Zmynd10 (zinc finger, MYND domain containing 10) - Rat Genome Database
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Gene: Zmynd10 (zinc finger, MYND domain containing 10) Mus musculus
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Symbol: Zmynd10
Name: zinc finger, MYND domain containing 10
RGD ID: 1551456
MGI Page MGI
Description: Exhibits molecular adaptor activity and protein folding chaperone. Involved in several processes, including cilium assembly; positive regulation of motile cilium assembly; and sperm motility. Localizes to apical plasma membrane and cytoplasm. Is expressed in bronchiole epithelium; lung; lung epithelium; nasal cavity epithelium; and nasal cavity respiratory epithelium. Used to study primary ciliary dyskinesia 22. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 22. Orthologous to human ZMYND10 (zinc finger MYND-type containing 10); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bl; Blu; zinc finger MYND domain-containing protein 10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,424,067 - 107,428,520 (+)NCBIGRCm39mm39
GRCm389107,546,872 - 107,551,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,547,298 - 107,551,319 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,449,641 - 107,453,650 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,405,411 - 107,409,420 (+)NCBImm8
Celera9107,156,073 - 107,160,082 (+)NCBICelera
Cytogenetic Map9F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12629521   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17971504   PMID:21677750  
PMID:21873635   PMID:23891471   PMID:27914912   PMID:29329290   PMID:29601588   PMID:29916806   PMID:32325033  


Genomics

Comparative Map Data
Zmynd10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,424,067 - 107,428,520 (+)NCBIGRCm39mm39
GRCm389107,546,872 - 107,551,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,547,298 - 107,551,319 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,449,641 - 107,453,650 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,405,411 - 107,409,420 (+)NCBImm8
Celera9107,156,073 - 107,160,082 (+)NCBICelera
Cytogenetic Map9F1NCBI
ZMYND10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl350,341,110 - 50,345,732 (-)EnsemblGRCh38hg38GRCh38
GRCh38350,341,110 - 50,345,732 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37350,378,537 - 50,383,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,353,541 - 50,358,160 (-)NCBINCBI36hg18NCBI36
Build 34350,353,540 - 50,358,160NCBI
Celera350,351,371 - 50,355,987 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef350,434,168 - 50,438,757 (-)NCBIHuRef
CHM1_1350,330,797 - 50,335,433 (-)NCBICHM1_1
Zmynd10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08116,302,513 - 116,306,871 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,302,513 - 116,306,870 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08115,658,773 - 115,663,131 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,794,227 - 112,798,585 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18112,813,681 - 112,818,039 (+)NCBI
Celera8107,526,809 - 107,531,167 (+)NCBICelera
Cytogenetic Map8q32NCBI
Zmynd10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555322,142,229 - 2,147,621 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555322,142,114 - 2,147,622 (-)NCBIChiLan1.0ChiLan1.0
ZMYND10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1351,502,548 - 51,508,288 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,502,548 - 51,508,288 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0350,267,218 - 50,273,009 (-)NCBIMhudiblu_PPA_v0panPan3
ZMYND10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2039,010,225 - 39,014,356 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12039,009,838 - 39,014,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Zmynd10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365291,866,258 - 1,870,162 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZMYND10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,825,369 - 32,830,049 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,825,398 - 32,830,037 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21336,003,901 - 36,008,288 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZMYND10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,728,792 - 11,734,252 (-)NCBI
ChlSab1.1 Ensembl2211,728,795 - 11,733,726 (-)Ensembl
Zmynd10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247304,190,706 - 4,195,003 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:178
Count of miRNA genes:153
Interacting mature miRNAs:172
Transcripts:ENSMUST00000010188
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000010188   ⟹   ENSMUSP00000010188
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,547,298 - 107,551,319 (+)Ensembl
RefSeq Acc Id: ENSMUST00000192445
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,550,489 - 107,551,219 (+)Ensembl
RefSeq Acc Id: ENSMUST00000193303   ⟹   ENSMUSP00000141420
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,547,454 - 107,551,319 (+)Ensembl
RefSeq Acc Id: ENSMUST00000195158
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,549,163 - 107,550,211 (+)Ensembl
RefSeq Acc Id: ENSMUST00000195627
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,547,304 - 107,547,869 (+)Ensembl
RefSeq Acc Id: NM_001379079   ⟹   NP_001366008
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,424,503 - 107,428,520 (+)NCBI
GRCm389107,547,304 - 107,551,321 (+)NCBI
RefSeq Acc Id: NM_001379080   ⟹   NP_001366009
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,424,503 - 107,428,520 (+)NCBI
GRCm389107,547,304 - 107,551,321 (+)NCBI
RefSeq Acc Id: NM_053253   ⟹   NP_444483
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,424,503 - 107,428,520 (+)NCBI
GRCm389107,547,304 - 107,551,321 (+)NCBI
MGSCv379107,449,641 - 107,453,650 (+)RGD
Celera9107,156,073 - 107,160,082 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_166465
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,424,503 - 107,428,520 (+)NCBI
GRCm389107,547,304 - 107,551,321 (+)NCBI
RefSeq Acc Id: XM_006511630   ⟹   XP_006511693
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,424,067 - 107,428,520 (+)NCBI
GRCm389107,546,872 - 107,551,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313107   ⟹   XP_017168596
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,424,071 - 107,428,520 (+)NCBI
GRCm389107,546,876 - 107,551,321 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_444483   ⟸   NM_053253
- Peptide Label: isoform 1
- UniProtKB: Q99ML0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006511693   ⟸   XM_006511630
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017168596   ⟸   XM_017313107
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001366008   ⟸   NM_001379079
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001366009   ⟸   NM_001379080
- Peptide Label: isoform 3
RefSeq Acc Id: ENSMUSP00000141420   ⟸   ENSMUST00000193303
RefSeq Acc Id: ENSMUSP00000010188   ⟸   ENSMUST00000010188

Promoters
RGD ID:6845372
Promoter ID:MM_KWN:58718
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:ENSMUST00000010188,   UC009RLP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369107,449,359 - 107,449,859 (+)MPROMDB
RGD ID:8670792
Promoter ID:EPDNEW_M13426
Type:initiation region
Name:Zmynd10_1
Description:Mus musculus zinc finger, MYND domain containing 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389107,547,304 - 107,547,364EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2387863 AgrOrtholog
Ensembl Genes ENSMUSG00000010044 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000010188 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141420 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000010188 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000193303 UniProtKB/TrEMBL
InterPro UCP037948_Znf-MYND UniProtKB/Swiss-Prot
  Znf_MYND UniProtKB/Swiss-Prot
KEGG Report mmu:114602 UniProtKB/Swiss-Prot
MGD MGI:2387863 ENTREZGENE
NCBI Gene 114602 ENTREZGENE
Pfam zf-MYND UniProtKB/Swiss-Prot
PhenoGen Zmynd10 PhenoGen
PIRSF UCP037948_Znf_MYND10 UniProtKB/Swiss-Prot
PROSITE ZF_MYND_1 UniProtKB/Swiss-Prot
  ZF_MYND_2 UniProtKB/Swiss-Prot
UniProt A0A0A6YW68_MOUSE UniProtKB/TrEMBL
  Q99ML0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3V1P0 UniProtKB/Swiss-Prot
  Q80W73 UniProtKB/Swiss-Prot