCAAAGTCCAGGTGCTTTTTCTCCCTGACTTTAGTCTAGTGGAGTAG
TGCAGCACCTATGCCTTTCTGAGAGGAGTCTGGAGAGCTGAGTCGCTGCTGGTGCTAGGATTCT
AGGAATTCGCCTCACTTGGAGCTGCATGAGAAAGTACCATCCATCACCACACACAGGCTTGCAA
ATGGAGGCTCCTCGCTCAGGAACATACTTGCCAGCTGGGTATGCCCCTCAGTATCCTCCAGCAG
CAGTCCAAGGACCTCCAGAGCATACTGGACGCCCCACATTCCAGACTAACTACCAAGTTCCCCA
GTCTGGTTATCCAGGACCTCAGGCTAGCTACACAGTCTCAACATCTGGACATGAAGGTTATGCT
GCTACACGGCTTCCTATTCAAAATAATCAGACTATAGTCCTTGCAAACACTCAGTGGATGCCAG
CACCACCACCTATTCTGAACTGCCCACCTGGGCTAGAATACTTAAATCAGATAGATCAGCTTCT
GATTCATCAGCAAGTTGAACTTCTAGAAGTCTTAACAGGCTTTGAAACAAATAACAAATTTGAA
ATCAAGAACAGCCTCGGGCAGATGGTTTATGTTGCAGTGGAAGATACTGACTGCTGTACTCGAA
ATTGCTGTGAAGCGTCTAGACCTTTCACTTTAAGAATCCTGGATCATCTGGGCCAAGAAGTCAT
GACTCTGGAGAGACCTCTGAAATGCAGTAGCTGCTGCTTCCCTTGCTGCCTCCAGGAGATAGAA
ATCCAGGCTCCTCCAGGGGTGCCAATAGGTTATGTGACTCAGACCTGGCACCCATGTCTGCCAA
AGCTCACTCTTCAGAACGACAAGAGGGAGAATGTTCTAAAAGTAGTTGGTCCATGTGTTGCATG
CACCTGCTGTTCAGATATTGACTTTGAGATCAAGTCTCTTGATGAAGTGACTAGAATTGGTAAG
ATCACCAAGCAGTGGTCTGGTTGTGTGAAAGAGGCCTTCACGGATTCGGATAACTTTGGGATCC
AATTCCCGCTAGACCTGGAGGTGAAGATGAAAGCTGTGACGCTTGGTGCTTGCTTCCTCATAGA
TTACATGTTTTTTGAAGGCTGTGAGTAGGAACAGAAATCCGACCTGCAGTAGGAATCAATGAAA
GAGGACAGAGAAGATCTGAAGTCTACACAAGGAGATCATATGATTGAGAGACCTGGGGCTTTTT
GATTTCTTCATTGAAATTTCTCAGAATCAAGCTGTTATACATGAAGCATAGTATGTAACATTTT
GGTTTTCAAATGGTAGTTTATCTTTTACATTATTGGAATAGACCTGGATAATTATCTTTATACA
CTTCTAAAAATATGCACCAAATTCAAGTTAAAAAAAAAAGACGAAGAGAAGTGTATGTTTTAAA
ATAAAACATTTTATGGAAAAGTAAGTTAAATCATAATCTTTGATTTATTTTTCATCTTTTGTTC
AATTTAAACCTTGTTAGTGCTGATTTTATTATAAAATTGTACTTTACTATCAAACCTAGTTAGT
TTATTTCTTACAGAAATCCTCCTATTATTTTGAAATTACATATTTTTGAAAGCTTTTTAAAAGA
TACTATTGCCTGGGAAATTCTATTCAATAAAATGCTAATGAGAAAA

hide sequence

RefSeq Acc Id:

XM_011242676 ⟹ XP_011240978

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	92,171,716 - 92,179,784 (+)	NCBI
GRCm38	9	92,289,663 - 92,297,731 (+)	NCBI

