Ptgdr (prostaglandin D receptor) - Rat Genome Database

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Gene: Ptgdr (prostaglandin D receptor) Mus musculus
Analyze
Symbol: Ptgdr
Name: prostaglandin D receptor
RGD ID: 1551031
MGI Page MGI
Description: Enables prostaglandin D receptor activity and prostaglandin J receptor activity. Acts upstream of or within several processes, including adenosine metabolic process; cellular response to prostaglandin D stimulus; and male sex determination. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR (prostaglandin D2 receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D; DP; PGD; PGD receptor; PGD2 receptor; prostaglandin D2 receptor; prostanoid DP receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm7371  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391445,088,692 - 45,096,832 (-)NCBIGRCm39mm39
GRCm39 Ensembl1445,088,692 - 45,096,832 (-)Ensembl
GRCm381444,851,235 - 44,859,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1444,851,235 - 44,859,375 (-)EnsemblGRCm38mm10GRCm38
MGSCv371445,470,910 - 45,479,050 (-)NCBIGRCm37mm9NCBIm37
MGSCv361443,773,112 - 43,781,252 (-)NCBImm8
Celera1441,045,205 - 41,053,310 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1422.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
asthma  (ISO)
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7972033   PMID:8833158   PMID:9484788   PMID:10349636   PMID:10508233   PMID:10720327   PMID:11042159   PMID:11076861   PMID:11562489   PMID:11782353   PMID:11927615   PMID:12477932  
PMID:12878180   PMID:12895603   PMID:15004188   PMID:15834430   PMID:16141072   PMID:16141073   PMID:16185683   PMID:16602821   PMID:16617107   PMID:16624958   PMID:17093043   PMID:17283205  
PMID:17442814   PMID:17573924   PMID:18258196   PMID:18938093   PMID:19060214   PMID:19966781   PMID:20566843   PMID:21166666   PMID:21267068   PMID:21356515   PMID:21460251   PMID:21703412  
PMID:21873635   PMID:21943706   PMID:22406532   PMID:22440736   PMID:22715053   PMID:23103473   PMID:23190891   PMID:23307871   PMID:23624557   PMID:24003988   PMID:24194600   PMID:24298012  
PMID:24333565   PMID:24401991   PMID:24729479   PMID:25100738   PMID:25142465   PMID:25218962   PMID:26018088   PMID:27621415   PMID:27815021   PMID:28341703   PMID:28630327   PMID:28874785  
PMID:30902371   PMID:30918168   PMID:31688905   PMID:31917615   PMID:32624353   PMID:34389796   PMID:34488442  


