Gene: Zmynd10 (zinc finger, MYND domain containing 10) Mus musculus
Analyze
Symbol:
Zmynd10
Name:
zinc finger, MYND domain containing 10
Description:
ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN inner dynein arm assembly; outer dynein arm assembly; positive regulation of motile cilium assembly; ASSOCIATED WITH abnormal brain ependyma motile cilium morphology; abnormal brain ependyma motile cilium physiology; abnormal head morphology; ASSOCIATED WITH Ciliary Motility Disorders (ortholog); Kartagener syndrome (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN apical plasma membrane; centriolar satellite (ortholog); cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; arsenite(3-)
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
Blu; zinc finger MYND domain-containing protein 10
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ZMYND10 (zinc finger MYND-type containing 10) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):
Zmynd10 (zinc finger, MYND-type containing 10) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Zmynd10 (zinc finger MYND-type containing 10) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ZMYND10 (zinc finger MYND-type containing 10) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ZMYND10 (zinc finger MYND-type containing 10) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Zmynd10 (zinc finger MYND-type containing 10) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ZMYND10 (zinc finger MYND-type containing 10) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Zmynd10 (zinc finger, MYND-type containing 10)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
ZMYND10 (zinc finger MYND-type containing 10)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
zmynd10 (zinc finger, MYND-type containing 10)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, ZFIN)
Drosophila melanogaster (fruit fly):
Zmynd10
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 9 107,546,872 - 107,551,321 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 9 107,449,641 - 107,453,650 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 9 107,405,411 - 107,409,420 (+) NCBI mm8 Celera 9 107,156,073 - 107,160,082 (+) NCBI Celera Cytogenetic Map 9 F1 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
Ciliary Motility Disorders ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia ClinVar PMID:28492532 Ciliary Motility Disorders ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia ClinVar PMID:25741868 , PMID:28492532 Ciliary Motility Disorders ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia ClinVar PMID:23891469 , PMID:28492532 Ciliary Motility Disorders ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia ClinVar PMID:23891471 , PMID:28492532 Ciliary Motility Disorders ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia ClinVar PMID:23891469 more ... Kartagener syndrome ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:23891469 more ... Kartagener syndrome ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:23891471 , PMID:28492532 primary ciliary dyskinesia ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:28492532 primary ciliary dyskinesia ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:25741868 , PMID:28492532 primary ciliary dyskinesia ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:23891469 , PMID:28492532 primary ciliary dyskinesia ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:23891471 , PMID:28492532 primary ciliary dyskinesia ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Primary ciliary dyskinesia ClinVar PMID:23891469 more ... primary ciliary dyskinesia 22 ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia, primary, 22 ClinVar PMID:25741868 , PMID:28492532 primary ciliary dyskinesia 22 ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia, primary, 22 ClinVar PMID:23891469 primary ciliary dyskinesia 22 ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia, primary, 22 ClinVar PMID:23891471 , PMID:28492532 primary ciliary dyskinesia 22 ISO RGD:1351816 8554872 ClinVar Annotator: match by term: Ciliary dyskinesia, primary, 22 ClinVar PMID:23891469 more ...
Imported Annotations - MGI
primary ciliary dyskinesia 22 IEA 13592920 OMIM:615444 MouseDO
Imported Annotations - OMIM
primary ciliary dyskinesia 22 ISO RGD:1351816 7240710 OMIM
Gene-Chemical Interaction Annotations
