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Gene: Phlpp1 (PH domain and leucine rich repeat protein phosphatase 1) Mus musculus
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Symbol: Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Description: Predicted to have protein serine/threonine phosphatase activity. Involved in entrainment of circadian clock and regulation of T cell anergy. Predicted to localize to the cytoplasm; nucleus; and plasma membrane. Is expressed in ventricular layer. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; protein kinase C (PKC) signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI836256; mKIAA0606; PH domain leucine-rich repeat-containing protein phosphatase 1; PH domain-containing family E member 1; Phlpp; pleckstrin homology domain containing, family E (with leucine rich repeats) member 1; pleckstrin homology domain-containing family E member 1; Plekhe1; SCOP; suprachiasmatic nucleus circadian oscillatory protein
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1106,171,752 - 106,394,250 (+)Ensembl
GRCm381106,171,869 - 106,394,245 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371108,068,446 - 108,290,822 (+)NCBIGRCm37mm9NCBIm37
MGSCv361107,999,416 - 108,221,797 (+)NCBImm8
Celera1109,020,809 - 109,235,924 (+)NCBICelera
Cytogenetic Map1 E2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Phlpp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550945
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.