Genomics

Comparative Map Data
Ptgdr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391445,088,692 - 45,096,832 (-)NCBIGRCm39mm39
GRCm39 Ensembl1445,088,692 - 45,096,832 (-)Ensembl
GRCm381444,851,235 - 44,859,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1444,851,235 - 44,859,375 (-)EnsemblGRCm38mm10GRCm38
MGSCv371445,470,910 - 45,479,050 (-)NCBIGRCm37mm9NCBIm37
MGSCv361443,773,112 - 43,781,252 (-)NCBImm8
Celera1441,045,205 - 41,053,310 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1422.59NCBI
PTGDR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1452,267,698 - 52,276,724 (+)EnsemblGRCh38hg38GRCh38
GRCh381452,267,256 - 52,276,724 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371452,734,416 - 52,743,442 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361451,804,181 - 51,813,192 (+)NCBINCBI36hg18NCBI36
Build 341451,804,180 - 51,813,191NCBI
Celera1432,602,359 - 32,611,369 (+)NCBI
Cytogenetic Map14q22.1NCBI
HuRef1432,895,105 - 32,904,115 (+)NCBIHuRef
CHM1_11452,673,595 - 52,682,607 (+)NCBICHM1_1
Ptgdr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21517,360,304 - 17,367,679 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1517,360,304 - 17,367,679 (+)Ensembl
Rnor_6.01519,195,606 - 19,196,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01523,162,010 - 23,162,912 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41519,345,555 - 19,352,929 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11519,345,554 - 19,352,929 (+)NCBI
Celera1517,315,866 - 17,323,221 (+)NCBICelera
Cytogenetic Map15p14NCBI
Ptgdr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540910,801,328 - 10,810,066 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540910,801,370 - 10,810,161 (-)NCBIChiLan1.0ChiLan1.0
PTGDR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11451,149,155 - 51,158,158 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1451,149,155 - 51,158,161 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01432,863,852 - 32,873,492 (+)NCBIMhudiblu_PPA_v0panPan3
PTGDR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1828,480,446 - 28,491,331 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl828,480,478 - 28,488,855 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha828,232,194 - 28,242,277 (+)NCBI
ROS_Cfam_1.0828,657,597 - 28,667,689 (+)NCBI
ROS_Cfam_1.0 Ensembl828,657,612 - 28,665,988 (+)Ensembl
UMICH_Zoey_3.1828,326,721 - 28,336,803 (+)NCBI
UNSW_CanFamBas_1.0828,387,594 - 28,397,684 (+)NCBI
UU_Cfam_GSD_1.0828,734,940 - 28,745,039 (+)NCBI
Ptgdr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864076,707,144 - 76,714,871 (-)NCBI
SpeTri2.0NW_0049366972,481,340 - 2,488,868 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGDR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12429,347,796 - 29,359,783 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2429,350,749 - 29,359,754 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605317,618,199 - 17,627,555 (+)NCBIVero_WHO_p1.0
Ptgdr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473116,776,050 - 16,785,178 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
PMC58788P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381444,858,634 - 44,858,746UniSTSGRCm38
MGSCv371445,478,309 - 45,478,421UniSTSGRCm37
Celera1441,052,569 - 41,052,681UniSTS
Cytogenetic Map14C1UniSTS
cM Map1413.5UniSTS
Ptgdr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381444,858,438 - 44,858,729UniSTSGRCm38
MGSCv371445,478,113 - 45,478,404UniSTSGRCm37
Celera1441,052,373 - 41,052,664UniSTS
Cytogenetic Map14C1UniSTS
cM Map1413.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)14870000046500000Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)14870000047000000Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141249091446491050Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined1254601848527625Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141543865949438808Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141910564753105769Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142101238271648361Mouse
14746973Manh76_mmandible shape 76 (mouse)142256526056565260Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492582457942312Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142820000060900000Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142975953763759676Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143009779364097924Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143009779364097924Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143060000048600000Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143060000052700000Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143060000087700000Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143350000059200000Mouse
27226727Tibl21_mtibia length 21, 16 week (mouse)143440000052700000Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143532384068548287Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143719272871192863Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4009986274099862Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144272496776725144Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144272496776725144Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144279982176799969Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144282839876828596Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144282839876828596Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:491
Count of miRNA genes:366
Interacting mature miRNAs:397
Transcripts:ENSMUST00000095959
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000095959   ⟹   ENSMUSP00000093653
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1445,088,692 - 45,096,832 (-)Ensembl
GRCm38.p6 Ensembl1444,851,235 - 44,859,375 (-)Ensembl
RefSeq Acc Id: NM_008962   ⟹   NP_032988
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391445,088,692 - 45,096,832 (-)NCBI
GRCm381444,851,235 - 44,859,375 (-)NCBI
MGSCv371445,470,910 - 45,479,050 (-)RGD
Celera1441,045,205 - 41,053,310 (-)RGD
cM Map14 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032988 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI32298 (Get FASTA)   NCBI Sequence Viewer  
  BAA06168 (Get FASTA)   NCBI Sequence Viewer  
  BAC27895 (Get FASTA)   NCBI Sequence Viewer  
  EDL20681 (Get FASTA)   NCBI Sequence Viewer  
  P70263 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_032988   ⟸   NM_008962
- UniProtKB: P70263 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000093653   ⟸   ENSMUST00000095959

Promoters
RGD ID:8682016
Promoter ID:EPDNEW_M19039
Type:multiple initiation site
Name:Ptgdr_1
Description:Mus musculus prostaglandin D receptor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381444,859,376 - 44,859,436EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102966 AgrOrtholog
Ensembl Genes ENSMUSG00000071489 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000093653 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000095959 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Pglndn_D_rcpt UniProtKB/Swiss-Prot
  Prostanoid_rcpt UniProtKB/Swiss-Prot
KEGG Report mmu:19214 UniProtKB/Swiss-Prot
MGD MGI:102966 ENTREZGENE
NCBI Gene 19214 ENTREZGENE
PANTHER PTHR11866 UniProtKB/Swiss-Prot
  PTHR11866:SF14 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PharmGKB PTGDR RGD
PhenoGen Ptgdr PhenoGen
PRINTS PROSTANOIDR UniProtKB/Swiss-Prot
  PRSTNOIDDPR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
UniProt P70263 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A2RSY4 UniProtKB/Swiss-Prot
  Q8CCM3 UniProtKB/Swiss-Prot