Prokr1 (prokineticin receptor 1) - Rat Genome Database
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Gene: Prokr1 (prokineticin receptor 1) Mus musculus
Analyze
Symbol: Prokr1
Name: prokineticin receptor 1
RGD ID: 1551071
MGI Page MGI
Description: Is expressed in several structures, including central nervous system; eye; gut; metanephros; and reproductive system. Orthologous to human PROKR1 (prokineticin receptor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EG-VEGF; EG-VEGFR1; G protein-coupled receptor 73; G-protein coupled receptor 73; Gpr; Gpr73; Pk; PK-R1; Pkr1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,555,568 - 87,567,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,555,573 - 87,567,725 (-)Ensembl
GRCm38687,578,586 - 87,590,762 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,578,591 - 87,590,743 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,528,586 - 87,540,695 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,544,233 - 87,556,342 (-)NCBImm8
Celera689,512,929 - 89,525,034 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10760605   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11591818   PMID:11886876   PMID:12024206   PMID:12477932   PMID:12604792   PMID:12746324   PMID:15489334  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:16299550   PMID:16537498   PMID:16602821   PMID:16793879   PMID:16901473   PMID:17273929   PMID:17277741   PMID:17324478   PMID:17531315  
PMID:18421008   PMID:19030180   PMID:19386638   PMID:19667192   PMID:19877281   PMID:20023120   PMID:20299672   PMID:21267068   PMID:21273561   PMID:21873635   PMID:24152983   PMID:24194600  
PMID:24324673   PMID:26730729   PMID:26829592   PMID:27084889   PMID:27150455   PMID:27626380   PMID:29038558   PMID:30253862   PMID:31883821  


Genomics

Comparative Map Data
Prokr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,555,568 - 87,567,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,555,573 - 87,567,725 (-)Ensembl
GRCm38687,578,586 - 87,590,762 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,578,591 - 87,590,743 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,528,586 - 87,540,695 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,544,233 - 87,556,342 (-)NCBImm8
Celera689,512,929 - 89,525,034 (-)NCBICelera
Cytogenetic Map6D1NCBI
PROKR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl268,643,579 - 68,658,251 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl268,643,589 - 68,658,247 (+)EnsemblGRCh38hg38GRCh38
GRCh38268,643,579 - 68,658,251 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37268,870,711 - 68,885,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36268,726,458 - 68,736,212 (+)NCBINCBI36hg18NCBI36
Build 34268,784,604 - 68,794,359NCBI
Celera268,723,398 - 68,733,153 (+)NCBI
Cytogenetic Map2p13.3NCBI
HuRef268,609,490 - 68,619,244 (+)NCBIHuRef
CHM1_1268,802,288 - 68,812,042 (+)NCBICHM1_1
Prokr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24120,022,301 - 120,033,379 (-)NCBI
Rnor_6.0 Ensembl4119,375,778 - 119,386,590 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04119,375,790 - 119,386,551 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04183,939,201 - 183,949,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,750,651 - 121,758,116 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14121,995,131 - 122,002,597 (-)NCBI
Celera4108,992,288 - 108,999,753 (-)NCBICelera
Cytogenetic Map4q34NCBI
Prokr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542416,287,653 - 16,301,713 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542416,287,666 - 16,301,713 (-)NCBIChiLan1.0ChiLan1.0
PROKR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A69,808,032 - 69,822,410 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A69,808,033 - 69,822,404 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A68,685,129 - 68,700,372 (+)NCBIMhudiblu_PPA_v0panPan3
PROKR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1067,548,067 - 67,557,369 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11067,546,502 - 67,557,696 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Prokr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649113,004,768 - 13,015,818 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PROKR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl373,690,139 - 73,788,315 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1373,689,583 - 73,711,410 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2377,222,106 - 77,239,588 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PROKR1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11438,462,668 - 38,474,901 (-)NCBI
Prokr1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247624,667,733 - 4,679,878 (-)NCBI

Position Markers
Prokr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38687,580,039 - 87,580,101UniSTSGRCm38
MGSCv37687,530,033 - 87,530,095UniSTSGRCm37
Celera689,514,376 - 89,514,438UniSTS
Cytogenetic Map6D1UniSTS
cM Map6 UniSTS
Prokr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38687,588,718 - 87,588,820UniSTSGRCm38
Celera689,523,055 - 89,523,157UniSTS
Cytogenetic Map6D1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:742
Count of miRNA genes:506
Interacting mature miRNAs:563
Transcripts:ENSMUST00000050887
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000050887   ⟹   ENSMUSP00000059034
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,578,592 - 87,590,720 (-)Ensembl
RefSeq Acc Id: ENSMUST00000203636   ⟹   ENSMUSP00000145476
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,588,404 - 87,590,719 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204682   ⟹   ENSMUSP00000144999
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,578,591 - 87,590,743 (-)Ensembl
RefSeq Acc Id: NM_001355655   ⟹   NP_001342584
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,555,574 - 87,567,725 (-)NCBI
GRCm38687,578,592 - 87,590,743 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021381   ⟹   NP_067356
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,555,574 - 87,567,725 (-)NCBI
GRCm38687,578,592 - 87,590,743 (-)NCBI
MGSCv37687,528,586 - 87,540,695 (-)RGD
Celera689,512,929 - 89,525,034 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506432   ⟹   XP_006506495
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,555,568 - 87,567,563 (-)NCBI
GRCm38687,578,586 - 87,590,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006506433   ⟹   XP_006506496
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,555,568 - 87,567,741 (-)NCBI
GRCm38687,578,586 - 87,590,762 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_067356   ⟸   NM_021381
- UniProtKB: Q9JKL1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506495   ⟸   XM_006506432
- Peptide Label: isoform X1
- UniProtKB: Q9JKL1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506496   ⟸   XM_006506433
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001342584   ⟸   NM_001355655
RefSeq Acc Id: ENSMUSP00000145476   ⟸   ENSMUST00000203636
RefSeq Acc Id: ENSMUSP00000059034   ⟸   ENSMUST00000050887
RefSeq Acc Id: ENSMUSP00000144999   ⟸   ENSMUST00000204682

Promoters
RGD ID:6839786
Promoter ID:MM_KWN:46773
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:ENSMUST00000050887,   UC009CTP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36687,540,401 - 87,540,901 (-)MPROMDB
RGD ID:6890334
Promoter ID:EPDNEW_M8618
Type:multiple initiation site
Name:Prokr1_1
Description:Mus musculus prokineticin receptor 1 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38687,590,739 - 87,590,799EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1929676 AgrOrtholog
Ensembl Genes ENSMUSG00000049409 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000059034 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144999 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000145476 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000050887 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000203636 UniProtKB/TrEMBL
  ENSMUST00000204682 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  NPY_rcpt UniProtKB/Swiss-Prot
KEGG Report mmu:58182 UniProtKB/Swiss-Prot
MGD MGI:1929676 ENTREZGENE
NCBI Gene 58182 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Prokr1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  NRPEPTIDEYR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
UniProt A0A0N4SWD5_MOUSE UniProtKB/TrEMBL
  PKR1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3U0M4 UniProtKB/Swiss-Prot
  Q6PD11 UniProtKB/Swiss-Prot