17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZMYND10 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZMYND10 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ZMYND10 mRNA CTD PMID:26377647 acrylamide increases expression ISO RGD:1303250 6480464 Acrylamide results in increased expression of ZMYND10 mRNA CTD PMID:28959563 aflatoxin B1 increases methylation ISO RGD:1351816 6480464 Aflatoxin B1 results in increased methylation of ZMYND10 gene CTD PMID:28458013 amiodarone increases expression ISO RGD:1351816 6480464 Amiodarone results in increased expression of ZMYND10 mRNA CTD PMID:19774075 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of ZMYND10 mRNA CTD PMID:18929588 bisphenol A affects expression ISO RGD:1351816 6480464 bisphenol A affects the expression of ZMYND10 mRNA CTD PMID:20170705 bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of ZMYND10 promoter CTD PMID:27312807 bisphenol A affects expression ISO RGD:1303250 6480464 bisphenol A affects the expression of ZMYND10 mRNA CTD PMID:25181051 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of ZMYND10 mRNA, Nanotubes, Carbon results in decreased expression of ZMYND10 mRNA CTD PMID:25554681 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of ZMYND10 mRNA CTD PMID:23125180 diethylstilbestrol decreases expression ISO RGD:1351816 6480464 Diethylstilbestrol results in decreased expression of ZMYND10 mRNA CTD PMID:19371625 entinostat increases expression ISO RGD:1351816 6480464 entinostat results in increased expression of ZMYND10 mRNA CTD PMID:27188386 furan decreases expression ISO RGD:1303250 6480464 furan results in decreased expression of ZMYND10 mRNA CTD PMID:25539665 glycidol increases expression ISO RGD:1303250 6480464 glycidol results in increased expression of ZMYND10 mRNA CTD PMID:24395379 lead diacetate affects expression ISO RGD:1303250 6480464 lead acetate affects the expression of ZMYND10 mRNA CTD PMID:21864555 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ZMYND10 mRNA CTD PMID:23811191 sodium arsenite increases methylation ISO RGD:1351816 6480464 sodium arsenite results in increased methylation of ZMYND10 gene CTD PMID:24570342 tetraphene increases expression EXP 6480464 benz(a)anthracene results in increased expression of ZMYND10 mRNA CTD PMID:26377693 titanium dioxide affects expression EXP 6480464 titanium dioxide affects the expression of ZMYND10 mRNA CTD PMID:23557971 trichostatin A multiple interactions ISO RGD:1351816 6480464 [decitabine co-treated with trichostatin A] affects the expression of ZMYND10 mRNA CTD PMID:18819746 valproic acid increases methylation ISO RGD:1351816 6480464 Valproic Acid results in increased methylation of ZMYND10 gene CTD PMID:29154799 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of ZMYND10 mRNA CTD PMID:18930951 zearalenone decreases expression ISO RGD:1351816 6480464 Zearalenone results in decreased expression of ZMYND10 mRNA CTD PMID:19371625
Gene Ontology Annotations
Biological Process inner dynein arm assembly ISO UniProtKB:O75800 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 inner dynein arm assembly IMP 2290270 (MGI:MGI:6154799, PMID:29601588) UniProtKB MGI:MGI:6154799 , PMID:29601588 inner dynein arm assembly IBA PANTHER:PTN000326508 , UniProtKB:O75800 2290270 (PMID:21873635) GO_Central PMID:21873635 motile cilium assembly ISO UniProtKB:O75800 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 motile cilium assembly IBA FB:FBgn0266709 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 outer dynein arm assembly ISO UniProtKB:O75800 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 outer dynein arm assembly IMP 2290270 (MGI:MGI:6154799, PMID:29601588) UniProtKB MGI:MGI:6154799 , PMID:29601588 outer dynein arm assembly IBA PANTHER:PTN000326508 , UniProtKB:O75800 2290270 (PMID:21873635) GO_Central PMID:21873635 positive regulation of motile cilium assembly IMP 2290270 (MGI:MGI:6154799, PMID:29601588) UniProtKB MGI:MGI:6154799 , PMID:29601588 Cellular Component apical plasma membrane IDA 2290270 (MGI:MGI:6154799, PMID:29601588) UniProtKB MGI:MGI:6154799 , PMID:29601588 centriolar satellite ISO RGD:1303250 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 centriolar satellite IBA PANTHER:PTN000326508 , RGD:1303250 2290270 (PMID:21873635) GO_Central PMID:21873635 cytoplasm ISO UniProtKB:O75800 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 cytoplasm IBA FB:FBgn0266709 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 cytoskeleton IEA UniProtKB-KW:KW-0206 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 membrane IEA UniProtKB-KW:KW-0472 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 plasma membrane IEA UniProtKB-KW:KW-1003 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 Molecular Function metal ion binding IEA UniProtKB-KW:KW-0479 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 molecular_function ND 2290270 MGI GO_REF:0000015, MGI:MGI:2156816