Sequence:

show sequence

ATAGATCAGCTTCTGATTCATCAGCAAGTTGAACTTCTAGAAGCACTGGATGACCATACTCAGG
AAAGCCCCCTTGTGACAAGAGTGCATGGAGTTGAAGACACAGCTTGCTCTCTTTCAAGGTCTCA
CATATGGACTTCATTCCTTCTTACCTGAATGTTCTTCCTCCTTTCCCACTGCCATTTCCTGAGT
CCAGATCATCTCCGCACTGCCTGTCTCTCCTTTTCTGCTGTTCCACTCTTAACAGGCTTTGAAA
CAAATAACAAATTTGAAATCAAGAACAGCCTCGGGCAGATGGTTTATGTTGCAGTGGAAGATAC
TGACTGCTGTACTCGAAATTGCTGTGAAGCGTCTAGACCTTTCACTTTAAGAATCCTGGATCAT
CTGGGCCAAGAAGTCATGACTCTGGAGAGACCTCTGAAATGCAGTAGCTGCTGCTTCCCTTGCT
GCCTCCAGGAGATAGAAATCCAGGCTCCTCCAGGGGTGCCAATAGGTTATGTGACTCAGACCTG
GCACCCATGTCTGCCAAAGCTCACTCTTCAGAACGACAAGAGGGAGAATGTTCTAAAAGTAGTT
GGTCCATGTGTTGCATGCACCTGCTGTTCAGATATTGACTTTGAGATCAAGTCTCTTGATGAAG
TGACTAGAATTGGTAAGATCACCAAGCAGTGGTCTGGTTGTGTGAAAGAGGCCTTCACGGATTC
GGATAACTTTGGGATCCAATTCCCGCTAGACCTGGAGGTGAAGATGAAAGCTGTGACGCTTGGT
GCTTGCTTCCTCATAGATTACATGTTTTTTGAAGGCTGTGAGTAGGAACAGAAATCCGACCTGC
AGTAGGAATCAATGAAAGAGGACAGAGAAGATCTGAAGTCTACACAAGGAGATCATATGATTGA
GAGACCTGGGGCTTTTTGATTTCTTCATTGAAATTTCTCAGAATCAAGCTGTTATACATGAAGC
ATAGTATGTAACATTTTGGTTTTCAAATGGTAGTTTATCTTTTACATTATTGGAATAGACCTGG
ATAATTATCTTTATACACTTCTAAAAATATGCACCAAATTCAAGTTAAAAAAAAAAGACGAAGA
GAAGTGTATGTTTTAAAATAAAACATTTTATGGAAAAGTAAGTTAAATCATAATCTTTGATTTA
TTTTTCATCTTTTGTTCAATTTAAACCTTGTTAGTGCTGATTTTATTATAAAATTGTACTTTAC
TATCAAACCTAGTTAGTTTATTTCTTACAGAAATCCTCCTATTATTTTGAAATTACATATTTTT
GAAAGCTTTTTAAAAGATACTATTGCCTGGGAAATTCTATTCAATAAAATGCTAATGAGAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001182013	(Get FASTA)	NCBI Sequence Viewer
	NP_032906	(Get FASTA)	NCBI Sequence Viewer
	XP_006510920	(Get FASTA)	NCBI Sequence Viewer
	XP_011240978	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC40053	(Get FASTA)	NCBI Sequence Viewer
	AAH02012	(Get FASTA)	NCBI Sequence Viewer
	AAH11299	(Get FASTA)	NCBI Sequence Viewer
	BAB22079	(Get FASTA)	NCBI Sequence Viewer
	EDL20918	(Get FASTA)	NCBI Sequence Viewer
	Q9DCW2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_032906 ⟸ NM_008880

- UniProtKB:

Q9DCW2 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MEAPRSGTYLPAGYAPQYPPAAVQGPPEHTGRPTFQTNYQVPQSGYPGPQASYTVSTSGHEGYA
ATRLPIQNNQTIVLANTQWMPAPPPILNCPPGLEYLNQIDQLLIHQQVELLEVLTGFETNNKFE
IKNSLGQMVYVAVEDTDCCTRNCCEASRPFTLRILDHLGQEVMTLERPLKCSSCCFPCCLQEIE
IQAPPGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLDEVTRIGK
ITKQWSGCVKEAFTDSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFEGCE

hide sequence

RefSeq Acc Id:

NP_001182013 ⟸ NM_001195084

- UniProtKB:

