Ifi47 (interferon gamma inducible protein 47) - Rat Genome Database

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Gene: Ifi47 (interferon gamma inducible protein 47) Mus musculus
Analyze
No known orthologs.
Symbol: Ifi47
Name: interferon gamma inducible protein 47
RGD ID: 1551383
MGI Page MGI
Description: Predicted to enable GTPase activity. Acts upstream of or within defense response. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in alimentary system; axial skeleton; and liver.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 47kD; 47kDa; Ifggc1; Ig; Igrd; Ii; Iigp4; Iipg4; Immunity related GTPase family D; interferon gamma inducible protein, 47 kDa; interferon-gamma-inducible GTPase Ifggc1 protein; IRG-; IRG-47; Irgd; Olfr56; OTTMUSPWKG00059382; OTTMUSWSBG00059284
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391148,967,414 - 48,987,814 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1148,967,414 - 48,987,801 (+)EnsemblGRCm39 Ensembl
GRCm381149,076,587 - 49,096,987 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1149,076,587 - 49,096,974 (+)EnsemblGRCm38mm10GRCm38
MGSCv371148,900,557 - 48,910,473 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361148,930,478 - 48,940,394 (+)NCBIMGSCv36mm8
Celera1153,649,387 - 53,659,386 (+)NCBICelera
Cytogenetic Map11B1.2NCBI
cM Map1129.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs. Gilly M and Wall R, J Immunol 1992 May 15;148(10):3275-81.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:8972906   PMID:10349636   PMID:10834841   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11457893   PMID:12466851   PMID:12477932   PMID:14681479   PMID:15908352  
PMID:16141072   PMID:16141073   PMID:17982087   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22509320  


Genomics

Variants

.
Variants in Ifi47
96 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:339
Count of miRNA genes:207
Interacting mature miRNAs:212
Transcripts:ENSMUST00000046704, ENSMUST00000109202, ENSMUST00000152914
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
13452402Hipmt3_mhippocampal morphometry trait 3 (mouse)114797732550277325Mouse

Markers in Region
Ifi47  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.2UniSTS
cM Map11 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK156785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU696734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY159742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD742161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU695226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU695230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FR734031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LT629149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LT629152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U44903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000046704   ⟹   ENSMUSP00000041975
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,977,866 - 48,987,799 (+)Ensembl
GRCm38.p6 Ensembl1149,087,039 - 49,096,972 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109202   ⟹   ENSMUSP00000104825
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,967,414 - 48,987,801 (+)Ensembl
GRCm38.p6 Ensembl1149,076,587 - 49,096,974 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152914   ⟹   ENSMUSP00000150066
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,977,527 - 48,986,263 (+)Ensembl
GRCm38.p6 Ensembl1149,086,700 - 49,095,436 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213728   ⟹   ENSMUSP00000150940
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,979,091 - 48,987,787 (+)Ensembl
GRCm38.p6 Ensembl1149,088,264 - 49,096,960 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214804   ⟹   ENSMUSP00000149108
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,977,895 - 48,986,825 (+)Ensembl
GRCm38.p6 Ensembl1149,087,068 - 49,095,998 (+)Ensembl
RefSeq Acc Id: NM_001271676   ⟹   NP_001258605
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,977,844 - 48,987,814 (+)NCBI
GRCm381149,087,017 - 49,096,987 (+)NCBI
Celera1153,638,900 - 53,659,402 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271677   ⟹   NP_001258606
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,967,414 - 48,987,814 (+)NCBI
GRCm381149,076,587 - 49,096,987 (+)NCBI
Celera1153,638,900 - 53,659,402 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008330   ⟹   NP_032356
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,977,844 - 48,987,814 (+)NCBI
GRCm381149,087,017 - 49,096,987 (+)NCBI
MGSCv371148,900,557 - 48,910,473 (+)RGD
Celera1153,638,900 - 53,659,402 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032356   ⟸   NM_008330
- UniProtKB: Q61635 (UniProtKB/TrEMBL),   A0A1G5SK64 (UniProtKB/TrEMBL),   Q3U0K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258606   ⟸   NM_001271677
- UniProtKB: Q61635 (UniProtKB/TrEMBL),   A0A1G5SK64 (UniProtKB/TrEMBL),   Q3U0K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258605   ⟸   NM_001271676
- UniProtKB: Q61635 (UniProtKB/TrEMBL),   A0A1G5SK64 (UniProtKB/TrEMBL),   Q3U0K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000041975   ⟸   ENSMUST00000046704
RefSeq Acc Id: ENSMUSP00000150066   ⟸   ENSMUST00000152914
RefSeq Acc Id: ENSMUSP00000150940   ⟸   ENSMUST00000213728
RefSeq Acc Id: ENSMUSP00000104825   ⟸   ENSMUST00000109202
RefSeq Acc Id: ENSMUSP00000149108   ⟸   ENSMUST00000214804
Protein Domains
IRG-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61635-F1-model_v2 AlphaFold Q61635 1-420 view protein structure

Promoters
RGD ID:6821096
Promoter ID:MM_KWN:7163
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000012311,   UC007IPQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361148,900,404 - 48,900,904 (+)MPROMDB
RGD ID:8674458
Promoter ID:EPDNEW_M15260
Type:initiation region
Name:Ifi47_2
Description:Mus musculus interferon gamma inducible protein 47 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15261  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381149,076,591 - 49,076,651EPDNEW
RGD ID:8674460
Promoter ID:EPDNEW_M15261
Type:initiation region
Name:Ifi47_1
Description:Mus musculus interferon gamma inducible protein 47 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15260  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381149,087,035 - 49,087,095EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99448 AgrOrtholog
Ensembl Genes ENSMUSG00000078920 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000046704 ENTREZGENE
  ENSMUST00000046704.7 UniProtKB/TrEMBL
  ENSMUST00000109202 ENTREZGENE
  ENSMUST00000109202.3 UniProtKB/TrEMBL
  ENSMUST00000152914.2 UniProtKB/TrEMBL
  ENSMUST00000213728.2 UniProtKB/TrEMBL
  ENSMUST00000214804.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro G_IRG_dom UniProtKB/TrEMBL
  Interferon-induced_GTPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report mmu:15953 UniProtKB/TrEMBL
MGD MGI:99448 ENTREZGENE
NCBI Gene 15953 ENTREZGENE
PANTHER GTP-BINDING PROTEIN UniProtKB/TrEMBL
  INTERFERON-INDUCIBLE GTPASE UniProtKB/TrEMBL
Pfam IIGP UniProtKB/TrEMBL
PhenoGen Ifi47 PhenoGen
PROSITE G_IRG UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A1G5SK64 ENTREZGENE
  A0A1L1SQM2_MOUSE UniProtKB/TrEMBL
  A0A1L1SSW0_MOUSE UniProtKB/TrEMBL
  Q3U0K0 ENTREZGENE, UniProtKB/TrEMBL
  Q61635 ENTREZGENE, UniProtKB/TrEMBL
  Q99M59_MOUSE UniProtKB/TrEMBL