Phenotype Annotations
4141833 W10q13_m weight 10 weeks QTL 13 (mouse) Not determined 63332429 120362868 Mouse 12904947 Tammq7_m tibialis anterior muscle mass QTL 7 (mouse) 9 91683173 124595110 Mouse 13463478 Mchq18_m mean corpuscular hemoglobin QTL 18 (mouse) 9 91641084 124595110 Mouse 13207569 Tcq13_m total cholesterol QTL 13 (mouse) 9 59990000 109260000 Mouse 1302001 Bdln5_m body length 5 (mouse) Not determined 9 93762590 124595110 Mouse 13463474 Hbbcq5_m hemoglobin concentration QTL 5 (mouse) 9 91641084 124595110 Mouse 10054492 El7_m epilepsy 7 (mouse) Not determined 9 75775364 114474379 Mouse 12910772 Lvic6_m liver iron content 6 (mouse) 9 91413879 124595110 Mouse 1357461 Idd2_m insulin dependent diabetes susceptibility 2 (mouse) Not determined 9 82910333 116910428 Mouse 11081166 Psl5_m promotion susceptibility QTL 5 (mouse) 9 94981301 112872929 Mouse 1357627 Tgq2_m triglyceride QTL 2 (mouse) Not determined 9 102000187 124595110 Mouse 1302103 Dob2_m dietary obesity 2 (mouse) Not determined 9 86239845 120289624 Mouse 1301192 Skts6_m skin tumor susceptibility 6 (mouse) Not determined 9 78640645 112640755 Mouse 13463477 Rbc9_m red blood cell count 9 (mouse) 9 91641084 124595110 Mouse 10412290 Pvacm1l_m plasma vascular cell adhesion molecule 1 levels (mouse) Not determined 9 103289445 124595110 Mouse 10766454 Char10_m P. chabaudi malaria resistance QTL 10 (mouse) 9 82910333 116910428 Mouse 1357635 Splq4_m spleen weight QTL 4 (mouse) Not determined 9 63332429 120362868 Mouse 1357657 Pymr_m Plasmodium yoelli malaria resistance (mouse) Not determined 9 89977005 118938021 Mouse 10412242 Alpq8_m alcohol preference QTL 8 (mouse) Not determined 9 89284925 123284925 Mouse 1300549 Bbaa17_m B. burgdorferi-associated arthritis 17 (mouse) Not determined 9 86230401 120230530 Mouse 12904961 Gmmq7_m gastrocnemius muscle mass QTL 7 (mouse) 9 91683173 124595110 Mouse 1558767 Skmw11_m skeletal muscle weight 11 (mouse) Not determined 9 91641084 124595110 Mouse 13463480 Mchcq2_m mean corpuscular hemoglobin concentration QTL 2 (mouse) 9 91641084 124595110 Mouse 12910773 Splic3_m spleen iron content 3 (mouse) 9 91413879 124595110 Mouse 12879896 Berr3_m berghei resistance locus 3 (mouse) 9 103289445 124595110 Mouse 11537364 Cnes5_m C. neoformans susceptibility locus 5 (mouse) 9 96917590 124595110 Mouse 14746992 Manh67_m mandible shape 67 (mouse) 9 94036768 124595110 Mouse 10401247 Bglu14_m blood glucose level 14 (mouse) Not determined 9 79397810 113397888 Mouse 4141545 Tailaq2_m tail length adjusted QTL 2 (mouse) Not determined 63332429 120362868 Mouse 1300884 Sluc11_m susceptibility to lung cancer 11 (mouse) Not determined 9 82910333 116910428 Mouse 1302065 El1_m epilepsy 1 (mouse) Not determined 9 75775364 114474379 Mouse 1301732 Char1_m P. chabaudi malaria resistance QTL 1 (mouse) Not determined 9 81798268 115798392 Mouse 1301789 Pbwg4_m postnatal body weight growth 4 (mouse) Not determined 9 103289445 124595110 Mouse 11251716 Siim2_m stress induced immobility 2 (mouse) 9 86748483 120748483 Mouse 12880422 V25Dq6_m vitamin D inactive form serum level QTL 6 (mouse) 9 87800000 121800000 Mouse 1301407 Rapop2_m radiation-induced apoptosis 2 (mouse) Not determined 9 76535936 110536130 Mouse 1301725 Lifespan1_m life span 1 (mouse) Not determined 9 74368177 108368325 Mouse 1357648 Obq18_m obesity QTL 18 (mouse) Not determined 9 102000187 124595110 Mouse 1301487 Nociq1_m nociceptive sensitivity inflammatory QTL 1 (mouse) Not determined 9 84528818 118528921 Mouse 1301297 Lcho1_m liver cholesterol 1 (mouse) Not determined 9 101060861 124595110 Mouse 10412180 Msam3_m muscle, skeletal, activity measure 3 (mouse) Not determined 9 85897510 108641186 Mouse 1301649 Psl1_m promotion susceptibility QTL 1 (mouse) Not determined 9 89412277 123412396 Mouse 12910770 Splic1_m spleen iron content 1 (mouse) 9 91413879 124595110 Mouse 1301484 Bwq6_m body weight (mouse) Not determined 9 93762590 124595110 Mouse 13463475 Hctq7_m hematocrit QTL 7 (mouse) 9 91641084 124595110 Mouse 12904937 Edlmmq9_m extensor digitorum longus muscle mass QTL 9 (mouse) 9 91683173 124595110 Mouse
Predicted Target Of
Count of predictions: 178 Count of miRNA genes: 153 Interacting mature miRNAs: 172 Transcripts: ENSMUST00000010188 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
Gene-Chemical Interaction Annotations