Q9DCW2 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MEAPRSGTYLPAGYAPQYPPAAVQGPPEHTGRPTFQTNYQVPQSGYPGPQASYTVSTSGHEGYA
ATRLPIQNNQTIVLANTQWMPAPPPILNCPPGLEYLNQIDQLLIHQQVELLEVLTGFETNNKFE
IKNSLGQMVYVAVEDTDCCTRNCCEASRPFTLRILDHLGQEVMTLERPLKCSSCCFPCCLQEIE
IQAPPGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLDEVTRIGK
ITKQWSGCVKEAFTDSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFEGCE

hide sequence

RefSeq Acc Id:

XP_006510920 ⟸ XM_006510857

- Peptide Label:

isoform X1

- Sequence:

show sequence

MRKYHPSPHTGLQMEAPRSGTYLPAGYAPQYPPAAVQGPPEHTGRPTFQTNYQVPQSGYPGPQA
SYTVSTSGHEGYAATRLPIQNNQTIVLANTQWMPAPPPILNCPPGLEYLNQIDQLLIHQQVELL
EVLTGFETNNKFEIKNSLGQMVYVAVEDTDCCTRNCCEASRPFTLRILDHLGQEVMTLERPLKC
SSCCFPCCLQEIEIQAPPGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDF
EIKSLDEVTRIGKITKQWSGCVKEAFTDSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFEGCE

hide sequence

RefSeq Acc Id:

XP_011240978 ⟸ XM_011242676

- Peptide Label:

isoform X2

- Sequence:

show sequence

MFFLLSHCHFLSPDHLRTACLSFSAVPLLTGFETNNKFEIKNSLGQMVYVAVEDTDCCTRNCCE
ASRPFTLRILDHLGQEVMTLERPLKCSSCCFPCCLQEIEIQAPPGVPIGYVTQTWHPCLPKLTL
QNDKRENVLKVVGPCVACTCCSDIDFEIKSLDEVTRIGKITKQWSGCVKEAFTDSDNFGIQFPL
DLEVKMKAVTLGACFLIDYMFFEGCE

hide sequence

RefSeq Acc Id:

ENSMUSP00000108667 ⟸ ENSMUST00000113044

RefSeq Acc Id:

ENSMUSP00000034932 ⟸ ENSMUST00000034932

RefSeq Acc Id:

ENSMUSP00000119104 ⟸ ENSMUST00000126911

RefSeq Acc Id:

ENSMUSP00000136481 ⟸ ENSMUST00000180154

Promoters

RGD ID:

6844962

Promoter ID:

MM_KWN:58370

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Kidney, Liver, Lung

Transcripts:

OTTMUST00000055273, OTTMUST00000055274

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	9	92,169,451 - 92,170,777 (+)	MPROMDB

RGD ID:

6844963

Promoter ID:

MM_KWN:58372

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney

Transcripts:

OTTMUST00000055275

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	9	92,185,136 - 92,185,636 (+)	MPROMDB

RGD ID:

8670440

Promoter ID:

EPDNEW_M13251

Type:

initiation region

Name:

Plscr2_2

Description:

Mus musculus phospholipid scramblase 2 , transcript variant B,mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M13252

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	92,275,681 - 92,275,741	EPDNEW

RGD ID:

8670442

Promoter ID:

EPDNEW_M13252

Type:

initiation region

Name:

Plscr2_1

Description:

Mus musculus phospholipid scramblase 2 , transcript variant B,mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M13251

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	92,275,882 - 92,275,942	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1270860	AgrOrtholog
Ensembl Genes	ENSMUSG00000032372	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000034932	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000108667	UniProtKB/TrEMBL
	ENSMUSP00000119104	UniProtKB/TrEMBL
	ENSMUSP00000136481	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000034932	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000113044	UniProtKB/TrEMBL
	ENSMUST00000126911	UniProtKB/TrEMBL
	ENSMUST00000180154	UniProtKB/Swiss-Prot
InterPro	Scramblase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:18828	UniProtKB/Swiss-Prot
MGD	MGI:1270860	ENTREZGENE
NCBI Gene	18828	ENTREZGENE
PANTHER	PTHR23248	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Scramblase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Plscr2	PhenoGen
UniGene	Mm.10306	ENTREZGENE
UniProt	D3Z2S8_MOUSE	UniProtKB/TrEMBL
	D3Z7J3_MOUSE	UniProtKB/TrEMBL
	PLS2_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	O70233	UniProtKB/Swiss-Prot
	Q921P6	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD