Or1i2 (olfactory receptor family 1 subfamily I member 1) - Rat Genome Database

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Gene: Or1i2 (olfactory receptor family 1 subfamily I member 1) Mus musculus
Analyze
Symbol: Or1i2
Name: olfactory receptor family 1 subfamily I member 1
RGD ID: 1551406
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in olfactory epithelium. Orthologous to human OR1I1 (olfactory receptor family 1 subfamily I member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2QGN0-3196801-3197742; MOR128; MOR128-3; MOR128-4; olfactory receptor 1357; olfactory receptor MOR128-3; Olfr1357
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,447,503 - 78,453,908 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,446,837 - 78,453,908 (-)EnsemblGRCm39 Ensembl
GRCm381078,611,669 - 78,618,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,611,003 - 78,618,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,074,414 - 78,080,819 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,014,827 - 78,015,768 (-)NCBIMGSCv36mm8
Celera1079,633,878 - 79,640,283 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:15081110   PMID:16602821   PMID:21267068   PMID:21873635   PMID:25437545   PMID:32295537  


Genomics

Comparative Map Data
Or1i2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,447,503 - 78,453,908 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,446,837 - 78,453,908 (-)EnsemblGRCm39 Ensembl
GRCm381078,611,669 - 78,618,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,611,003 - 78,618,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,074,414 - 78,080,819 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,014,827 - 78,015,768 (-)NCBIMGSCv36mm8
Celera1079,633,878 - 79,640,283 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
OR1I1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,082,211 - 15,092,970 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,082,211 - 15,092,970 (+)EnsemblGRCh38hg38GRCh38
GRCh371915,193,022 - 15,203,781 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,058,877 - 15,059,944 (+)NCBINCBI36Build 36hg18NCBI36
Build 341915,058,876 - 15,059,944NCBI
Celera1915,093,586 - 15,094,653 (+)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,765,566 - 14,766,633 (+)NCBIHuRef
CHM1_11915,197,371 - 15,198,438 (+)NCBICHM1_1
T2T-CHM13v2.01915,207,150 - 15,217,911 (+)NCBIT2T-CHM13v2.0
Or1i2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,636,515 - 11,637,456 (+)NCBIGRCr8
mRatBN7.2710,985,938 - 10,986,879 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,980,344 - 10,987,036 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,806,473 - 13,807,414 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,683,865 - 15,684,806 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,561,762 - 13,562,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,996,966 - 13,997,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,996,966 - 13,997,907 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,153,449 - 14,154,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,543,995 - 12,544,936 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,543,994 - 12,544,936 (+)NCBI
Celera79,103,332 - 9,104,273 (+)NCBICelera
Cytogenetic Map7q11NCBI
LOC102012872
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554958,171,204 - 8,172,145 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554958,171,204 - 8,172,145 (-)NCBIChiLan1.0ChiLan1.0
LOC134729652
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,998,913 - 19,999,953 (+)NCBINHGRI_mPanPan1-v2
OR1I1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,037,917 - 47,038,873 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,037,917 - 47,146,610 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,888,653 - 46,889,609 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,530,991 - 47,531,947 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12046,762,423 - 46,763,379 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02047,181,614 - 47,182,570 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,452,759 - 47,453,715 (-)NCBIUU_Cfam_GSD_1.0
LOC101977308
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,818,354 - 205,819,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,367,493 - 5,368,434 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,367,493 - 5,368,693 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100523537
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,470,357 - 62,471,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,470,108 - 62,471,575 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2262,031,244 - 62,032,482 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234061
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,682,193 - 13,683,939 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,682,583 - 13,683,647 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,844,972 - 5,846,239 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101705676
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,175,915 - 2,176,856 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,175,915 - 2,177,027 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Or1i2
241 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:86
Interacting mature miRNAs:87
Transcripts:ENSMUST00000095473
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7398721682491121Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000095473   ⟹   ENSMUSP00000093127
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1078,446,837 - 78,453,908 (-)Ensembl
GRCm38.p6 Ensembl1078,611,003 - 78,618,074 (-)Ensembl
RefSeq Acc Id: ENSMUST00000203305   ⟹   ENSMUSP00000145032
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1078,446,837 - 78,453,908 (-)Ensembl
GRCm38.p6 Ensembl1078,611,003 - 78,618,074 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205085   ⟹   ENSMUSP00000145185
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1078,447,503 - 78,448,514 (-)Ensembl
GRCm38.p6 Ensembl1078,611,669 - 78,612,680 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213877   ⟹   ENSMUSP00000150167
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1078,446,837 - 78,453,908 (-)Ensembl
GRCm38.p6 Ensembl1078,611,003 - 78,618,074 (-)Ensembl
RefSeq Acc Id: NM_001011737   ⟹   NP_001011737
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391078,447,503 - 78,453,908 (-)NCBI
GRCm381078,611,669 - 78,618,074 (-)ENTREZGENE
MGSCv371078,074,414 - 78,080,819 (-)RGD
Celera1079,633,878 - 79,640,283 (-)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001011737   ⟸   NM_001011737
- UniProtKB: Q7TQU7 (UniProtKB/TrEMBL),   A0A0N4SVB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000145032   ⟸   ENSMUST00000203305
RefSeq Acc Id: ENSMUSP00000145185   ⟸   ENSMUST00000205085
RefSeq Acc Id: ENSMUSP00000093127   ⟸   ENSMUST00000095473
RefSeq Acc Id: ENSMUSP00000150167   ⟸   ENSMUST00000213877
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TQU7-F1-model_v2 AlphaFold Q7TQU7 1-313 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3031191 AgrOrtholog
Ensembl Genes ENSMUSG00000071185 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000095473 ENTREZGENE
  ENSMUST00000095473.6 UniProtKB/TrEMBL
  ENSMUST00000203305.3 UniProtKB/TrEMBL
  ENSMUST00000205085.2 UniProtKB/TrEMBL
  ENSMUST00000213877.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:257883 UniProtKB/TrEMBL
MGD MGI:3031191 ENTREZGENE
NCBI Gene 257883 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 1I1 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1i2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0N4SVB6 ENTREZGENE
  Q7TQU7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0N4SVB6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or1i2  olfactory receptor family 1 subfamily I member 1  Olfr1357  olfactory receptor 1357  Symbol and/or name change 5135510 APPROVED